Interactions on record — worth a quick check against your medications. Based on 5 of 7 ingredients. Check your meds →
Dietary supplement

Super Colostrum 500 mg Ingredients & Drug Interactions

by NOW

Super Colostrum 500 mg label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Super Colostrum 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Super Colostrum 500 mg is a dietary supplement by NOW with 7 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,211 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Eleuthero, Astragalus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Super Colostrum 500 mg by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with Super Colostrum 500 mg by NOW — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Super Colostrum 500 mg by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 5 active ingredients. Eleuthero (also called Siberian ginseng) and astragalus are traditional immune-supporting herbs; larch arabinogalactan (labeled as ImmunEnhancer) is a fiber that may support immune function; olive leaf extract rounds out the blend.

The fifth active ingredient is dried bovine colostrum, which comes from cow's milk produced right after birth and contains immune-related proteins and growth factors. The capsule itself contains several inactive ingredients — hypromellose (the capsule material), maltodextrin, milk protein concentrate, magnesium stearate, silicon dioxide, medium chain triglyceride, sunflower lecithin, and natural vanilla flavor.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: immune system support.
  • We looked for evidence on: Common cold, Influenza, Upper respiratory tract infection (URTI), Exercise-induced respiratory infections, Coronavirus disease 2019 (COVID-19), Allergic rhinitis (hay fever) — and 4 related terms.
  • The closest evidence on file: Olive is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced respiratory infections (Natural Medicines).
  • Also on file: Olive is rated "Insufficient Reliable Evidence To Rate" for Influenza.
  • Also on file: Astragalus is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever), Asthma, Upper respiratory tract infection (URTI).

The evidence we hold doesn't establish that this product works for a specific condition. Eleuthero shows possibly effective evidence only for genital herpes; the rest of its uses in our data (chronic fatigue, osteoporosis, bipolar disorder, and familial Mediterranean fever) lack reliable evidence.

Astragalus, larch arabinogalactan, and olive leaf all have insufficient evidence for the conditions listed in our data — ranging from common cold and allergic rhinitis to osteoarthritis and dyspepsia. We hold no effectiveness data for bovine colostrum.

The evidence, ingredient by ingredient Black Psyllium Eleuthero Astragalus Larch Arabinogalactan Olive

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Eleuthero is generally well tolerated for short-term use, though long-term safety evidence is limited. Common short-term side effects include diarrhea, nausea, headache, stomach upset, and a rash.

Nervousness occurs in some people (reported in about 7% in one study), especially at higher doses, and it may raise blood pressure — something to watch if you already have high blood pressure. Astragalus is also generally well tolerated short-term in healthy adults, though quality human safety data are sparse; dizziness has been reported rarely.

Larch arabinogalactan is generally well tolerated as a fiber, but some people experience bloating and gas. Olive leaf seems well tolerated, with headache and stomach discomfort the most commonly reported effects; olive tree pollen can trigger seasonal allergies.

The safety data for concentrated olive supplements is limited compared to olives and olive oil as food. Pregnancy and breastfeeding: the safety data advises against eleuthero, astragalus, and concentrated olive supplements during pregnancy and breastfeeding.

Larch arabinogalactan has insufficient data — talk with your doctor or pharmacist for personalized advice. We hold no safety data on bovine colostrum in pregnancy or breastfeeding.

Side effects, ingredient by ingredient Black Psyllium Eleuthero Astragalus Larch Arabinogalactan Olive

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Black Psyllium, Astragalus, Larch Arabinogalactan, Eleuthero.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,212 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take blood thinners (like warfarin or clopidogrel), diabetes medications, immunosuppressants (like cyclosporine or azathioprine), lithium, or digoxin (Lanoxin). Eleuthero may also theoretically affect how your liver processes certain drugs, and both eleuthero and astragalus may lower blood sugar — more reason to review your medication list with your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is an immune-support blend best suited for short-term use in otherwise healthy adults. If you take any blood thinner, diabetes medication, immunosuppressant, or lithium, you need to check with your pharmacist before starting — several ingredients in this product may interact with those drugs.

Pregnant or breastfeeding? Skip this one or talk to your doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Colostrum 500 mg, straight from the product label.

Brand NOW
Barcode (UPC) 733739032324
Net contents 90 Veg Capsule(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 314086
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Halal, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Colostrum 500 mg by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veg Capsule(s)
Maximum serving Sizes:
2 Veg Capsule(s)
Servings per container
45
UPC/BARCODE
733739032324
IngredientAmount% DV
Calories5 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Dietary Fiber1 Gram(s)2%
Protein1 Gram(s)--
Eleuthero100 mg--
Astragalus100 mg--
ImmunEnhancer200 mg--
Olive200 mg--
dried Bovine Colostrum1 Gram(s)--

Other ingredients: Hypromellose, Maltodextrin, Milk Protein concentrate, Magnesium Stearate, Silicon Dioxide, Medium Chain Triglyceride, Sunflower Lecithin, natural Vanilla flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 2 capsules twice daily, preferably before meals.

Formula

NOW Super Colostrum combines colostrum with the herbal ingredients, larch arabinogalactan, olive leaf and astragalus to maximize immune system support. Colostrum has naturally occurring immunoglobulins IgG, IgM and IgA, which are important immunological proteins for both animals and humans. In addition, NOW has also included eleuthero to support a healthy response to typical, everyday stress.

Naturally occurring immunoglobulins Super Colostrum with ImmunEnhancer, Olive leaf extract and Astragalus root

Triangle K D (Kosher Dairy)

Crescent H (Halal)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only. Keep out of reach of children.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Avoid taking if lactose intolerant and/or sensitive to dairy products.

Not manufactured with wheat, gluten, soy, egg, fish, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Contains milk.

Formulation

Not manufactured with wheat, gluten, soy, egg, fish, shellfish or sesame ingredients.

Supports immune function

Non-GMO

Made and quality tested in the USA with globally sourced ingredients. Natural color variation may occur in this product.

EUA # 1482865

Brand IP Statement(s)

Immunenhancer is a Lonza trademark.

General Statements

This bottle is made from 100% PCR (post-consumer recycled) resin.

General Health

Family owned since 1968.

FDA Statement of Identity

A Dietary Supplement

Seals/Symbols

Triangle K D (Kosher Dairy)

GMP Quality Assured Crescent H (Halal)

Storage

Store in a cool, dry place after opening.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Super Colostrum 500 mg by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Super Colostrum 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Super Colostrum 500 mg by NOW

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Veg Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Protein

1 Gram(s) per serving

Eleuthero

Interacts with
1,140 drugs
100 mg per serving

Eleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress. The scientific evidence beh...

Eleuthero monograph & interactions

Astragalus

Interacts with
208 drugs
100 mg per serving

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...

Astragalus monograph & interactions

ImmunEnhancer

Interacts with
121 drugs
200 mg per serving Form: Larch Tree

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but...

ImmunEnhancer monograph & interactions

Olive

No known
interactions
200 mg per serving Form: Oleuropein

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Olive monograph & interactions

Dried Bovine Colostrum

1 Gram(s) per serving

Other (inactive) ingredients: Hypromellose, Maltodextrin, Milk Protein concentrate, Magnesium Stearate, Silicon Dioxide, Medium Chain Triglyceride, Sunflower Lecithin, Natural Vanilla flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Colostrum 500 mg by NOW Drug Interactions

Want to check YOUR meds against Super Colostrum 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,211Drugs
681 Moderate 1,530 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Eleuthero 1,140
Astragalus 208
ImmunEnhancer 121

Individual Drug Interactions

The ingredients in Super Colostrum 500 mg interact with 2,211 drugs. Click any drug to see the details.

4 of the 7 ingredients in Super Colostrum 500 mg interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Eleuthero Astragalus ImmunEnhancer

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Colostrum 500 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Eleuthero10 drug types · 1,140 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, eleuthero may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that a constituent of eleuthero, dihydroxybenzoic acid, appears to inhibit platelet aggregation. Concomitant use with anticoagulant or antiplatelet drugs might increase the risk of bleeding. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, eleuthero might have additive effects when used with antidiabetes drugs.
Animal research suggests that certain constituents of eleuthero have hypoglycemic activity in both healthy and diabetic animals. A small study in adults with type 2 diabetes also shows that taking eleuthero for 3 months can lower blood glucose levels. However, one very small study in healthy individuals shows that taking powdered eleuthero 3 grams, 40 minutes prior to a 75-gram oral glucose tolerance test, significantly increases postprandial blood glucose levels when compared with placebo. These contradictory findings might be due to patient-specific variability and variability in active ingredient ratios.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
In vitro and animal research suggest that standardized extracts of eleuthero inhibit CYP1A2. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP2C9.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP2C9. This effect has not been reported in humans.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Eleuthero might increase serum digoxin levels and increase the risk of side effects.
In one case report, a 74-year-old male who was stabilized on digoxin presented with an elevated serum digoxin level after starting an eleuthero supplement, without symptoms of toxicity. After stopping the supplement, serum digoxin levels returned to normal. It is not clear whether this was due to a pharmacokinetic interaction or to interference with the digoxin assay. Although the product was found to be free of digoxin and digitoxin, it was not tested for other contaminants.

Likelihood Unlikely Evidence D
Immunosuppressants

Theoretically, eleuthero might interfere with immunosuppressive drugs because of its immunostimulant activity.
Animal and in vitro research shows that eleuthero extracts have immunomodulatory effects, including increasing cellular and humoral activity.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, eleuthero might increase levels of P-glycoprotein substrates.
In vitro research suggests that eleuthero can inhibit the multi-drug transporter protein, P-glycoprotein. However, it is too soon to tell if this is clinically important. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP2D6.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP2D6. However, research in healthy human volunteers has found that taking eleuthero 485 mg twice daily for 14 days does not inhibit CYP2D6 drug metabolism.

Likelihood Unlikely Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP3A4. However, research in healthy human volunteers has found that taking eleuthero 485 mg twice daily for 14 days does not inhibit CYP3A4 drug metabolism.

Likelihood Unlikely Evidence B
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Theoretically, eleuthero might decrease levels of drugs metabolized by OATP.
In vitro research suggests that eleuthero inhibits OATP2B1, which might reduce the bioavailability of oral drugs that are substrates of OATP2B1. Due to the weak inhibitory effect identified in this study, this interaction is not likely to be clinically significant.

Likelihood Possible Evidence D
Eleuthero full monograph & interactions

Astragalus4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
Astragalus full monograph & interactions

ImmunEnhancer1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D
ImmunEnhancer full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Super Colostrum 500 mg, from the product label.

NOW

See all NOW products
Name
NOW FOODS
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

Super Colostrum 500 mg by NOW: Common Questions

Does Super Colostrum 500 mg by NOW interact with any medications?
Yes. Based on its ingredients, Super Colostrum 500 mg has a known interaction with 2,211 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Colostrum 500 mg contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood thinner?
Not without checking first. Eleuthero in this product may theoretically increase bleeding risk if you're on a blood thinner like warfarin or aspirin. Talk to your pharmacist before you start — they can review your specific medication and dose.
What are the most common side effects I might notice?
From eleuthero, you might experience diarrhea, nausea, headache, or stomach upset, especially short-term. Nervousness or anxiety can occur, particularly at higher doses. Larch arabinogalactan may cause bloating and gas. Olive leaf sometimes causes headache or stomach discomfort.
Is this safe to take long-term?
The safety data we hold is strongest for short-term use. Long-term safety for eleuthero and astragalus is less well studied in humans, and high-quality long-term safety data for larch arabinogalactan are limited. If you're thinking of using it beyond a few weeks, check with your pharmacist.
Can I take this if I'm diabetic and on diabetes medication?
Both eleuthero and astragalus may lower blood sugar. Combined with your diabetes medication, there's a theoretical risk of your blood sugar dropping too low. Talk to your pharmacist or doctor before starting — they may want to monitor your levels.
Is this okay during pregnancy or while breastfeeding?
No — the safety data advises against eleuthero, astragalus, and concentrated olive supplements during pregnancy and breastfeeding. Larch arabinogalactan has insufficient data, so talk with your doctor for personalized advice.
What does each ingredient actually do?
Eleuthero and astragalus are traditional immune-supporting herbs. Larch arabinogalactan is a plant fiber meant to support immune function. Olive leaf extract is included for its antioxidant properties. Bovine colostrum is the nutrient-rich milk produced by cows right after birth. None of these have proven effectiveness for a specific condition based on the evidence we hold.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Colostrum 500 mg label
Go deeper

The Full Monographs Behind Super Colostrum 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Eleuthero

Interacts with 1,140 drugs

Eleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress. The scientific evidence behind these uses is limited and mixed, so...

Read the full Eleuthero monograph → Herb & supplement monograph

Astragalus

Interacts with 208 drugs

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...

Read the full Astragalus monograph → Herb & supplement monograph

Larch Arabinogalactan

Interacts with 121 drugs

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but limited, and most claims are not yet fi...

Read the full Larch Arabinogalactan monograph → Herb & supplement monograph

Olive

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyrosol. Olive oil as part of a Mediterrane...

Read the full Olive monograph →
Sources

Sources & How We Checked

Super Colostrum 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 65 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
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Eleuthero 24 references
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Astragalus 13 references
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Larch Arabinogalactan 8 references
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Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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