Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Tru-Sorb Premium Hemp Oil Ingredients & Drug Interactions

by Rawleigh

Tru-Sorb Premium Hemp Oil label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tru-Sorb Premium Hemp Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tru-Sorb Premium Hemp Oil is a dietary supplement by Rawleigh with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are VESIsorb HEMPCHOICE PCR Hemp Oil extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Tru-Sorb Premium Hemp Oil by Rawleigh

Ask about any prescription or over-the-counter medication and we check it for interactions with Tru-Sorb Premium Hemp Oil by Rawleigh — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Tru-Sorb Premium Hemp Oil by Rawleigh

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Tru-Sorb Premium Hemp Oil is a single-ingredient product: a hemp oil extract delivered in what's called a colloidal system—basically a way to help your body absorb it better. The capsule shell is the inactive component.

That's it—no fillers or binders mixed in.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hemp product and its label doesn't state a use — see Hemp's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for what this hemp oil does isn't established in our data. We hold effectiveness ratings for constipation, eczema, and familial high cholesterol (a genetic lipid condition), but for all of them the evidence is insufficient to rate whether it works.

If you're considering it for another reason, that data isn't on file here.

The evidence, ingredient by ingredient Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed foods in normal amounts are generally well tolerated, but concentrated extracts like this one are less studied, so caution is advised. In larger doses, hemp seed oil appears well tolerated overall.

Rare serious side effects reported include allergic reactions (hives, facial swelling, shortness of breath, and in very rare cases anaphylaxis), and isolated cases of liver enzyme changes and hepatitis, mainly at very high doses in young children. Allergy to hemp seed is uncommon but has been documented.

Side effects, ingredient by ingredient Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 939 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using this product if you take estrogens or hormone therapy (Moderate interaction). Also double-check if you're on blood pressure medications, blood thinners, or drugs your liver processes through CYP1A2 or CYP3A4 enzymes (all Minor interactions).

No interactions are documented for ingredients we could not check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a single-ingredient hemp oil extract in a delivery system designed for absorption. If you take estrogen therapy, blood pressure medications, blood thinners, or drugs metabolized through your liver's CYP1A2 or CYP3A4 pathways, check your exact medications with your doctor or pharmacist before starting.

Concentrated hemp extracts are less studied than food forms, so talk it over with your healthcare provider about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tru-Sorb Premium Hemp Oil, straight from the product label.

Brand Rawleigh
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Sep 21, 2018
DSLD ID 181044
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tru-Sorb Premium Hemp Oil by Rawleigh, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
IngredientAmount% DV
VESIsorb HEMPCHOICE PCR Hemp Oil extract334 mg--

Other ingredients: VESIsorb Colloidal Delivery System, Capsule Shell

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Optimal absorption and bioavailability

Serving your family with pride since 1889 Rawleigh

Home remedies

Made in the USA

Brand IP Statement(s)

Tru-Sorb Premium Hemp Oil utilizes a patented colloidal droplet delivery system for dramatically improved absorption.

Tru-Sorb uses VESIsorb a patented colloidal droplet delivery system. VESIsorb is a registered trademark of SourceOne Global Partners.

Suggested/Recommended/Usage/Directions

Suggested use: Take one (1) softgel daily or as directed by your healthcare professional or pharmacist.

Precautions

Caution: Consult your physician before taking if you are pregnant, nursing, or have any pre-existing medical conditions.

Keep out of the reach of children

Do not use if seal is damaged or missing

Storage

Store in a cool, dry place

FDA Disclaimer Statement

This product has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

General

Item# 102152 090816/9102XXXA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tru-Sorb Premium Hemp Oil by Rawleigh label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tru-Sorb Premium Hemp Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tru-Sorb Premium Hemp Oil by Rawleigh

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

VESIsorb HEMPCHOICE PCR Hemp Oil extract

Interacts with
938 drugs
334 mg per serving Form: Beta-Caryophyllene, Cannabidiol, Limonene, Phytocannabinoids, Terpenes

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

VESIsorb HEMPCHOICE PCR Hemp Oil extract monograph & interactions

Other (inactive) ingredients: VESIsorb Colloidal Delivery System, Capsule Shell. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tru-Sorb Premium Hemp Oil by Rawleigh Drug Interactions

Want to check YOUR meds against Tru-Sorb Premium Hemp Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
938Drugs
41 Moderate 897 Minor

Ingredients driving the most interactions

VESIsorb HEMPCHOICE PCR Hemp Oil extract 938

Individual Drug Interactions

The ingredients in Tru-Sorb Premium Hemp Oil interact with 938 drugs. Click any drug to see the details.

1 of the 1 ingredient in Tru-Sorb Premium Hemp Oil interact with drugs. Each result below shows which ingredient is responsible. VESIsorb HEMPCHOICE PCR Hemp Oil extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Tru-Sorb Premium Hemp Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

VESIsorb HEMPCHOICE PCR Hemp Oil extract6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
VESIsorb HEMPCHOICE PCR Hemp Oil extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tru-Sorb Premium Hemp Oil, from the product label.

Rawleigh

See all Rawleigh products
Name
W.T. Rawleigh
City
West Palm Beach
State
FL
ZipCode
33407
Phone Number
866-354-8384
Web Address
www.vitaminsdirectonline.com
Pharmacist Counseling Corner

Tru-Sorb Premium Hemp Oil by Rawleigh: Common Questions

Does Tru-Sorb Premium Hemp Oil by Rawleigh interact with any medications?
Yes. Based on its ingredients, Tru-Sorb Premium Hemp Oil has a known interaction with 938 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tru-Sorb Premium Hemp Oil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe if I'm taking blood pressure medication?
Hemp seed protein has shown ACE inhibitor-like effects in animal studies, meaning it might lower blood pressure further if combined with your medication. This is documented as a Minor interaction, so talk with your doctor or pharmacist before starting—they'll know your specific drug and blood pressure numbers.
Can I take this with a blood thinner like warfarin or aspirin?
Hemp seed showed platelet-inhibiting effects in animal studies, which theoretically could increase bleeding risk with blood thinners. Human studies so far haven't confirmed this, but it's listed as a Minor interaction. Check with your doctor or pharmacist before combining them.
What are the common side effects?
Hemp seed oil appears well tolerated in larger amounts. Allergy to hemp is uncommon, but when it does occur it can cause hives, facial swelling, or shortness of breath. Rare serious cases like anaphylaxis have been reported.
Is this okay to take while on hormone therapy?
This is the most serious interaction documented for this product: a Moderate interaction with estrogens. Animal research suggests hemp may affect estrogen levels, though we don't yet understand exactly how or whether it happens in humans. Talk with your doctor before starting.
Can I use this if I have a hemp allergy?
No. Hemp seed allergy, while uncommon, can cause serious reactions including facial swelling, breathing problems, and rarely anaphylaxis. If you've had any allergic reaction to hemp or cannabis products, avoid this.
Does this product actually work for anything?
We hold effectiveness ratings for constipation, eczema, and familial high cholesterol, but for all three the evidence is insufficient to say whether this product works. If you're interested in it for another reason, we don't have that data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tru-Sorb Premium Hemp Oil is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tru-Sorb Premium Hemp Oil label
Go deeper

The Full Monographs Behind Tru-Sorb Premium Hemp Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hemp

Interacts with 938 drugs

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...

Read the full Hemp monograph →
Sources

Sources & How We Checked

Tru-Sorb Premium Hemp Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team