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Dietary supplement

Wild Blueberry Ingredients & Drug Interactions

by MegaFood

Tablet Or Pill Category: Botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Wild Blueberry is a dietary supplement by MegaFood with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, heart health, brain and memory health.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Wild Blueberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Wild Blueberry by MegaFood

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “FoodState Nutrients” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This product contains one active ingredient: wild blueberry, a whole-food ingredient that delivers the natural compounds found in the fruit. The tablet also includes two inactive ingredients — vegetable lubricant and silica — which are standard binders and flow agents that help form the pill.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Blueberry product and its label doesn't state a use — see Blueberry's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for wild blueberry is mixed. For high blood pressure (hypertension), the data actually suggests it's likely ineffective.

For age-related cognitive decline, anxiety, athletic performance, and high cholesterol (hyperlipidemia), we don't have enough reliable evidence to rate whether it works. Cardiovascular disease prevention also lacks sufficient evidence in our data.

If you're considering this for one of these conditions, talk to your pharmacist or doctor about what the research really supports.

The evidence, ingredient by ingredient Blueberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberries as food are widely eaten and generally well tolerated. When you take this supplement as a tablet, the same safety profile mostly holds — though freeze-dried blueberries in concentrated form may cause constipation, diarrhea, nausea, or vomiting in some people.

In one clinical trial, about a quarter of participants taking 50 grams daily stopped in the first week due to stomach upset. For pregnancy and breastfeeding, eating whole blueberries is fine, but high-dose concentrated supplements haven't been well studied.

The safety data rates this product as likely safe in pregnancy and lactation, but the evidence for extracts at supplement levels is incomplete. If you're pregnant or nursing, discuss it with your doctor or pharmacist first.

Side effects, ingredient by ingredient Blueberry

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blueberry.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check if you're on antidiabetes drugs (blood sugar medications), flurbiprofen or other anti-inflammatory pain relievers, or buspirone for anxiety. Blueberry may theoretically increase your risk of low blood sugar with diabetes drugs and may raise blood levels of the other two medications.

No interactions are documented for the inactive ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Wild blueberry from MegaFood is a whole-food supplement that's generally well tolerated, though it can cause digestive upset in some people. If you take diabetes medications, anti-inflammatories, or anti-anxiety drugs, check your exact medications with our tool before starting.

Anyone pregnant or breastfeeding should confirm with their pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wild Blueberry, straight from the product label.

Brand MegaFood
Barcode (UPC) 051494102336
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Jul 25, 2016
DSLD ID 62698
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wild Blueberry by MegaFood, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Chewable Tablet(s)
Maximum serving Sizes:
1 Chewable Tablet(s)
Servings per container
60
UPC/BARCODE
051494102336
IngredientAmount% DV
FoodState Nutrients0 NP--
Wild Blueberry336 mg--

Other ingredients: Vegetable Lubricant, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Tested free pesticides & herbicides

Non GMO project Verified Nongmoproject.org

NSF Certified Gluten-free

V Certified vegan vegan.org

Soy free

Dairy free

Farm fresh

OK

General

F3991B Rev: 19 10/15

Brand IP Statement(s)

Fresh from farm to tablet

FoodState Nutrients are made with fresh, real foods to provide essential vitamins and minerals that are easy-to-digest and gentle on the body, even when taken on an empty stomach.

General Statements

Nourish - Protect - Renew

60 Servings

One MegaFood Wild Blueberry Tablet is Equivalent to approximately 6-7 Fresh Wild Blueberries.

MegaFood cares about doing things the right way – we refuse to take shortcuts, and we never compromise on quality or the things that matter. Since 1973, we have been going out of our way to source fresh and local foods from trusted farmers. We then make our wholesome supplements using our one-of-a-kind process to deliver the most authentic nutrition – much more than vitamins alone.

Please recycle

FDA Statement of Identity

Whole Food Dietary Supplement

Formulation

Non GMO

NSF Certified Gluten-free

V Certified vegan vegan.org

Tested free pesticides & herbicides

Soy free

Dairy free

Formula

OK

Suggested/Recommended/Usage/Directions

Suggested Use: Chew 1 tablet daily. May be taken anytime throughout the day, even on an empty stomach.

See for yourself

Wild Blueberry by MegaFood label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Wild Blueberry by MegaFood

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Chewable Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

FoodState Nutrients

0 NP per serving

Other (inactive) ingredients: Vegetable Lubricant, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wild Blueberry by MegaFood Drug Interactions

Want to check YOUR meds against Wild Blueberry?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
88Drugs
88 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Wild Blueberry with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wild Blueberry3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Wild Blueberry, from the product label.

MegaFood

See all MegaFood products
Name
MegaFood
Street Address
PO Box 325
City
Derry
State
NH
ZipCode
03038
Phone Number
800-848-2542
Web Address
megafood.com
Pharmacist Counseling Corner

Wild Blueberry by MegaFood: Common Questions

Does Wild Blueberry by MegaFood interact with any medications?
Yes. Based on its ingredients, Wild Blueberry has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wild Blueberry contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have diabetes?
Blueberry may theoretically increase the risk of low blood sugar when taken with diabetes medications. Check with your pharmacist before starting, especially if you're already on a diabetes drug — they can monitor your blood sugar and adjust your dose if needed.
What side effects should I watch for?
Most people tolerate blueberry well. The main side effects are digestive: constipation, diarrhea, nausea, and vomiting. In one study, about a quarter of people taking a high dose (50 grams daily) had stomach upset bad enough to stop. Start with a lower dose and see how you feel.
Is it safe to take while pregnant or breastfeeding?
The data rates this product as likely safe in pregnancy and lactation, but concentrated blueberry supplements haven't been studied well at high doses in these situations. Eating whole blueberries is fine, but talk to your doctor or pharmacist about whether the supplement form is right for you.
Does wild blueberry help with memory or brain health?
We don't have enough reliable evidence to say whether blueberry helps with age-related cognitive decline. The research isn't established in our data, so talk to your doctor if that's why you're interested.
Can this help lower my cholesterol or blood pressure?
For high cholesterol, we don't have enough evidence to rate it. For high blood pressure, the evidence actually suggests blueberry is likely ineffective. It's not a substitute for your prescribed medications or your doctor's treatment plan.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wild Blueberry is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wild Blueberry label
Sources

Sources & How We Checked

Wild Blueberry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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