Theophylline

Name: Theophylline Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

46 interactions 1 explained in plain English

Also sold as: Accurbron® Aerolate® Aquaphyllin® Asbron® Bronkodyl® Duraphyl® Elixicon® Elixomin® Elixophyllin Elixophyllin® Labid® Lanophyllin® Quibron-T® Slo-Bid® Slo-Phyllin® Somophyllin® Sustaire® Synophylate® T-Phyll® Theo-24 Theo-24® Theo-Dur® Theobid® Theochron® Theoclear® Theolair® Theolixir® Theophyl® Theovent® Uni-dur® Uniphyl®

About Theophylline

Theophylline is a bronchodilator medication used to prevent and treat wheezing, shortness of breath, and chest tightness caused by lung diseases like asthma and chronic bronchitis. Read the full Theophylline drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Medroxyprogesterone Adalimumab Injection Capmatinib Levofloxacin Injection Estradiol Transdermal Patch Peginterferon Alfa-2A Injection

18 Major 18 Moderate 10 Minor

All (46) Major (18) Moderate (18) Minor (10)

Minor

Theophylline Felodipine Plendil® A decrease of theophylline efficacy Details Theophylline Furosemide Injection Disal Altered theophylline concentrations Details Theophylline Nifedipine Adalat® Alterations of the theophylline serum concentration Details Theophylline Ofloxacin Floxin® An increased risk of elevated theophylline concentrations Details Theophylline Ofloxacin Ophthalmic Ocuflox An increased risk of elevated theophylline concentrations Details Theophylline Ofloxacin Otic Floxin® Otic An increased risk of elevated theophylline concentrations Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.