Aconite + Ceftolozane Sulfate, Tazobactam Sodium
Ceftolozane Sulfate, Tazobactam Sodium brand name: Zerbaxa.
We found no known interaction between Aconite and Ceftolozane Sulfate, Tazobactam Sodium in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Aconite and Ceftolozane Sulfate, Tazobactam Sodium
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Ceftolozane Sulfate, Tazobactam Sodium and Aconite in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Aconite safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Ceftolozane Sulfate, Tazobactam Sodium
Interactions in our licensed database are recorded against drug classes, not just single drug names. Ceftolozane Sulfate, Tazobactam Sodium is filed under a single classification — antibiotic drugs. Aconite has documented interactions with 2 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate) and stimulant drugs (moderate) — and none of Ceftolozane Sulfate, Tazobactam Sodium’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Aconite Does Interact With Other Medications
Aconite has 278 moderate known drug interactions in our database — Ceftolozane Sulfate, Tazobactam Sodium isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Aconite
We haven’t checked that one against Aconite yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Aconite. Pick one to open its full report.
Aconite in Pregnancy & Breastfeeding
When used orally or topically.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
What Ceftolozane Sulfate, Tazobactam Sodium Is Prescribed For, and What Aconite Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Ceftolozane Sulfate, Tazobactam Sodium is a prescription medicine with approved uses on its FDA label. Aconite is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Ceftolozane Sulfate, Tazobactam Sodium is prescribed for: Zerbaxa (ceftolozane and tazobactam) is used to treat three types of serious bacterial infections in adults and children born at least 32 weeks gestational age. For complicated intra-abdominal infections (serious infections inside the belly), Zerbaxa is always given alongside another antibiotic called metronidazole. It also treats complicated urinary tract infections, including kidney infections (pyelonephritis). Zerbaxa is also approved to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia — lung infections that develop in the hospital or while a patient is on a breathing machine.
Read the rest of what Ceftolozane Sulfate, Tazobactam Sodium is prescribed for
It works only against specific bacteria confirmed or strongly suspected to be causing the infection.
Aconite has been studied for:
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Pneumonia studied, not established Aconite has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Aconite for pneumonia
Injectable aconite has only been evaluated in combination with other ingredients; its effect when used alone is unclear. Oral aconite has not been evaluated for this use.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Ceftolozane Sulfate, Tazobactam Sodium on your own; if you are taking Aconite for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
See Every Supplement That Interacts With Ceftolozane Sulfate, Tazobactam Sodium
This page covers Aconite only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ceftolozane Sulfate, Tazobactam Sodium page lists 27 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Bacillus Coagulans (moderate), Bacillus Subtilis (moderate), Bifidobacterium Animalis Subsp. Lactis (moderate), Bifidobacterium Bifidum (moderate) and Bifidobacterium Breve (moderate).
By severity: 26 moderate · 1 minor.
From our pharmacist’s overview on the Ceftolozane Sulfate, Tazobactam Sodium page
“The supplement interactions on file for Zerbaxa (ceftolozane and tazobactam) all point in one direction, and it is not toward harming you. Every entry is a probiotic or fermented product, things like Lactobacillus acidophilus or fermented milk drinks, and the concern is that this potent antibiotic can kill the live organisms in those p…”
Reviewed by 2 · Jul 18, 2026
Open the Ceftolozane Sulfate, Tazobactam Sodium interaction page
Taking Aconite as Part of a Dietary Supplement Product? Check It for Interactions
We hold 56 real supplement products containing Aconite, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Aconite. Even though Aconite itself has no known interaction with Ceftolozane Sulfate, Tazobactam Sodium, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Aconite and Ceftolozane Sulfate, Tazobactam Sodium Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#481 of 1,452 supplements looked up here in the last 7 days
#422 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Aconite reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Aconite and Ceftolozane Sulfate, Tazobactam Sodium records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Aconite
What is Aconite?
- Pain and nerve pain
- Fever and cold or flu symptoms
- Anxiety and restlessness (homeopathic use)
- Inflammation and joint pain
- Heart-related complaints (traditional use)
Aconite is a highly poisonous plant, and even small amounts of the raw or improperly processed root can cause severe, life-threatening reactions. There is no good scientific evidence that it safely treats any condition, and the only forms generally considered acceptable are extremely diluted homeopathic preparations. We strongly recommend avoiding raw or unprocessed aconite entirely and talking to a pharmacist or doctor before using any product containing it.
Aconitum napellus · Ranunculaceae · Root (and sometimes leaves), usually after processing · Highly diluted homeopathic pellets and liquids; processed roots in some traditional Asian medicine systems
An interaction check asks whether these two react with each other — it does not ask whether Aconite is a good idea for someone in your situation. Here is what our Aconite record says about it on its own.
Aconite: dosing
There is no safe, established standard dose of aconite for any condition. The line between a "traditional" amount and a deadly amount is extremely thin, which is a major reason this plant is considered so dangerous.The only forms generally considered acceptable are extremely diluted homeopathic products, which contain little or no actual plant material. If you choose to use such a product, follow the label exactly and do not exceed it.
From our Aconite monograph — the full record covers uses, side effects and every documented interaction.
About Ceftolozane and Tazobactam Injection
What Is Ceftolozane and Tazobactam Injection Used For?
Brand name: Zerbaxa
Zerbaxa (ceftolozane and tazobactam) is used to treat three types of serious bacterial infections in adults and children born at least 32 weeks gestational age. For complicated intra-abdominal infections (serious infections inside the belly), Zerbaxa is always given alongside another antibiotic called metronidazole. It also treats complicated urinary tract infections, including kidney infections (pyelonephritis).
Zerbaxa is also approved to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia — lung infections that develop in the hospital or while a patient is on a breathing machine. It works only against specific bacteria confirmed or strongly suspected to be causing the infection.
Other Drugs & Aconite
Browse every other medication we’ve checked against Aconite — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
278 interactions
- Diclofenac Sodium ›
- Ibuprofen ›
- Phentermine ›
- Aspirin ›
- Methylphenidate ›
- Naproxen ›
- Minocycline ›
- Phenylpropanolamine ›
- Nicotine ›
- Diclofenac Potassium ›
- Dipyridamole ›
- Phenylephrine ›
- Pseudoephedrine ›
- Amphetamine ›
- Diethylpropion ›
- Ketoprofen ›
- Bivalirudin ›
- Caffeine (otc Drug) ›
- Modafinil ›
- Oxymetazoline Hydrochloride ›
- Warfarin Sodium ›
- Amphetamine Sulfate ›
- Bromfenac Sodium ›
- Caffeine (prescription Drug) ›
- Cocaine Hydrochloride (prescription Drug) ›
- Dabigatran ›
- Diclofenac Epolamine ›
- Ephedrine Sulfate ›
- Iloprost ›
- Methylphenidate Hydrochloride ›
- Pemoline ›
- Piroxicam ›
- Pseudoephedrine Sulfate ›
- Streptokinase ›
- Ticlopidine ›
- Treprostinil (oral) ›
- Abciximab ›
- Abrocitinib ›
- Acenocoumarol ›
- Acetylsalicylic Acid ›
- Ambenonium Chloride ›
- Anacaulase-bcdb ›
- Anagrelide ›
- Anisindione ›
- Antithrombin Iii ›
- Apixaban ›
- Argatroban ›
- Armodafinil ›
- Betrixaban ›
- Cablivi ›
- Cangrelor ›
- Cilostazol ›
- Clopidogrel ›
- Dalteparin ›
- Danaparoid ›
- Defibrotide Sodium ›
- Dexamfetamine ›
- Dexmethylphenidate ›
- Dextroamphetamine ›
- Dextroamphetamine (patch) ›
Showing 60 of 278 moderate interactions — see all 278 on the Aconite page.
No interaction 2,551 drugs checked — show the list
We also checked Aconite against these medications and found no known interaction in our sources. Open any page to confirm.
- Levothyroxine ›
- Amlodipine ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Metoprolol ›
- Acetaminophen ›
- Abemaciclib ›
- Rosuvastatin ›
- Escitalopram ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Hydroxyurea ›
- Valacyclovir ›
- Semaglutide ›
- Sumatriptan ›
- Prednisone ›
- Propranolol ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Amitriptyline ›
- Methotrexate ›
- Bupropion ›
- Isotretinoin ›
- Bendamustine ›
- Amlodipine Besylate ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Pregabalin ›
- Lamotrigine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Methylene Blue ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Citalopram ›
- Buspirone ›
- Ciprofloxacin ›
- Levothyroxine, Liothyronine ›
- Bisoprolol ›
- Candesartan Cilexetil ›
- Acetaminophen, Oxycodone ›
- Diazepam ›
- Dapsone ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Amoxicillin, Clavulanate Potassium ›
- Cyclopentolate ›
- Cephalexin ›
- Atorvastatin Calcium ›
- Mannitol ›
- Roxithromycin ›
Showing the 60 most looked-up of 2,551 medications checked with no known interaction — see the full Aconite list.
Aconite References
The 33 references that drive our Aconite monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Tai YT. Adverse effects from traditional Chinese medicine. Lancet 1993;341:892.
- Tai YT, But PP, Young K, et al. Cardiotoxicity after accidental herb-induced aconite poisoning. Lancet 1992;340:1254-6. PubMed
- Fatovich DM. Aconite: a lethal Chinese herb. Ann Emerg Med 1992;21:309-11. PubMed
- Tomlinson B, Chan TY, Chan JC, Critchley JA. Herb-induced aconite poisoning. Lancet 1993;341:370-1. .
- Chan TY, Tomlinson B, Critchley JA. Aconitine poisoning following the ingestion of Chinese herbal medicines: a report of eight cases. Aust N Z J Med 1993;23:268-71. PubMed
- Yeih DF, Chiang FT, Huang SKS. Successful treatment of aconitine induced life threatening ventricular tachyarrhythmia with amiodarone. Heart 2000;84:E8. PubMed
- But PP, Tai YT, Young K. Three fatal cases of herbal aconite poisoning. Vet Hum Toxicol 1994;36:212-5.
- Feldkamp A, Koster B, Weber HP. [Fatal poisoning caused by aconite monk's hood]. Monatsschr Kinderheilkd 1991;139:366-7.
- Lin CC, Chan TY, Deng JF. Clinical features and management of herb-induced aconitine poisoning. Ann Emerg Med 2004;43:574-9. PubMed
- Poon WT, Lai CK, Ching CK, et al. Aconite poisoning in camouflage. Hong Kong Med J 2006;12:456-9.
- Guha, S., Dawn, B., Dutta, G., Chakraborty, T., and Pain, S. Bradycardia, reversible panconduction defect and syncope following self-medication with a homeopathic medicine. Cardiology 1999;91(4):268-271. PubMed
- Imazio, M., Belli, R., Pomari, F., Cecchi, E., Chinaglia, A., Gaschino, G., Ghisio, A., Trinchero, R., and Brusca, A. Malignant ventricular arrhythmias due to Aconitum napellus seeds. Circulation 12-5-2000;102(23):2907-2908.
- Telang, B. V. and Ng'ang'a, J. N. Involvement of Central adrenergic mechanisms in the induction of cardiac arrhythmias by aconitine nitrate administered intraventricularly. Indian J Physiol Pharmacol. 1975;19(1):1-10.
- Lin, C. C., Chou, H. L., and Lin, J. L. Acute aconitine poisoned patients with ventricular arrhythmias successfully reversed by charcoal hemoperfusion. Am J Emerg.Med 2002;20(1):66-67. PubMed
- Gaibazzi, N., Gelmini, G. P., Montresor, G., Canel, D., Comini, T., Fracalossi, C., Martinetti, C., Poeta, M. L., and Ziacchi, V. [Long QRS tachycardia secondary to Aconitum napellus alkaloid ingestion]. Ital.Heart J.Suppl 2002;3(8):874-877.
- Sorensen, B. [Poisoning with Aconitum napellus (monkshood)]. Ugeskr.Laeger 5-12-2003;165(20):2109-2110.
- Tai, Y. T., Lau, C. P., But, P. P., Fong, P. C., and Li, J. P. Bidirectional tachycardia induced by herbal aconite poisoning. Pacing Clin.Electrophysiol. 1992;15(5):831-839. PubMed
- Agarwal, B. L., Agarwal, R. K., and Misra, D. N. Malignant Arrhythmias Induced by Accidental Aconite Poisoning. Indian Heart J 1977;29(5):246-248.
- Dickens, P., Tai, Y. T., But, P. P., Tomlinson, B., Ng, H. K., and Yan, K. W. Fatal accidental aconitine poisoning following ingestion of Chinese herbal medicine: a report of two cases. Forensic Sci Int 6-28-1994;67(1):55-58. PubMed
- Chan, T. Y., Tomlinson, B., Critchley, J. A., and Cockram, C. S. Herb-induced aconitine poisoning presenting as tetraplegia. Vet.Hum.Toxicol. 1994;36(2):133-134. PubMed
- Chan, T. Y., Tomlinson, B., Chan, W. W., Yeung, V. T., and Tse, L. K. A case of acute aconitine poisoning caused by chuanwu and caowu. J Trop.Med Hyg. 1993;96(1):62-63.
- Yoshioka, N., Gonmori, K., Tagashira, A., Boonhooi, O., Hayashi, M., Saito, Y., and Mizugaki, M. A case of aconitine poisoning with analysis of aconitine alkaloids by GC/SIM. Forensic Sci.Int. 8-15-1996;81(2-3):117-123. PubMed
- Kimura, I., Takada, M., and Nojima, H. Aconitine induces bradycardia through a transmission pathway including the anterior hypothalamus in conscious mice. Biol.Pharm Bull. 1997;20(8):856-860. PubMed
- Chan TY. Aconite poisoning following the percutaneous absorption of Aconitum alkaloids. Forensic Sci Int. 2012 Nov 30;223(1-3):25-7. PubMed
- Chan TY. Aconitum Alkaloid Poisoning Because of Contamination of Herbs by Aconite Roots. Phytother Res. 2016 Jan;30(1):3-8.
- Li H, Liu L, Zhu S, Liu Q. Case reports of aconite poisoning in mainland China from 2004 to 2015: A retrospective analysis. J Forensic Leg Med. 2016 May 25;42:68-73. PubMed
- Zhao D, Wang J, Cui Y, Wu X. Pharmacological effects of Chinese herb aconite (fuzi) on cardiovascular system. J Tradit Chin Med. 2012 Sep;32(3):308-13. PubMed
- Wood C, Coulson J, Thompson J, Bonner S. An intentional aconite overdose: a case report. J Crit Care Med (Targu Mures) 2020;6(2):124-9. PubMed
- Bonanno G, Ippolito M, Moscarelli A, et al. Accidental poisoning with aconitum: case report and review of the literature. Clin Case Rep 2020;8(4):696-8. PubMed
- Blasco Mariño R, Pacheco Reyes A, Canel Micheloud C, Soteras Martínez I. Cardiac Arrest by Aconite Poisoning. Wilderness Environ Med 2021;32(3):415-417. PubMed
- Zhou C, Luo S, Tang J, Quick L, Liu H, Zhao Y. Poisoning Associated with Consumption of a Homemade Medicinal Liquor - Chongqing, China, 2018. MMWR Morb Mortal Wkly Rep 2022;71(16):569-573. PubMed
- Loo G, Yong TH, Yeo C. A case report of bidirectional ventricular tachycardia secondary to aconitum toxicity. J Arrhythm 2022;38(3):451-453. PubMed
- Majumder MI, Mahadi AR, Rahman OU, Roy BK, Shihab HM. Accidental poisoning with aconite overdose: A case report and resuscitative emergency management in a tertiary level hospital of Bangladesh. Clin Case Rep 2023;11(9):e7845. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Ceftolozane Sulfate, Tazobactam Sodium Is Linked to Lower Levels of 7 Nutrients
Natural Medicines records Ceftolozane Sulfate, Tazobactam Sodium as a medicine that can lower these. This is not an interaction with Aconite — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Ceftolozane Sulfate, Tazobactam Sodium nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Aconite and Ceftolozane Sulfate, Tazobactam Sodium Together: Common Questions
Is it safe to take Aconite with Ceftolozane Sulfate, Tazobactam Sodium?
Do Aconite and Ceftolozane Sulfate, Tazobactam Sodium have any of the same side effects?
Are Aconite and Ceftolozane Sulfate, Tazobactam Sodium used for the same thing?
How was the Aconite and Ceftolozane Sulfate, Tazobactam Sodium combination checked?
Does Aconite interact with any other medications?
Does Ceftolozane Sulfate, Tazobactam Sodium interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.