Drug & supplement interaction

Betony + Fludarabine

Fludarabine brand name: Fludara.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Betony and Fludarabine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Betony and Fludarabine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Fludarabine and Betony in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Betony safety at a glance

Betony overall Use caution Generally used in traditional teas, but human safety data are limited, so use with care.
Pregnancy Avoid Traditionally avoided in pregnancy because of possible effects on the uterus; safety is not established.
Breastfeeding Avoid There is not enough safety information, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Fludarabine and Betony? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Fludarabine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Fludarabine is filed under a single classification — oral drugs. Betony has documented interactions with 1 drug class — the most serious being antihypertensive drugs (moderate) — and none of Fludarabine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Betony Does Interact With Other Medications

Betony has 172 moderate known drug interactions in our database — Fludarabine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 172 No known interaction 2,658 (incl. Fludarabine)
Taking anything else?

Check Another of Your Medications Against Betony

Covers the 2,830 medications we’ve checked against Betony. Pick one to open its full report.

What to actually watch for

What Fludarabine’s Own FDA Label Lists

This is not an interaction — none of it involves Betony. These are the most notable effects listed in the ADVERSE REACTIONS section of Fludarabine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Hearing loss Worth acting on
  • A stroke or mini-stroke Worth acting on
  • Bone thinning Worth acting on
  • Pain or burning when passing urine Worth acting on
  • Dehydration Worth acting on
  • Trouble swallowing Worth acting on
  • Bleeding in the gut Worth acting on
  • High potassium Worth acting on
  • A heart attack Worth acting on
  • Blood clots Worth acting on

Showing the 10 most notable of 51 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Fludarabine. Read the label on DailyMed › Betony’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Betony side to compare — that is a limit of the record, not a statement that Betony has no side effects.

Everything else you take

See Every Supplement That Interacts With Fludarabine

This page covers Betony only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Fludarabine page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Fludarabine page

“Someone taking fludarabine (Fludara) for leukemia is often dealing with nausea and digestive trouble at the same time, and that is exactly where this list bites. All 17 supplements and herbs on file interact the same basic way, by changing how much of an oral dose actually gets absorbed, and one of them, activated charcoal, rates major…”

Reviewed by 2 · Jul 18, 2026

Open the Fludarabine interaction page

One more smart check

Taking Betony as Part of a Dietary Supplement Product? Check It for Interactions

We hold 188 real supplement products containing Betony, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Betony. Even though Betony itself has no known interaction with Fludarabine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Betony and Fludarabine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Betony
Top half

#424 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Fludarabine
Steady interest

#1,510 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Betony reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Betony and Fludarabine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Betony

What is Betony?

  • Headaches and tension
  • Anxiety and nervous tension
  • Digestive upset
  • Sore throat and mouth rinse
  • Mild diarrhea

Betony (Stachys officinalis) is a traditional European herb long used for headaches, nervous tension, and digestive complaints. Modern scientific evidence supporting these uses is very limited, and most claims rest on tradition rather than well-designed human studies. Talk with your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Stachys officinalis · Lamiaceae · Aerial parts (leaves, stems, and flowers) · Tea, tincture, dried herb, capsules

An interaction check asks whether these two react with each other — it does not ask whether Betony is a good idea for someone in your situation. Here is what our Betony record says about it on its own.

Betony: dosing

There is no standardized or officially established dose for betony. Traditional use typically involved a tea made from a small amount of the dried herb, but reliable dosing information from clinical studies is not available.If you decide to use a betony product, follow the directions on the product label and do not exceed the recommended amount.

From our Betony monograph — the full record covers uses, side effects and every documented interaction.

Read the full Betony monograph & all interactions
Medication

About Fludarabine Injection

What Is Fludarabine Injection Used For?

Brand name: Fludara

Fludarabine Injection is used to treat adult patients with B-cell chronic lymphocytic leukemia (CLL) — a cancer of the blood and bone marrow — whose disease did not respond to, or got worse during, at least one prior standard chemotherapy regimen containing an alkylating agent.

It is not established as effective for CLL patients who have never been treated or whose disease is not yet refractory (not responding to treatment). Your doctor will determine whether this treatment is appropriate based on your treatment history.

See full Fludarabine Injection drug information
Keep checking

Other Drugs & Betony

Browse every other medication we’ve checked against Betony — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
172Moderate
0Minor
2,657No known interaction
172 Moderate 2,657 No interaction
Moderate

172 interactions

Showing 60 of 172 moderate interactions — see all 172 on the Betony page.

No interaction 2,657 drugs checked — show the list

We also checked Betony against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,657 medications checked with no known interaction — see the full Betony list.

See the full Betony interactions page
See every supplement checked against Fludarabine, ranked by severity
Evidence & sources

Betony References

The 2 references that drive our Betony monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Betony and Fludarabine Together: Common Questions

Is it safe to take Betony with Fludarabine?
We do not list a known interaction between Betony and Fludarabine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Betony and Fludarabine combination checked?
Interactions in our licensed database are recorded against drug classes. Fludarabine is filed under 1 classification, and Betony has documented interactions with 1 drug class — none of Fludarabine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Betony interact with any other medications?
Yes. Betony has 172 documented drug interactions in our database — Fludarabine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Fludarabine interact with any supplements?
Yes. Fludarabine has documented interactions with 17 supplements in our database — Betony is not one of them. The Fludarabine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Betony monograph Uses, safety profile, and every drug interaction in one place Fludarabine Injection drug information The full plain-English guide to this medication Fludarabine supplement interactions Every supplement checked against Fludarabine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Fludarabine and Betony?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.