Drug & supplement interaction

Eyebright + Drospirenone, Ethinyl Estradiol

Drospirenone, Ethinyl Estradiol brand names: Yasmin, Gianvi, Angeliq.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Eyebright and Drospirenone, Ethinyl Estradiol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Eyebright and Drospirenone, Ethinyl Estradiol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Drospirenone, Ethinyl Estradiol and Eyebright in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Eyebright safety at a glance

Eyebright overall Use caution Likely safe in small amounts as a tea, but using homemade or non-sterile preparations directly in the eye is risky.
Pregnancy Avoid Safety has not been established, so it is best avoided during pregnancy.
Breastfeeding Avoid There is not enough safety information, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Drospirenone, Ethinyl Estradiol and Eyebright? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Drospirenone, Ethinyl Estradiol

Interactions in our licensed database are recorded against drug classes, not just single drug names. Drospirenone, Ethinyl Estradiol is filed under 14 classifications — including progesterone, potassium-sparing diuretics, progestin. Eyebright has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Drospirenone, Ethinyl Estradiol’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Eyebright Does Interact With Other Medications

Eyebright has 86 moderate known drug interactions in our database — Drospirenone, Ethinyl Estradiol isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Drospirenone, Ethinyl Estradiol)
Taking anything else?

Check Another of Your Medications Against Eyebright

Covers the 2,830 medications we’ve checked against Eyebright. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Eyebright and Drospirenone, Ethinyl Estradiol May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Headache Additional detail

    Eyebright

    “Orally, eyebright has been reported to cause confusion and headache (4).”

    Eyebright · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

    Drospirenone, Ethinyl Estradiol

    Listed in the ADVERSE REACTIONS section of the FDA label for Drospirenone, Ethinyl Estradiol. Read the label on DailyMed ›

  • Nausea Additional detail

    Eyebright

    “Orally, eyebright has been reported to cause nausea and constipation (4).”

    Eyebright · Natural Medicines adverse-effect record, reported in constipation.

    1 source cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

    Drospirenone, Ethinyl Estradiol

    Listed in the ADVERSE REACTIONS section of the FDA label for Drospirenone, Ethinyl Estradiol. Read the label on DailyMed ›

Reported for Eyebright but not commonly for Drospirenone, Ethinyl Estradiol: a stuffy or runny nose, blurred vision, constipation and confusion.

Effects for Drospirenone, Ethinyl Estradiol come from the ADVERSE REACTIONS section of its FDA label; effects for Eyebright come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Drospirenone, Ethinyl Estradiol

This page covers Eyebright only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Drospirenone, Ethinyl Estradiol page lists 245 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 200 moderate · 39 minor.

From our pharmacist’s overview on the Drospirenone, Ethinyl Estradiol page

“Yasmin and similar drospirenone plus ethinyl estradiol pills only prevent pregnancy while hormone levels stay where they should, so read this list with real care, starting with the six entries rated major out of 245 on file. St.”

Reviewed by 2 · Jul 18, 2026

Open the Drospirenone, Ethinyl Estradiol interaction page

One more smart check

Taking Eyebright as Part of a Dietary Supplement Product? Check It for Interactions

We hold 504 real supplement products containing Eyebright, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Eyebright. Even though Eyebright itself has no known interaction with Drospirenone, Ethinyl Estradiol, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Eyebright and Drospirenone, Ethinyl Estradiol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Eyebright
Top half

#370 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Drospirenone, Ethinyl Estradiol
Top 25%

#477 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Eyebright reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Eyebright and Drospirenone, Ethinyl Estradiol records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Eyebright

What is Eyebright?

Eyebright
  • Eye irritation and redness
  • Conjunctivitis (pink eye)
  • Eye strain
  • Allergy and cold-related eye symptoms
  • Nasal congestion and hay fever

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. There is not enough reliable evidence to confirm it works, and using non-sterile herbal preparations in the eye carries a real risk of infection, so talk to your pharmacist or doctor before trying it.

Euphrasia officinalis · Orobanchaceae · Aerial parts (leaves, stems, and flowers) · Tea, eye drops, tincture, capsules, homeopathic preparations, compresses

An interaction check asks whether these two react with each other — it does not ask whether Eyebright is a good idea for someone in your situation. Here is what our Eyebright record says about it on its own.

Eyebright: dosing

There is no standardized or well-established dose for eyebright. Traditional use as a tea typically involves steeping the dried herb in hot water, but amounts vary widely between products and sources.If you choose to use a commercial eyebright product, follow the directions on the label and choose products from reputable manufacturers. For anything used in or near the eye, only use products that are specifically made and labeled as sterile eye preparations.

From our Eyebright monograph — the full record covers uses, side effects and every documented interaction.

Read the full Eyebright monograph & all interactions
Keep checking

Other Drugs & Eyebright

Browse every other medication we’ve checked against Eyebright — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Eyebright page.

No interaction 2,743 drugs checked — show the list

We also checked Eyebright against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Eyebright list.

See the full Eyebright interactions page
See every supplement checked against Drospirenone, Ethinyl Estradiol, ranked by severity
Evidence & sources

Eyebright References

The 4 references that drive our Eyebright monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  4. Porchezhian, E., Ansari, S. H., and Shreedharan, N. K. Antihyperglycemic activity of Euphrasia officinale leaves. Fitoterapia 2000;71(5):522-526. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Eyebright and Drospirenone, Ethinyl Estradiol Together: Common Questions

Is it safe to take Eyebright with Drospirenone, Ethinyl Estradiol?
We do not list a known interaction between Eyebright and Drospirenone, Ethinyl Estradiol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Eyebright and Drospirenone, Ethinyl Estradiol have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Eyebright and Drospirenone, Ethinyl Estradiol combination checked?
Interactions in our licensed database are recorded against drug classes. Drospirenone, Ethinyl Estradiol is filed under 14 classifications, and Eyebright has documented interactions with 1 drug class — none of Drospirenone, Ethinyl Estradiol's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Eyebright interact with any other medications?
Yes. Eyebright has 86 documented drug interactions in our database — Drospirenone, Ethinyl Estradiol is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Drospirenone, Ethinyl Estradiol interact with any supplements?
Yes. Drospirenone, Ethinyl Estradiol has documented interactions with 245 supplements in our database — Eyebright is not one of them. The Drospirenone, Ethinyl Estradiol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Eyebright monograph Uses, safety profile, and every drug interaction in one place Drospirenone, Ethinyl Estradiol supplement interactions Every supplement checked against Drospirenone, Ethinyl Estradiol, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Drospirenone, Ethinyl Estradiol and Eyebright?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.