Drug & supplement interaction

Figwort + Ramelteon

Ramelteon brand name: Rozerem.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Figwort and Ramelteon in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Figwort and Ramelteon

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ramelteon and Figwort in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Figwort safety at a glance

Figwort overall Use caution Limited safety data exist, so use with care and short-term only.
Pregnancy Avoid Not enough safety information; best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data, so it is best to avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ramelteon and Figwort? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Ramelteon

Interactions in our licensed database are recorded against drug classes, not just single drug names. Ramelteon is filed under 6 classifications — including cytochrome p450 2c9 (cyp2c9) substrates, cytochrome p450 1a2 (cyp1a2) substrates, cytochrome p450 1a2 (cyp1a2) substrates. Figwort has documented interactions with 2 drug classes — the most serious being diuretic drugs (moderate) and lithium (moderate) — and none of Ramelteon’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Figwort Does Interact With Other Medications

Figwort has 76 moderate known drug interactions in our database — Ramelteon isn’t one of them. If you take anything else, check it against the full list below.

Moderate 76 No known interaction 2,754 (incl. Ramelteon)
Taking anything else?

Check Another of Your Medications Against Figwort

Covers the 2,830 medications we’ve checked against Figwort. Pick one to open its full report.

What to actually watch for

What Ramelteon’s Own FDA Label Lists

This is not an interaction — none of it involves Figwort. These are the most notable effects listed in the ADVERSE REACTIONS section of Ramelteon’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both.

  • Trouble sleeping mentioned in 16.9% of FDA reports for Ramelteon
  • Drowsiness mentioned in 5.7% of FDA reports for Ramelteon
  • Tiredness mentioned in 3.9% of FDA reports for Ramelteon
  • Dizziness mentioned in 3.7% of FDA reports for Ramelteon
  • Nausea mentioned in 4.6% of FDA reports for Ramelteon
  • Headache

From the ADVERSE REACTIONS section of the FDA label for Ramelteon. Read the label on DailyMed › Where a percentage is shown, it is the share of 7,279 voluntary FDA FAERS reports for Ramelteon that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Figwort’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Figwort side to compare — that is a limit of the record, not a statement that Figwort has no side effects.

From our Q&A

Questions About Figwort or Ramelteon

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Figwort or Ramelteon, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Ramelteon

This page covers Figwort only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ramelteon page lists 228 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Grapefruit (major).

By severity: 9 major · 173 moderate · 46 minor.

From our pharmacist’s overview on the Ramelteon page

“Ramelteon (Rozerem) is a prescription sleep aid, and its 228 interacting supplements call for real care, starting with the nine rated major. The frustrating part is that the things sleepless people typically reach for, kava, CBD, a glass of wine before bed, sit at the heart of the problem.”

Reviewed by 2 · Jul 18, 2026

Open the Ramelteon interaction page

One more smart check

Taking Figwort as Part of a Dietary Supplement Product? Check It for Interactions

We hold 147 real supplement products containing Figwort, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Figwort. Even though Figwort itself has no known interaction with Ramelteon, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Figwort and Ramelteon Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Figwort
Top half

#535 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ramelteon
Top 25%

#587 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Figwort reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Figwort and Ramelteon records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Figwort

What is Figwort?

  • Skin conditions like eczema and psoriasis
  • Minor wounds and rashes
  • Swelling and inflammation
  • Mild constipation
  • Traditional 'detox' or lymphatic support

Figwort is a traditional herb used mainly for skin problems and minor swelling, but solid human studies are lacking, so its benefits remain unproven. It is generally used short-term and topically, and people with heart conditions, pregnant women, and nursing mothers should avoid it until more is known.

Scrophularia nodosa · Scrophulariaceae · Aerial parts (leaves, stems, flowers) and sometimes the root · Tea, tincture, capsules, dried herb, topical creams or ointments

An interaction check asks whether these two react with each other — it does not ask whether Figwort is a good idea for someone in your situation. Here is what our Figwort record says about it on its own.

Figwort: dosing

There is no established standardized dose for figwort. Traditional use varies by the form (tea, tincture, capsule, or ointment) and by the product maker. Avoid using more than the label suggests, and do not use it for long periods without professional advice.

From our Figwort monograph — the full record covers uses, side effects and every documented interaction.

Read the full Figwort monograph & all interactions
Medication

About Ramelteon

What Is Ramelteon Used For?

Brand name: Rozerem

Ramelteon tablets — sold as the brand Rozerem and as generic ramelteon — are used to treat insomnia when the main problem is trouble falling asleep at the start of the night. It is not indicated for difficulty staying asleep.

Clinical studies supporting its effectiveness ran up to six months in both adults and elderly patients.

Most-Reported Side Effects for Ramelteon

From FAERS, the FDA’s public side-effect reporting system (7,348 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Initial insomnia 446 reports
Somnolence 418 reports
Insomnia 400 reports
Middle insomnia 390 reports
Nausea 337 reports
See full Ramelteon drug information
Keep checking

Other Drugs & Figwort

Browse every other medication we’ve checked against Figwort — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
76Moderate
0Minor
2,753No known interaction
76 Moderate 2,753 No interaction
Moderate

76 interactions

Showing 60 of 76 moderate interactions — see all 76 on the Figwort page.

No interaction 2,753 drugs checked — show the list

We also checked Figwort against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,753 medications checked with no known interaction — see the full Figwort list.

See the full Figwort interactions page
See every supplement checked against Ramelteon, ranked by severity
Evidence & sources

Figwort References

The 1 references that drive our Figwort monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Figwort and Ramelteon Together: Common Questions

Is it safe to take Figwort with Ramelteon?
We do not list a known interaction between Figwort and Ramelteon. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Figwort and Ramelteon combination checked?
Interactions in our licensed database are recorded against drug classes. Ramelteon is filed under 6 classifications, and Figwort has documented interactions with 2 drug classes — none of Ramelteon's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Figwort interact with any other medications?
Yes. Figwort has 76 documented drug interactions in our database — Ramelteon is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Ramelteon interact with any supplements?
Yes. Ramelteon has documented interactions with 228 supplements in our database — Figwort is not one of them. The Ramelteon interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Figwort monograph Uses, safety profile, and every drug interaction in one place Ramelteon drug information The full plain-English guide to this medication Ramelteon supplement interactions Every supplement checked against Ramelteon, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Ramelteon and Figwort?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.