Drug & supplement interaction

Marsh Labrador Tea + Loxapine

Loxapine brand names: Loxitane, Adasuve.

Moderate Interaction
Medically reviewed by · Updated September 2026
The bottom line Moderate

Marsh Labrador Tea has a moderate interaction with Loxapine. Marsh Labrador tea can potentiate effects of barbiturates and alcohol.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Marsh Labrador Tea and Loxapine

Here is the interaction we found between these two, with the evidence behind it.

Moderate

CNS DEPRESSANTS

Why this applies to Loxapine

Loxapine falls under CNS DEPRESSANTS — the group Marsh Labrador Tea interacts with.

Marsh Labrador tea can potentiate effects of barbiturates and alcohol.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the simple version: Loxapine is a sedating antipsychotic, so it can already make you drowsy, slow your thinking, and leave you feeling foggy. Marsh Labrador tea has been noted to deepen the calming, sleepy effects of things like alcohol and barbiturates. The worry is that pairing it with Loxapine could stack those effects, leaving you more sedated, dizzy, or unsteady than usual, which raises the risk of falls or trouble concentrating.

I want to be honest about the strength of this, though. It's a theoretical concern based on how the plant behaves, not solid human studies. On top of that, this tea contains grayanotoxins that can be genuinely toxic, so I wouldn't recommend it regardless. Please run it by your pharmacist or doctor before mixing the two.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Marsh Labrador Tea Also Interacts With Other Medications

Marsh Labrador Tea has 247 moderate known drug interactions in our database — the Loxapine one above is one of them. If you take anything else, check it against the full list below.

Moderate 247 No known interaction 2,583 (incl. Loxapine)
Taking anything else?

Check Another of Your Medications Against Marsh Labrador Tea

Covers the 2,830 medications we’ve checked against Marsh Labrador Tea. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Loxapine

This page covers Marsh Labrador Tea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Loxapine page lists 123 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Henbane (major).

By severity: 11 major · 95 moderate · 17 minor.

From our pharmacist’s overview on the Loxapine page

“Loxapine (Loxitane, Adasuve) treats schizophrenia, and it causes drowsiness on its own, which is why 78 of the 123 supplement and herbal ingredients on this page deepen that sedation, at the extreme to the point of slowed breathing. Alcohol is the clearest example, with beer and wine both rated major on solid human evidence, and kava s…”

Reviewed by 2 · Jul 18, 2026

Open the Loxapine interaction page

How much people look this up

Where Marsh Labrador Tea and Loxapine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Marsh Labrador Tea
Steady interest

#1,132 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Loxapine
Steady interest

#2,021 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Marsh Labrador Tea

What is Marsh Labrador Tea?

Marsh Labrador Tea
  • Colds and respiratory complaints
  • Cough and congestion
  • Mild aches and joint discomfort
  • Topical relief of skin irritation, swelling, and insect bites
  • Traditional use as a diuretic

Marsh Labrador tea is a bog-growing shrub used in folk medicine for coughs, colds, and skin problems, but high-quality human evidence for any use is lacking. Because it contains grayanotoxins (andromedotoxin) that can be poisonous, it is not considered safe for routine use, and pregnant or breastfeeding people should avoid it.

Read the full Marsh Labrador Tea monograph & all interactions
Medication

About Loxapine

What Is Loxapine Used For?

Brand names: Loxitane, Adasuve

Loxapine capsules are used for the ongoing treatment of schizophrenia in adults. Adasuve (loxapine inhalation powder) is used in a different, more specific situation: to quickly calm sudden, severe agitation in adults with schizophrenia or bipolar I disorder. Because of serious safety requirements, Adasuve must be given by a healthcare professional in a certified medical setting — it is not a take-home medication.

See full Loxapine drug information
Keep checking

Other Drugs & Marsh Labrador Tea

Browse every other medication we’ve checked against Marsh Labrador Tea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
247Moderate
0Minor
2,582No known interaction
247 Moderate 2,582 No interaction
Moderate

247 interactions

Showing 60 of 247 moderate interactions — see all 247 on the Marsh Labrador Tea page.

No interaction 2,582 drugs checked — show the list

We also checked Marsh Labrador Tea against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,582 medications checked with no known interaction — see the full Marsh Labrador Tea list.

See the full Marsh Labrador Tea interactions page
See every supplement checked against Loxapine, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Marsh Labrador Tea monograph › Uses, safety, and every drug interaction in one place Loxapine supplement interactions › Every supplement checked against Loxapine, ranked by severity Loxapine drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Marsh Labrador Tea and Loxapine Together: Common Questions

Can you take Marsh Labrador Tea with Loxapine?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Marsh Labrador Tea and Loxapine interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Loxapine and Marsh Labrador Tea?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.