Drug & supplement interaction

Marsh Labrador Tea + Morphine Sulfate

Morphine Sulfate brand names: MS Contin, Kadian, Avinza, Morphabond, Arymo ER.

Moderate Interaction
The bottom line Moderate

Marsh Labrador Tea has a moderate interaction with Morphine Sulfate. Marsh Labrador tea can potentiate effects of barbiturates and alcohol.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Marsh Labrador Tea and Morphine Sulfate

Here is the interaction we found between these two, with the evidence behind it.

Moderate

CNS DEPRESSANTS

Why this applies to Morphine Sulfate

Morphine Sulfate falls under CNS DEPRESSANTS — the group Marsh Labrador Tea interacts with.

Marsh Labrador tea can potentiate effects of barbiturates and alcohol.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the basic idea with this pairing. Marsh Labrador tea has been noted to deepen the calming, sedating effects of things that slow down your brain, like alcohol and barbiturates. Morphine sits in that same camp of central nervous system depressants. So in theory, combining the two could leave you more drowsy, foggy, dizzy, or unsteady than morphine alone, and in a worst case it could weigh on your breathing.

I'll be honest with you though: this is a theoretical concern based on how these substances act, not something proven in solid human studies. Morphine isn't a prodrug, so this isn't about changing how your body activates it, it's just two sedating things stacking up. Since morphine is already a powerful medicine, I'd skip the marsh Labrador tea (which carries its own toxicity risks) and check with your pharmacist or doctor first.

References
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Marsh Labrador Tea Also Interacts With Other Medications

Marsh Labrador Tea has 247 moderate known drug interactions in our database — the Morphine Sulfate one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Marsh Labrador Tea

Covers the 2,830 medications we’ve checked against Marsh Labrador Tea. Pick one to open its full report.

From our Q&A

Questions About Marsh Labrador Tea or Morphine Sulfate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Marsh Labrador Tea or Morphine Sulfate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Morphine Sulfate

This page covers Marsh Labrador Tea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Morphine Sulfate page lists 172 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 8 major · 138 moderate · 26 minor.

From our pharmacist’s overview on the Morphine Sulfate page

“With morphine sulfate (MS Contin, Kadian, Avinza), an opioid powerful enough to slow breathing on its own, this list warrants genuine respect. Of the 172 supplements and foods on file, 8 carry a major rating, and most of those pile extra sedation onto a drug that already sedates.”

Reviewed by 2 · Jul 18, 2026

Open the Morphine Sulfate interaction page

How much people look this up

Where Marsh Labrador Tea and Morphine Sulfate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Marsh Labrador Tea
Steady interest

#1,132 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Morphine Sulfate
Steady interest

#1,606 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Marsh Labrador Tea

What is Marsh Labrador Tea?

Marsh Labrador Tea
  • Colds and respiratory complaints
  • Cough and congestion
  • Mild aches and joint discomfort
  • Topical relief of skin irritation, swelling, and insect bites
  • Traditional use as a diuretic

Marsh Labrador tea is a bog-growing shrub used in folk medicine for coughs, colds, and skin problems, but high-quality human evidence for any use is lacking. Because it contains grayanotoxins (andromedotoxin) that can be poisonous, it is not considered safe for routine use, and pregnant or breastfeeding people should avoid it.

Read the full Marsh Labrador Tea monograph & all interactions
Medication

About Morphine

What Is Morphine Used For?

Brand names: MS Contin, Kadian, Avinza, Morphabond, Arymo ER

Morphine is used to manage acute (short-term) and chronic (long-term) pain that is severe enough to need an opioid and that hasn't been adequately treated by other options. The higher-concentration liquid form is reserved for adults who are already opioid-tolerant — meaning their body is used to opioid medications.

Because of real risks of addiction, misuse, and overdose, morphine is only prescribed when other pain treatments have not worked or are not expected to work. It is not intended for long-term use unless the pain continues to be severe and no alternatives are suitable.

See full Morphine drug information
Keep checking

Other Drugs & Marsh Labrador Tea

Browse every other medication we’ve checked against Marsh Labrador Tea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
247Moderate
0Minor
2,582No known interaction
Moderate

247 interactions

Showing 60 of 247 moderate interactions — see all 247 on the Marsh Labrador Tea page.

No interaction 2,582 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Marsh Labrador Tea and Morphine Sulfate Together: Common Questions

Can you take Marsh Labrador Tea with Morphine Sulfate?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Marsh Labrador Tea and Morphine Sulfate interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.