Drug & supplement interaction

Marsh Labrador Tea + Palovarotene

Palovarotene brand name: Sohonos.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 27, 2026
The bottom line No known interaction

We found no known interaction between Marsh Labrador Tea and Palovarotene in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Palovarotene states a food rule worth keeping to.

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Interaction report

Marsh Labrador Tea and Palovarotene

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Palovarotene and Marsh Labrador Tea in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Marsh Labrador Tea safety at a glance

Marsh Labrador Tea overall Use caution The plant contains toxic grayanotoxins, so any internal use carries a risk of poisoning.
Pregnancy Likely Unsafe When used orally; avoid using. Marsh Labrador tea is considered to be a potential uterine stimulant and abortifacient. Read the full pregnancy detail
Breastfeeding Avoid Not enough safety data and it contains potentially toxic substances, so avoid use.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Palovarotene and Marsh Labrador Tea? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Palovarotene

Interactions in our licensed database are recorded against drug classes, not just single drug names. Palovarotene is filed under 2 classifications — cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Marsh Labrador Tea has documented interactions with 1 drug class — the most serious being cns depressants (moderate) — and none of Palovarotene’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Marsh Labrador Tea Does Interact With Other Medications

Marsh Labrador Tea has 248 moderate known drug interactions in our database — Palovarotene isn’t one of them. If you take anything else, check it against the full list below.

Moderate 248 No known interaction 2,582 (incl. Palovarotene)
Taking anything else?

Check Another of Your Medications Against Marsh Labrador Tea

Covers the 2,830 medications we’ve checked against Marsh Labrador Tea. Pick one to open its full report.

What to actually watch for

What Marsh Labrador Tea Itself Has Been Linked To

This is not an interaction — nothing below involves Palovarotene. It is the side-effect record for Marsh Labrador Tea on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Marsh Labrador Tea, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Seizures Worth acting on Additional detail

    “Orally, large amounts of marsh Labrador tea can cause poisoning due to its ledol constituent (2). The essential oil of marsh Labrador tea can cause severe irritation of the gastrointestinal tract, vomiting, diarrhea, irritation and damage to the kidneys and urinary tract, heavy perspiration, myalgias, and arthralgias.”

    Marsh Labrador Tea · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 97164. Dampc A, Luczkiewicz M. Bog Labrador tea--the aromatic beverage and spice: a review of origin, processing and safety. J Sci Food Agric. 2015;95(8):1577-83. PubMed

    “Orally, ledol, a constituent of marsh Labrador tea essential oil, can cause central nervous system excitation in a dose-dependent manner. Small amounts of ledol can lead to mild stimulating effects similar to caffeine, while larger doses can lead to spasms, seizures, paralysis, and even death.”

    Marsh Labrador Tea · Natural Medicines adverse-effect record, reported in epilepsy.

    1 source cited
    1. 97164. Dampc A, Luczkiewicz M. Bog Labrador tea--the aromatic beverage and spice: a review of origin, processing and safety. J Sci Food Agric. 2015;95(8):1577-83. PubMed
  • Sweating Additional detail

    Recorded for Marsh Labrador Tea in the same Natural Medicines adverse-effect record shown under Seizures above.

  • Diarrhea / Vomiting Additional detail

    “Orally, ledol, a constituent of the essential oil of marsh Labrador tea, can cause gastrointestinal irritation resulting in vomiting, gastroenteritis, and diarrhea.”

    Marsh Labrador Tea · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 97164. Dampc A, Luczkiewicz M. Bog Labrador tea--the aromatic beverage and spice: a review of origin, processing and safety. J Sci Food Agric. 2015;95(8):1577-83. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Marsh Labrador Tea — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Palovarotene’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Palovarotene column appears here.

Special populations

Marsh Labrador Tea in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally; avoid using. Marsh Labrador tea is considered to be a potential uterine stimulant and abortifacient.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Palovarotene Products Have a Food Rule — Marsh Labrador Tea Should Not Break It

At least one FDA label for a product containing Palovarotene says to take it with food. If you take Marsh Labrador Tea on an empty stomach out of habit, keep them separate — and take Palovarotene with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Palovarotene products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Refer to Table 1 in Full Prescribing Information for complete pediatric dosing ( 2.2 ) Take SOHONOS with food preferably at same time each day ( 2.3 ).

From the Dosage and Administration section of the FDA label we read for Palovarotene — where that label names a specific product, the instruction is that product's. See the Palovarotene drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Palovarotene

This page covers Marsh Labrador Tea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Palovarotene page lists 138 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 94 moderate · 41 minor.

From our pharmacist’s overview on the Palovarotene page

“Palovarotene (Sohonos) treats fibrodysplasia ossificans progressiva, a rare disease where soft tissue gradually turns to bone, and because it is cleared almost entirely by one liver enzyme, CYP3A4, supplement choices genuinely matter here. Three of the 138 ingredients on record rate major: grapefruit can drive palovarotene levels and i…”

Reviewed by 2 · Jul 18, 2026

Open the Palovarotene interaction page

How much people look this up

Where Marsh Labrador Tea and Palovarotene Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Marsh Labrador Tea
Steady interest

#1,022 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Palovarotene
Steady interest

#1,791 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Marsh Labrador Tea reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Marsh Labrador Tea and Palovarotene records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Marsh Labrador Tea

What is Marsh Labrador Tea?

Marsh Labrador Tea
  • Colds and respiratory complaints
  • Cough and congestion
  • Mild aches and joint discomfort
  • Topical relief of skin irritation, swelling, and insect bites
  • Traditional use as a diuretic

Marsh Labrador tea is a bog-growing shrub used in folk medicine for coughs, colds, and skin problems, but high-quality human evidence for any use is lacking. Because it contains grayanotoxins (andromedotoxin) that can be poisonous, it is not considered safe for routine use, and pregnant or breastfeeding people should avoid it.

Rhododendron tomentosum · Ericaceae · Leaves and flowering twigs (and an essential oil distilled from them) · Tea (infusion), essential oil, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Marsh Labrador Tea is a good idea for someone in your situation. Here is what our Marsh Labrador Tea record says about it on its own.

Marsh Labrador Tea: dosing

There is no established safe or standardized dose for Marsh Labrador tea. Because the plant naturally contains toxic grayanotoxins, even traditional preparations carry risk, and stronger or longer brews increase that risk.If you choose to use a commercial product, follow the directions on the label exactly and do not exceed them. Never assume that "natural" means harmless.

From our Marsh Labrador Tea monograph — the full record covers uses, side effects and every documented interaction.

Read the full Marsh Labrador Tea monograph & all interactions
Medication

About Palovarotene

What Is Palovarotene Used For?

Brand name: Sohonos

Palovarotene (brand name Sohonos) is used to reduce the volume of new heterotopic ossification, which is bone growing where it shouldn't, in people with fibrodysplasia ossificans progressiva (FOP).

It is approved for adults and for children aged 8 years and older for females and 10 years and older for males.

Most-Reported Side Effects for Palovarotene

From FAERS, the FDA’s public side-effect reporting system (57 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dry skin 13 reports
Pruritus 10 reports
Skin exfoliation 9 reports
Alopecia 5 reports
Cross sensitivity reaction 4 reports
See full Palovarotene drug information
Keep checking

Other Drugs & Marsh Labrador Tea

Browse every other medication we’ve checked against Marsh Labrador Tea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
248Moderate
0Minor
2,581No known interaction
248 Moderate 2,581 No interaction
Moderate

248 interactions

Showing 60 of 248 moderate interactions — see all 248 on the Marsh Labrador Tea page.

No interaction 2,581 drugs checked — show the list

We also checked Marsh Labrador Tea against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,581 medications checked with no known interaction — see the full Marsh Labrador Tea list.

See the full Marsh Labrador Tea interactions page
See every supplement checked against Palovarotene, ranked by severity
Evidence & sources

Marsh Labrador Tea References

The 3 references that drive our Marsh Labrador Tea monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Dampc A, Luczkiewicz M. Bog Labrador tea--the aromatic beverage and spice: a review of origin, processing and safety. J Sci Food Agric. 2015;95(8):1577-83. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Marsh Labrador Tea and Palovarotene Together: Common Questions

Is it safe to take Marsh Labrador Tea with Palovarotene?
We do not list a known interaction between Marsh Labrador Tea and Palovarotene. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Marsh Labrador Tea and Palovarotene at the same time of day?
At least one FDA label for a product containing Palovarotene says to take it with food. If you take Marsh Labrador Tea on an empty stomach out of habit, keep them separate and take Palovarotene with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Palovarotene products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Marsh Labrador Tea and Palovarotene combination checked?
Interactions in our licensed database are recorded against drug classes. Palovarotene is filed under 2 classifications, and Marsh Labrador Tea has documented interactions with 1 drug class — none of Palovarotene's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Marsh Labrador Tea interact with any other medications?
Yes. Marsh Labrador Tea has 248 documented drug interactions in our database — Palovarotene is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Palovarotene interact with any supplements?
Yes. Palovarotene has documented interactions with 138 supplements in our database — Marsh Labrador Tea is not one of them. The Palovarotene interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Marsh Labrador Tea monograph Uses, safety profile, and every drug interaction in one place Palovarotene drug information The full plain-English guide to this medication Palovarotene supplement interactions Every supplement checked against Palovarotene, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Palovarotene and Marsh Labrador Tea?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.