Drug & supplement interaction

Marsh Labrador Tea + Voxelotor

Voxelotor brand name: Oxbryta.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Marsh Labrador Tea and Voxelotor in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Marsh Labrador Tea and Voxelotor

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Voxelotor and Marsh Labrador Tea in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Marsh Labrador Tea safety at a glance

Marsh Labrador Tea overall Use caution The plant contains toxic grayanotoxins, so any internal use carries a risk of poisoning.
Pregnancy Likely Unsafe When used orally; avoid using. Marsh Labrador tea is considered to be a potential uterine stimulant and abortifacient. Read the full pregnancy detail
Breastfeeding Avoid Not enough safety data and it contains potentially toxic substances, so avoid use.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Voxelotor and Marsh Labrador Tea? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Voxelotor

Interactions in our licensed database are recorded against drug classes, not just single drug names. Voxelotor is filed under 3 classifications — cytochrome p450 3a4 (cyp3a4) inhibitors, cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Marsh Labrador Tea has documented interactions with 1 drug class — the most serious being cns depressants (moderate) — and none of Voxelotor’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Marsh Labrador Tea Does Interact With Other Medications

Marsh Labrador Tea has 248 moderate known drug interactions in our database — Voxelotor isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Marsh Labrador Tea

Covers the 2,830 medications we’ve checked against Marsh Labrador Tea. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Marsh Labrador Tea and Voxelotor May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Diarrhea reported in 14.3% of FDA reports for Voxelotor Additional detail

    Marsh Labrador Tea

    “Orally, large amounts of marsh Labrador tea can cause poisoning due to its ledol constituent (2). The essential oil of marsh Labrador tea can cause severe irritation of the gastrointestinal tract, vomiting, diarrhea, irritation and damage to the kidneys and urinary tract, heavy perspiration, myalgias, and arthralgias.”

    Marsh Labrador Tea · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 97164. Dampc A, Luczkiewicz M. Bog Labrador tea--the aromatic beverage and spice: a review of origin, processing and safety. J Sci Food Agric. 2015;95(8):1577-83. PubMed

    “Orally, ledol, a constituent of the essential oil of marsh Labrador tea, can cause gastrointestinal irritation resulting in vomiting, gastroenteritis, and diarrhea.”

    Marsh Labrador Tea · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 97164. Dampc A, Luczkiewicz M. Bog Labrador tea--the aromatic beverage and spice: a review of origin, processing and safety. J Sci Food Agric. 2015;95(8):1577-83. PubMed

    Voxelotor

    Listed in the ADVERSE REACTIONS section of the FDA label for Voxelotor, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Reported for Marsh Labrador Tea but not commonly for Voxelotor: sweating, vomiting and seizures.

Effects for Voxelotor come from the ADVERSE REACTIONS section of its FDA label; effects for Marsh Labrador Tea come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 22,291 voluntary FDA FAERS reports for Voxelotor that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Marsh Labrador Tea in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally; avoid using. Marsh Labrador tea is considered to be a potential uterine stimulant and abortifacient.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Voxelotor

This page covers Marsh Labrador Tea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Voxelotor page lists 143 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 100 moderate · 40 minor.

From our pharmacist’s overview on the Voxelotor page

“Anyone taking voxelotor (Oxbryta) for sickle cell disease should treat this list with real care, because the pattern behind it is unusually consistent. Almost every entry works through CYP3A4, the same liver enzyme that clears voxelotor, so these ingredients can push the drug's blood level higher or pull it lower, either adding side ef…”

Reviewed by 2 · Jul 18, 2026

Open the Voxelotor interaction page

How much people look this up

Where Marsh Labrador Tea and Voxelotor Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Marsh Labrador Tea
Steady interest

#1,267 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Voxelotor
Steady interest

#2,247 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Marsh Labrador Tea reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Marsh Labrador Tea and Voxelotor records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Marsh Labrador Tea

What is Marsh Labrador Tea?

Marsh Labrador Tea
  • Colds and respiratory complaints
  • Cough and congestion
  • Mild aches and joint discomfort
  • Topical relief of skin irritation, swelling, and insect bites
  • Traditional use as a diuretic

Marsh Labrador tea is a bog-growing shrub used in folk medicine for coughs, colds, and skin problems, but high-quality human evidence for any use is lacking. Because it contains grayanotoxins (andromedotoxin) that can be poisonous, it is not considered safe for routine use, and pregnant or breastfeeding people should avoid it.

Rhododendron tomentosum · Ericaceae · Leaves and flowering twigs (and an essential oil distilled from them) · Tea (infusion), essential oil, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Marsh Labrador Tea is a good idea for someone in your situation. Here is what our Marsh Labrador Tea record says about it on its own.

Marsh Labrador Tea: dosing

There is no established safe or standardized dose for Marsh Labrador tea. Because the plant naturally contains toxic grayanotoxins, even traditional preparations carry risk, and stronger or longer brews increase that risk.If you choose to use a commercial product, follow the directions on the label exactly and do not exceed them. Never assume that "natural" means harmless.

From our Marsh Labrador Tea monograph — the full record covers uses, side effects and every documented interaction.

Read the full Marsh Labrador Tea monograph & all interactions
Medication

About Voxelotor

What Is Voxelotor Used For?

Brand name: Oxbryta

Oxbryta (voxelotor) is approved to treat sickle cell disease (SCD) in adults and in children as young as 4 years old. It works by targeting the underlying problem in sickle cell disease — the abnormal hemoglobin that causes red blood cells to take on a rigid, sickle shape.

This approval was granted under the FDA's accelerated approval pathway, based on the drug's ability to raise hemoglobin levels. Continued approval may depend on results from confirmatory clinical trials showing broader clinical benefit.

Most-Reported Side Effects for Voxelotor

From FAERS, the FDA’s public side-effect reporting system (22,300 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Sickle cell anaemia with crisis 11,218 reports
Diarrhea 3,187 reports
Nausea 2,016 reports
Headache 1,691 reports
Abdominal pain upper 1,171 reports
See full Voxelotor drug information
Keep checking

Other Drugs & Marsh Labrador Tea

Browse every other medication we’ve checked against Marsh Labrador Tea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
248Moderate
0Minor
2,581No known interaction
Moderate

248 interactions

Showing 60 of 248 moderate interactions — see all 248 on the Marsh Labrador Tea page.

No interaction 2,581 drugs checked — show the list
Evidence & sources

Marsh Labrador Tea References

The 3 references that drive our Marsh Labrador Tea monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Dampc A, Luczkiewicz M. Bog Labrador tea--the aromatic beverage and spice: a review of origin, processing and safety. J Sci Food Agric. 2015;95(8):1577-83. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Marsh Labrador Tea and Voxelotor Together: Common Questions

Is it safe to take Marsh Labrador Tea with Voxelotor?
We do not list a known interaction between Marsh Labrador Tea and Voxelotor. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Marsh Labrador Tea and Voxelotor have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Marsh Labrador Tea and Voxelotor combination checked?
Interactions in our licensed database are recorded against drug classes. Voxelotor is filed under 3 classifications, and Marsh Labrador Tea has documented interactions with 1 drug class — none of Voxelotor's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Marsh Labrador Tea interact with any other medications?
Yes. Marsh Labrador Tea has 248 documented drug interactions in our database — Voxelotor is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Voxelotor interact with any supplements?
Yes. Voxelotor has documented interactions with 143 supplements in our database — Marsh Labrador Tea is not one of them. The Voxelotor interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Voxelotor and Marsh Labrador Tea?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.