Drug & supplement interaction

Padang Cassia + Amphetamine

Amphetamine brand names: Dyanavel XR, Adensys XR-ODT, Mydayis, Adzenys ER.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Padang Cassia and Amphetamine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Padang Cassia and Amphetamine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Amphetamine and Padang Cassia in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Padang Cassia safety at a glance

Padang Cassia overall Use caution Generally safe as a food spice, but cassia cinnamons contain coumarin that may harm the liver in large or long-term supplement doses.
Pregnancy Use caution Food amounts are likely fine, but avoid concentrated supplement doses during pregnancy without medical advice.
Breastfeeding Use caution Food amounts are likely fine, but there is little safety data on supplement-level doses while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Amphetamine and Padang Cassia? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Amphetamine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Amphetamine is filed under 6 classifications — including monoamine oxidase inhibitors (maois), amphetamines, stimulant drugs. Padang Cassia has documented interactions with 3 drug classes — the most serious being antidiabetes drugs (moderate), cytochrome p450 3a4 (cyp3a4) substrates (moderate) and hepatotoxic drugs (moderate) — and none of Amphetamine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Padang Cassia Does Interact With Other Medications

Padang Cassia has 934 moderate known drug interactions in our database — Amphetamine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 934 No known interaction 1,896 (incl. Amphetamine)
Taking anything else?

Check Another of Your Medications Against Padang Cassia

Covers the 2,830 medications we’ve checked against Padang Cassia. Pick one to open its full report.

What to actually watch for

What Padang Cassia Itself Has Been Linked To

This is not an interaction — nothing below involves Amphetamine. It is the side-effect record for Padang Cassia on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Padang Cassia, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Liver problems Worth acting on Additional detail

    “Orally, Padang cassia appears to be well tolerated. No adverse effects have been reported in clinical trials when Padang cassia is used alone. When Padang cassia extract is used with banaba leaf extract in a specific combination product (Inlacin, Dexa Medica), adverse effects reported in clinical trials have included dizziness, headache, tremor, palpitations, weakness, diaphoresis, and stomach upset.”

    Padang Cassia · Natural Medicines adverse-effect record, reported in cirrhosis.

    6 sources cited
    1. 93117. Kort DH, Lobo RA. Preliminary evidence that cinnamon improves menstrual cyclicity in women with polycystic ovary syndrome: a randomized controlled trial. Am J Obstet Gynecol 2014;211(5):487.e1-6. PubMed
    2. 93147. Ziegenfuss TN, Hofheins JE, Mendel RW, et al. Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women. J Int Soc Sports Nutr 2006;3:45-53. PubMed
    3. 92848. Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89. PubMed
    4. 92849. Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Comple
    5. 93121. Wang R, Wang R, Yan B. Extraction of essential oils from five cinnamon leaves and identification of their volatile compound compositions. Innovative Food Science and Emerging Technologies 2009;10:289-92. DOI
    6. 93122. Wang YH, Avula B, Nanayakkara NP, et al. Cassia cinnamon as a source of coumarin in cinnamon-flavored food and food supplements in the United States. J Agric Food Chem 2013;61(18):4470-6. PubMed

    “Padang cassia contains coumarin. There is some concern that ingesting large amounts of Padang cassia might cause hepatotoxicity in some people due to its coumarin content. In otherwise healthy humans, very high doses of coumarin, from 50-7000 mg daily, can result in hepatotoxicity that resolves when coumarin use is discontinued.”

    Padang Cassia · Natural Medicines adverse-effect record, reported in cirrhosis.

    6 sources cited
    1. 93121. Wang R, Wang R, Yan B. Extraction of essential oils from five cinnamon leaves and identification of their volatile compound compositions. Innovative Food Science and Emerging Technologies 2009;10:289-92. DOI
    2. 93122. Wang YH, Avula B, Nanayakkara NP, et al. Cassia cinnamon as a source of coumarin in cinnamon-flavored food and food supplements in the United States. J Agric Food Chem 2013;61(18):4470-6. PubMed
    3. 93123. Woehrlin F, Fry H, Abraham K, Preiss-Weigert A. Quantification of flavoring constituents in cinnamon: high variation of coumarin in cassia bark from the German retail market and in authentic samples from Indonesia. J Agric Food Chem 2010;58(19):10568-75. PubMed
    4. 15302. Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
    5. 93147. Ziegenfuss TN, Hofheins JE, Mendel RW, et al. Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women. J Int Soc Sports Nutr 2006;3:45-53. PubMed
    6. 108268. Shishehbor F, Rezaeyan Safar M, Rajaei E, Haghighizadeh MH. Cinnamon consumption improves clinical symptoms and inflammatory markers in women with rheumatoid arthritis. J. Am. Coll. Nutr. 2018. PubMed
  • Tremor or shakiness / Dizziness / Headache Additional detail

    “Orally, a specific product containing extracts of Padang cassia and banaba leaf (Inlacin, Dexa Medica) has been reported to cause dizziness, headache, tremor, and weakness. However, it is unclear if these adverse effects were caused by Padang cassia extract, banaba leaf extract, or the combination.”

    Padang Cassia · Natural Medicines adverse-effect record, reported in cluster headache.

    2 sources cited
    1. 92848. Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89. PubMed
    2. 92849. Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Comple
  • Sweating / A fast or pounding heartbeat / Stomach upset Additional detail

    Recorded for Padang Cassia in the same Natural Medicines adverse-effect record shown under Liver problems above.

Everything above comes from the Natural Medicines adverse-effect record for Padang Cassia — expand a row for the licensed statement it rests on. We haven’t matched Amphetamine to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Amphetamine.

Overlapping uses

What Amphetamine Is Prescribed For, and What Padang Cassia Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Amphetamine is a prescription medicine with approved uses on its FDA label. Padang Cassia is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Amphetamine is prescribed for: Amphetamine treats Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years and older. Adzenys XR-ODT, Dyanavel XR, and the amphetamine extended-release orally disintegrating tablet formulations are specifically approved for ADHD in this age group. Amphetamine Sulfate tablets and Evekeo (amphetamine sulfate tablets) are also approved for narcolepsy (a sleep disorder causing uncontrollable daytime sleepiness) and as a short-term aid in a calorie-restricted weight-loss program for exogenous obesity (weight gain from external factors like overeating) in patients who have not responded to other approaches.

Padang Cassia has been studied for:

  • Obesity studied, not established Padang Cassia has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Padang Cassia for obesity

    Preliminary clinical research in overweight or obese adults with metabolic syndrome shows that taking a specific Padang cassia extract (Cinnulin PF, Integrity Nutraceuticals International) 250 mg twice daily for 12 weeks increases lean body mass by 1.4 kg and decreases body fat percentage by 1% when compared with placebo.

    2 sources cited
    1. 93118. Roussel AM, Hininger I, Benaraba R, et al. Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese. J Am Coll Nutr 2009;28(1):16-21. PubMed
    2. 93147. Ziegenfuss TN, Hofheins JE, Mendel RW, et al. Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women. J Int Soc Sports Nutr 2006;3:45-53. PubMed

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Amphetamine on your own; if you are taking Padang Cassia for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Padang Cassia or Amphetamine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Padang Cassia or Amphetamine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Amphetamine

This page covers Padang Cassia only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Amphetamine page lists 130 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Bitter Orange (major), Brewer's Yeast (major) and Cowhage (major).

By severity: 16 major · 97 moderate · 17 minor.

From our pharmacist’s overview on the Amphetamine page

“Amphetamine (Dyanavel XR, Adzenys ER, Mydayis) is a prescription stimulant, usually taken for ADHD, and its interaction list is one to approach with genuine care. Of the 130 supplements and herbal ingredients on file, 16 carry a major rating, and many of those work the same way, either inhibiting monoamine oxidase, as yohimbe does, or…”

Reviewed by 2 · Jul 18, 2026

Open the Amphetamine interaction page

How much people look this up

Where Padang Cassia and Amphetamine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Padang Cassia
Top half

#510 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Amphetamine
Top 5%

#42 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Padang Cassia reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Padang Cassia and Amphetamine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Padang Cassia

What is Padang Cassia?

  • Adding flavor to food
  • Digestive upset
  • Blood sugar support
  • Antimicrobial purposes
  • Antioxidant support

Padang Cassia is a type of cinnamon (Indonesian or Korintje cinnamon) grown mainly in Indonesia and used widely as a kitchen spice. As a supplement, evidence for health benefits like blood sugar control is limited and mixed, and like other cassia cinnamons it naturally contains coumarin, which can be harmful to the liver in large amounts. Use food amounts freely, but talk to a pharmacist or doctor before taking concentrated cinnamon supplements.

Cinnamomum burmannii · Lauraceae · Inner bark (and bark-derived essential oil) · Ground spice, dried bark sticks (quills), capsules, powder, extract, essential oil, tea

An interaction check asks whether these two react with each other — it does not ask whether Padang Cassia is a good idea for someone in your situation. Here is what our Padang Cassia record says about it on its own.

Padang Cassia: dosing

There is no official, standardized dose of Padang Cassia for any health condition. Amounts used in studies vary widely and are not specific to this species.If you choose to use a cinnamon supplement, follow the directions on the product label and do not exceed the recommended amount. Because cassia cinnamons are higher in coumarin, it is wise to keep concentrated supplement doses low and to avoid taking them every day for long periods.Using Padang Cassia as a normal cooking spice is a low-risk way to enjoy it.

From our Padang Cassia monograph — the full record covers uses, side effects and every documented interaction.

Read the full Padang Cassia monograph & all interactions
Medication

About Amphetamine

What Is Amphetamine Used For?

Brand names: Dyanavel XR, Adensys XR-ODT, Mydayis, Adzenys ER

Amphetamine treats Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years and older. Adzenys XR-ODT, Dyanavel XR, and the amphetamine extended-release orally disintegrating tablet formulations are specifically approved for ADHD in this age group.

Amphetamine Sulfate tablets and Evekeo (amphetamine sulfate tablets) are also approved for narcolepsy (a sleep disorder causing uncontrollable daytime sleepiness) and as a short-term aid in a calorie-restricted weight-loss program for exogenous obesity (weight gain from external factors like overeating) in patients who have not responded to other approaches.

See full Amphetamine drug information
Keep checking

Other Drugs & Padang Cassia

Browse every other medication we’ve checked against Padang Cassia — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
934Moderate
0Minor
1,895No known interaction
934 Moderate 1,895 No interaction
Moderate

934 interactions

Showing 60 of 934 moderate interactions — see all 934 on the Padang Cassia page.

No interaction 1,895 drugs checked — show the list

We also checked Padang Cassia against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 1,895 medications checked with no known interaction — see the full Padang Cassia list.

See the full Padang Cassia interactions page
See every supplement checked against Amphetamine, ranked by severity
Evidence & sources

Padang Cassia References

The 14 references that drive our Padang Cassia monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
  2. Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
  3. Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
  4. Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89. PubMed
  5. Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Comple
  6. Kort DH, Lobo RA. Preliminary evidence that cinnamon improves menstrual cyclicity in women with polycystic ovary syndrome: a randomized controlled trial. Am J Obstet Gynecol 2014;211(5):487.e1-6. PubMed
  7. Roussel AM, Hininger I, Benaraba R, et al. Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese. J Am Coll Nutr 2009;28(1):16-21. PubMed
  8. Wang R, Wang R, Yan B. Extraction of essential oils from five cinnamon leaves and identification of their volatile compound compositions. Innovative Food Science and Emerging Technologies 2009;10:289-92. DOI
  9. Wang YH, Avula B, Nanayakkara NP, et al. Cassia cinnamon as a source of coumarin in cinnamon-flavored food and food supplements in the United States. J Agric Food Chem 2013;61(18):4470-6. PubMed
  10. Woehrlin F, Fry H, Abraham K, Preiss-Weigert A. Quantification of flavoring constituents in cinnamon: high variation of coumarin in cassia bark from the German retail market and in authentic samples from Indonesia. J Agric Food Chem 2010;58(19):10568-75. PubMed
  11. Subehan S, Kadota S, Tezuka Y. In vitro mechanism-based inactivation of cytochrome P450 3A4 by a new constituent of Cinnamomum burmani. Planta Med 2008;74(12):1474-80.
  12. Bernardo MA, Silva ML, Santos E, et al. Effect of cinnamon tea on postprandial glucose concentration. J Diabetes Res 2015;2015:913651. PubMed
  13. Ziegenfuss TN, Hofheins JE, Mendel RW, et al. Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women. J Int Soc Sports Nutr 2006;3:45-53. PubMed
  14. Shishehbor F, Rezaeyan Safar M, Rajaei E, Haghighizadeh MH. Cinnamon consumption improves clinical symptoms and inflammatory markers in women with rheumatoid arthritis. J. Am. Coll. Nutr. 2018. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Padang Cassia and Amphetamine Together: Common Questions

Is it safe to take Padang Cassia with Amphetamine?
We do not list a known interaction between Padang Cassia and Amphetamine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Padang Cassia and Amphetamine used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Padang Cassia in each. That is a conversation for your prescriber, especially if Amphetamine is being adjusted to a target.
How was the Padang Cassia and Amphetamine combination checked?
Interactions in our licensed database are recorded against drug classes. Amphetamine is filed under 6 classifications, and Padang Cassia has documented interactions with 3 drug classes — none of Amphetamine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Padang Cassia interact with any other medications?
Yes. Padang Cassia has 934 documented drug interactions in our database — Amphetamine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Amphetamine interact with any supplements?
Yes. Amphetamine has documented interactions with 130 supplements in our database — Padang Cassia is not one of them. The Amphetamine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Padang Cassia monograph Uses, safety profile, and every drug interaction in one place Amphetamine drug information The full plain-English guide to this medication Amphetamine supplement interactions Every supplement checked against Amphetamine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 14 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Amphetamine and Padang Cassia?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.