Drug & supplement interaction

Sweet Woodruff + Dexmedetomidine

Dexmedetomidine brand names: Precedex, Igalmi.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Sweet Woodruff and Dexmedetomidine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Sweet Woodruff and Dexmedetomidine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dexmedetomidine and Sweet Woodruff in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Sweet Woodruff safety at a glance

Sweet Woodruff overall Use caution Generally used in small amounts as a flavoring, but its coumarin content can be harmful in larger or long-term doses.
Pregnancy Avoid Not enough safety data and possible coumarin-related risks, so it is best avoided.
Breastfeeding Avoid Safety is unknown, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dexmedetomidine and Sweet Woodruff? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Dexmedetomidine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Dexmedetomidine is filed under 3 classifications — qt interval-prolonging drugs, cns depressants, oral drugs. Sweet Woodruff has documented interactions with 1 drug class — the most serious being anticoagulant/antiplatelet drugs (moderate) — and none of Dexmedetomidine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Sweet Woodruff Does Interact With Other Medications

Sweet Woodruff has 122 moderate known drug interactions in our database — Dexmedetomidine isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Sweet Woodruff

Covers the 2,830 medications we’ve checked against Sweet Woodruff. Pick one to open its full report.

What to actually watch for

What Sweet Woodruff Itself Has Been Linked To

This is not an interaction — nothing below involves Dexmedetomidine. It is the side-effect record for Sweet Woodruff on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Sweet Woodruff, this list is the first place to look.

  • Dizziness Additional detail

    “Orally, sweet woodruff can cause headache, stupor, or dizziness, especially in larger amounts (12,18,76951).”

    Sweet Woodruff · Natural Medicines adverse-effect record, reported in cluster headache.

    3 sources cited
    1. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
    2. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    3. 76951. Stuart, M. The Encyclopedia of Herbs and Herbalism. 1979.
  • Headache Additional detail

    “Orally, sweet woodruff is generally well tolerated. However, a thorough evaluation of safety outcomes has not been conducted.

    Most Common Adverse Effects:

    Orally: Headache.

    Serious Adverse Effects (Rare):

    Orally: Liver disease.”

    Sweet Woodruff · Natural Medicines adverse-effect record, reported in cirrhosis.

Everything above comes from the Natural Medicines adverse-effect record for Sweet Woodruff — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Dexmedetomidine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Dexmedetomidine column appears here.

Everything else you take

See Every Supplement That Interacts With Dexmedetomidine

This page covers Sweet Woodruff only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dexmedetomidine page lists 108 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), American Hellebore (major), Arsenic (major) and Beer (major).

By severity: 13 major · 80 moderate · 15 minor.

From our pharmacist’s overview on the Dexmedetomidine page

“Dexmedetomidine (Precedex, Igalmi) is itself a sedative, used for procedural sedation and to calm acute agitation, so the 108 supplements and herbs on this list deserve real vigilance rather than a shrug. Most of them, 78 in all, deepen its sedative effect; the major entries here include alcohol and kava, which can push ordinary drowsi…”

Reviewed by 2 · Jul 18, 2026

Open the Dexmedetomidine interaction page

One more smart check

Taking Sweet Woodruff as Part of a Dietary Supplement Product? Check It for Interactions

We hold 27 real supplement products containing Sweet Woodruff, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Sweet Woodruff. Even though Sweet Woodruff itself has no known interaction with Dexmedetomidine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Sweet Woodruff and Dexmedetomidine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Sweet Woodruff
Top half

#580 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dexmedetomidine
Top half

#1,049 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Sweet Woodruff reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Sweet Woodruff and Dexmedetomidine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Sweet Woodruff

What is Sweet Woodruff?

Sweet Woodruff
  • Digestive upset
  • Anxiety, restlessness, and sleep
  • Liver and gallbladder complaints
  • Urinary tract problems
  • Respiratory complaints
  • As a flavoring agent

Sweet woodruff is a fragrant European herb traditionally used for digestion, calming, and various other complaints, but solid human evidence for any of these uses is lacking. It contains coumarin, which can be harmful in large amounts, so it should be used only sparingly and avoided during pregnancy and breastfeeding. Talk to your pharmacist or doctor before using it.

Galium odoratum · Rubiaceae · Above-ground parts (leaves, flowering tops, and stems) · Dried herb, tea, tinctures, and traditional flavoring (for example in some wines and beverages)

An interaction check asks whether these two react with each other — it does not ask whether Sweet Woodruff is a good idea for someone in your situation. Here is what our Sweet Woodruff record says about it on its own.

Sweet Woodruff: dosing

There is no well-established, standardized medicinal dose for sweet woodruff, and good clinical research is lacking. Because of its coumarin content, experts generally recommend keeping any use to small amounts and short periods of time.If you choose to use a product that contains sweet woodruff, follow the directions on the label and do not exceed the recommended amount.

From our Sweet Woodruff monograph — the full record covers uses, side effects and every documented interaction.

Read the full Sweet Woodruff monograph & all interactions
Medication

About Dexmedetomidine

Most-Reported Side Effects for Dexmedetomidine

From FAERS, the FDA’s public side-effect reporting system (6,304 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Bradycardia 471 reports
Hypotension 378 reports
Cardiac arrest 312 reports
Agitation 230 reports
Respiratory failure 210 reports
Keep checking

Other Drugs & Sweet Woodruff

Browse every other medication we’ve checked against Sweet Woodruff — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
122Moderate
0Minor
2,707No known interaction
Moderate

122 interactions

Showing 60 of 122 moderate interactions — see all 122 on the Sweet Woodruff page.

No interaction 2,707 drugs checked — show the list
Evidence & sources

Sweet Woodruff References

The 6 references that drive our Sweet Woodruff monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Sulma, T. and Wierzchowska, K. [Studies on the content of coumarin in the herbs of the woodruff (Herba Asperulae odoratae) throughout the vegetative period of the plant.]. Acta Pol.Pharm 1963;20:77-82.
  4. Kovac-Besovic, E. E. and Duric, K. Thin layer chromatography-application in qualitative analysis on presence of coumarins and flavonoids in plant material. Bosn.J Basic Med.Sci. 2003;3(3):19-26. PubMed
  5. Stuart, M. The Encyclopedia of Herbs and Herbalism. 1979.
  6. Kahkeshani N, Farahanikia B, Mahdaviani P, et al. Antioxidant and burn healing potential of Galium odoratum extracts. Res Pharm Sci 2013;8(3):197-203.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Sweet Woodruff and Dexmedetomidine Together: Common Questions

Is it safe to take Sweet Woodruff with Dexmedetomidine?
We do not list a known interaction between Sweet Woodruff and Dexmedetomidine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Sweet Woodruff and Dexmedetomidine combination checked?
Interactions in our licensed database are recorded against drug classes. Dexmedetomidine is filed under 3 classifications, and Sweet Woodruff has documented interactions with 1 drug class — none of Dexmedetomidine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Sweet Woodruff interact with any other medications?
Yes. Sweet Woodruff has 122 documented drug interactions in our database — Dexmedetomidine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Dexmedetomidine interact with any supplements?
Yes. Dexmedetomidine has documented interactions with 108 supplements in our database — Sweet Woodruff is not one of them. The Dexmedetomidine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Dexmedetomidine and Sweet Woodruff?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.