Medication interaction hub

What Supplements Interact with Candesartan Cilexetil?

Candesartan Cilexetil brand names: Atacand, Amias. Every interaction below applies to the brands too.

138 Interactions 4 Major 112 Moderate 22 Minor
Curated & coded by · Clinical Pharmacist · Updated September 17, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Candesartan Cilexetil? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Candesartan Cilexetil against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line

138 supplements and herbal ingredients have interactions with Candesartan Cilexetil on file in the HelloPharmacist interaction database — 4 rated major, 112 moderate, and 22 minor. The most serious involve American Hellebore, Tyramine, Activated Charcoal and American Mistletoe.

Our assessment: with 4 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Candesartan Cilexetil.

Major 4 Moderate 112 Minor 22 No known interaction 1,314

Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Candesartan Cilexetil: Top Interactions at a Glance

The Candesartan Cilexetil supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 138 interacting ingredients — plus 1,314 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Candesartan Cilexetil Combinations Today

The Candesartan Cilexetil + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Ashwagandha + Candesartan Cilexetili

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.

Read the full interaction Moderate Likelihood Possible Nattokinase + Candesartan Cilexetili

Theoretically, nattokinase might increase the risk of hypotension when used with antihypertensive drugs.

Read the full interaction Moderate Likelihood Probable Celery + Candesartan Cilexetili

Theoretically, celery seed extract might have additive effects with antihypertensive drugs.

Read the full interaction Moderate Likelihood Possible Berberine + Candesartan Cilexetili

Theoretically, berberine might have additive effects with antihypertensive drugs.

Read the full interaction Moderate Likelihood Possible Licorice + Candesartan Cilexetili

Theoretically, licorice might reduce the effects of antihypertensive drugs.

Read the full interaction Moderate Likelihood Possible Theanine + Candesartan Cilexetili

Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.

Read the full interaction
The complete list

Every Supplement Checked Against Candesartan Cilexetil

All 1,452 ingredients in our database, ranked by severity — 138 with a Candesartan Cilexetil interaction on file and 1,314 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Candesartan Cilexetil?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Ashwagandha with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.

Full Ashwagandha + Candesartan Cilexetil answer

Can you take Nattokinase with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, nattokinase might increase the risk of hypotension when used with antihypertensive drugs.

Full Nattokinase + Candesartan Cilexetil answer

Can you take Celery with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, celery seed extract might have additive effects with antihypertensive drugs.

Full Celery + Candesartan Cilexetil answer

Can you take Berberine with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, berberine might have additive effects with antihypertensive drugs.

Full Berberine + Candesartan Cilexetil answer

Can you take Licorice with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, licorice might reduce the effects of antihypertensive drugs.

Full Licorice + Candesartan Cilexetil answer

Can you take Wine with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use may interfere with blood pressure control.

Full Wine + Candesartan Cilexetil answer

Can you take Yohimbe with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, yohimbe might reduce the effects of antihypertensive drugs.

Full Yohimbe + Candesartan Cilexetil answer

Can you take Adrafinil with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, adrafinil might reduce the effects of antihypertensive drugs.

Full Adrafinil + Candesartan Cilexetil answer

Can you take Agmatine with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.

Full Agmatine + Candesartan Cilexetil answer

Can you take Algal Oil with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.

Full Algal Oil + Candesartan Cilexetil answer

Can you take Andrographis with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.

Full Andrographis + Candesartan Cilexetil answer

Can you take Artichoke with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, artichoke leaf extract may increase the risk of hypotension when taken with antihypertensive drugs.

Full Artichoke + Candesartan Cilexetil answer

Can you take Asafoetida with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from animal research suggests that asafoetida has hypotensive effects.

Full Asafoetida + Candesartan Cilexetil answer

Can you take Ash with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of ash seed with antihypertensive drugs might have additive blood pressure lowering effects.

Full Ash + Candesartan Cilexetil answer

Can you take Baikal Skullcap with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of Baikal skullcap with antihypertensive drugs might have additive effects and increase the risk of hypotensi...

Full Baikal Skullcap + Candesartan Cilexetil answer

Can you take Basil with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, basil might increase the risk of hypotension when taken with antihypertensive drugs.

Full Basil + Candesartan Cilexetil answer

Can you take Beta-glucans with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.

Full Beta-glucans + Candesartan Cilexetil answer

Can you take Betony with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, betony might have additive effects with blood pressure lowering drugs due to hypotensive activity of the glycosides found in...

Full Betony + Candesartan Cilexetil answer

Can you take Black Seed with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking black seed with antihypertensive drugs might increase the risk of hypotension.

Full Black Seed + Candesartan Cilexetil answer

Can you take Blue Cohosh with Candesartan Cilexetil?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Constituents in blue cohosh might increase blood pressure by causing coronary vasoconstriction.

Full Blue Cohosh + Candesartan Cilexetil answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Candesartan Cilexetil is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Candesartan Cilexetil, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Candesartan Cilexetil sits in 3 interaction categories. Open any one to see what the group means:

Antihypertensive Drugs 119 ingredients

Blood-pressure-lowering medications. Supplements that lower (or raise) blood pressure can amplify or fight these drugs.

119 of the supplement ingredients on this page reach Candesartan Cilexetil through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Candesartan Cilexetil through this category.

Angiotensin Receptor Blockers (Arbs) 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Candesartan Cilexetil through this category.

About Candesartan Cilexetil

Candesartan is an angiotensin II receptor antagonist used to treat high blood pressure and congestive heart failure.

Generic name: Candesartan Cilexetil  ·  Brand names: Atacand, Amias.

See the full Candesartan drug information

Related: does Candesartan Cilexetil deplete any nutrients?

Candesartan Cilexetil has 2 reported nutrient associations in the research literature — see the Candesartan Cilexetil nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Candesartan Cilexetil

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Candesartan Cilexetil.

Search a supplement product

Type a product name, brand, or UPC — smart search across our full catalog.

Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

Or scan the bottle

Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.

Open the label scanner

Prefer typing? The interaction checker looks up products by name too.

Products that contain Candesartan Cilexetil-interacting ingredients

Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Candesartan Cilexetil.

TNT Thermanite by GEC Genetic Edge Compounds contains Tyramine Diablos ECA Fire Caps by Innovative Laboratories contains Tyramine Ultimate Burn by Schwartz Laboratories contains Tyramine Final Cutz by Infinite Labs contains Tyramine
Pharmacist Counseling Corner

Candesartan Cilexetil & Supplements: Common Questions

What supplements interact with Candesartan Cilexetil?
More than you might expect — 138 in total, though they are far from equal: 4 are rated major, 112 moderate, and 22 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: American Hellebore, Tyramine, Activated Charcoal.
Which Candesartan Cilexetil supplement interactions are the most serious?
Focus on the major group: American Hellebore, Tyramine, Activated Charcoal and American Mistletoe. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Candesartan Cilexetil?
Usually yes — most people on Candesartan Cilexetil can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Atacand have the same supplement interactions as Candesartan Cilexetil?
Yes — Atacand, Amias all contain Candesartan Cilexetil, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Candesartan Cilexetil deplete any vitamins or nutrients?
It might — Candesartan Cilexetil has 2 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Candesartan Cilexetil nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Candesartan Cilexetil and my other medications?
This page covers Candesartan Cilexetil against supplements and herbal ingredients. Checking Candesartan Cilexetil against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Candesartan drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

More Free Pharmacist Tools

Supplement interaction checker Check any supplement or product against your medications Supplement label scanner Photograph a Supplement Facts panel; we check every ingredient Browse medications A–Z Every drug we’ve checked against herbs & supplements Ingredient directory Every vitamin, herb & mineral we track, with interaction data Product directory Look up any bottle by name, brand, or barcode Ask a pharmacist Free, personal answer from our licensed team
Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 17, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.