Major interaction on record — check this product against your medications before combining. Based on 4 of 7 ingredients. Check your meds →
Dietary supplement

Amino Multi Complex Ingredients & Drug Interactions

by New Sun

Amino Multi Complex label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Amino Multi Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Amino Multi Complex is a dietary supplement by New Sun with 7 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 526 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin B6, Whey Protein Isolate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Amino Multi Complex by New Sun

Ask about any prescription or over-the-counter medication and we check it for interactions with Amino Multi Complex by New Sun — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Amino Multi Complex by New Sun

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 8 active ingredients.
  • “Amino Acids” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Blend of Peptide-Bound Amino Acid Sources” is a proprietary blend — the label gives one combined amount (1.50 Gram(s)) without saying how much of each component you get.

This product contains 8 ingredients, of which 5 are active amino acids and proteins: L-glutamine (an amino acid), vitamin B6 (a B vitamin), whey protein isolate, L-arginine, L-ornithine, sodium caseinate (milk protein), and soy protein isolate. The inactive ingredients are gelatin, cellulose, stearic acid, magnesium stearate, and silica—these are binders and fillers that hold the capsule together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Sideroblastic anemia — rated "Effective" (Vitamin B6) (Natural Medicines).
  • On file: Sickle cell disease — rated "Effective" (Glutamine) (Natural Medicines).
  • On file: Vitamin B6 deficiency — rated "Effective" (Vitamin B6) (Natural Medicines).
  • On file: Pyridoxine-dependent epilepsy — rated "Effective" (Vitamin B6) (Natural Medicines).
  • On file: Hyperhomocysteinemia — rated "Likely Effective" (Vitamin B6) (Natural Medicines).

The evidence for these ingredients varies by use. L-glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness.

Vitamin B6 is effective for sideroblastic anemia, vitamin B6 deficiency, and a rare seizure condition; it's possibly effective for morning sickness and likely effective for high homocysteine levels. Whey protein is possibly effective for athletic performance but possibly ineffective for osteoporosis and COPD; evidence is insufficient for cognitive decline and HIV wasting.

L-ornithine is possibly effective for athletic performance but evidence is insufficient for dry skin, insomnia, and gum disease. We hold insufficient evidence for sodium caseinate and soy protein isolate across their listed uses, and gelatin appears possibly ineffective for diarrhea with insufficient evidence for other claims.

The evidence, ingredient by ingredient Vitamin B6 Whey Protein Casein Protein Gelatin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated but people with kidney or liver disease should use it only under medical supervision; pregnancy is likely safe, but there isn't enough data for breastfeeding. Common side effects include bloating, constipation, diarrhea, nausea, and headache; high doses (10–30 grams daily) increase GI upset.

Vitamin B6 is safe at normal food and supplement doses but high doses over time can damage nerves (sensory neuropathy); pregnancy guidance exists but data for breastfeeding isn't on file. Whey protein is generally well tolerated but may trigger or worsen acne, and concentrated supplements aren't well studied—talk to your doctor before high-dose use.

Pregnancy and breastfeeding data aren't on file. L-arginine is often well tolerated short-term but can lower blood pressure and isn't safe for everyone; safety data for pregnancy and breastfeeding are insufficient.

L-ornithine is well tolerated short-term but long-term safety isn't well studied; avoid during pregnancy and breastfeeding. Sodium caseinate is generally safe as a food protein but concentrated supplements should be discussed with your doctor first.

Gelatin is widely eaten and considered safe; talk to your doctor before supplement doses. Rare allergic reactions (including anaphylaxis) have been reported with casein and gelatin.

Side effects, ingredient by ingredient Vitamin B6 Whey Protein Casein Protein Gelatin

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 7 matched ingredients can interact with medications — Whey Protein, L-arginine, Glutamine, Vitamin B6.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications; Parkinson's medications.
  • For scale: 526 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check with your pharmacist before taking this product if you use levodopa for Parkinson's disease (Major risk of reduced effectiveness), anticonvulsants like phenytoin or phenobarbital, blood pressure medications including ACE inhibitors or ARBs, blood thinners or antiplatelet drugs, quinolone or tetracycline antibiotics, bisphosphonates for bone health, amiodarone for heart rhythm, potassium-sparing diuretics, diabetes medications, or sildenafil (Viagra). No interactions are documented for the inactive ingredients or for soy protein isolate, which we could not check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

This amino acid and protein blend may help with athletic performance or recovery if you don't take medications for Parkinson's disease, seizures, high blood pressure, or blood clotting. If you're on any prescription medications—especially levodopa, anticonvulsants, blood pressure drugs, blood thinners, or diabetes medicine—talk with your pharmacist before starting.

Check your exact medications with the tool on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Amino Multi Complex, straight from the product label.

Brand New Sun
Barcode (UPC) 71-1
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2019
DSLD ID 202929
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Amino Multi Complex by New Sun, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
71-1
IngredientAmount% DV
Calories10 Calorie(s)--
L-Glutamine0 NP--
Vitamin B66.5 mg325%
Whey Protein Isolate0 NP--
L-Arginine0 NP--
Protein2 Gram(s)3%
L-Ornithine0 NP--
Sodium Caseinate0 NP--
Gelatin0 NP--
Amino Acids0 NP--
Soy Protein isolate0 NP--
Blend of Peptide-Bound Amino Acid Sources1.5 Gram(s)--

Other ingredients: Gelatin, Cellulose, Stearic Acid, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommendation: As a dietary supplement, take two capsules three times daily with meals, preferably with juice.

Precautions

Keep out of reach of children.

Do not use if safety seal is missing or broken.

Warning: If pregnant, nursing, taking any medications, or experiencing health issues, consult your doctor before use.

Allergen Information: Contains milk and soy.

Storage

Store in a cool, dry place.

General Statements

Typical Amino Acid Profile (example)(per serving) Essential Amino Acids Amount per 2 capsule serving L-Histindine 18mg, L-Isoleucine 57mg, L-Leucine 102mg, L-Lysine 92mg, L-Methionine 17mg, L-Phenylalanine 36mg, L-Threonine 70mg, L-Tryptophan 18mg, L-Valine 70mg Non-Essential Amino Acids L-Alanine 67mg, L-Arginine 153mg, L-Aspartic Acid 123mg, L-Cysteine 19mg, L-Glutamic Acid 227mg, L-Glutamine 100mg, Glycine 83mg, L-Hydroxyproline 22mg, L-Ornithine 12mg, L-Proline 89mg, L-Serine 53mg, L-Tyrosine 33mg subject to natural variability.

FDA Statement of Identity

Dietary Supplement

Formula

Allergen Information: Contains milk and soy.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Amino Multi Complex by New Sun label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Amino Multi Complex label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Amino Multi Complex by New Sun

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B6

Interacts with
210 drugs
6.5 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Protein

2 Gram(s) per serving

Blend of Peptide-Bound Amino Acid Sources

1.5 Gram(s) per serving

Other (inactive) ingredients: Gelatin, Cellulose, Stearic Acid, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Amino Multi Complex by New Sun Drug Interactions

Want to check YOUR meds against Amino Multi Complex?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
526Drugs
5 Major 513 Moderate 8 Minor

Ingredients driving the most interactions

Vitamin B6 210
Whey Protein Isolate 53

Individual Drug Interactions

The ingredients in Amino Multi Complex interact with 526 drugs. Click any drug to see the details.

2 of the 7 ingredients in Amino Multi Complex interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6 Whey Protein Isolate

Each ingredient & the kinds of drugs it affects

For each ingredient in Amino Multi Complex with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

Whey Protein Isolate4 drug types · 53 drugs

Levodopa

Theoretically, whey protein might decrease levodopa absorption.
Small clinical studies show that concomitant ingestion of protein or high doses of leucine or isoleucine (100 mg/kg) and levodopa can exacerbate tremor, rigidity, and the "on-off" syndrome in patients with Parkinson disease.

Likelihood Probable Evidence D
Bisphosphonates

Theoretically, whey protein might reduce the absorption of bisphosphonates.
Whey protein contains minerals such as calcium that bind bisphosphonates in the gut. Advise patients to take bisphosphonates at least 30 minutes before whey protein, but preferably at a different time of day.

Likelihood Probable Evidence D
Quinolone Antibiotics

Theoretically, whey protein might decrease quinolone absorption.
Whey protein contains minerals, such as calcium, that can bind to quinolones in the gut. To avoid this interaction, advise patients to take oral quinolones at least 2 hours before or 4-6 hours after whey protein.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, whey protein might decrease tetracycline absorption.
Whey protein contains minerals, such as calcium, that bind to tetracyclines in the gut. To avoid this interaction, advise patients to take oral tetracyclines at least 2 hours before or 4-6 hours after whey protein.

Likelihood Probable Evidence D
Whey Protein Isolate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Amino Multi Complex, from the product label.

New Sun

See all New Sun products
Name
New Sun, Inc.
City
Hendersonville
State
NC
ZipCode
28792
Phone Number
(800) 544-0777
Web Address
mynewsun.com
Pharmacist Counseling Corner

Amino Multi Complex by New Sun: Common Questions

Does Amino Multi Complex by New Sun interact with any medications?
Yes. Based on its ingredients, Amino Multi Complex has a known interaction with 526 medications, including 5 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Amino Multi Complex contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while pregnant?
L-glutamine is likely safe in pregnancy. For the other active ingredients—vitamin B6, whey protein, L-arginine, L-ornithine, sodium caseinate, and soy protein isolate—we either don't have pregnancy data on file or the data advises against use. Talk with your doctor or pharmacist before taking this product if you're pregnant or planning to become pregnant.
Can I take this while breastfeeding?
We don't have sufficient safety data for most ingredients while breastfeeding. L-glutamine and vitamin B6 have some caution noted but aren't recommended without medical advice. Talk with your doctor or pharmacist before using this supplement if you're breastfeeding.
What's whey protein isolate and what does it do?
Whey protein isolate is a concentrated form of milk protein. It's possibly effective for athletic performance but evidence suggests it's possibly ineffective for bone health and lung disease. It's generally well tolerated, though it may trigger acne in some people.
Will this help my athletic performance?
Whey protein isolate and L-ornithine are both possibly effective for athletic performance according to the research we have. Other ingredients in this blend don't have established evidence for this use.
What are the most common side effects I might feel?
Bloating, constipation, diarrhea, nausea, headache, and belching are the most commonly reported side effects, mostly from L-glutamine and gelatin. Most are dose-related and tend to improve at lower doses.
Is there anything in this I should avoid if I have a milk allergy?
Yes—this product contains whey protein isolate and sodium caseinate, both milk proteins. If you're allergic to milk, avoid this product entirely, as it can cause allergic reactions ranging from skin rashes to anaphylaxis.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Amino Multi Complex is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Amino Multi Complex label
Go deeper

The Full Monographs Behind Amino Multi Complex’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Whey Protein

Interacts with 53 drugs

Whey protein is a high-quality, complete protein made from cow's milk that can help people meet protein needs and support muscle growth when combined with exercise. It is generally safe for...

Read the full Whey Protein monograph → Herb & supplement monograph

Casein Protein

Casein is a slow-digesting protein from milk that supplies all the essential amino acids and is popular for muscle recovery, especially overnight. It is generally safe for most people who to...

Read the full Casein Protein monograph → Herb & supplement monograph

Gelatin

Gelatin is a protein made from animal collagen, used as a food, a capsule ingredient, and a supplement for joint, skin, and bone health. For most health uses, the evidence is limited or mixe...

Read the full Gelatin monograph →
Sources

Sources & How We Checked

Amino Multi Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 207 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
  24. Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
  25. Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
  26. Hankey GJ, Eikelboom JW, Yi Q, et al. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. Stroke 2012;43(6):1572-7. PubMed
  27. Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
  28. Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
  29. Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
  30. Li H, Chen M, Liang S, et al. Excessive vitamin B6 during treatment is related to poor prognosis of patients with nasopharyngeal carcinoma: A U-shaped distribution suggests low dose supplement. Clin Nutr 2021;40(4):2293-2300. PubMed
  31. Tanigawa J, Nabatame S, Tominaga K, et al. High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency. Brain Dev 2021;43(6):680-687. PubMed
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See these in context on the Casein Protein monograph →

Gelatin 11 references
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See these in context on the Gelatin monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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