Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

BCAA 3300 Ingredients & Drug Interactions

by MHP Maximum Human Performance

BCAA 3300 label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking BCAA 3300 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

BCAA 3300 is a dietary supplement by MHP Maximum Human Performance with 5 active ingredients. Its ingredients are commonly taken for riboflavin deficiency, migraine prevention, general energy and metabolism support.Based on those ingredients, 230 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, Riboflavin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against BCAA 3300 by MHP Maximum Human Performance

Ask about any prescription or over-the-counter medication and we check it for interactions with BCAA 3300 by MHP Maximum Human Performance — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of BCAA 3300 by MHP Maximum Human Performance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

BCAA 3300 contains 5 active ingredients: three branched-chain amino acids (L-leucine, L-isoleucine, and L-valine), plus riboflavin (vitamin B2) and vitamin B6. The three BCAAs are amino acids your body uses to build and repair muscle.

Riboflavin is a B vitamin that helps your body turn food into energy, and vitamin B6 plays a role in brain development and immune function. The product also includes several inactive ingredients like cellulose, calcium carbonate, and magnesium stearate, which are fillers and binders that hold the tablet together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Increased muscle growth and improved recovery.
  • We looked for evidence on: Muscle protein synthesis, Athletic performance, Exercise recovery.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The facts we hold don't include effectiveness data for the branched-chain amino acids in this product. For riboflavin, we have no established effectiveness ratings in our data.

Vitamin B6 is effective for sideroblastic anemia and B6 deficiency, likely effective for high homocysteine levels (hyperhomocysteinemia), and possibly effective for pregnancy-induced nausea and vomiting—but the evidence isn't clear for other uses.

The evidence, ingredient by ingredient Riboflavin Vitamin B6

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Riboflavin is very well tolerated and considered safe; any excess is removed through your urine. The most common side effects are dose-related nausea and bright yellow urine.

A small number of trial participants reported diarrhea and increased urination at high doses. Riboflavin is needed during pregnancy and breastfeeding and is safe at standard amounts, though talk with your provider about higher-dose supplements.

Vitamin B6 is well tolerated at doses under 100 mg daily. Common side effects include abdominal pain, headache, nausea, and vomiting.

At high doses over time—especially above 1,000 mg daily or cumulative doses of 1,000 grams or more—it can cause nerve damage (sensory neuropathy), though this can occur even at lower doses. Vitamin B6 is likely safe in pregnancy at recommended amounts but possibly unsafe at high doses; it's likely safe while breastfeeding.

Always avoid high doses unless your doctor advises otherwise.

Side effects, ingredient by ingredient Riboflavin Vitamin B6

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Vitamin B6, Riboflavin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: Parkinson's medications.
  • For scale: 230 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking BCAA 3300, double-check if you use blood pressure medications (antihypertensives)—vitamin B6 may add to their effect. Also check for seizure medications like phenobarbital or phenytoin, the heart medication amiodarone, tetracycline antibiotics, and levodopa for Parkinson's disease.

The interaction checker below will search your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

BCAA 3300 may be worth considering if you're looking to support muscle recovery with branched-chain amino acids and want the added B vitamins. If you take blood pressure medications, seizure medications, amiodarone, tetracycline antibiotics, or levodopa, you should check your exact medications against the interaction tool before starting.

Talk with your pharmacist about whether this product is right for you and your current medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BCAA 3300, straight from the product label.

Brand MHP Maximum Human Performance
Barcode (UPC) 666222940199
Net contents 120 Tablet(s)
Market status On market
Date entered into DSLD Feb 23, 2012
DSLD ID 5717
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BCAA 3300 by MHP Maximum Human Performance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Tablet(s)
Maximum serving Sizes:
4 Tablet(s)
Servings per container
30
UPC/BARCODE
666222940199
IngredientAmount% DV
Riboflavin1.7 mg100%
Vitamin B61.5 mg75%
L-Leucine2200 mg--
L-Isoleucine550 mg--
L-Valine550 mg--

Other ingredients: Microcrystalline Cellulose, Calcium Carbonate, Hydroxypropyl Methylcellulose, Stearic Acid, Methylcellulose, Methylcellulose, Magnesium Stearate, Silica, Titanium Dioxide, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 4 tablets once or twice daily. For optimal use, take 1 serving (4 tablets) before workouts and 1 serving (4 tablets) immediately after your workouts.

Precautions

Keep out of reach of children.

Do not purchase if seal is broken.

NOTICE: Use this product as a food supplement only. Do not use for weight reduction.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Protect from heat, light and moisture.

Store at 15-30(0)C (59-86(0)F).

General Statements

4:1:1 Leucine Loaded Increased Muscle Growth* Improved Recovery*

BCAAs are essential amino acids, which means the body cannot make them and they must be supplied through food or supplementation. An athlete's requirement for BCAAs is even higher than that of ordinary individuals because they serve as "building blocks" for muscle tissue and are also utilized for energy. BCAA 3300's higher levels of leucine, in conjunction with isoleucine and valine, allows for higher anabolic activity and optimal BCAA replenishment for athletes. Additionally, BCAA 3300 has a timed release delivery to provide a continual supply of these key amino acids for optimum anabolic and anti-catabolic effects.*

Branched Chain Amino Acids

MHP Maximum Human Performance

MHP's BCAA 3300 is a super-anabolic Branched Chain Amino Acid complex formulated in a powerful 4:1:1 ratio (leucine: isoleucine: valine) for maximum muscle building and recovery. This highly anabolic ratio sets MHP's BCAA 3300 apart from other formulas that use the outdated 2:1:1 ratio. The newest muscle-building and performance research reports that leucine is the most anabolic of all aminos and activates the mTOR anabolic pathway to increase protein synthesis for enhanced muscle growth and repair.*

mTOR Activated Anabolic Complex

The Most Anabolic BCAA Formula*

TIMED RELEASE

Formula

MHP's BCAA 3300 is the most scientifically advanced anabolic BCAA formula available and is a must for all serious body builders and athletes!*

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

BCAA 3300 by MHP Maximum Human Performance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

BCAA 3300 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in BCAA 3300 by MHP Maximum Human Performance

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Riboflavin

Interacts with
20 drugs
1.7 mg per serving

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...

Riboflavin monograph & interactions

Vitamin B6

Interacts with
210 drugs
1.5 mg per serving

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

L-Leucine

2200 mg per serving

L-Isoleucine

550 mg per serving

L-Valine

550 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Calcium Carbonate, Hydroxypropyl Methylcellulose, Stearic Acid, Methylcellulose, Methylcellulose, Magnesium Stearate, Silica, Titanium Dioxide, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

BCAA 3300 by MHP Maximum Human Performance Drug Interactions

Want to check YOUR meds against BCAA 3300?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
230Drugs
225 Moderate 5 Minor

Ingredients driving the most interactions

Vitamin B6 210
Riboflavin 20

Individual Drug Interactions

The ingredients in BCAA 3300 interact with 230 drugs. Click any drug to see the details.

2 of the 5 ingredients in BCAA 3300 interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6 Riboflavin

Each ingredient & the kinds of drugs it affects

For each ingredient in BCAA 3300 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

Riboflavin1 drug type · 20 drugs

Tetracycline Antibiotics

Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.

Likelihood Possible Evidence D
Riboflavin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for BCAA 3300, from the product label.

MHP Maximum Human Performance

See all MHP Maximum Human Performance products
Name
Maximum Human Performance, Inc.
Street Address
21 Dwight Place
City
Fairfield
State
NJ
ZipCode
07004
Phone Number
1.888.783.8844
Web Address
www.MHPSTRONG.com
Pharmacist Counseling Corner

BCAA 3300 by MHP Maximum Human Performance: Common Questions

Does BCAA 3300 by MHP Maximum Human Performance interact with any medications?
Yes. Based on its ingredients, BCAA 3300 has a known interaction with 230 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BCAA 3300 contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Riboflavin is needed during pregnancy and is safe at recommended amounts. Vitamin B6 is likely safe in pregnancy at standard doses but possibly unsafe at high doses. Talk with your doctor before taking this product during pregnancy to make sure the dose is right for you.
Can I take this while breastfeeding?
Both riboflavin and vitamin B6 are needed while breastfeeding and are considered safe at recommended amounts. For higher doses, check with your provider first.
What are the side effects?
Riboflavin is generally well tolerated; the most common side effect is nausea at higher doses, and it will turn your urine bright yellow. Vitamin B6 can cause nausea, abdominal pain, and headache. At very high doses over time, vitamin B6 can damage nerves (sensory neuropathy).
What do the branched-chain amino acids do?
The three BCAAs—L-leucine, L-isoleucine, and L-valine—are amino acids your body uses to build and repair muscle tissue. They're a popular supplement for athletes and people doing resistance training.
Is this product safe for long-term use?
Riboflavin is very safe long-term. Vitamin B6 is safe at normal amounts, but high doses over extended periods can harm your nerves. Stick to recommended doses and talk with your pharmacist if you plan to take it regularly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BCAA 3300 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BCAA 3300 label
Go deeper

The Full Monographs Behind BCAA 3300’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Riboflavin

Interacts with 20 drugs

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally very safe at typical doses, and the stro...

Read the full Riboflavin monograph → Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph →
Sources

Sources & How We Checked

BCAA 3300's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 37 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Riboflavin 5 references
  1. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology 1998;50:466-70. PubMed
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Leeson LJ, Weidenheimer JF. Stability of tetracycline and riboflavin. J Pharm Sci. 1969;58(3):355-7. PubMed
  4. MacLennan, S. C., Wade, F. M., Forrest, K. M., Ratanayake, P. D., Fagan, E., and Antony, J. High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial. J Child Neurol. 2008;23(11):1300-1304.
  5. Dietary reference intakes (DRIs): estimated average requirements. Food and Nutrition Board, Institute of Medicine, National Academics. https://www.nal.usda.gov/sites/default/files/fnic_uploads//recommended_intakes_individuals.pdf Accessed July 24, 2017.

See these in context on the Riboflavin monograph →

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
  24. Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
  25. Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
  26. Hankey GJ, Eikelboom JW, Yi Q, et al. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. Stroke 2012;43(6):1572-7. PubMed
  27. Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
  28. Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
  29. Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
  30. Li H, Chen M, Liang S, et al. Excessive vitamin B6 during treatment is related to poor prognosis of patients with nasopharyngeal carcinoma: A U-shaped distribution suggests low dose supplement. Clin Nutr 2021;40(4):2293-2300. PubMed
  31. Tanigawa J, Nabatame S, Tominaga K, et al. High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency. Brain Dev 2021;43(6):680-687. PubMed
  32. Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. PubMed

See these in context on the Vitamin B6 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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