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Dietary supplement

Beet Root Capsules Ingredients & Drug Interactions

by Pure

Beet Root Capsules label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beet Root Capsules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Beet Root Capsules is a dietary supplement by Pure with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beet root powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Beet Root Capsules by Pure

Ask about any prescription or over-the-counter medication and we check it for interactions with Beet Root Capsules by Pure — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Beet Root Capsules by Pure

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Pure Beet Root Capsules contains one active ingredient: beet root powder. The capsules are made with gelatin as an inactive ingredient (the capsule shell itself).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beet's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: healthy circulation and blood pressure levels.
  • We looked for evidence on: Hypertension, Pregnancy-induced hypertension, Coronary heart disease (CHD), Dyslipidemia, Hypertriglyceridemia, Raynaud syndrome — and 3 related terms.
  • The closest evidence on file: Beet is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD) (Natural Medicines).
  • Also on file: Beet is rated "Insufficient Reliable Evidence To Rate" for Dyslipidemia, Hypertension, Hypertriglyceridemia, Pregnancy-induced hypertension, and more.

The evidence on beet root is mixed. It's possibly effective for athletic performance and exercise-induced muscle soreness based on the data we hold.

For chronic obstructive pulmonary disease (COPD), the evidence suggests it's possibly ineffective. For cholesterol levels (dyslipidemia) and cognitive function, there isn't enough reliable evidence to rate either way.

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beet as a food is widely eaten and generally well tolerated. However, concentrated beet supplements lack the same safety history, so use caution with this product.

Short-term use appears well tolerated for most adults. The most common side effect is red stools and red urine — harmless discoloration from the beet pigment.

Rarely, black stools have been reported. In very large amounts, beet could theoretically lower calcium levels or damage the kidneys, though this is uncommon.

We don't have data on lactation safety for concentrated beet supplements.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking these capsules, double-check medications broken down by the liver enzyme CYP3A4 (Moderate severity) — a major category that includes many statins, blood pressure drugs, immunosuppressants, and others. Also flag any CYP1A2 substrates (Minor severity) and blood pressure medications (Minor severity) with your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Beet root capsules may appeal to athletes or people focused on exercise recovery, but they interact with a large number of medications through liver enzyme effects. If you take prescription drugs — especially those broken down by your liver — check your list with the tool on this page before starting.

Talk to your pharmacist about whether this product fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beet Root Capsules, straight from the product label.

Brand Pure
Net contents 365 Capsule(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 248635
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beet Root Capsules by Pure, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
122
IngredientAmount% DV
Beet root powder1155 mg--

Other ingredients: Gelatin Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Pure ingredients. Pure results. Unmatched purity.

Gluten-free

100% Natural

Athletic performance Blood pressure Circulatory health

General Statements

Triple the value.

Money Back Guarantee

Made with 1 ingredient

Formula

Highly concentrated beet root for healthy circulation & blood pressure levels

Nitric oxide supplement

Precautions

If you are pregnant, nursing, or taking medication, consult your physician before taking this or any dietary supplement.

For adults only.

Suggested/Recommended/Usage/Directions

Suggested Use: Take 3 capsules daily, or as directed by a physician. Take with at least 8 oz of liquid.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure or prevent any disease or health condition.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beet Root Capsules by Pure label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beet Root Capsules label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beet Root Capsules by Pure

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container122 Amounts shown are per serving.

Beet root powder

Interacts with
861 drugs
1155 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet root powder monograph & interactions

Other (inactive) ingredients: Gelatin Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beet Root Capsules by Pure Drug Interactions

Want to check YOUR meds against Beet Root Capsules?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
861Drugs
643 Moderate 218 Minor

Ingredients driving the most interactions

Beet root powder 861

Individual Drug Interactions

The ingredients in Beet Root Capsules interact with 861 drugs. Click any drug to see the details.

1 of the 1 ingredient in Beet Root Capsules interact with drugs. Each result below shows which ingredient is responsible. Beet root powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Beet Root Capsules with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beet root powder3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Beet root powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beet Root Capsules, from the product label.

Pure

See all Pure products
Name
Pure Supplements
Street Address
2578 W 600 N
City
Lindon
State
UT
ZipCode
84042
Phone Number
801-903-2280
Web Address
Puresupplementsco.com
Pharmacist Counseling Corner

Beet Root Capsules by Pure: Common Questions

Does Beet Root Capsules by Pure interact with any medications?
Yes. Based on its ingredients, Beet Root Capsules has a known interaction with 861 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beet Root Capsules contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will beet root capsules lower my blood pressure?
Beet contains nitrates that theoretically can lower blood pressure, which is why it's flagged as a Minor interaction with blood pressure medications. However, one clinical study of concentrated beetroot juice found no significant blood pressure change in different age groups. The effect isn't guaranteed.
Is red urine or red stools a sign something's wrong?
No — red or even black stools from beet supplements are harmless discoloration caused by the beet pigment and are a common, benign side effect. That said, if you're on blood thinners and develop black stools along with nausea or vomiting, contact your doctor or pharmacist right away.
Does beet root powder actually help with exercise performance?
The evidence suggests it's possibly effective for athletic performance and exercise-induced muscle soreness. That said, the data isn't overwhelming, so results may vary.
Is there any safety data on beet supplements during pregnancy or breastfeeding?
We don't have safety data on file for beet root supplements during lactation. Since the product is a concentrated supplement (not whole food beet), talk with your doctor or pharmacist before using it if you're pregnant or breastfeeding.
Are there any fillers or other inactive ingredients I should know about?
The only inactive ingredient is the gelatin capsule shell. There are no other fillers listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beet Root Capsules is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beet Root Capsules label
Go deeper

The Full Monographs Behind Beet Root Capsules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beet

Interacts with 861 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph →
Sources

Sources & How We Checked

Beet Root Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  9. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  10. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  11. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  12. Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
  13. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  14. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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