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Dietary supplement

Beet Root Extra Strength 2000 mg Ingredients & Drug Interactions

by Futurebiotics

Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Beet Root Extra Strength 2000 mg is a dietary supplement by Futurebiotics with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beet, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Beet Root Extra Strength 2000 mg by Futurebiotics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: beet powder at 2000 mg per serving. Beet is a root vegetable that supplies nitrates and betanin (a natural pigment with antioxidant properties).

The tablet also contains inactive ingredients — microcrystalline cellulose, croscarmellose sodium, stearic acid, magnesium stearate, silicon dioxide, hydroxypropyl methylcellulose, and polyethylene glycol — which are common binding and flow agents used in tablet manufacturing.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support vascular function, circulation and heart health.
  • We looked for evidence on: Hypertension, Coronary heart disease (CHD), Dyslipidemia, Hypertriglyceridemia, Pulmonary hypertension, Raynaud syndrome — and 4 related terms.
  • The strongest evidence on file: Beet is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beet is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD), Dyslipidemia, Hypertension, Hypertriglyceridemia, and more.

Beet shows possibly effective evidence for athletic performance and exercise-induced muscle soreness — meaning some studies support a benefit, but the evidence isn't yet conclusive. For chronic obstructive pulmonary disease (COPD), it's rated possibly ineffective.

The data we hold on beet for high cholesterol (dyslipidemia) and cognitive function is insufficient to rate either way, so we can't say whether it helps for those purposes.

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beet is widely eaten as food and is generally well tolerated for most adults when used short-term for medicinal purposes. However, concentrated beet supplements lack long-term safety data, so use caution.

The most common side effects are red stools and red urine — harmless color changes from the pigment. Rarely, black stools have been reported.

In very large amounts, beet can theoretically cause low blood calcium (hypocalcemia) and kidney damage, though these are rare. Because of a single case report of a person on blood thinners (apixaban and clopidogrel) who had black stools after taking beet pills, stay alert if you're on blood-thinning medications.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check whether you're on any medications broken down by the liver enzyme CYP3A4 (Moderate interaction); blood pressure medications (Minor interaction); or drugs metabolized by the CYP1A2 enzyme (Minor interaction). Altogether, these interactions span 850 individual medications.

Use the search tool on this page to look up your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Beet Root may appeal to athletes looking to support exercise performance and recovery, but it's not a proven winner yet. If you take any prescription medication — especially those broken down by your liver — check it against our interaction tool first.

Talk to your pharmacist before starting, particularly if you're on blood thinners or blood pressure drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beet Root Extra Strength 2000 mg, straight from the product label.

Brand Futurebiotics
Barcode (UPC) X0038ZDIIB
Net contents 360 Vegetarian Tablet(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 321921
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beet Root Extra Strength 2000 mg by Futurebiotics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
180
UPC/BARCODE
X0038ZDIIB
IngredientAmount% DV
Beet, Powder2000 mg--

Other ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Magnesium Stearate, Silicon Dioxide, Hydroxypropyl Methylcellulose, Polyethylene Glycol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Beets naturally contain nitrates, which have been shown to support vascular function, healthy circulation and overall heart health. When ingested, the dietary nitrates are converted into nitric oxide. By doing so, Beets help to dilate blood vessels, which promotes healthy blood flow and supports blood pressure levels that are already in a healthy range. Futurebiotics Beet Root provides 2000 mg of beets per serving (from 4:1 extract) to help the body maintain healthy cardiovascular function.

Laboratory tested GMO-free, gluten-free and soy-free, Futurebiotics Beet Root is in-house tested and carefully manufactured by trained professionals in our state-of-the-art facility that is located in Hauppauge, New York.

Laboratory tested GMO-free, gluten-free and soy-free, Futurebiotics Beet Root is in-house tested and carefully manufactured by trained professionals in our state-of-the-art facility that is located in Hauppauge, New York.

Heart, circulation & stamina

Free of gluten & soy Lab tested GMO free

Formula

Beet Root Extra Strength 2000 mg per serving

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement for adults, take 2 tablets daily, preferably with a meal or as directed by a healthcare professional.

Precautions

Warning: Do not take if you are pregnant or nursing. Consult a healthcare professional prior to use if you are taking any medications.

Do not use if seal under cap is broken or missing.

Keep out of reach of children.

Storage

Store at room temperature.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Lab Tested GMO free

See for yourself

Beet Root Extra Strength 2000 mg by Futurebiotics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Beet Root Extra Strength 2000 mg by Futurebiotics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container180 Amounts shown are per serving.

Beet, Powder

Interacts with
861 drugs
2000 mg per serving Form: Beet Root Extract

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet, Powder monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Magnesium Stearate, Silicon Dioxide, Hydroxypropyl Methylcellulose, Polyethylene Glycol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beet Root Extra Strength 2000 mg by Futurebiotics Drug Interactions

Want to check YOUR meds against Beet Root Extra Strength 2000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
861Drugs
643 Moderate 218 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Beet Root Extra Strength 2000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beet, Powder3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Beet Root Extra Strength 2000 mg, from the product label.

Futurebiotics

See all Futurebiotics products
Name
Futurebiotics
City
Hauppauge
State
NY
ZipCode
11788
Phone Number
(800) 367-5433
Web Address
www.futurebiotics.com
Pharmacist Counseling Corner

Beet Root Extra Strength 2000 mg by Futurebiotics: Common Questions

Does Beet Root Extra Strength 2000 mg by Futurebiotics interact with any medications?
Yes. Based on its ingredients, Beet Root Extra Strength 2000 mg has a known interaction with 861 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beet Root Extra Strength 2000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will beet lower my blood pressure?
Beet contains nitrates that theoretically can relax blood vessels and lower blood pressure, but the evidence is weak — one study of concentrated beetroot juice found no significant blood pressure drop. If you're on blood pressure medication, check with your pharmacist before adding beet.
What's the red color in my urine and stools after taking this?
That's just the natural pigment from beet (betanin). Red urine and red stools are harmless and expected. Black stools have rarely been reported; if that happens or you feel unwell, contact your doctor.
Does beet work for athletic performance?
Beet is rated possibly effective for athletic performance and exercise-induced muscle soreness — meaning some studies show a benefit, but the evidence isn't definitive yet. Your results may vary.
Is beet safe during pregnancy or breastfeeding?
We don't have safety data on file for beet in pregnancy or lactation. Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or breastfeeding.
What are the inactive ingredients in this tablet?
The tablet contains microcrystalline cellulose, croscarmellose sodium, stearic acid, magnesium stearate, silicon dioxide, hydroxypropyl methylcellulose, and polyethylene glycol — all common binding and flow agents.
Can beet damage my kidneys?
Beet contains oxaluric acid, which theoretically could cause kidney damage and low blood calcium only in very large amounts. At the doses in this product used short-term, serious harm is rare, but concentrated beet supplements lack long-term safety data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beet Root Extra Strength 2000 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beet Root Extra Strength 2000 mg label
Go deeper

The Full Monographs Behind Beet Root Extra Strength 2000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Beet Root Extra Strength 2000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  9. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  10. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  11. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  12. Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
  13. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  14. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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