Blue-Green Algae Ingredients & Drug Interactions
by Pure Synergy
What is this page for?
First and foremost: checking Blue-Green Algae against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Blue-Green Algae is a dietary supplement by Pure Synergy with 2 active ingredients. Its ingredients are commonly taken for general nutrition and energy, antioxidant support, cholesterol and metabolic health.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Klamath Lake Blue-Green Algae. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Blue-Green Algae by Pure Synergy
Ask about any prescription or over-the-counter medication and we check it for interactions with Blue-Green Algae by Pure Synergy — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Blue-Green Algae by Pure Synergy
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: organic Klamath Lake blue-green algae, delivered as a powder. There are no inactive ingredients listed.
Does it work?
Not established
The evidence for blue-green algae is mixed. It's rated possibly effective for high blood pressure (hypertension).
For acne, allergic rhinitis (hay fever), iron deficiency anemia, and arsenic poisoning, the evidence isn't established enough to rate — there's insufficient reliable data on file. So if you're considering it for blood pressure support, there's some backing; for other uses, we don't have solid evidence to point to.
How safe is it?
Well-documented data
Blue-green algae is generally well tolerated when taken by mouth. The most common side effects are digestive — abdominal cramps, bloating, diarrhea, nausea, and vomiting — along with dizziness, fatigue, headache, and flatulence.
Allergic reactions, including rashes, itching, and in rare cases severe reactions like anaphylaxis, have been reported. A few people taking the algae have experienced mild gum bleeding or bruising.
The biggest safety concern is quality control: some blue-green algae products can be contaminated with toxins or heavy metals, and contamination risk is real enough that the data advises caution when choosing a product.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your own doctor or pharmacist if you take anticoagulants or antiplatelet drugs (like warfarin or aspirin), immunosuppressants, or antidiabetes medications. The algae may increase bleeding risk with blood thinners, interfere with immune-suppressing drugs, and lower blood sugar more than expected with diabetes medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Blue-Green Algae by Pure Synergy may help with high blood pressure, but it's not established for other common uses. It's generally well tolerated, but quality varies — pick carefully to avoid contamination.
If you take blood thinners, immunosuppressants, or diabetes drugs, check with your doctor or pharmacist before starting, since interactions are possible.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Blue-Green Algae, straight from the product label.
| Brand | Pure Synergy |
|---|---|
| Barcode (UPC) | 852971004262 |
| Net contents | 3.2 oz; 90 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Apr 22, 2021 |
| DSLD ID | 247468 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Kosher, Organic, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Blue-Green Algae by Pure Synergy, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 5 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | 1% |
| Protein | 1 Gram(s) | 2% |
| organic Klamath Lake Blue-Green Algae | 1500 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Energy clarity boost
For more recipe ideas, visit our website and follow us @pure_synergy.
Packaged by weight, not volume. Contents may settle.
Formula
Blue-Green Algae is one of nature's most cleansing, nourishing, and chlorophyll-rich superfoods. The unique, pristine growing environment of Upper Klamath Lake where our algae grows ensures unparalleled purity and mineral content.
OU (Kosher) Certified Kosher
Organic pure Klamath Crystals
Formulation
Cold-dried to perfection and third party tested for purity, our organic Blue-Green Algae supports healthy energy, mental clarity and focus.
Oregon Tilth Certified Organic (OTCO)
Non GMO
No GMO's, dairy or gluten.
Suggested/Recommended/Usage/Directions
Suggested use: Mix 1 tsp with 4-6 oz filtered water or juice in a lidded jar and shake briskly, or add to your favorite smoothie.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
Oregon Tilth Certified Organic (OTCO) OU (Kosher) Certified Kosher
USDA Organic
FDA Statement of Identity
Dietary Supplement
Storage
For optimal freshness, use a dry spoon and close lid tightly after each use. If some caking should occur from natural humidity, not to worry, the powder's benefits will not be compromised.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Blue-Green Algae by Pure Synergy label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Blue-Green Algae by Pure Synergy
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tsp(s) Dosage formPowder Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Protein
Organic Klamath Lake Blue-Green Algae
Interacts with327 drugs
Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and...
Organic Klamath Lake Blue-Green Algae monograph & interactionsBlue-Green Algae by Pure Synergy Drug Interactions
HelloPharmacist Interaction Report
Pure Synergy's Blue-Green Algae is a single-ingredient powder made from organic Klamath Lake blue-green algae.
It does interact with certain medications, and the most serious concern is with blood thinners (anticoagulants) and antiplatelet drugs — the algae may theoretically increase bleeding risk, though this is unlikely based on available evidence.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to be cautious if you take immunosuppressants (drugs that dampen your immune system), since blue-green algae can stimulate immune activity and might interfere with those medications. Similarly, if you take diabetes medications, there's a moderate interaction risk: the algae appears to lower blood sugar in some people with diabetes, which could tip you toward low blood sugar (hypoglycemia) when combined with antidiabetes drugs.
Altogether, these interactions span 327 individual medications. Before you start this product, run your exact medications through the interaction checker on this page, and definitely talk with your own doctor or pharmacist if you're on any blood thinner, immunosuppressant, or diabetes medication.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Blue-Green Algae?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Blue-Green Algae interact with 327 drugs. Click any drug to see the details.
1 of the 2 ingredients in Blue-Green Algae interact with drugs. Each result below shows which ingredient is responsible. organic Klamath Lake Blue-Green Algae
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Klamath Lake Blue-green Algae + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Klamath Lake Blue-green Algae + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Klamath Lake Blue-green Algae + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Klamath Lake Blue-green Algae + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Klamath Lake Blue-green Algae + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Klamath Lake Blue-green Algae + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Klamath Lake Blue-green Algae + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Klamath Lake Blue-green Algae + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Klamath Lake Blue-green Algae + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Klamath Lake Blue-green Algae + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Klamath Lake Blue-green Algae + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Klamath Lake Blue-green Algae + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Klamath Lake Blue-green Algae + Alemtuzumab interactionAlogliptinNesina
How Alogliptin interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Klamath Lake Blue-green Algae + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Klamath Lake Blue-green Algae + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Klamath Lake Blue-green Algae + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Anagrelide interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Klamath Lake Blue-green Algae + Anifrolumab-fnia interactionAnisindioneMiradon
How Anisindione interacts with Blue-Green Algae — through 1 ingredient. Tap an ingredient for the detail:
Organic Klamath Lake Blue-green AlgaeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Klamath Lake Blue-green Algae + Anisindione interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Blue-Green Algae with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Klamath Lake Blue-Green Algae
Anticoagulant/Antiplatelet Drugs
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs. However, this is unlikely.
Spirulina blue-green algae have shown antiplatelet and anticoagulant effects in vitro. However, one preliminary study in 24 patients receiving spirulina blue-green algae 2.3 grams daily for 2 weeks showed no effect on platelet activation or measures of clotting time.
Antidiabetes Drugs
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Human research shows that spirulina blue-green algae can have hypoglycemic effects in patients with diabetes, at least some of whom were using antidiabetes drugs. However, blue-green algae does not seem to improve glycated hemoglobin (HbA1c) levels in patients with diabetes. A meta-analysis of animal studies also suggests that spirulina blue-green algae have hypoglycemic effects.
Immunosuppressants
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Blue-green algae have been shown to stimulate the immune system.
Brand information
Manufacturer and brand details for Blue-Green Algae, from the product label.
Pure Synergy
See all Pure Synergy products- Name
- The Synergy Company
- City
- Moab
- State
- Utah
- ZipCode
- 84532
- Phone Number
- 800-723-0277
- Web Address
- thesynergycompany.com
Blue-Green Algae by Pure Synergy: Common Questions
Does Blue-Green Algae by Pure Synergy interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What are the most common side effects?
Is it really just algae, or does it have fillers?
How do I know if my product is contaminated?
Does this really help with high blood pressure?
Can I take this if I'm allergic to seafood?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Blue-Green Algae is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Blue-Green Algae’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Blue-Green Algae's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 22 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Blue-green Algae 22 references
- Jensen GS, Ginsberg DJ, Huerta P, et al. Consumption of Aphanizomenon flos-aquae has rapid effects on the circulation and function of immune cells in humans. A novel approach to nutritional mobilization of the immune system. JANA 2000;2:50-6.
- Iwasa M, Yamamoto M, Tanaka Y, et al. Spirulina-associated hepatotoxicity. Am J Gastroenterol 2002;97:3212-13. PubMed
- Hayashi O, Katoh T, Okuwaki Y. Enhancement of antibody production in mice by dietary Spirulina platensis. J Nutr Sci Vitaminol (Tokyo) 1994;40:431-41.. PubMed
- Vitale S, Miller NR, Mejico LJ, et al. A randomized, placebo-controlled, crossover clinical trial of super blue-green algae in patients with essential blepharospasm or Meige syndrome. Am J Ophthalmol 2004;138:18-32. PubMed
- Mani UV, Desai S, Iyer U. Studies on the long-term effect of spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients. J Nutraceut 2000;2(3):25-32. DOI
- Chiu HF, Yang SP, Kuo YL, et al. Mechanisms involved in the antiplatelet effect of C-phycocyanin. Br J Nutr 2006;95:435-40. PubMed
- Hsiao G, Chou PH, Shen MY, et al. C-phycocyanin, a very potent and novel platelet aggregation inhibitor from Spirulina platensis. J Agric Food Chem 2005;53:7734-40.
- Katz M, Levine AA, Kol-Degani H, Kav-Venaki L. A compound herbal preparation (CHP) in the treatment of children with ADHD: a randomized controlled trial. J Atten Disord 2010;14:281-91. PubMed
- Madhyastha, H. K., Radha, K. S., Sugiki, M., Omura, S., and Maruyama, M. Purification of c-phycocyanin from Spirulina fusiformis and its effect on the induction of urokinase-type plasminogen activator from calf pulmonary endothelial cells. Phytomedicine PubMed
- Mazokopakis, E. E., Karefilakis, C. M., Tsartsalis, A. N., Milkas, A. N., and Ganotakis, E. S. Acute rhabdomyolysis caused by Spirulina (Arthrospira platensis). Phytomedicine. 2008;15(6-7):525-527. PubMed
- Halidou, Doudou M., Degbey, H., Daouda, H., Leveque, A., Donnen, P., Hennart, P., and Dramaix-Wilmet, M. [The effect of spiruline during nutritional rehabilitation: systematic review]. Rev.Epidemiol.Sante Publique 2008;56(6):425-431.
- Konno, T., Umeda, Y., Umeda, M., Kawachi, I., Oyake, M., and Fujita, N. [A case of inflammatory myopathy with widely skin rash following use of supplements containing Spirulina]. Rinsho Shinkeigaku 2011;51(5):330-333. PubMed
- Le TM, Knulst AC, Röckmann H. Anaphylaxis to Spirulina confirmed by skin prick test with ingredients of Spirulina tablets. Food Chem Toxicol 2014;74:309-10. PubMed
- Rzymski P, Niedzielski P, Kaczmarek N, Jurczak T, Klimaszyk P. The multidisciplinary approach to safety and toxicity assessment of microalgae-based food supplements following clinical cases of poisoning. Harmful Algae 2015;46:34-42. DOI
- Petrus M, Culerrier R, Campistron M, et al. First case report of anaphylaxis to spirulin: identification of phycocyanin as responsible allergen. Allergy 2010;65(7):924-5. PubMed
- Marles RJ, Barrett ML, Barnes J, et al. United States Pharmacopeia safety evaluation of spirulina. Crit Rev Food Sci Nutr 2011;51(7):593-604. PubMed
- Majdoub H, Ben Mansour M, Chaubet F, et al. Anticoagulant activity of a sulfated polysaccharide from the green alga Arthrospira platensis. Biochim Biophys Acta 2009;1790(10):1377-81. PubMed
- Cha BG, Kwak HW, Park AR, et al. Structural characteristics and biological performance of silk fibroin nanofiber containing microalgae spirulina extract. Biopolymers 2014;101(4):307-18. PubMed
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