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Dietary supplement

BroccoCap Ingredients & Drug Interactions

by Intensive Nutrition

BroccoCap label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking BroccoCap against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

BroccoCap is a dietary supplement by Intensive Nutrition with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, general cellular health, detoxification support.Based on those ingredients, 805 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sulforaphane, Broccoli, Daikon. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against BroccoCap by Intensive Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with BroccoCap by Intensive Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of BroccoCap by Intensive Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

BroccoCap contains three active ingredients: sulforaphane (a compound from broccoli known for its potential anti-inflammatory properties), broccoli powder, and daikon (a type of radish). Together they're meant to deliver the bioactive constituents found in cruciferous vegetables—glucosinolates and their breakdown products—in concentrated form.

The product also contains inactive ingredients: dried broccoli, daikon, and magnesium stearate (a binder).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Prostate cancer — rated "Possibly Effective" (Sulforaphane) (Natural Medicines).
  • On file: Colorectal cancer — rated "Possibly Effective" (Broccoli) (Natural Medicines).

The evidence for BroccoCap's ingredients is mixed and incomplete. Sulforaphane is rated possibly effective for prostate cancer, but the evidence for hay fever, asthma, and general cancer prevention is insufficient to say whether it works.

Broccoli is rated possibly effective for colorectal cancer, though the evidence for breast cancer, lung cancer, heart disease, and other cancers is also insufficient. Daikon (radish) has no established evidence for either diabetes or biliary disorders in the data we hold.

In short, the strongest case here is for prostate and colorectal cancer, but don't expect this to be a proven cure—the evidence is preliminary.

The evidence, ingredient by ingredient Sulforaphane Broccoli Radish

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sulforaphane from food is considered safe, but concentrated supplements like this one are less studied for long-term use. The main side effects reported are bowel discomfort, heartburn, stomach upset, vomiting, and headache.

A small number of trial participants taking sulforaphane experienced insomnia or irritability; two cases of seizure have been reported in males with autism, and one study found participants gained an average of 4 pounds extra over 18 weeks compared to placebo. Broccoli as a food is well tolerated, but concentrated extracts can cause loose stools, diarrhea, abdominal pain, and cramping at high doses.

Daikon in normal food amounts is safe, though large amounts may irritate your digestive tract or cause indigestion. Because this is a concentrated supplement, talk with your doctor or pharmacist before starting if you have a history of seizures, digestive issues, or diabetes.

Side effects, ingredient by ingredient Sulforaphane Broccoli Radish

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Radish, Sulforaphane, Broccoli.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 806 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start BroccoCap, double-check any medications your body processes through these liver enzymes: CYP3A4 substrates (sulforaphane may raise their levels), CYP1A2 and CYP2A6 substrates (broccoli may lower their effects), and CYP2E1 substrates (sulforaphane may raise their levels). Also tell your pharmacist if you take diabetes drugs, because daikon may lower your blood sugar.

If you take seizure medications or have a history of seizures, discuss this product with your doctor first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

BroccoCap might appeal to you if you're interested in concentrated cruciferous vegetable compounds and you're not taking medications metabolized by your liver. If you take any prescription drugs—especially those for diabetes, heart rhythm, mental health, or cancer—you need to check them against this product before starting, because the interactions are numerous and potentially serious.

Talk with your doctor or pharmacist about whether it fits your individual situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BroccoCap, straight from the product label.

Brand Intensive Nutrition
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2013
DSLD ID 23605
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BroccoCap by Intensive Nutrition , sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
IngredientAmount% DV
Sulforaphane2 mg--
Broccoli450 mg--
Daikon50 mg--

Other ingredients: Dried broccoli, Daikon, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

CAUTION: KEEP THE BTL CLOSED IN A COOL DRY PLACE AND OUT OF THE REACH OF CHILDREN

General Statements

Made is U.S.A.

Suggested/Recommended/Usage/Directions

Directions: 2 capsules 3X daily, before meals or as directed by your health professional

Formula

Broccoli Sprouts

Each capsule contains 500 mg of freeze dried Broccoli (Brassica oleracea italica), which is rich in Indole-3-carbinols and daikon (Raphanus sativus) seed sprouts Sprouted in sulfur-rich media, providing approximately 2 mg of pure sulforaphane the phase 2 detox enzyme activator

FDA Statement of Identity

Dietary Supplement

Formulation

FREE OF YEAST, SUGAR, STARCH, ARTIFICIAL COLORS, SWEETENERS OR PRESERVATIVES

Storage

CAUTION: KEEP THE BTL CLOSED IN A COOL DRY PLACE AND OUT OF THE REACH OF CHILDREN

General

#81

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

BroccoCap by Intensive Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

BroccoCap label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in BroccoCap by Intensive Nutrition

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sulforaphane

Interacts with
724 drugs
2 mg per serving

Sulforaphane is a natural compound found in broccoli and other cruciferous vegetables that has shown promising antioxidant and anti-inflammatory effec...

Sulforaphane monograph & interactions

Broccoli

Interacts with
187 drugs
450 mg per serving

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Broccoli monograph & interactions

Daikon

Interacts with
86 drugs
50 mg per serving

Radish is a common edible root vegetable that is nutritious and generally safe to eat as food. Some people use radish (especially black radish) and it...

Daikon monograph & interactions

Other (inactive) ingredients: Dried broccoli, Daikon, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

BroccoCap by Intensive Nutrition Drug Interactions

Want to check YOUR meds against BroccoCap?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
805Drugs
805 Moderate

Ingredients driving the most interactions

Sulforaphane 724
Broccoli 187
Daikon 86

Individual Drug Interactions

The ingredients in BroccoCap interact with 805 drugs. Click any drug to see the details.

3 of the 3 ingredients in BroccoCap interact with drugs. Each result below shows which ingredient is responsible. Sulforaphane Broccoli Daikon

Each ingredient & the kinds of drugs it affects

For each ingredient in BroccoCap with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sulforaphane3 drug types · 724 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Animal and in vitro research shows that sulforaphane inhibits CYP1A2 enzyme activity. However, its precursor glucoraphanin also appears to increase the expression of the CYP1A2 enzyme, which could lead to increased metabolism of CYP1A2 substrates. These effects have not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, sulforaphane might increase the levels and effects of CYP2E1 substrates.
In vitro evidence shows that sulforaphane inhibits CYP2E1 enzymes. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Animal and in vitro research shows that sulforaphane inhibits CYP3A4 enzyme activity and downregulates its expression. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Sulforaphane full monograph & interactions

Broccoli2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Broccoli full monograph & interactions

Daikon1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, radish might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that radish extract, juice, and sprouts can reduce glucose levels. Animal research also shows that radish root juice 300 mg/kg reduces fasting and postprandial blood glucose in a rat model of diabetes, with effects similar to glibenclamide.

Likelihood Possible Evidence D
Daikon full monograph & interactions
The maker

Brand information

Manufacturer and brand details for BroccoCap, from the product label.

Intensive Nutrition

See all Intensive Nutrition products
Name
Intensive Nutrition Inc.
City
San Leandro
State
CA
ZipCode
94577
Phone Number
800-333-7414
Pharmacist Counseling Corner

BroccoCap by Intensive Nutrition : Common Questions

Does BroccoCap by Intensive Nutrition interact with any medications?
Yes. Based on its ingredients, BroccoCap has a known interaction with 805 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BroccoCap contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant or breastfeeding?
Sulforaphane as a concentrated supplement hasn't been proven safe in pregnancy, so avoid it and stick to normal food amounts if you're pregnant. Broccoli and daikon as foods are considered likely safe in pregnancy. For breastfeeding, there isn't enough data on supplement-level doses of sulforaphane, so talk with your doctor or pharmacist before using this product.
What are the most common side effects I might notice?
The most common ones are bowel discomfort, heartburn, stomach upset, and vomiting. Some people have reported headache, insomnia, or irritability. If you eat it, you might also notice loose stools or cramping, especially at higher doses.
Does this actually work for cancer?
Sulforaphane is rated possibly effective for prostate cancer specifically, and broccoli is possibly effective for colorectal cancer. For other cancers and general prevention, the evidence in our data is too weak to say it works. These are preliminary findings, not proven treatments.
What is sulforaphane and why is it in here?
Sulforaphane is a natural compound found in broccoli and other cruciferous vegetables. It's included because lab research suggests it may have anti-inflammatory and potentially cancer-fighting properties, though human evidence is still limited.
Why can't I just eat broccoli instead of taking this supplement?
You can, and broccoli as food is safe. This supplement is a concentrated form—it packs in more of the active compounds than you'd get from a serving of broccoli. But because it's concentrated, it's less studied for long-term safety, and the interactions with medications may be stronger.
Will this lower my blood sugar if I take diabetes medication?
Daikon (radish) in this product may theoretically increase the risk of low blood sugar when combined with diabetes drugs, based on animal research. If you take diabetes medication, check with your doctor or pharmacist before starting BroccoCap.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BroccoCap label
Go deeper

The Full Monographs Behind BroccoCap’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sulforaphane

Interacts with 724 drugs

Sulforaphane is a natural compound found in broccoli and other cruciferous vegetables that has shown promising antioxidant and anti-inflammatory effects in lab studies, but strong human evid...

Read the full Sulforaphane monograph → Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph → Herb & supplement monograph

Radish

Interacts with 86 drugs

Radish is a common edible root vegetable that is nutritious and generally safe to eat as food. Some people use radish (especially black radish) and its extracts for digestion and liver suppo...

Read the full Radish monograph →
Sources

Sources & How We Checked

BroccoCap's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sulforaphane 16 references
  1. Park EJ, Pezzuto JM. Botanicals in cancer chemoprevention. Cancer Metastasis Rev 2002;21:231-55. PubMed
  2. Barcelo S, Mace K, Pfeifer AM, Chipman JK. Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo[4,5-f]quinoline in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane. Mutat Res 1998;402:111-20. PubMed
  3. Cipolla BG, Mandron E, Lefort JM, et al. Effect of sulforaphane in men with biochemical recurrence after radical prostatectomy. Cancer Prev Res (Phila). 2015;8(8):712-9. PubMed
  4. Fahey JW, Wade KL, Wehage SL, et al. Stabilized sulforaphane for clinical use: Phytochemical delivery efficiency. Mol Nutr Food Res. 2017 Apr;61(4). PubMed
  5. Alumkal JJ, Slottke R, Schwartzman J, et al. A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer. Invest New Drugs. 2015;33(2):480-9. PubMed
  6. Heber D, Li Z, Garcia-Lloret M, et al. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food Funct. 2014;5(1):35-41. PubMed
  7. Singh K, Connors SL, Macklin EA, et al. Sulforaphane treatment of autism spectrum disorder (ASD). Proc Natl Acad Sci U S A. 2014;111(43):15550-5. PubMed
  8. Wise RA, Holbrook JT, Criner G, et al. Lack of effect of oral sulforaphane administration on Nrf2 expression in COPD: A randomized, double-blind, placebo controlled trial. PLoS One. 2016;11(11):e0163716. PubMed
  9. Bent S, Lawton B, Warren T, et al. Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli. Mol Autism. 2018;9:35. PubMed
  10. Momtazmanesh S, Amirimoghaddam-Yazdi Z, Moghaddam HS, Mohammadi MR, Akhondzadeh S. Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double-blind, placebo-controlled clinical trial. Psychiatr PubMed
  11. Fimognari C, Lenzi M, Hrelia P. Interaction of the isothiocyanate sulforaphane with drug disposition and metabolism: pharmacological and toxicological implications. Curr Drug Metab. 2008;9(7):668-78. PubMed
  12. Chinnappan SM, George A, Evans M, Anthony J. Efficacy of Labisia pumila and Eurycoma longifolia standardised extracts on hot flushes, quality of life, hormone and lipid profile of peri-menopausal and menopausal women: a randomised, placebo-controlled stud
  13. Mahéo K, Morel F, Langouët S, et al. Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes. Cancer Res. 1997;57(17):3649-52.
  14. Yoxall V, Kentish P, Coldham N, Kuhnert N, Sauer MJ, Ioannides C. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity. Int J Cancer. 2005;117(3):356-62. PubMed
  15. Zimmerman AW, Singh K, Connors SL, et al. Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder. Mol Autism 2021;12(1):38.
  16. Yusin J, Wang V, Henning SM, et al. The effect of broccoli sprout extract on seasonal grass pollen-induced allergic rhinitis. Nutrients 2021;13(4):1337. PubMed

See these in context on the Sulforaphane monograph →

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Radish 5 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Damiani E, Aloia AM, Priore MG, Nardulli S, Ferrannini A. Generalized urticaria after ingestion of Raphanus sativus. Ann Allergy Asthma Immunol. 2011 Feb;106(2):168. PubMed
  3. Evans M, Paterson E, Barnes DM. An open label pilot study to evaluate the efficacy of Spanish black radish on the induction of phase I and phase II enzymes in healthy male subjects. BMC Complement Altern Med. 2014 Dec 9;14:475. PubMed
  4. Banihani SA. Radish (Raphanus sativus) and diabetes. Nutrients. 2017;9(9). pii: E1014. PubMed
  5. Shukla S, Chatterji S, Mehta S, Rai PK, Singh RK, Yadav DK, Watal G. Antidiabetic effect of Raphanus sativus root juice. Pharm Biol. 2011 Jan;49(1):32-7.

See these in context on the Radish monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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