Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Chen Pi Ingredients & Drug Interactions

by Herbal Terra

Chen Pi label
See full label image
Liquid Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chen Pi against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Chen Pi is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for source of vitamin c, digestive support, aromatherapy and relaxation.Based on those ingredients, 643 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are wildcrafted Chen Pi (Citrus reticulata) dried peel liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Chen Pi by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with Chen Pi by Herbal Terra — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Chen Pi by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: wildcrafted Chen Pi, a liquid extract of dried tangerine peel. The menstruum listed is an inactive ingredient — the liquid used to make the extract.

That's it.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Tangerine product and its label doesn't state a use — see Tangerine's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold for tangerine peel and cancer is insufficient — we don't have reliable data to rate how well it works for that purpose. If you're considering this for a specific health goal, chat with your doctor or pharmacist about what the research actually supports.

The evidence, ingredient by ingredient Tangerine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tangerine fruit as food is generally well tolerated. However, the safety data we hold cautions that concentrated extracts like this one — and tangerine essential oil — haven't been studied thoroughly enough to call them safe without medical guidance.

Very few adverse effects have been reported with medicinal tangerine use, though a thorough safety evaluation hasn't been done. Topically, tangerine essential oil has been linked to contact dermatitis (skin irritation) in case reports.

We hold no pregnancy or breastfeeding data for this ingredient, so there isn't enough information to know whether it's appropriate during pregnancy or while nursing. Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or breastfeeding.

Side effects, ingredient by ingredient Tangerine

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tangerine.
  • The most serious interaction on file is rated Minor.
  • For scale: 644 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Chen Pi, double-check any medications that depend on the liver enzyme CYP3A4 to be broken down — a large group that includes over 600 drugs, such as midazolam (Versed). Lab work suggests tangerine peel may speed up how this enzyme works, but human studies paint a mixed picture, so it's worth confirming with your own pharmacist or doctor that this product won't interfere with how your specific medications work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Chen Pi is a single concentrated extract of tangerine peel. The safety data cautions that concentrated forms like this haven't been well studied, so medical guidance is wise before starting.

Because the ingredient may affect how your body handles hundreds of medications, check your exact drugs with the tool on this page — and run the full list by your doctor or pharmacist before you take it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chen Pi, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7429523879802
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 234664
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chen Pi by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
7429523879802
IngredientAmount% DV
wildcrafted Chen Pi (Citrus reticulata) dried peel liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Manufactured in the USA in an FDA registered facility

Alcohol free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Alcohol-free liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Citrus reticulata

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chen Pi by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chen Pi label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chen Pi by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Wildcrafted Chen Pi (Citrus reticulata) dried peel liquid extract

Interacts with
643 drugs
970 mg per serving

Tangerine is a sweet citrus fruit that is a good source of vitamin C and other nutrients, and is widely enjoyed as food. While the peel and essential...

Wildcrafted Chen Pi (Citrus reticulata) dried peel liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chen Pi by Herbal Terra Drug Interactions

Want to check YOUR meds against Chen Pi?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
643Drugs
643 Minor

Ingredients driving the most interactions

wildcrafted Chen Pi (Citrus reticulata) dried peel liquid extract 643

Individual Drug Interactions

The ingredients in Chen Pi interact with 643 drugs. Click any drug to see the details.

1 of the 1 ingredient in Chen Pi interact with drugs. Each result below shows which ingredient is responsible. wildcrafted Chen Pi (Citrus reticulata) dried peel liquid extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Chen Pi with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wildcrafted Chen Pi (Citrus reticulata) dried peel liquid extract2 drug types · 643 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4). This suggests that tangeretin may stimulate CYP3A4 activity. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam, a CYP3A4 substrate. Theoretically, tangerine juice might increase CYP3A4 activity and decrease levels of drugs metabolized by this enzyme. However, this effect is unlikely.
Some drugs metabolized by CYP3A4 include amitriptyline (Elavil), amiodarone (Cordarone), citalopram (Celexa), felodipine (Plendil), lansoprazole (Prevacid), ondansetron (Zofran), prednisone (Deltasone, Orasone), sertraline (Zoloft), sibutramine (Meridia), and many others.

Likelihood Unlikely Evidence B
Midazolam (Versed)

In vitro, tangeretin, a constituent of tangerine, appears to increase the metabolism of midazolam in human liver microsomes by up to 52%. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam. Theoretically, tangerine juice might increase the metabolism and reduce the effects of midazolam. However, this effect is unlikely.

Likelihood Unlikely Evidence B
wildcrafted Chen Pi (Citrus reticulata) dried peel liquid extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chen Pi, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

Chen Pi by Herbal Terra: Common Questions

Does Chen Pi by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Chen Pi has a known interaction with 643 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chen Pi contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Chen Pi?
Chen Pi is the dried peel of tangerine fruit, traditionally used in herbal practice. This product is a liquid extract of that peel — more concentrated than eating the fruit itself.
Is tangerine peel safe to take as a supplement?
Tangerine fruit is fine as food and generally well tolerated. But concentrated extracts like this one aren't as well studied for safety, so the facts here caution using them with medical guidance. Talk with your doctor or pharmacist before you start.
Can Chen Pi interfere with my medications?
Yes — a compound in tangerine called tangeretin may affect how your liver breaks down many drugs (over 600 listed in our data). Lab studies suggested it could speed up that process, but human studies of tangerine juice showed mixed results. Because this is a concentrated extract, not juice, check your exact medications with the tool on this page and confirm with your pharmacist or doctor before taking it.
Does Chen Pi work for cancer?
The evidence we hold for tangerine peel and cancer is insufficient — we don't have reliable data to rate how well it works. This isn't a proven cancer treatment.
Is it safe to take Chen Pi while pregnant or breastfeeding?
We don't hold pregnancy or breastfeeding safety data for tangerine extract, so there isn't enough information to know either way. Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or nursing.
What adverse effects has tangerine caused?
Very few adverse effects have been reported with medicinal use of tangerine — but a thorough safety evaluation hasn't been done. If applied to skin, the essential oil has caused contact dermatitis in case reports.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chen Pi is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chen Pi label
Go deeper

The Full Monographs Behind Chen Pi’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tangerine

Interacts with 643 drugs

Tangerine is a sweet citrus fruit that is a good source of vitamin C and other nutrients, and is widely enjoyed as food. While the peel and essential oil are used in traditional medicine and...

Read the full Tangerine monograph →
Sources

Sources & How We Checked

Chen Pi's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tangerine 3 references
  1. Yuan, J. M., Wang, X. L., Xiang, Y. B., Gao, Y. T., Ross, R. K., and Yu, M. C. Preserved foods in relation to risk of nasopharyngeal carcinoma in Shanghai, China. Int J Cancer 2000;85(3):358-363. DOI
  2. Backman, J. T., Maenpaa, J., Belle, D. J., Wrighton, S. A., Kivisto, K. T., and Neuvonen, P. J. Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation. Clin Pharmacol Ther 2000; PubMed
  3. Vilaplana, J. and Romaguera, C. Contact dermatitis from the essential oil of tangerine in fragrance. Contact Dermatitis 2002;46(2):108. PubMed

See these in context on the Tangerine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team