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Dietary supplement

Eyebright Ingredients & Drug Interactions

by Pure Herbs

Eyebright label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Eyebright against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Eyebright is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for eye irritation and redness, conjunctivitis (pink eye), eye strain.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eyebright Aerial Parts Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Eyebright by Pure Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Eyebright by Pure Herbs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Eyebright by Pure Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid contains one active ingredient: Eyebright Aerial Parts Extract. Eyebright is a plant historically used in herbal medicine for eye and respiratory health, though the evidence for most of its claimed uses is still being investigated.

There are no inactive ingredients listed for this product.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Eyebright's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: maintenance of eye and sinus health.
  • We looked for evidence on: Asthenopia (eye strain), Conjunctivitis, Allergic rhinitis (hay fever), Rhinosinusitis, eye irritation, nasal congestion.
  • The closest evidence on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Rhinosinusitis, Asthenopia (eye strain), Conjunctivitis.

The evidence for eyebright isn't well established in the data we hold. We have insufficient reliable evidence to rate it for allergic rhinitis (hay fever), cough, common cold, pharyngitis, rhinosinusitis, or cancer.

That doesn't mean it doesn't work — it means the research so far isn't strong enough for us to say whether it does.

The evidence, ingredient by ingredient Eyebright

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, eyebright is generally well tolerated in small amounts as a tea, but a small number of people have reported confusion, headache, nausea, constipation, cough, shortness of breath, and nasal congestion. One important caution: using homemade or non-sterile preparations directly in the eye carries real risk of infection and damage.

Safety data for pregnancy is not established, so the safety data advises against use during pregnancy. There isn't enough information to know whether it's safe while breastfeeding — talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Eyebright

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eyebright.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any antidiabetes drugs (blood sugar medications) you take before starting eyebright. Animal data suggests it may lower blood glucose, raising the risk of low blood sugar when combined with diabetes medication.

Your doctor or pharmacist can review your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Eyebright is a plant extract with a long history in herbal use, but current evidence doesn't reliably support its effectiveness for most common uses. If you take diabetes medication, check your specific drugs before starting — the risk of low blood sugar is a real concern.

Talk with your doctor or pharmacist to see whether this product fits your health plan.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Eyebright, straight from the product label.

Brand Pure Herbs
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 279759
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Eyebright by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
60
IngredientAmount% DV
Eyebright Aerial Parts Extract1873 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.

Shake well before use

Formulation

Beneficial for the maintenance of eye and sinus health.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.

Discontinue use and consult with your doctor if any adverse reactions occur.

Keep out of reach of children

Brand IP Statement(s)

Pure Herbs, Ltd. Natural Herbal Extracts

FDA Statement of Identity

Dietary Supplement

General Statements

"No expense has been spared to provide the finest nature has to offer."

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Eyebright by Pure Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Eyebright label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Eyebright by Pure Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Eyebright Aerial Parts Extract

Interacts with
86 drugs
1873 mg per serving

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. Th...

Eyebright Aerial Parts Extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Eyebright by Pure Herbs Drug Interactions

Want to check YOUR meds against Eyebright?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Eyebright Aerial Parts Extract 86

Individual Drug Interactions

The ingredients in Eyebright interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Eyebright interact with drugs. Each result below shows which ingredient is responsible. Eyebright Aerial Parts Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Eyebright with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Eyebright Aerial Parts Extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that eyebright lowers blood glucose levels.

Likelihood Possible Evidence D
Eyebright Aerial Parts Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Eyebright, from the product label.

Pure Herbs

See all Pure Herbs products
Name
Pure Herbs, Ltd.
City
Sterling Heights
State
MI
Phone Number
(800) 860-4372
Web Address
www.pureherbs.com
Pharmacist Counseling Corner

Eyebright by Pure Herbs: Common Questions

Does Eyebright by Pure Herbs interact with any medications?
Yes. Based on its ingredients, Eyebright has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Eyebright contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use eyebright for hay fever?
Eyebright is traditionally used for allergic rhinitis (hay fever), but we don't have enough reliable evidence to say whether it actually works for it. Talk with your doctor about whether to try it.
Is it safe to put eyebright directly in my eyes?
No — using homemade or non-sterile eyebright preparations directly in the eye is risky and can lead to infection or damage. Stick to taking it by mouth as a tea or in this liquid form.
What side effects might I notice?
A small number of people have reported confusion, headache, nausea, constipation, cough, shortness of breath, and nasal congestion when taking eyebright by mouth.
Can I take eyebright if I'm pregnant or breastfeeding?
The safety data advises against eyebright during pregnancy. During breastfeeding, there isn't enough information to know either way — talk with your doctor or pharmacist before use.
Can I take eyebright with my diabetes medication?
Animal research suggests eyebright lowers blood sugar on its own, so combining it with diabetes drugs raises the risk of low blood sugar. Check your specific medications with the tool on this page, and confirm the combination with your doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Eyebright is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Eyebright label
Go deeper

The Full Monographs Behind Eyebright’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eyebright

Interacts with 86 drugs

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. There is not enough reliable evidence to c...

Read the full Eyebright monograph →
Sources

Sources & How We Checked

Eyebright's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eyebright 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  4. Porchezhian, E., Ansari, S. H., and Shreedharan, N. K. Antihyperglycemic activity of Euphrasia officinale leaves. Fitoterapia 2000;71(5):522-526. PubMed

See these in context on the Eyebright monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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