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Dietary supplement

False Unicorn Root Ingredients & Drug Interactions

by Nature's Answer

False Unicorn Root label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking False Unicorn Root against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

False Unicorn Root is a dietary supplement by Nature's Answer with 1 active ingredient. Its ingredients are commonly taken for menstrual cramps, menopausal symptoms, female infertility support.Based on those ingredients, 740 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are False Unicorn Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against False Unicorn Root by Nature's Answer

Ask about any prescription or over-the-counter medication and we check it for interactions with False Unicorn Root by Nature's Answer — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of False Unicorn Root by Nature's Answer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

False Unicorn Root Extract is the single active ingredient in this liquid supplement. The extract is suspended in purified water, vegetable glycerin, and a small amount of certified organic ethyl alcohol as a preservative.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient False Unicorn product and its label doesn't state a use — see False Unicorn's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have effectiveness ratings on file for false unicorn root. Traditional use doesn't tell us whether it actually works for any particular condition, so the evidence isn't established in the data we hold.

The evidence, ingredient by ingredient False Unicorn

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

False unicorn root seems to be generally well tolerated when taken by mouth, though safety data in humans is limited. Large doses have been reported to cause nausea and vomiting, so stick to the label dose.

Because of its traditional use affecting the uterus and lack of human safety data, the safety information advises against use in pregnancy. There isn't enough safety information to recommend it while breastfeeding either.

Side effects, ingredient by ingredient False Unicorn

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — False Unicorn.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 741 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking false unicorn root, check with your pharmacist if you take any CYP2D6 substrates (antidepressants, certain pain relievers, psychiatric medications) or CYP3A4 substrates (calcium channel blockers, chemotherapy drugs) — both are Moderate-severity interactions. Also flag this if you're on lithium, which may accumulate if you add false unicorn.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a single-ingredient herbal extract with limited human safety data and no proven effectiveness in our files. If you're considering it for a specific reason, talk with your pharmacist or doctor first.

Before you start, absolutely check your medications — the enzyme interactions here can affect a wide range of drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about False Unicorn Root, straight from the product label.

Brand Nature's Answer
Barcode (UPC) 083000002861
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Jan 25, 2013
DSLD ID 16932
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for False Unicorn Root by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 mL
Maximum serving Sizes:
1 mL
Servings per container
30
UPC/BARCODE
083000002861
IngredientAmount% DV
False Unicorn Root Extract1000 mg--

Other ingredients: purified Water, Vegetable Glycerin, 12-15% certified organic Ethyl Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

ORGANIC ALCOHOL EXTRACT (1:1)

General Statements

CHAMAELIRIUM LUTEUM

Manufactured in our FDA registered and pharmaceutically licensed facility; Unconditionally guaranteed.

UNCONDITIONALLY GUARANTEED

FDA Statement of Identity

HERBAL SUPPLEMENT

FDA Disclaimer Statement

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

(Image)(R) NATURE'S ANSWER(R) Since 1972

HOLISTICALLY BALANCED(R)

K PARVE

(Image)(R) BIO-CHELATED(R) COLD EXTRACTION PROCESS

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement take 1/2-1 mL (14-28 drops) three (3) times a day in a small amount of water. - SHAKE WELL.

Precautions

KEEP OUT OF REACH OF CHILDREN

- WARNING: DO NOT USE IF PREGNANT OR NURSING

- DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING

Brand IP Statement(s)

NATURE’S ANSWER(R) organic alcohol extracts are produced using our cold Bio-Chelated(R) proprietary extraction process, yielding a Holistically Balanced(R) extract in the same synergistic ratios as in the plant.

General

9236 Rev. 5/12

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

False Unicorn Root by Nature's Answer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

False Unicorn Root label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in False Unicorn Root by Nature's Answer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

False Unicorn Root Extract

Interacts with
740 drugs
1000 mg per serving

False Unicorn is a North American plant whose root has long been used in traditional medicine for women's reproductive and menstrual concerns. There i...

False Unicorn Root Extract monograph & interactions

Other (inactive) ingredients: Purified Water, Vegetable Glycerin, 12-15% certified organic Ethyl Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

False Unicorn Root by Nature's Answer Drug Interactions

Want to check YOUR meds against False Unicorn Root?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
740Drugs
740 Moderate

Ingredients driving the most interactions

False Unicorn Root Extract 740

Individual Drug Interactions

The ingredients in False Unicorn Root interact with 740 drugs. Click any drug to see the details.

1 of the 1 ingredient in False Unicorn Root interact with drugs. Each result below shows which ingredient is responsible. False Unicorn Root Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in False Unicorn Root with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

False Unicorn Root Extract3 drug types · 740 drugs

Cytochrome P450 2D6 (Cyp2D6) Substrates

In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity. Theoretically, false unicorn might increase the levels of CYP2D6 substrates. Some of drugs that are CYP2D6 substrates include amitriptyline (Elavil), clozapine (Clozaril), codeine, desipramine (Norpramin), donepezil (Aricept), fentanyl (Duragesic), flecainide (Tambocor), fluoxetine (Prozac), meperidine (Demerol), methadone (Dolophine), metoprolol (Lopressor, Toprol XL), olanzapine (Zyprexa), ondansetron (Zofran), tramadol (Ultram), trazodone (Desyrel), and others.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity. Theoretically, false unicorn might increase the levels of CYP3A4 substrates. Drugs that might be affected include some calcium channel blockers (diltiazem, nicardipine, verapamil), chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), glucocorticoids, cisapride (Propulsid), alfentanil (Alfenta), fentanyl (Sublimaze), losartan (Cozaar), fluoxetine (Prozac), midazolam (Versed), omeprazole (Prilosec), ondansetron (Zofran), propranolol (Inderal), fexofenadine (Allegra), and numerous others.

Likelihood Possible Evidence D
Lithium

False unicorn is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, false unicorn might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
False Unicorn Root Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for False Unicorn Root, from the product label.

Nature's Answer

See all Nature's Answer products
Phone Number
(800)439-2324
Pharmacist Counseling Corner

False Unicorn Root by Nature's Answer: Common Questions

Does False Unicorn Root by Nature's Answer interact with any medications?
Yes. Based on its ingredients, False Unicorn Root has a known interaction with 740 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
False Unicorn Root contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's actually in this liquid?
It's false unicorn root extract mixed with water, vegetable glycerin, and a small amount of ethyl alcohol to keep it preserved. There's one active ingredient — the false unicorn itself.
Can I take this while pregnant?
No. Because of false unicorn's traditional use affecting the uterus and the lack of safety data in pregnancy, the safety information advises against it. Talk with your doctor if you're thinking about pregnancy or are pregnant.
Is it safe to breastfeed while using this?
The safety information says to avoid it — there isn't enough data to know it's safe while breastfeeding. Check with your doctor or pharmacist for personalized advice.
What side effects might I get?
Large doses have been reported to cause nausea and vomiting. At normal doses, it seems well tolerated, but human safety data is limited.
Does false unicorn root actually work for anything?
We don't have effectiveness ratings on file for it. Traditional use doesn't prove it works, so the evidence isn't established in our data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

False Unicorn Root label
Go deeper

The Full Monographs Behind False Unicorn Root’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

False Unicorn

Interacts with 740 drugs

False Unicorn is a North American plant whose root has long been used in traditional medicine for women's reproductive and menstrual concerns. There is very little reliable human research to...

Read the full False Unicorn monograph →
Sources

Sources & How We Checked

False Unicorn Root's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

False Unicorn 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Ho SH, Singh M, Holloway AC, Crankshaw DJ. The effects of commercial preparations of herbal supplements commonly used by women on the biotransformation of fluorogenic substrates by human cytochromes P450. Phytother Res. 2011;25(7):983-9. PubMed

See these in context on the False Unicorn monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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