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Dietary supplement

Glycine 600 Ingredients & Drug Interactions

by ProCaps Laboratories

Glycine 600 label
See full label image
Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glycine 600 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glycine 600 is a dietary supplement by ProCaps Laboratories with 1 active ingredient. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glycine 600 by ProCaps Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Glycine 600 by ProCaps Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glycine 600 by ProCaps Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Glycine 600 contains one active ingredient: glycine, a simple amino acid your body makes naturally. Each capsule delivers 600 mg.

The capsule itself is gelatin — an inactive ingredient used to hold and deliver the glycine.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Glycine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports healthy glucose metabolism and collagen.
  • We looked for evidence on: Metabolic syndrome, Obesity, Cognitive function, Wound healing, blood sugar balance, connective tissue health.
  • The closest evidence on file: Glycine is rated "Insufficient Reliable Evidence To Rate" for Cognitive function (Natural Medicines).
  • Also on file: Glycine is rated "Insufficient Reliable Evidence To Rate" for Obesity, Wound healing, Metabolic syndrome.

The evidence for glycine is mixed. For schizophrenia, the data rate it as possibly effective.

For 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, attention deficit-hyperactivity disorder (ADHD), benign prostatic hyperplasia (BPH), and cystic fibrosis, there isn't enough reliable evidence in our data to rate how well it works — more research is needed.

The evidence, ingredient by ingredient Glycine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glycine is generally well tolerated at typical doses, but long-term safety data are limited. Mild sedation has been reported rarely and goes away quickly when you stop taking it.

Some people have experienced soft stools, nausea, vomiting, or mild upper stomach discomfort — these also resolve fast if you discontinue the supplement. Irritability, insomnia, fatigue, memory impairment, headache, and dry mouth have been reported, though it's unclear whether glycine caused them.

There isn't enough reliable safety data during pregnancy and lactation. If you're pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before taking this supplement — they can help you decide whether it's right for you.

Side effects, ingredient by ingredient Glycine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glycine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take clozapine (Clozaril) for schizophrenia, talk with your doctor or pharmacist before adding this product — glycine may decrease clozapine's effectiveness and worsen symptoms. No other medication interactions are documented in our data for glycine, but that's not a guarantee none exist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Glycine 600 is a single-amino-acid supplement that's possibly effective for schizophrenia and generally well tolerated at standard doses, though long-term safety data are thin. If you take clozapine, check with your doctor before starting it — the combination may worsen schizophrenia symptoms.

For any other medications or health conditions, discuss this supplement with your own doctor or pharmacist to make sure it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glycine 600, straight from the product label.

Brand ProCaps Laboratories
Barcode (UPC) 668211
Net contents 360 Easy-To-Swallow Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 248454
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glycine 600 by ProCaps Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
360
UPC/BARCODE
668211
IngredientAmount% DV
Glycine600 mg--

Other ingredients: Gelatin Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use Consume one or more capsules daily or as recommended by your physician. As with any dietary supplement, this product is most effective as part of a healthy diet and active lifestyle, along with a daily multi-vitamin-mineral formula. For questions about the use of this product call 800.332.7799.

General Statements

HSN www.HSN.com 800.944.9999 www.QVC.com 800.345.1515

Brand IP Statement(s)

Copyright 2020 ProCaps Labs

Formulation

Protein's fundamental building block Supports healthy glucose metabolism Collagen and glutathione precursor

All-solar manufacturing

Glycine has become a popular supplement because of its role in, among other things, supporting healthy blood sugar balance and glucose metabolism. Glycine is the principal amino acid in the body's predominant protein, collagen, and therefore, plays a critical structural role in the creation of healthy skin, bones, joints, blood vessels and connective tissue (tendons, ligaments and cartilage). Glycine is also one of the three required building blocks of glutathione, which is our body's most powerful, internally produced, protective molecule. Glycine also acts as an important neurotransmitter, while also serving as a signaling molecule in the immune system. In short, despite Glycine's small size and simple structure, it plays a multitude of critical roles promoting the health of the most important systems in our body.

Contains no milk, soy, yeast, corn, wheat, gluten, sodium, salt, sugar, fat, cholesterol, color, preservative, common allergens or manufacturing additives. Contains no additives of any kind.

FDA Statement of Identity

Dietary Supplement

Formula

Andrew Lessman's Glycine 600 is a pure source of the simplest, yet uniquely important, amino acid glycine. Glycine's name results from its subtly sweet taste and the Greek word for sweet (glyks).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glycine 600 by ProCaps Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glycine 600 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glycine 600 by ProCaps Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container360 Amounts shown are per serving.

Glycine

Interacts with
1 drug
600 mg per serving

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...

Glycine monograph & interactions

Other (inactive) ingredients: Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glycine 600 by ProCaps Laboratories Drug Interactions

Want to check YOUR meds against Glycine 600?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Glycine 1

Individual Drug Interactions

The ingredients in Glycine 600 interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Glycine 600 interact with drugs. Each result below shows which ingredient is responsible. Glycine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glycine 600 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glycine1 drug type · 1 drug

Clozapine (Clozaril)

Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.

Likelihood Probable Evidence B
Glycine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glycine 600, from the product label.

ProCaps Laboratories

See all ProCaps Laboratories products
Name
ProCaps Laboratories
City
Henderson
State
NV
ZipCode
89011
Phone Number
800.800.1200
Web Address
ProCapsLabs.com
Pharmacist Counseling Corner

Glycine 600 by ProCaps Laboratories: Common Questions

Does Glycine 600 by ProCaps Laboratories interact with any medications?
Yes. Based on its ingredients, Glycine 600 has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glycine 600 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is glycine safe to take while I'm pregnant or breastfeeding?
There isn't enough reliable safety data to know. Talk with your doctor or pharmacist before taking glycine if you're pregnant, planning pregnancy, or breastfeeding — they can give you personalized advice based on your situation.
What side effects might I notice?
Mild sedation, soft stools, nausea, vomiting, or mild stomach discomfort have been reported rarely and clear up quickly if you stop taking it. Some people report irritability, insomnia, fatigue, headache, or dry mouth, though it's unclear whether glycine is the cause.
How long until glycine works?
The facts we hold don't specify how quickly you'd notice an effect. Talk with your doctor about a reasonable timeline for your particular use.
Is glycine the same as what my body makes naturally?
Glycine is an amino acid your body produces on its own. This supplement adds extra to your diet, but we don't have data on whether your body treats supplemental glycine differently from what it makes itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glycine 600 label
Go deeper

The Full Monographs Behind Glycine 600’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glycine

Interacts with 1 drug

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep quality, where early research is promisin...

Read the full Glycine monograph →
Sources

Sources & How We Checked

Glycine 600's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycine 5 references
  1. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
  2. Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
  3. Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
  4. Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
  5. Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed

See these in context on the Glycine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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