HemodrauliX Ingredients & Drug Interactions
by Axis Labs
What is this page for?
First and foremost: checking HemodrauliX against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
HemodrauliX is a dietary supplement by Axis Labs with 6 active ingredients. Its ingredients are commonly taken for heart and cholesterol health, blood pressure support, source of healthy fats and minerals.Based on those ingredients, 528 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sesame seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against HemodrauliX by Axis Labs
Ask about any prescription or over-the-counter medication and we check it for interactions with HemodrauliX by Axis Labs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of HemodrauliX by Axis Labs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
HemodrauliX contains 6 active ingredients in a softgel capsule. Beta-alanine and arginine compounds (arginine alpha-ketoglutarate and arginine ethyl ester dihydrochloride) are amino acids meant to support blood flow and muscle performance.
Arachidonic acid is a fatty acid involved in cell signaling, and sesame seed oil is included for its anti-inflammatory properties. The capsule itself is made from gelatin, glycerin, beeswax, purified water, lecithin, and titanium dioxide.
Does it work?
Moderate evidence
Beta-alanine is possibly effective for athletic performance and physical performance. The evidence for its use in age-related cognitive decline, COPD, general cognitive function, and menopausal symptoms is insufficient — we don't have enough reliable data to say whether it works for those uses.
Sesame seed oil is possibly effective for high blood pressure, possibly ineffective for cough, and has insufficient evidence for nonalcoholic fatty liver disease, HIV-related wasting, Alzheimer disease, and anemia of chronic disease. We have no effectiveness data on file for the other ingredients.
How safe is it?
Well-documented data
Beta-alanine is generally well tolerated, though it commonly causes a harmless tingling sensation (paresthesia) in the skin, usually starting on the scalp within 20 minutes and lasting about an hour — this is milder at lower doses and more pronounced at higher ones. The safety data advises against beta-alanine during pregnancy and while breastfeeding because there isn't enough information to know it's safe.
Sesame oil from food amounts is generally safe, but sesame is a major allergen — allergic reactions can include skin symptoms like swelling, redness, itching, or hives, as well as respiratory symptoms. Concentrated sesame supplements are less studied than food amounts.
One case of diarrhea was reported in a clinical trial. Safety of concentrated supplements during pregnancy and breastfeeding is not well studied, so check with your doctor.
We have no safety data on file for arachidonic acid, di-arginine malate, or arginine ethyl ester dihydrochloride.
Meds to double-check
Moderate interaction found
Before starting HemodrauliX, double-check with your doctor or pharmacist if you take blood pressure medications (antihypertensives), blood sugar medications (antidiabetes drugs), medications processed by the liver enzyme CYP2C9, tamoxifen (Nolvadex), or drugs transported by a protein called P-glycoprotein — sesame oil may affect how these work. If you have a sesame allergy, avoid this product entirely.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
HemodrauliX may appeal to you if you're looking to support athletic or physical performance through beta-alanine, but you should be cautious if you take blood pressure medication, blood sugar medication, or certain other drugs metabolized by your liver — especially if you have a sesame allergy. Talk with your doctor or pharmacist about your current medications and health before starting, and let them know if you experience tingling, skin flushing, or any allergic symptoms while taking it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about HemodrauliX, straight from the product label.
| Brand | Axis Labs |
|---|---|
| Barcode (UPC) | 689076412469 |
| Net contents | 180 Liquid Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Oct 26, 2011 |
| DSLD ID | 1064 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for HemodrauliX by Axis Labs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Beta-Alanine | 0 NP | -- |
| Arachidonic Acid | 0 NP | -- |
| Di-Arginine Malate | 0 NP | -- |
| Sesame seed Oil | 4170 mg | -- |
| Arginine Alpha-Ketoglutarate | 0 NP | -- |
| HemodrauliX Proprietary Blend | 3000 mg | -- |
| Arginine Ethyl Ester Dihydrochloride | 0 NP | -- |
Other ingredients: Kosher Gelatin, Glycerin, Beeswax, purified Water, Lecithin, Titanium Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Arachidonic Acid is protected under United States patent 6,841,573 and is licensed exclusively for use by Axis Labs(R) for HemodrauliX(TM) from Molecular Nutrition, LLC and William Llewellyn.
HemodrauliX(TM) Hemodraulix(TM) is the world’s first Nitric Oxide product to up-regulate the nitric oxide producing enzyme Nitric Oxide Synthase. This process combined with the most powerful Arginine on the planet, NE2(R) (Arginine Ethyl Ester Di-HCl) makes HemodrauliX(TM) substantially ahead of the entire Nitric Oxide category. Even Bigger Pumps, More Strength and Deeper Muscle Stimulation. Additionally, HemodrauliX(TM) combines the power of Beta-Alanine to stimulate Carnosine which reduces muscle fatigue while training. HemodrauliX(TM) feels so good, you will never want to train without it. Put your training on a faster track and start supplementing with HemodrauliX(TM) today.*
HemodrauliX(TM) is a registered trademark of Axis Labs(R).
FDA Statement of Identity
Dietary Supplement
Precautions
This product is not intended for anyone under the age of 18, pregnant or nursing. Consult your physician before using this or any dietary supplement. Do not take this product if you have any medical condition and/or are taking any prescription medication(s). Do not use if you have, or are at risk of, a myocardial infarction (heart attack), diabetes, asthma, high blood pressure, high cholesterol, arthritis, cancer, stroke, or suffering from any inflammatory diseases, or are on a red meat restricted diet. Discontinue use if experiencing any adverse side effects.
WARNING: KEEP OUT OF REACH OF CHILDREN.
Storage
Store in a cool place. Protect from heat, light and moisture.
General Statements
Anabolic Hyper-Vasodilation System With Arachidonic Acid and NE2(R) • Up-Regulates N.O. Production* • Unmatched Skin Bursting Pumps* • Deep Muscle Fiber Stimulation* • Improved Protein Synthesis* • Ignites Lipolysis (Fat into Muscles)* • Increases Bedroom Performance*
LOT
Manufactured at a FDA Inspected Facility
Manufactured with pride in the USA.
Potency and Purity GUARANTEED
int: 303-221-2110
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take 6 SoftGels 30 minutes prior to exercise. For best results, do not take more than once a day or more than 5 times a week. Supplement daily with a multivitamin while using Hemodraulix(TM).
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
HemodrauliX by Axis Labs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in HemodrauliX by Axis Labs
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size6 Liquid Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sesame seed Oil
Interacts with528 drugs
Sesame is a nutritious seed and oil widely used in cooking and traditional medicine, and it provides healthy fats, fiber, and antioxidant compounds ca...
Sesame seed Oil monograph & interactionsHemodrauliX Proprietary Blend
- › Beta-Alanine
- › Arachidonic Acid
- › Di-Arginine Malate
- › Arginine Alpha-Ketoglutarate
- › Arginine Ethyl Ester Dihydrochloride
Other (inactive) ingredients: Kosher Gelatin, Glycerin, Beeswax, Purified Water, Lecithin, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.
HemodrauliX by Axis Labs Drug Interactions
HelloPharmacist Interaction Report
HemodrauliX by Axis Labs contains sesame seed oil, which has documented interactions with several medication types.
The most serious concern is a moderate-severity interaction with blood pressure medications (antihypertensives) — sesame oil can lower blood pressure further, raising the risk of dangerously low blood pressure (hypotension).
Read the full breakdown — every affected drug type, severity by severity
Sesame oil also interacts moderately with blood sugar medications (antidiabetes drugs), potentially increasing the risk of low blood sugar (hypoglycemia), and with a class of drugs processed by the liver enzyme CYP2C9, which may raise drug levels in your body. There's also a moderate theoretical concern with tamoxifen (Nolvadex), a breast cancer medication, and a minor one with a broad group of drugs moved by a cellular transporter called P-glycoprotein.
We could not check three other ingredients in this product — arachidonic acid, di-arginine malate, and arginine ethyl ester dihydrochloride — because we don't hold interaction data for them. Altogether, these interactions span 528 individual medications.
Use the medication checker on this page to look up your exact drugs before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against HemodrauliX?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in HemodrauliX interact with 528 drugs. Click any drug to see the details.
1 of the 6 ingredients in HemodrauliX interact with drugs. Each result below shows which ingredient is responsible. Sesame seed Oil
AbrocitinibCibinqo
How Abrocitinib interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Sesame Seed Oil + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame Seed Oil + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Acebutolol interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Sesame Seed Oil + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame Seed Oil + Acetohexamide interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Sesame Seed Oil + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Sesame Seed Oil + Agomelatine interactionAlbiglutideTanzeum
How Albiglutide interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame Seed Oil + Albiglutide interactionAliskirenTekturna
How Aliskiren interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame Seed Oil + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame Seed Oil + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntidiabetes Drugs Moderate
Interaction Summary
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sesame Seed Oil + Alogliptin, Pioglitazone interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilP-glycoprotein Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, sesame might alter the transport of P-glycoprotein substrates.
Read the full Sesame Seed Oil + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Amiloride, Hydrochlorothiazide interactionAmitriptylineElavil
How Amitriptyline interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Sesame Seed Oil + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Sesame Seed Oil + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Sesame Seed Oil + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Ammonium Chloride interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Sesame Seed Oil + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilP-glycoprotein Substrates, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, sesame might alter the transport of P-glycoprotein substrates.
Read the full Sesame Seed Oil + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAprocitentanTryvio
How Aprocitentan interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilAntihypertensive Drugs Moderate
Interaction Summary
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Sesame Seed Oil + Aprocitentan interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with HemodrauliX — through 1 ingredient. Tap an ingredient for the detail:
Sesame Seed OilCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
Read the full Sesame Seed Oil + Aspirin, Omeprazole interactionEach ingredient & the kinds of drugs it affects
For each ingredient in HemodrauliX with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Sesame seed Oil
Antidiabetes Drugs
Taking sesame oil with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical studies show that sesame oil can decrease plasma glucose and glycated hemoglobin (HbA1c) levels. Some clinical research in patients taking glibenclamide shows that using sesame oil or a blend of sesame oil and rice bran oil in place of other oil for cooking reduces plasma glucose more than glibenclamide alone. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Antihypertensive Drugs
Taking sesame oil with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that replacing other cooking oil with sesame oil can lower systolic blood pressure (SBP) and diastolic blood pressure (DBP) in patients with or without hypertension. There is also some evidence that sesame oil has additive effects in patients also taking atenolol, nifedipine, and/or hydrochlorothiazide. In patients using nifedipine, using a blend of sesame oil and rice bran oil for cooking reduces both SBP and DBP more than nifedipine alone.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, sesame might increase the levels and clinical effects of CYP2C9 substrates.
In vitro, sesame inhibits CYP2C9. However, this interaction has not been reported in humans.
Tamoxifen (Nolvadex)
Theoretically, sesame might interfere with tamoxifen.
In animal research, sesame seed reduces the tumor-inhibitory effect of tamoxifen by reducing apoptosis and increasing proliferation. This interaction has not been reported in humans.
P-Glycoprotein Substrates
Theoretically, sesame might alter the transport of P-glycoprotein substrates.
In vitro research suggests that sesamin, a constituent of sesame, can inhibit the multi-drug transporter protein, P-glycoprotein. However, this interaction has not been reported in humans.
Brand information
Manufacturer and brand details for HemodrauliX, from the product label.
HemodrauliX by Axis Labs: Common Questions
Does HemodrauliX by Axis Labs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What's the tingling I might feel when I take beta-alanine?
Will this help me build muscle or improve my workout?
Is it safe to take while pregnant or breastfeeding?
Could I be allergic to this product?
What does sesame oil do in here?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if HemodrauliX is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind HemodrauliX’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sesame
Interacts with 528 drugsSesame is a nutritious seed and oil widely used in cooking and traditional medicine, and it provides healthy fats, fiber, and antioxidant compounds called lignans. Some early research sugges...
Read the full Sesame monograph → Herb & supplement monographBeta-alanine
Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...
Read the full Beta-alanine monograph →Sources & How We Checked
HemodrauliX's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 66 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Beta-alanine 13 references
- Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
- Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
- Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
- Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
- Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
- Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
- Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
- Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
- Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
- Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
- da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
- Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
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