Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

Keto-Max 3-in-1 Ingredients & Drug Interactions

by NDS

Keto-Max 3-in-1 label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Keto-Max 3-in-1 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Keto-Max 3-in-1 is a dietary supplement by NDS with 5 active ingredients. Its ingredients are commonly taken for common cold and immune support, antioxidant support, skin health and collagen formation.Based on those ingredients, 597 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin C, Chromium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Keto-Max 3-in-1 by NDS

Ask about any prescription or over-the-counter medication and we check it for interactions with Keto-Max 3-in-1 by NDS — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Keto-Max 3-in-1 by NDS

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 3 of its 9 active ingredients.
  • “Keto-Max 3-in-1 Blend” is a proprietary blend — the label gives one combined amount (880 mg) without saying how much of each component you get.
  • “Fat and Carb Blocking/Appetite Suppression Complex” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Insulin/Blood Sugar Control Complex” is a proprietary blend — the label doesn't break down how much of each component you get.

Keto-Max 3-in-1 contains 9 active and proprietary-blend ingredients. The standout actives are vitamin C (supports immune function and collagen), chromium and chromium polynicotinate (help regulate blood sugar), raspberry ketones, apple cider vinegar, chitosan (a fiber from shellfish shells often used for weight management), and vanadium — all marketed to support ketogenic dieting and carbohydrate or fat blocking.

You'll also find paraBurn, a grains-of-paradise extract. The capsule itself contains gelatin, microcrystalline cellulose, magnesium stearate, silicon dioxide, titanium dioxide, and food colorings (FD&C Red 3 and Blue 1) as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Weight management and metabolic support.
  • We looked for evidence on: Athletic performance, Chromium deficiency, Diabetes, Hypercholesterolemia, Hyperlipidemia, Appetite control — and 2 related terms.
  • The strongest evidence on file: Chromium is rated "Likely Effective" for Chromium deficiency (Natural Medicines).
  • Also on file: Chromium is rated "Possibly Effective" for Diabetes.
  • Also on file: Vitamin C is rated "Possibly Effective" for Hypercholesterolemia.

The evidence is mixed and often sparse. Vitamin C is effective for preventing C deficiency and possibly effective for anemia of chronic disease, atrial fibrillation, cataracts, and exercise-related respiratory infections.

Chromium (in both forms) is likely effective for chromium deficiency and possibly effective for diabetes, but possibly ineffective for prediabetes. Chitosan is possibly effective for obesity and blood pressure support, but evidence is insufficient for alopecia or Crohn disease.

Raspberry ketones, apple cider vinegar, vanadium, and paraBurn all lack established evidence — the data on file shows insufficient reliable evidence to rate them for their claimed uses (weight loss, cognitive or metabolic effects). If supporting ketogenic weight loss is your goal, the evidence backing most of these ingredients is not established.

The evidence, ingredient by ingredient Vitamin C Chromium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin C is generally well tolerated at normal supplement doses, but high doses (above 2 grams daily) can cause osmotic diarrhea, stomach cramps, heartburn, nausea, and in people prone to stones, kidney stones; in rare cases, very high intravenous doses have contributed to kidney failure. Chromium is usually well tolerated at typical doses but can cause gastrointestinal upset, headaches, insomnia, irritability, and mood changes; rare serious adverse effects include kidney and liver damage and thrombocytopenia (low platelets).

Raspberry ketone resembles a stimulant and case reports describe heart palpitations, elevated blood pressure, tachycardia (rapid heart rate), and in one case, a life-threatening arrhythmia. Apple cider vinegar in large or long-term amounts can cause hypokalemia (dangerously low potassium), bone loss, and topically may cause chemical burns.

Chitosan commonly causes constipation, diarrhea, nausea, and flatulence. Vanadium above the safe limit of 1.8 mg daily may cause gastrointestinal upset and at high doses long-term, kidney damage.

Pregnant women should avoid high-dose vitamin C, chitosan, vanadium, and paraBurn; chromium and apple cider vinegar data in pregnancy are limited, so discuss with your doctor. Breastfeeding safety data are similarly sparse — talk to your pharmacist before use.

Side effects, ingredient by ingredient Vitamin C Chromium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 7 matched ingredients can interact with medications — Chitosan, Vanadium, Apple Cider Vinegar, Chromium, Vitamin C, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments; diabetes medications; heart-rhythm medications.
  • For scale: 597 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check before starting if you take blood thinners (warfarin, anticoagulants, or antiplatelet drugs) — multiple ingredients may increase bleeding risk or reduce warfarin effectiveness. Check diabetes medications or insulin — chromium, apple cider vinegar, and vanadium may increase hypoglycemia risk.

Levothyroxine (thyroid): both chromium forms may reduce absorption. If you take stimulant drugs, ask your pharmacist about raspberry ketone.

Diuretics, digoxin, or any potassium-sensitive medication should be reviewed due to apple cider vinegar's hypokalemia risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product carries multiple medication interactions, especially for people taking diabetes drugs, insulin, blood thinners, thyroid medication, or stimulants. If you take any prescription medication — particularly for blood sugar, clotting, or heart rhythm — check each of your drugs with the tool on this page before starting.

Talk to your pharmacist; the ingredient evidence for weight loss is not established, and the safety profile has red flags for high doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Keto-Max 3-in-1, straight from the product label.

Brand NDS
Barcode (UPC) 811020907916
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 277206
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Keto-Max 3-in-1 by NDS, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
811020907916
IngredientAmount% DV
Vitamin C60 mg67%
Chromium200 mcg571%
Raspberry Ketones0 NP--
Apple Cider Vinegar0 NP--
Chromium Polynicotinate0 NP--
White Kidney Bean extract0 NP--
Chitosan0 NP--
Keto-Max 3-in-1 Blend880 mg--
Fat and Carb Blocking/Appetite Suppression Complex0 NP--
Insulin/Blood Sugar Control Complex0 NP--
Vanadium0 NP--
Inches/Fat Burn Compounds0 NP--
paraBurn40 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Titanium Dioxide, FD&C Red 3, FD&C Blue 1

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Take 1-2 capsules 30 minutes prior to two meals with 8 fl. oz. of juice or water. Do not exceed more than 2 servings per day. To be used as part of a healthy lifestyle consisting of regular physical activity and a proper diet.

Precautions

Warning: Keep out of reach of children.

Do not exceed recommended dose.

Not intended for use by persons under age 18.

Do not use if pregnant or lactating.

If you are under the care of a physician, please consult your physician before using this product. Do not use if tamper resistant seal is broken.

California residents Warning: Cancer and reproductive harm - www.P65Warnings.ca.gov/Food

Contains shell ingredients (Chitosan from crab/shrimp shell).

Storage

Store in a cool dry place. Avoid excessive heat.

General Statements

Consumer notice: FitLife Brands can only confirm product purity when our brands are purchased from authorized retailers on gnc.com, or on ndsnutrition.com.

Follow us @ndsnutrition: Use #ndsketomax Facebook Instagram Twitter

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Advanced carb/fat blocker

Support for: Appetite suppression Healthy blood sugar levels Metabolism boost

Stimulant free

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

paraBurn is a trademark of FitLife Brands, Inc.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Keto-Max 3-in-1 by NDS label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Keto-Max 3-in-1 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Keto-Max 3-in-1 by NDS

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin C

Interacts with
207 drugs
60 mg per serving Form: Ascorbic Acid

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...

Vitamin C monograph & interactions

Chromium

Interacts with
178 drugs
200 mcg per serving Form: Chromium Polynicotinate

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

Keto-Max 3-in-1 Blend

880 mg per serving
  • › Fat and Carb Blocking/Appetite Suppression Complex
  • › Insulin/Blood Sugar Control Complex
  • › Inches/Fat Burn Compounds

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Titanium Dioxide, FD&C Red 3, FD&C Blue 1. These complete the product’s ingredient list but are not active constituents.

Interaction report

Keto-Max 3-in-1 by NDS Drug Interactions

Want to check YOUR meds against Keto-Max 3-in-1?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
597Drugs
533 Moderate 64 Minor

Ingredients driving the most interactions

Vitamin C 207
Chromium 178

Individual Drug Interactions

The ingredients in Keto-Max 3-in-1 interact with 597 drugs. Click any drug to see the details.

2 of the 5 ingredients in Keto-Max 3-in-1 interact with drugs. Each result below shows which ingredient is responsible. Vitamin C Chromium

Each ingredient & the kinds of drugs it affects

For each ingredient in Keto-Max 3-in-1 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin C13 drug types · 207 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Aluminum

Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.

Likelihood Probable Evidence B
Antitumor Antibiotics

Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Estrogens

Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.

Likelihood Probable Evidence B
Fluphenazine (Prolixin)

Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.

Likelihood Possible Evidence D
Indinavir (Crixivan)

Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.

Likelihood Probable Evidence B
Warfarin (Coumadin)

High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.

Likelihood Probable Evidence B
Aspirin

Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.

Likelihood Possible Evidence B
Choline Magnesium Trisalicylate (Trilisate)

Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Niacin

Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Salsalate (Disalcid)

Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Vitamin C full monograph & interactions

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Keto-Max 3-in-1, from the product label.

NDS

See all NDS products
Name
FitLife Brands, Inc.
Street Address
5214 South 136th Street
City
Omaha
State
NE
ZipCode
68137
Web Address
NDSNutrition.com
Pharmacist Counseling Corner

Keto-Max 3-in-1 by NDS: Common Questions

Does Keto-Max 3-in-1 by NDS interact with any medications?
Yes. Based on its ingredients, Keto-Max 3-in-1 has a known interaction with 597 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Keto-Max 3-in-1 contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me lose weight on a keto diet?
The evidence is not established for most ingredients. Chitosan is possibly effective for obesity, and chromium is possibly effective for diabetes — but raspberry ketone, apple cider vinegar, and the proprietary blends lack reliable evidence to support weight loss claims. Your results will depend on your diet and exercise, not the supplement alone.
Is it safe to take if I'm on birth control?
Vitamin C in this product can increase estrogen levels from oral contraceptives by up to 55% in some cases, which may affect how well your birth control works or raise side effects like headaches or nausea. Talk to your doctor or pharmacist about whether this product is right for you.
What are the most common side effects?
Vitamin C and chromium may cause stomach cramps, diarrhea, headaches, and nausea. Chitosan often causes constipation, diarrhea, or bloating. Raspberry ketone case reports mention heart palpitations and sweating. Higher doses of any ingredient increase the risk of side effects.
Can I take this while pregnant or breastfeeding?
No, not without talking to your doctor first. High-dose vitamin C, chitosan, vanadium, and paraBurn advise against use; chromium and apple cider vinegar have limited pregnancy safety data. Breastfeeding safety is unknown for most ingredients. Your doctor can help you decide if this is right for you.
Does this product have fillers?
Yes. The capsule contains gelatin, microcrystalline cellulose, magnesium stearate, silicon dioxide, titanium dioxide, and two food colorings (FD&C Red 3 and Blue 1). If you're allergic to any of these or shellfish (chitosan is derived from shellfish), let your pharmacist know.
What's in the 'blends' listed on the label?
The three proprietary blends — Keto-Max 3-in-1 Blend, Fat and Carb Blocking/Appetite Suppression Complex, and Insulin/Blood Sugar Control Complex — contain the individual ingredients already listed separately (vitamin C, chromium, apple cider vinegar, chitosan, raspberry ketone, vanadium, and paraBurn). The manufacturer does not break down the dose of each ingredient within the blends.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Keto-Max 3-in-1 label
Go deeper

The Full Monographs Behind Keto-Max 3-in-1’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin C

Interacts with 207 drugs

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...

Read the full Vitamin C monograph → Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph →
Sources

Sources & How We Checked

Keto-Max 3-in-1's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 153 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin C 51 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
  3. Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
  4. Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
  5. Dwyer JH, Merz NB, Shirocre AM, et al. Progression of early atherosclerosis and intake of vitamin C and vitamin E from supplements and food. The Los Angeles Atherosclerosis Study. 41st Annual Conference on Cardiovascular Disease Epidemiology and Prevent
  6. Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-23. PubMed
  7. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  8. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  9. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
  10. Houston JB, Levy G. Drug biotransformation interactions in man VI: Acetaminophen and ascorbic acid. J Pharm Sci 1976;65:1218-21. PubMed
  11. Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
  12. Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671. DOI
  13. Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479. DOI
  14. Smith EC, Skalski RJ, Johnson GC, Rossi GV. Interaction of ascorbic acid and warfarin. JAMA 1972;221:1166. DOI
  15. Traxer O, Huet B, Poindexter J, et al. Effect of ascorbic acid consumption on urinary stone risk factors. J Urol 2003;170:397-401.. PubMed
  16. Domingo JL, Gomez M, Llobet JM, Richart C. Effect of ascorbic acid on gastrointestinal aluminum absorption (letter). Lancet 1991;338:1467.
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Raspberry Ketone 4 references
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See these in context on the Raspberry Ketone monograph →

Apple Cider Vinegar 11 references
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Chitosan 17 references
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See these in context on the Chitosan monograph →

Vanadium 15 references
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See these in context on the Vanadium monograph →

Grains Of Paradise 2 references
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source

See these in context on the Grains Of Paradise monograph →

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© 2021 Therapeutic Research Center, LLC

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