Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Lutein Ingredients & Drug Interactions

by Bronson

Lutein label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lutein against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lutein is a dietary supplement by Bronson with 2 active ingredients. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Spinach. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Lutein by Bronson

Ask about any prescription or over-the-counter medication and we check it for interactions with Lutein by Bronson — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Lutein by Bronson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: lutein and spinach extract. Lutein is a yellow pigment found in leafy greens and is concentrated in the macula, the part of your eye responsible for sharp central vision.

Spinach is included as a natural source of lutein and other plant compounds. The capsule also contains inactive ingredients — white rice powder, gelatin, magnesium stearate, and silicon dioxide — which are used as fillers and binders to hold the supplement together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: helps maintain healthy eyes.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Diabetic retinopathy, Dry eye, Glaucoma — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Lutein is rated "Possibly Ineffective" for Retinitis pigmentosa, Retinopathy of prematurity.

Lutein is possibly effective for age-related macular degeneration (AMD) and cataracts — two common eye conditions. The evidence is promising but not yet conclusive.

For retinitis pigmentosa, retinopathy of prematurity, necrotizing enterocolitis, and bronchopulmonary dysplasia, lutein appears possibly ineffective. Spinach's effectiveness for cognitive function, muscle strength, obesity, PCOS, and fatty liver disease hasn't been established in the data we hold — the evidence is either too limited or too mixed to rate it one way or the other.

The evidence, ingredient by ingredient Lutein Spinach

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein from food and typical supplement doses is well tolerated. Doses up to 20 mg daily haven't caused adverse effects in studies.

However, there isn't enough research on higher supplement doses, so use caution and talk with your doctor about the right dose for you. Spinach as food is safe during pregnancy and breastfeeding.

Lutein is naturally present in breast milk, but the safety of higher supplement doses during breastfeeding isn't well studied, so check with your doctor or pharmacist. Very rare: in infants under 4 months, spinach has been associated with a condition called methemoglobinemia, which is why this product isn't appropriate for babies.

Side effects, ingredient by ingredient Lutein Spinach

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Spinach.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking if you use warfarin or another blood thinner (Moderate interaction): spinach's vitamin K can interfere with how these drugs work and may require a dose adjustment. Also double-check if you take diabetes medication (Moderate interaction): spinach may lower blood glucose levels and increase the risk of hypoglycemia.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have AMD or cataracts and don't take a blood thinner or diabetes medication, this supplement may be worth trying — the evidence leans toward benefit. If you take warfarin, a diabetes drug, or any other prescription medication, run it through the checker on this page first, or talk with your pharmacist before you start.

Pregnancy and breastfeeding are likely safe, but confirm the right dose with your doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 1, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein, straight from the product label.

Brand Bronson
Barcode (UPC) 716563191016
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jun 1, 2012
DSLD ID 8873
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein by Bronson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
716563191016
IngredientAmount% DV
Lutein6 mg--
Spinach50 mg--

Other ingredients: White rice powder, Gelatin, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

EXP 08/2013 1107222

Made in USA

HELPS MAINTAIN HEALTHY EYES

Precautions

Keep out of reach of children.

WARNING: Please consult a healthcare professional before taking this product if you are pregnant or nursing.

Storage

Store at room temperature. Protect from light.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

No. 191 REF 0610

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

DIRECTIONS: As a dietary supplement for adults, 1 capsule one to two times daily or as directed by a health professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lutein by Bronson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lutein label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lutein by Bronson

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lutein

No known
interactions
6 mg per serving

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Spinach

Interacts with
88 drugs
50 mg per serving

Spinach is a nutrient-dense leafy green that is a healthy part of a balanced diet, providing vitamins, minerals, fiber, and antioxidants. While it is...

Spinach monograph & interactions

Other (inactive) ingredients: White rice powder, Gelatin, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein by Bronson Drug Interactions

Want to check YOUR meds against Lutein?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
88Drugs
88 Moderate

Ingredients driving the most interactions

Spinach 88

Individual Drug Interactions

The ingredients in Lutein interact with 88 drugs. Click any drug to see the details.

1 of the 2 ingredients in Lutein interact with drugs. Each result below shows which ingredient is responsible. Spinach

Each ingredient & the kinds of drugs it affects

For each ingredient in Lutein with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Spinach2 drug types · 88 drugs

Antidiabetes Drugs

There are claims that spinach leaves have hypoglycemic effects. Evidence from clinical research suggests that consumption of a spinach-rich meal reduces post-meal blood glucose levels. Theoretically, spinach might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Monitor blood glucose levels closely. Dose adjustments might be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Spinach contains vitamin K, which can interfere with the activity of warfarin.
In human research, although eating spinach with one meal does not result in coagulation test results outside the therapeutic range, daily consumption for one week necessitates dose adjustment of warfarin. Individuals using anticoagulants should consume a consistent daily amount of spinach to maintain the effect of anticoagulant therapy.

Likelihood Possible Evidence D
Spinach full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lutein, from the product label.

Bronson

Name
Bronson Laboratories
City
Lindon
State
UT
ZipCode
84042
Pharmacist Counseling Corner

Lutein by Bronson: Common Questions

Does Lutein by Bronson interact with any medications?
Yes. Based on its ingredients, Lutein has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lutein contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my vision or prevent cataracts?
Lutein is possibly effective for both age-related macular degeneration and cataracts, meaning the evidence suggests it may help, but it's not proven yet. Talk with your doctor about whether it makes sense for your situation.
Is lutein safe at the doses in this supplement?
Yes. Lutein from foods and typical supplement doses is well tolerated, and studies show doses up to 20 mg daily haven't caused adverse effects. However, research on higher supplement doses is limited, so discuss the right dose with your doctor.
Can I take this while pregnant or breastfeeding?
Lutein is likely safe during pregnancy and breastfeeding. Spinach is safe as food during both. However, research on higher supplement doses while breastfeeding isn't complete, so check with your doctor or pharmacist about the dose that's right for you. Do not give this to infants under 4 months old.
What exactly is in this, and are there fillers?
It contains two active ingredients — lutein and spinach — plus four inactive ingredients (white rice powder, gelatin, magnesium stearate, and silicon dioxide) that help hold the capsule together.
I take warfarin. Can I take this supplement?
Warfarin requires caution with this product because spinach contains vitamin K, which interferes with how warfarin works. Eating spinach once isn't usually a problem, but daily use may require a warfarin dose adjustment. Talk with your doctor before starting this supplement.
I have diabetes. Is this safe for me?
There's evidence that spinach can lower blood glucose levels after meals. Combined with your diabetes medication, this could increase the risk of low blood sugar. Talk with your doctor before taking this, and if you do, monitor your blood glucose closely.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lutein is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein label
Go deeper

The Full Monographs Behind Lutein’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph → Herb & supplement monograph

Spinach

Interacts with 88 drugs

Spinach is a nutrient-dense leafy green that is a healthy part of a balanced diet, providing vitamins, minerals, fiber, and antioxidants. While it is very safe as a food, concentrated supple...

Read the full Spinach monograph →
Sources

Sources & How We Checked

Lutein's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Spinach 6 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Karlson, B., Leijd, B., and Hellstrom, K. On the influence of vitamin K-rich vegetables and wine on the effectiveness of warfarin treatment. Acta Med Scand. 1986;220(4):347-350. PubMed
  3. Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.
  4. Schuller, A., Morisset, M., Maadi, F., Kolopp Sarda, M. N., Fremont, S., Parisot, L., Kanny, G., and Moneret-Vautrin, D. A. Occupational asthma due to allergy to spinach powder in a pasta factory. Allergy 2005;60(3):408-409. PubMed
  5. Gustafsson, K., Asp, N. G., Hagander, B., and Nyman, M. Satiety effects of spinach in mixed meals: comparison with other vegetables. Int.J.Food Sci.Nutr. 1995;46(4):327-334. PubMed
  6. Schreiber, J., Muller, E., Becker, W. M., Zabel, P., Schlaak, M., and Amthor, M. [Spinach powder-induced exogenous allergic alveolitis]. Pneumologie 1998;52(1):61-65.

See these in context on the Spinach monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team