Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

MemorEase Ingredients & Drug Interactions

by Lidtke

MemorEase label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking MemorEase against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

MemorEase is a dietary supplement by Lidtke with 3 active ingredients. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Phosphatidylserine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against MemorEase by Lidtke

Ask about any prescription or over-the-counter medication and we check it for interactions with MemorEase by Lidtke — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of MemorEase by Lidtke

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (25 mg) without saying how much of each component you get.

MemorEase has 3 active ingredients. Phosphatidylcholine and phosphatidylserine are naturally occurring compounds found in cell membranes; they're thought to support brain function and memory.

Phosphatidylethanolamine is another membrane component we couldn't evaluate for interaction data. The softgel also contains gelatin, glycerin, purified water, and polyglycitol syrup as inactive ingredients to hold the formula together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: memory, attention and brain health support.
  • We looked for evidence on: Age-related cognitive decline, Memory, Cognitive function, Attention deficit-hyperactivity disorder (ADHD), Dementia, Alzheimer disease — and 4 related terms.
  • The strongest evidence on file: Phosphatidylserine is rated "Possibly Effective" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Phosphatidylserine is rated "Possibly Effective" for Alzheimer disease.
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Memory, Dementia, Aging.

Evidence is mixed and modest for most claims on this product. Phosphatidylserine shows possibly effective evidence for age-related cognitive decline and Alzheimer disease — meaning some studies suggest it may help, but more research is needed.

Phosphatidylcholine is possibly effective for ulcerative colitis, though it isn't labeled for that use here. For other purposes listed — Alzheimer disease, anxiety, ADHD, dementia, athletic performance, and general cognitive function — the evidence we hold is insufficient to say whether it works.

Talk with your doctor about what you're hoping to improve, and whether the evidence fits your needs.

The evidence, ingredient by ingredient Phosphatidylcholine Phosphatidylserine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both phosphatidylcholine and phosphatidylserine are generally well tolerated at typical doses. The most common side effects are mild: bloating, diarrhea, nausea, altered taste, flatulence, headache, and insomnia.

Very high doses of phosphatidylcholine (30 grams per day or more) can cause digestive upset; phosphatidylserine at 600 mg or higher may cause insomnia. For pregnancy, safety data is incomplete — choline (in phosphatidylcholine) is needed during pregnancy, but supplement safety beyond food sources isn't well studied.

Phosphatidylserine should be avoided in pregnancy due to insufficient safety information. Breastfeeding safety isn't established for either ingredient.

Talk with your doctor or pharmacist before taking MemorEase if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Phosphatidylcholine Phosphatidylserine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Phosphatidylserine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before starting MemorEase if you take anticholinergic drugs (moderate concern) or cholinergic drugs (moderate concern). These interactions are theoretically based, but your doctor or pharmacist should review them against your specific medications and medical history.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

MemorEase may be worth considering if you're interested in supporting memory and brain health, especially age-related cognitive changes, and you're not taking anticholinergic or cholinergic medications. If you take any prescription drugs — particularly for bladder control, Parkinson disease, myasthenia gravis, or Alzheimer disease — check with your own doctor or pharmacist before starting.

The same goes if you're pregnant, breastfeeding, or planning to become pregnant.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MemorEase, straight from the product label.

Brand Lidtke
Barcode (UPC) 630610003247
Net contents 60 Soft Gel(s)
Market status On market
Date entered into DSLD Dec 18, 2021
DSLD ID 257233
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MemorEase by Lidtke, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gelcap(s)
Maximum serving Sizes:
1 Gelcap(s)
Servings per container
60
UPC/BARCODE
630610003247
IngredientAmount% DV
Phosphatidylcholine0 NP--
Phosphatidylethanolamine0 NP--
Proprietary Blend25 mg--
Phosphatidylserine100 mg--

Other ingredients: Gelatin, Glycerin, purified Water, Polyglycitol Syrup

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Thank you for choosing MemorEase by Lidtke. We sincerely wish the best of health for you and your family.

Lidtke stands behind each product and guarantees customer satisfaction for 365 days from the date of purchase.

Formula

Lidtke MemorEase is the Sharp PS enhanced-stability phosphatidylserine (PS) soft gel with fluid dispersion for maximum brain benefits.

Made from sunflower

Formulation

Without sufficient levels of PS, brain cells do not transmit nerve impulses properly. PS helps slow age-related cognitive decline, promoting better memory, attention and concentration.

Non-GMO. No added gluten, yeast, wheat, soy, milk, eggs, nuts, fish, shellfish, sugar, preservatives, artificial color or flavor.

Purest on the planet

Promotes clear thinking & sharp memory Helps concentration

Soy Free Non-GMO

Superb quality since 1994

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Keep out of reach of children.

If you are pregnant, lactating, taking any medications or have a medical condition, consult your doctor.

Discontinue use if adverse reaction occurs. Do not use if seal is damaged or missing.

Adverse events may be reported above.

Storage

Keep lid tightly closed. Keep in a cool, dry place.

FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions (Adults): Take one (1) soft gel with meals (three per day) or as directed by a health-care professional.

Seals/Symbols

GMP

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

MemorEase by Lidtke label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

MemorEase label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in MemorEase by Lidtke

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Gelcap(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

25 mg per serving

Phosphatidylserine

Interacts with
219 drugs
100 mg per serving Form: Sunflower

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...

Phosphatidylserine monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Purified Water, Polyglycitol Syrup. These complete the product’s ingredient list but are not active constituents.

Interaction report

MemorEase by Lidtke Drug Interactions

Want to check YOUR meds against MemorEase?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
219Drugs
219 Moderate

Ingredients driving the most interactions

Phosphatidylserine 219

Individual Drug Interactions

The ingredients in MemorEase interact with 219 drugs. Click any drug to see the details.

1 of the 3 ingredients in MemorEase interact with drugs. Each result below shows which ingredient is responsible. Phosphatidylserine

Each ingredient & the kinds of drugs it affects

For each ingredient in MemorEase with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Phosphatidylserine2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.

Likelihood Possible Evidence B
Cholinergic Drugs

Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence B
Phosphatidylserine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for MemorEase, from the product label.

Lidtke

See all Lidtke products
Name
Lidtke Technologies
City
Chandler
State
AZ
ZipCode
85226
Phone Number
1-800-404-8185
Web Address
www.lidtke.com
Pharmacist Counseling Corner

MemorEase by Lidtke: Common Questions

Does MemorEase by Lidtke interact with any medications?
Yes. Based on its ingredients, MemorEase has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
MemorEase contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take MemorEase if I'm pregnant or breastfeeding?
The safety data advises against phosphatidylserine during pregnancy, so you should not take MemorEase if you're pregnant. For breastfeeding, there isn't enough data to know either way, and phosphatidylcholine safety beyond food sources while breastfeeding is also unclear. Talk with your doctor or pharmacist before taking it if you're pregnant, breastfeeding, or planning to become pregnant.
What side effects might I notice?
Most people experience no side effects or only mild ones: bloating, diarrhea, nausea, altered taste, flatulence, headache, or insomnia. These are more likely at higher doses — insomnia risk rises with 600 mg or more of phosphatidylserine. Digestive upset can show up at doses as low as 200–300 mg per day for some people.
Does MemorEase actually work for memory and cognitive decline?
Phosphatidylserine shows possibly effective evidence for age-related cognitive decline and Alzheimer disease, meaning some research suggests it may help, but we don't have strong proof yet. For other brain-related uses — ADHD, general cognitive function, dementia, anxiety — the evidence we hold is insufficient to say whether it works.
What are phosphatidylcholine and phosphatidylserine?
Both are naturally occurring compounds found in your cell membranes. They're thought to support brain cell structure and function. Phosphatidylcholine is possibly effective for ulcerative colitis, while phosphatidylserine has modest evidence in age-related memory loss.
Is there an ingredient in MemorEase you couldn't check for drug interactions?
Yes — phosphatidylethanolamine. We hold no interaction data for that ingredient, so we couldn't evaluate it against your medications. Use the search tool on this page to check your exact drugs against all the documented interactions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MemorEase label
Go deeper

The Full Monographs Behind MemorEase’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Phosphatidylcholine

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, but solid human evidence is limited for mo...

Read the full Phosphatidylcholine monograph → Herb & supplement monograph

Phosphatidylserine

Interacts with 219 drugs

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinking. Some research suggests possible bene...

Read the full Phosphatidylserine monograph →
Sources

Sources & How We Checked

MemorEase's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Phosphatidylserine 9 references
  1. Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
  2. Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
  3. Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
  4. Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
  5. Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
  6. Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
  7. Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
  8. Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
  9. Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed

See these in context on the Phosphatidylserine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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