Interactions on record — worth a quick check against your medications. Based on 7 of 11 ingredients. Check your meds →
Dietary supplement

Plant Enzymes Ingredients & Drug Interactions

by Innate Response Formulas

Plant Enzymes label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Plant Enzymes against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Plant Enzymes is a dietary supplement by Innate Response Formulas with 11 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 2,260 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow, Ginger, Astragalus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Plant Enzymes by Innate Response Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Plant Enzymes by Innate Response Formulas — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Plant Enzymes by Innate Response Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 11 of its 11 active ingredients.
  • “Probiotic” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Plant Enzyme” is listed as a grouped ingredient — the label gives one combined amount (107 mg) without saying how much of each component you get.
  • “Botanicals” is listed as a grouped ingredient — the label gives one combined amount (150 mg) without saying how much of each component you get.

Plant Enzymes contains 11 active ingredients: amylase, lipase, lactase, cellulase, invertase, ginger, glucoamylase, protease (labeled Protease 4.5), astragalus, marshmallow, and Lactobacillus acidophilus (a probiotic strain). The enzymes — amylase, lipase, lactase, cellulase, invertase, and glucoamylase — are meant to help break down different food components (carbohydrates, fats, lactose, plant fiber, and sugars, respectively).

Protease breaks down proteins. Ginger and marshmallow are traditional plant ingredients, and astragalus is an herb used in herbal medicine.

Lactobacillus acidophilus is a friendly bacterium. The product also contains one inactive ingredient: plant fiber.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Lactose intolerance — rated "Effective" (Lactase) (Natural Medicines).
  • On file: Antibiotic-associated diarrhea — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Bacterial vaginosis — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Helicobacter pylori — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Irritable bowel syndrome (IBS) — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).

The evidence on these ingredients is limited. Lactase is effective for lactose intolerance.

Ginger appears possibly effective for pregnancy-related nausea and dysmenorrhea (period pain), and possibly effective for osteoarthritis, but appears possibly ineffective for exercise-induced muscle soreness and chemotherapy-related nausea. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

For the remaining active ingredients — amylase, lipase, cellulase, invertase, glucoamylase, protease, astragalus, and marshmallow — the evidence we hold shows insufficient reliable evidence to rate their effectiveness for the conditions studied, or no effectiveness data is available.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Lipase Lactase Proteolytic Enzymes (proteases) Ginger Astragalus Marshmallow

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase and lactase are generally well tolerated; lactase is likely safe in pregnancy. Ginger is generally well tolerated in typical amounts but increases side effects at doses above 5 grams per day — common mild effects include heartburn, burping, diarrhea, and mouth irritation.

Ginger is likely safe in pregnancy but check with your doctor first. Protease is generally well tolerated but safety in pregnancy has not been established, so it should be avoided during pregnancy.

Astragalus is generally well tolerated short-term in healthy adults, but safety data are limited; it should be avoided during pregnancy and breastfeeding. Marshmallow is generally well tolerated short-term but should be avoided during pregnancy and breastfeeding.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children; it may occasionally cause mild digestive upset (abdominal discomfort, bloating, flatulence, diarrhea). Rare but serious infections (such as sepsis or endocarditis) have been reported with L. acidophilus in certain patient groups, though this is uncommon in healthy individuals.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Lipase Lactase Proteolytic Enzymes (proteases) Ginger Astragalus Marshmallow

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 7 matched ingredients can interact with medications — Marshmallow, Lactobacillus Acidophilus, Ginger, Astragalus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 2,261 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (warfarin, phenprocoumon, aspirin, clopidogrel), diabetes medications, blood pressure drugs (especially losartan or nifedipine), lithium, immunosuppressants, cancer medications processed through CYP3A4, certain heart drugs processed through P-glycoprotein, or antibiotics. Ginger, astragalus, and marshmallow each carry Moderate interactions with some of these categories, and Lactobacillus acidophilus can interfere with antibiotic effectiveness.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may appeal to people looking for digestive enzyme support or interested in ginger's effects on nausea and joint comfort, combined with probiotic benefits. However, anyone taking blood thinners, diabetes medications, heart medications, lithium, immunosuppressants, or antibiotics should clear this product with their doctor or pharmacist first — the interactions are real and may affect how your medications work.

Talk with your healthcare provider about whether Plant Enzymes fits your individual situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Plant Enzymes, straight from the product label.

Brand Innate Response Formulas
Barcode (UPC) 051494400852
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2013
DSLD ID 24526
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Plant Enzymes by Innate Response Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
051494400852
IngredientAmount% DV
Amylase4000 DU--
Lipase200 FIP--
Lactase400 ALU--
Cellulase100 CU--
Invertase50 SU--
Ginger30 mg--
Glucoamylase4.5 AGU--
Protease 4.515000 HUT--
Astragalus45 mg--
Marshmallow75 mg--
Probiotic0 NP--
Plant Enzyme107 mg--
Lactobacillus acidophilus100000000 CFU--
Botanicals150 mg--

Other ingredients: Plant Fiber

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Made in USA

603-216-0899

Vis medicatrix naturae

100% WHOLE FOOD

Clinical Strength - Professional Use Only

EXCEPTIONALLY PURE 100% WHOLE FOOD NUTRIENTS

- Vegetarian Capsule - Supports Gluten Free Diets - Promotes Digestion of All Foods

- GMP Compliant

FDA Statement of Identity

Dietary Supplement

General

Product Code #40085 F3719B-10 Rev: 8 4/09

Suggested/Recommended/Usage/Directions

Suggested Use: 1 or more capsules with meals as needed, or as recommended by your healthcare practitioner.

Formulation

Does not contain Sugar, Dairy or Gelatin

Free of Herbicides, Pesticides & Corn

- Nothing Artificial or Synthetic - Tested Free of Gluten, Dairy and Soy

- Suitable for Vegetarians

Seals/Symbols

Please Recycle

Broad Spectrum Multi-Component Finished Good Tested

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Plant Enzymes by Innate Response Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Plant Enzymes label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Plant Enzymes by Innate Response Formulas

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Probiotic

Interacts with
182 drugs
0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Probiotic monograph & interactions

Plant Enzyme

107 mg per serving

Botanicals

150 mg per serving

Other (inactive) ingredients: Plant Fiber. These complete the product’s ingredient list but are not active constituents.

Interaction report

Plant Enzymes by Innate Response Formulas Drug Interactions

Want to check YOUR meds against Plant Enzymes?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,260Drugs
1,108 Moderate 1,152 Minor

Ingredients driving the most interactions

Marshmallow 2,040
Ginger 1,007
Astragalus 208
Probiotic 182

Individual Drug Interactions

The ingredients in Plant Enzymes interact with 2,260 drugs. Click any drug to see the details.

4 of the 11 ingredients in Plant Enzymes interact with drugs. Each result below shows which ingredient is responsible. Marshmallow Ginger Astragalus Probiotic

Each ingredient & the kinds of drugs it affects

For each ingredient in Plant Enzymes with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Marshmallow3 drug types · 2,040 drugs

Lithium

Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.

Likelihood Possible Evidence D
Marshmallow full monograph & interactions

Ginger14 drug types · 1,007 drugs

Anticoagulant/Antiplatelet Drugs

Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, research is conflicting.
Laboratory research suggests that ginger inhibits thromboxane synthetase and decreases platelet aggregation. However, this has not been demonstrated unequivocally in humans, with mixed results from clinical trials. Theoretically, excessive amounts of ginger might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Animal and human research suggests that ginger might increase insulin levels and/or decrease blood glucose levels.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Ginger might increase or decrease the levels of CYP3A4 substrates.
In vitro research and some case reports suggest that ginger inhibits CYP3A4 activity. Three case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are CYP3A4 substrates (imatinib, dabrafenib, and crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Conversely, other in vitro research suggests that ginger induces CYP3A4 activity, leading to reduced levels of CYP3A4 substrates. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Losartan (Cozaar)

Theoretically, ginger might increase levels of losartan and the risk of hypotension.
In animal research, ginger increased the levels and hypotensive effects of a single dose of losartan. It is not clear if ginger alters the concentration or effects of losartan when taken continuously. Additionally, this interaction has not been shown in humans.

Likelihood Possible Evidence D
Nifedipine (Procardia)

Ginger may have antiplatelet effects and increase the risk of bleeding if used with nifedipine.
Clinical research shows that combined treatment with ginger 1 gram plus nifedipine 10 mg significantly inhibits platelet aggregation when compared to nifedipine or ginger alone.

Likelihood Possible Evidence B
P-Glycoprotein Substrates

Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
In vitro research and case reports suggest that ginger inhibits drug efflux by P-gp, potentially increasing absorption and serum levels of P-gp substrates. Two case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are P-gp substrates (trametinib, crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.

Likelihood Possible Evidence D
Phenprocoumon (Marcoumar, Others)

Ginger might increase the risk of bleeding with phenprocoumon.
Phenprocoumon, a warfarin-related anticoagulant, might increase the international normalized ratio (INR) when taken with ginger. There is one case report of a 76-year-old woman with a stable INR on phenprocoumon that increased to greater than 10 when she began consuming dried ginger and ginger tea.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Ginger might increase the risk of bleeding with warfarin.
Laboratory research suggests that ginger might inhibit thromboxane synthetase and decrease platelet aggregation. In one case report, ginger increased the INR when taken with phenprocoumon, which has similar pharmacological effects as warfarin. In another case report, ginger increased the INR when taken with a combination of warfarin, hydrochlorothiazide, and acetaminophen. A longitudinal analysis suggests that taking ginger increases the risk of bleeding in patients taking warfarin for at least 4 months. However, research in healthy people suggests that ginger has no effect on INR, or the pharmacokinetics or pharmacodynamics of warfarin. Until more is known, monitor INRs closely in patients taking large amounts of ginger.

Likelihood Possible Evidence B
Calcium Channel Blockers

Theoretically, taking ginger with calcium channel blockers might increase the risk of hypotension.
Some animal and in vitro research suggests that ginger has hypotensive and calcium channel-blocking effects. Another animal study shows that concomitant administration of ginger and the calcium channel blocker amlodipine leads to greater reductions in blood pressure when compared with amlodipine alone.

Likelihood Unlikely Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, when taken prior to cyclosporine, ginger might decrease cyclosporine levels.
In an animal model, ginger juice taken 2 hours prior to cyclosporine administration reduced the maximum concentration and area under the curve of cyclosporine by 51% and 40%, respectively. This effect was not observed when ginger juice and cyclosporine were administered at the same time.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ginger might increase the levels of CYP1A2 substrates.
In vitro research shows that ginger inhibits CYP1A2 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, ginger might increase the levels of CYP2B6 substrates.
In vitro research shows that ginger inhibits CYP2B6 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, ginger might increase the levels of CYP2C9 substrates.
In vitro research shows that ginger inhibits CYP2C9 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Metronidazole (Flagyl)

Theoretically, ginger might increase levels of metronidazole.
In an animal model, ginger increased the absorption and plasma half-life of metronidazole. In addition, the elimination rate and clearance of metronidazole was significantly reduced.

Likelihood Possible Evidence D
Ginger full monograph & interactions

Astragalus4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
Astragalus full monograph & interactions

Probiotic1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Plant Enzymes, from the product label.

Innate Response Formulas

See all Innate Response Formulas products
Name
BioSan Laboratories, Inc.
Street Address
8 Bowers Road
City
Derry
State
NH
ZipCode
03038
Phone Number
800-634-6342
Web Address
www.innateresponse.com
Pharmacist Counseling Corner

Plant Enzymes by Innate Response Formulas: Common Questions

Does Plant Enzymes by Innate Response Formulas interact with any medications?
Yes. Based on its ingredients, Plant Enzymes has a known interaction with 2,260 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Plant Enzymes contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take this if I'm pregnant?
There isn't enough reliable data on several ingredients — astragalus, marshmallow, and protease should be avoided during pregnancy. Ginger is likely safe in pregnancy but check with your doctor first and keep amounts moderate. Lactase is likely safe. Talk with your doctor before taking this product during pregnancy, since the combination and your individual health matter.
Can I take this while breastfeeding?
Data are limited. Ginger is likely safe while breastfeeding, and Lactobacillus acidophilus is probably low-risk, but astragalus, marshmallow, lipase, and protease have little safety information during breastfeeding. Ask your doctor or pharmacist before using this product while breastfeeding.
Does lactase in this product really help with lactose intolerance?
Yes — lactase is effective for lactose intolerance. It works by breaking down the milk sugar lactose in your digestive system. How well it works depends on the amount present and your individual needs.
Will ginger in this product help with nausea?
Possibly. Ginger is possibly effective for pregnancy-related nausea and appears to have some benefit, though the evidence is not definitive. It's less likely to help with chemotherapy-related nausea. Check with your doctor about using it for nausea, especially during pregnancy.
Can I take this with antibiotics?
Not at the same time. Antibiotics can kill the live Lactobacillus acidophilus organisms in this product, making the probiotic less effective. Separate your antibiotic and this product by a few hours, and ask your pharmacist for the best timing.
What side effects might I experience?
Mild digestive upset is most common — heartburn, burping, diarrhea, or abdominal discomfort, especially from ginger at higher doses. Lactobacillus acidophilus may rarely cause bloating or flatulence. Allergic reactions to enzymes are rare but possible. Stop and contact your healthcare provider if you develop severe symptoms.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Plant Enzymes label
Go deeper

The Full Monographs Behind Plant Enzymes’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Lipase

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...

Read the full Lipase monograph → Herb & supplement monograph

Lactase

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...

Read the full Lactase monograph → Herb & supplement monograph

Proteolytic Enzymes (proteases)

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...

Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monograph

Ginger

Interacts with 1,007 drugs

Ginger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nausea and vomiting, including from motion sickness, pr...

Read the full Ginger monograph → Herb & supplement monograph

Astragalus

Interacts with 208 drugs

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...

Read the full Astragalus monograph → Herb & supplement monograph

Marshmallow

Interacts with 2,040 drugs

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...

Read the full Marshmallow monograph →
Sources

Sources & How We Checked

Plant Enzymes's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 102 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Ginger 64 references
  1. Fischer-Rasmussen W, Kjaer SK, Dahl C, Asping U. Ginger treatment of hyperemesis gravidarum. Eur J Obstet Gynecol Reprod Biol 1991;38:19-24. PubMed
  2. Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev 2000;(2):CD000145. PubMed
  3. Vutyavanich T, Kraisarin T, Ruangsri R. Ginger for nausea and vomiting in pregnancy: randomized, double-masked, placebo-controlled trial. Obstet Gynecol 2001;97:577-82. DOI
  4. Backon J. Ginger in preventing nausea and vomiting of pregnancy; a caveat due to its thromboxane synthetase activity and effect on testosterone binding. Eur J Obstet Gynecol Reprod Biol 1991;42:163-4. PubMed
  5. Srivastava KC. Effect of onion and ginger consumption on platelet thromboxane production in humans. Prostaglandins Leukot Essent Fatty Acids 1989;35:183-5. PubMed
  6. Stewart JJ, Wood MJ, Wood CD, Mims ME. Effects of ginger on motion sickness susceptibility and gastric function. Pharmacology 1991;42:111-20. PubMed
  7. Smith C, Crowther C, Willson K, et al. A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstet Gynecol 2004;103:639-45. PubMed
  8. Portnoi G, Chng LA, Karimi-Tabesh L, et al. Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancy. Am J Obstet Gynecol 2003;189:1374-7.. PubMed
  9. Wigler I, Grotto I, Caspi D, Yaron M. The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis. Osteoarthritis Cartilage 2003;11:783-9. PubMed
  10. Ghayur MN, Gilani AH. Ginger lowers blood pressure through blockade of voltage-dependent calcium channels. J Cardiovasc Pharmacol 2005;45:74-80. PubMed
  11. Thomson M, Al-Qattan KK, Al-Sawan SM, et al. The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. Prostaglandins Leukot Essent Fatty Acids 2002;67:475-8. PubMed
  12. Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices. Contact Dermatitis 1996;35:157-62. PubMed
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Lactobacillus Acidophilus 15 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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