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Dietary supplement

Wahoo Ingredients & Drug Interactions

by Herbal Terra

Wahoo label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wahoo against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Wahoo is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for constipation (traditional laxative), digestive complaints, liver and gallbladder support (folk use).Based on those ingredients, 133 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are wildcrafted Wahoo (Euonymus atropurpureus) dried root bark liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wahoo by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with Wahoo by Herbal Terra — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wahoo by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: wildcrafted wahoo (Euonymus atropurpureus) dried root bark as a liquid extract. Wahoo is a plant historically used in herbal medicine, though it contains compounds that carry serious safety concerns.

The only other ingredient listed is menstruum, a carrier used in liquid extracts.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Wahoo product and its label doesn't state a use — see Wahoo's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness ratings for wahoo in our data, so the evidence for how well it works is not established here.

The evidence, ingredient by ingredient Wahoo

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wahoo is considered poisonous and the safety data advises against its use. The plant contains toxic compounds and has been historically linked to uterine stimulation.

Poisoning from wahoo seeds causes severe upset stomach — sometimes with bloody diarrhea — along with fever, shortness of breath, circulatory collapse, loss of consciousness, muscle spasms with locked jaw, and potentially coma. The safety data rates it likely unsafe in pregnancy and lactation.

Side effects, ingredient by ingredient Wahoo

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wahoo.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 133 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Do not take wahoo if you use digoxin (Lanoxin) — this combination is contraindicated. If you take water pills (diuretics), stimulant laxatives, macrolide or tetracycline antibiotics, or quinine, check with your pharmacist before considering this product, as moderate interactions are documented.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

We cannot recommend this product. Wahoo carries major interaction risk with heart medications and moderate risk with many common drugs.

More importantly, it's classified as poisonous with a serious adverse-effect profile. If you're interested in herbal support, talk with your pharmacist about safer alternatives.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wahoo, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 0606595855829
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 235207
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wahoo by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
0606595855829
IngredientAmount% DV
wildcrafted Wahoo (Euonymus atropurpureus) dried root bark liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Origin of plant material: USA.

Manufactured in the USA in an FDA registered facility

Alcohol free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Alcohol-free liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Euonymus atropurpureus

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wahoo by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wahoo label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wahoo by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Wildcrafted Wahoo (Euonymus atropurpureus) dried root bark liquid extract

Interacts with
133 drugs
970 mg per serving

Wahoo is a North American shrub historically used as a laxative and 'liver tonic,' but it is a poisonous plant with no proven benefit and a real risk...

Wildcrafted Wahoo (Euonymus atropurpureus) dried root bark liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wahoo by Herbal Terra Drug Interactions

Want to check YOUR meds against Wahoo?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
133Drugs
1 Major 132 Moderate

Ingredients driving the most interactions

wildcrafted Wahoo (Euonymus atropurpureus) dried root bark liquid extract 133

Individual Drug Interactions

The ingredients in Wahoo interact with 133 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wahoo interact with drugs. Each result below shows which ingredient is responsible. wildcrafted Wahoo (Euonymus atropurpureus) dried root bark liquid extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Wahoo with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wildcrafted Wahoo (Euonymus atropurpureus) dried root bark liquid extract6 drug types · 133 drugs

Digoxin (Lanoxin)

Contraindicated; using wahoo with digoxin increases risk of cardiac glycoside toxicity due to therapeutic duplication.

Likelihood Likely Evidence D
Diuretic Drugs

Theoretically, concomitant use of potassium-depleting diuretics with wahoo can increase the risk of cardiac glycoside toxicity due to potassium depletion. Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.

Likelihood Possible Evidence D
Macrolide Antibiotics

Theoretically, concomitant use may increase risk of cardiac glycoside toxicity.

Likelihood Possible Evidence D
Quinine

Theoretically, concomitant use of quinine and wahoo might increase risk of cardiac toxicity.

Likelihood Possible Evidence D
Stimulant Laxatives

Theoretically, use of stimulant laxatives with wahoo might have additive laxative effects, and can increase the risk of cardiac glycoside toxicity due to potassium depletion.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, concomitant use may increase risk of cardiac glycoside toxicity.

Likelihood Possible Evidence D
wildcrafted Wahoo (Euonymus atropurpureus) dried root bark liquid extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wahoo, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

Wahoo by Herbal Terra: Common Questions

Does Wahoo by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Wahoo has a known interaction with 133 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wahoo contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is wahoo safe to take?
No. Wahoo is considered poisonous and contains toxic compounds. Ingestion has caused severe poisoning with bloody diarrhea, breathing problems, heart issues, loss of consciousness, muscle spasms, and coma. The safety data advises against its use.
Can I take wahoo while pregnant or breastfeeding?
No. Wahoo is rated likely unsafe in pregnancy and lactation. The plant has been historically linked to uterine stimulation, and safety is unknown. Do not use it if you're pregnant or nursing.
What happens if I take wahoo with my heart medication?
If your heart medication is digoxin (Lanoxin), the combination is contraindicated — it can cause life-threatening heart toxicity. Even if you take a different heart drug, wahoo's interaction risk is serious enough that you must check with your pharmacist before using it.
What are the side effects of wahoo?
Wahoo poisoning causes severe upset stomach — sometimes bloody diarrhea — fever, shortness of breath, heart and circulation problems, unconsciousness, muscle spasms with locked jaw, and potentially coma. These effects can appear within hours of ingestion.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wahoo label
Go deeper

The Full Monographs Behind Wahoo’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wahoo

Interacts with 133 drugs

Wahoo is a North American shrub historically used as a laxative and 'liver tonic,' but it is a poisonous plant with no proven benefit and a real risk of serious harm. Because it contains hea...

Read the full Wahoo monograph →
Sources

Sources & How We Checked

Wahoo's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wahoo 4 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Burnham TH, ed. Drug Facts and Comparisons, Updated Monthly. Facts and Comparisons, St. Louis, MO.

See these in context on the Wahoo monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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