Cisplatin

Name: Cisplatin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

10 interactions

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Aspirin Aspirin Rectal Doxorubicin Furosemide Injection Melphalan Melphalan Injection

6 Major 4 Moderate

All (10) Major (6) Moderate (4)

Major

Cisplatin Aspirin Acuprin® Increased aspirin exposure and an increased risk of nephrotoxicity Details Cisplatin Aspirin Rectal Aspirin Increased aspirin exposure and an increased risk of nephrotoxicity Details Cisplatin Doxorubicin Adriamycin Leukemia Details Cisplatin Furosemide Injection Disal An increased ototoxicity and an increased risk of nephrotoxicity Details Cisplatin Melphalan Alkeran Altered melphalan clearance Details Cisplatin Melphalan Injection Alkeran Altered melphalan clearance Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.