Ripretinib

Name: Ripretinib Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

5 interactions 1 explained in plain English

Also sold as: Qinlock Qinlock®

About Ripretinib

Ripretinib is used to treat gastrointestinal stromal tumors (GIST; a type of tumor that grows in the stomach, intestine [bowel], or esophagus [tube that connects the throat with the stomach]) in adults who have previously received other medications, including imatinib (Gleevec). Ripretinib is in a class of medications… Read the full Ripretinib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abametapir Letermovir Injection Nafcillin Injection

3 Major 2 Moderate

All (5) Major (3) Moderate (2)

Moderate

Ripretinib Ketoconazole Topical Extina® Foam Increased exposure of ripretinib and its active metabolite and increased risk of adverse reactions Details Ripretinib Levothyroxine Ermeza Increased risk of hypothyroidism Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.