Drug & supplement interaction

Avocado Sugar Extract + Tolnaftate

Tolnaftate brand name: Tinactin.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Avocado Sugar Extract and Tolnaftate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Avocado Sugar Extract and Tolnaftate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tolnaftate and Avocado Sugar Extract in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Avocado Sugar Extract safety at a glance

Avocado Sugar Extr... overall Not established Human safety data are very limited, so its long-term safety is not well established.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoiding it is the cautious choice.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tolnaftate and Avocado Sugar Extract? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Tolnaftate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Tolnaftate is filed under 2 classifications — antifungals, oral drugs. Avocado Sugar Extract has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Tolnaftate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Avocado Sugar Extract Does Interact With Other Medications

Avocado Sugar Extract has 86 moderate known drug interactions in our database — Tolnaftate isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Tolnaftate)
Taking anything else?

Check Another of Your Medications Against Avocado Sugar Extract

Covers the 2,830 medications we’ve checked against Avocado Sugar Extract. Pick one to open its full report.

From our Q&A

Questions About Avocado Sugar Extract or Tolnaftate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Avocado Sugar Extract or Tolnaftate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Tolnaftate

This page covers Avocado Sugar Extract only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tolnaftate page lists 20 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 12 minor.

From our pharmacist’s overview on the Tolnaftate page

“For anyone using tolnaftate (Tinactin), the antifungal in athlete's foot creams and sprays, activated charcoal is the interaction to understand before all others. It holds the only major rating among the 20 ingredients on file, since charcoal binds many medicines and can lower how much reaches the body, even drugs not given by mouth.”

Reviewed by 2 · Jul 18, 2026

Open the Tolnaftate interaction page

How much people look this up

Where Avocado Sugar Extract and Tolnaftate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Avocado Sugar Extract
Steady interest

#829 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tolnaftate
Steady interest

#1,876 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Avocado Sugar Extract reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Avocado Sugar Extract and Tolnaftate records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Avocado Sugar Extract

What is Avocado Sugar Extract?

  • Blood sugar support
  • Weight management
  • Healthy aging/longevity interest
  • Metabolic support
  • Athletic/animal supplement formulas

Avocado sugar extract is a source of D-mannoheptulose, an unusual sugar studied mainly in laboratory and animal research for its possible effects on glucose metabolism. Human evidence is very limited, so it should not be relied on to treat diabetes or any condition. Talk with your pharmacist or doctor before using it, especially if you have blood sugar concerns.

Persea americana · Lauraceae · Fruit (avocado pulp) · Capsules, powders, and standardized extracts; sometimes included in supplement blends

An interaction check asks whether these two react with each other — it does not ask whether Avocado Sugar Extract is a good idea for someone in your situation. Here is what our Avocado Sugar Extract record says about it on its own.

Avocado Sugar Extract: dosing

There is no established standardized dose for avocado sugar extract or D-mannoheptulose in humans. Products vary widely in how much extract they contain and how it is standardized.If you choose to use it, follow the directions on the product label and do not exceed them.

From our Avocado Sugar Extract monograph — the full record covers uses, side effects and every documented interaction.

Read the full Avocado Sugar Extract monograph & all interactions
Medication

About Tolnaftate

What Is Tolnaftate Used For?

Brand name: Tinactin

Tolnaftate treats common fungal skin infections — specifically athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis). It also helps relieve the itching, cracking, burning, scaling, redness, and soreness that come with these infections.

Several products also help prevent athlete's foot from coming back with regular daily use. Note that tolnaftate is not effective on the scalp or nails — though some patch products are applied around the nail and cuticle area to address skin surrounding the nail.

Most-Reported Side Effects for Tolnaftate

From FAERS, the FDA’s public side-effect reporting system (1,403 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 88 reports
Nausea 86 reports
Dyspnea 80 reports
Diarrhea 73 reports
Anxiety 69 reports
See full Tolnaftate drug information
Keep checking

Other Drugs & Avocado Sugar Extract

Browse every other medication we’ve checked against Avocado Sugar Extract — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Avocado Sugar Extract page.

No interaction 2,743 drugs checked — show the list

We also checked Avocado Sugar Extract against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Avocado Sugar Extract list.

See the full Avocado Sugar Extract interactions page
See every supplement checked against Tolnaftate, ranked by severity
Evidence & sources

Avocado Sugar Extract References

The 1 references that drive our Avocado Sugar Extract monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Shaw PE, Wilson CW 3rd, Knight RJ Jr. High-performance liquid chromatographic analysis of D-manno-heptulose, perseitol, glucose, and fructose in avocado cultivars. J Agric Food Chem 1980;28:379-62. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Avocado Sugar Extract and Tolnaftate Together: Common Questions

Is it safe to take Avocado Sugar Extract with Tolnaftate?
We do not list a known interaction between Avocado Sugar Extract and Tolnaftate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Avocado Sugar Extract and Tolnaftate combination checked?
Interactions in our licensed database are recorded against drug classes. Tolnaftate is filed under 2 classifications, and Avocado Sugar Extract has documented interactions with 1 drug class — none of Tolnaftate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Avocado Sugar Extract interact with any other medications?
Yes. Avocado Sugar Extract has 86 documented drug interactions in our database — Tolnaftate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Tolnaftate interact with any supplements?
Yes. Tolnaftate has documented interactions with 20 supplements in our database — Avocado Sugar Extract is not one of them. The Tolnaftate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Avocado Sugar Extract monograph Uses, safety profile, and every drug interaction in one place Tolnaftate drug information The full plain-English guide to this medication Tolnaftate supplement interactions Every supplement checked against Tolnaftate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Tolnaftate and Avocado Sugar Extract?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.