Drug & supplement interaction

Brussels Sprout + Goserelin

Goserelin brand name: Zoladex.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Brussels Sprout and Goserelin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Brussels Sprout and Goserelin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Goserelin and Brussels Sprout in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Brussels Sprout safety at a glance

Brussels Sprout overall Generally safe Generally safe and healthy when eaten as a normal food.
Pregnancy Generally safe Safe to eat in normal food amounts during pregnancy; concentrated supplements are not well studied.
Breastfeeding Generally safe Safe as a food while breastfeeding; concentrated extracts have not been studied.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Goserelin and Brussels Sprout? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Goserelin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Goserelin is filed under a single classification — oral drugs. Brussels Sprout has documented interactions with 5 drug classes — the most serious being acetaminophen (tylenol, others) (moderate), cytochrome p450 1a2 (cyp1a2) substrates (moderate) and glucuronidated drugs (moderate) — and none of Goserelin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Brussels Sprout Does Interact With Other Medications

Brussels Sprout has 241 moderate known drug interactions in our database — Goserelin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 241 No known interaction 2,589 (incl. Goserelin)
Taking anything else?

Check Another of Your Medications Against Brussels Sprout

Covers the 2,830 medications we’ve checked against Brussels Sprout. Pick one to open its full report.

What to actually watch for

What Brussels Sprout Itself Has Been Linked To

This is not an interaction — nothing below involves Goserelin. It is the side-effect record for Brussels Sprout on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Brussels Sprout, this list is the first place to look.

  • Bloating or gas Additional detail

    “Orally, Brussels sprout is generally well-tolerated when consumed in dietary amounts. Eating Brussels sprout or other types of fermentable carbohydrates can cause flatulence.”

    Brussels Sprout · Natural Medicines adverse-effect record, reported in flatulence.

    1 source cited
    1. 26470. Allaby RG, Peterson GW, Merriwether DA, Fu YB. Evidence of the domestication history of flax (Linum usitatissimum L.) from genetic diversity of the sad2 locus. Theor Appl Genet. 2005 Dec;112(1):58-65. PubMed

    “Orally, eating Brussels sprout or other types of fermentable carbohydrates can cause flatulence.”

    Brussels Sprout · Natural Medicines adverse-effect record, reported in flatulence.

    1 source cited
    1. 26470. Allaby RG, Peterson GW, Merriwether DA, Fu YB. Evidence of the domestication history of flax (Linum usitatissimum L.) from genetic diversity of the sad2 locus. Theor Appl Genet. 2005 Dec;112(1):58-65. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Brussels Sprout — expand a row for the licensed statement it rests on. We haven’t matched Goserelin to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Goserelin.

Overlapping uses

What Goserelin Is Prescribed For, and What Brussels Sprout Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Goserelin is a prescription medicine with approved uses on its FDA label. Brussels Sprout is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Brussels Sprout has been studied for:

  • Breast cancer studied, not established Brussels Sprout has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Brussels Sprout for breast cancer

    Some population research has found that higher intake of cruciferous vegetables, including broccoli, Brussels sprout, cabbage, cauliflower, collards, and kale, is associated with a slight increase in the risk of breast cancer in premenopausal adults, while higher intake appears to be associated with a slight but statistically insignificant decrease in the risk in postmenopausal adults.

    3 sources cited
    1. 26188. Gaudet MM, Britton JA, Kabat GC, et al. Fruits, vegetables, and micronutrients in relation to breast cancer modified by menopause and hormone receptor status. Cancer Epidemiol Biomarkers Prev 2004;13(9):1485-94. DOI
    2. 26189. Smith-Warner SA, Spiegelman D, Yaun SS, et al. Intake of fruits and vegetables and risk of breast cancer: a pooled analysis of cohort studies. JAMA 2001;285(6):769-76.
    3. 112086. Davis SJ, Arscott SA, Goltz S, Muir C, Binkley N, Tanumihardjo SA. Urinary 2- to 16a-hydroxyestrone ratio did not change with cruciferous vegetable intake in premenopausal women. Int J Vitam Nutr Res. 2023 Jun 19. doi: 10.1024/0300-9831/a000785.
  • Prostate cancer studied, not established Brussels Sprout has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Brussels Sprout for prostate cancer

    Population research has found that people who consume higher amounts of Brussels sprout and other cruciferous vegetables have a lower risk of developing prostate cancer.

    2 sources cited
    1. 25420. Cohen, J. H., Kristal, A. R., and Stanford, J. L. Fruit and vegetable intakes and prostate cancer risk. J Natl.Cancer Inst. 1-5-2000;92(1):61-68. PubMed
    2. 25421. Kolonel, L. N., Hankin, J. H., Whittemore, A. S., Wu, A. H., Gallagher, R. P., Wilkens, L. R., John, E. M., Howe, G. R., Dreon, D. M., West, D. W., and Paffenbarger, R. S., Jr. Vegetables, fruits, legumes and prostate cancer: a multiethnic case-control st

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Goserelin on your own; if you are taking Brussels Sprout for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Goserelin

This page covers Brussels Sprout only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Goserelin page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Goserelin page

“Goserelin (Zoladex) is given as a small implant under the skin, usually for prostate cancer, certain breast cancers, or endometriosis, and I would want anyone on it to read this list with real attention. All 17 flagged ingredients raise the same basic concern, changing how drugs are absorbed or retained, and the single major-rated one…”

Reviewed by 2 · Jul 18, 2026

Open the Goserelin interaction page

How much people look this up

Where Brussels Sprout and Goserelin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Brussels Sprout
Steady interest

#836 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Goserelin
Steady interest

#1,777 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Brussels Sprout reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Brussels Sprout and Goserelin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Brussels Sprout

What is Brussels Sprout?

  • General nutrition and fiber
  • Antioxidant support
  • Digestive health
  • Heart health support
  • Cancer-prevention interest

Brussels sprouts are a nutritious cruciferous vegetable rich in fiber, vitamin C, vitamin K, and plant compounds called glucosinolates. Eating them as part of a balanced diet is healthy and safe for most people, but supplement-style claims (like preventing cancer) are not well proven. If you take blood thinners or have thyroid concerns, talk with your pharmacist or doctor about your intake.

Brassica oleracea var. gemmifera · Brassicaceae · Edible sprouts (small leafy buds) · Fresh or cooked vegetable, frozen, powdered, capsule or extract supplements

An interaction check asks whether these two react with each other — it does not ask whether Brussels Sprout is a good idea for someone in your situation. Here is what our Brussels Sprout record says about it on its own.

Brussels Sprout: dosing

There is no official "dose" for Brussels sprouts because they are a food, not a drug. A normal serving as part of meals is appropriate for most people, and they can be enjoyed several times a week as part of a vegetable-rich diet.If you choose a Brussels sprout or cruciferous vegetable supplement, there is no standardized, proven dose.

From our Brussels Sprout monograph — the full record covers uses, side effects and every documented interaction.

Read the full Brussels Sprout monograph & all interactions
Medication

About Goserelin Implant

What Is Goserelin Implant Used For?

Brand name: Zoladex

  • Goserelin implant is used in combination with radiation therapy and other medications to treat localized prostate cancer and is used alone to treat the symptoms associated with advanced prostate cancer. It is also used to treat advanced breast cancer in certain women. It is also used to manage endometriosis (a condition in which the type of tissue that lines the uterus [womb] grows in other areas of the body and causes pain, heavy or irregular menstruation [periods], and other symptoms) and to help with the treatment of abnormal bleeding of the uterus. Goserelin implant is in a class of medications called gonadotropin-releasing hormone (GnRH) agonists. It works by decreasing the amount of certain hormones in the body.

Most-Reported Side Effects for Goserelin

From FAERS, the FDA’s public side-effect reporting system (13,351 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Malignant neoplasm progression 1,340 reports
Fatigue 886 reports
Metastases to bone 698 reports
Neutropenia 656 reports
Nausea 600 reports
See full Goserelin Implant drug information
Keep checking

Other Drugs & Brussels Sprout

Browse every other medication we’ve checked against Brussels Sprout — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
241Moderate
0Minor
2,588No known interaction
241 Moderate 2,588 No interaction
Moderate

241 interactions

Showing 60 of 241 moderate interactions — see all 241 on the Brussels Sprout page.

No interaction 2,588 drugs checked — show the list

We also checked Brussels Sprout against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,588 medications checked with no known interaction — see the full Brussels Sprout list.

See the full Brussels Sprout interactions page
See every supplement checked against Goserelin, ranked by severity
Evidence & sources

Brussels Sprout References

The 19 references that drive our Brussels Sprout monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pantuck EJ, Pantuck CB, Anderson KE, et al. Effect of brussels sprouts and cabbage on drug conjugation. Clin Pharmacol Ther 1984;35:161-9. PubMed
  2. Joshipura KJ, Ascherio A, Manson JE, et al. Fruit and vegetable intake in relation to risk of ischemic stroke. JAMA 1999;282:1233-39. PubMed
  3. Zhao H, Lin J, Grossman HB, et al. Dietary isothiocyanates, GSTM1, GSTT1, NAT2 polymorphisms and bladder cancer risk. Int J Cancer 2007;120:2208-13.
  4. Cohen, J. H., Kristal, A. R., and Stanford, J. L. Fruit and vegetable intakes and prostate cancer risk. J Natl.Cancer Inst. 1-5-2000;92(1):61-68. PubMed
  5. Kolonel, L. N., Hankin, J. H., Whittemore, A. S., Wu, A. H., Gallagher, R. P., Wilkens, L. R., John, E. M., Howe, G. R., Dreon, D. M., West, D. W., and Paffenbarger, R. S., Jr. Vegetables, fruits, legumes and prostate cancer: a multiethnic case-control st
  6. Kissel JT, Scott CB, Reyna SP, Crawford TO, Simard LR, Krosschell KJ, Acsadi G, Elsheik B, Schroth MK, D'Anjou G, LaSalle B, Prior TW, Sorenson S, Maczulski JA, Bromberg MB, Chan GM, Swoboda KJ; Project Cure Spinal Muscular Atrophy Investigators' Network.
  7. Ovesen L, Lyduch S, Idorn ML. The effect of a diet rich in Brussels sprouts on warfarin pharmacokinetics. Eur J Clin Pharmacol 1998;34(5):521-523. PubMed
  8. Wortelboer HM, de Kruif CA, van Iersel AAJ, et al. Effects of cooked Brussels sprouts on cytochrome P-450 profile and phase II enzymes in liver and small intestinal mucosa of the rat. Food Chem Toxicol 1992;30(1):17-27. PubMed
  9. Michaud DS, Spiegelman D, Clinton SK, et al. Fruit and vegetable intake and incidence of bladder cancer in a male prospective cohort. J Natl Cancer Inst 1999;91(7):605-13. PubMed
  10. Chang ET, Smedby KE, Zhang SM, et al. Dietary factors and risk of non-Hodgkin lymphoma in men and women. Cancer Epidemiol Biomarkers Prev 2005;14(2):512-20. PubMed
  11. Liu S, Serdula M, Janket SJ, et al. A prospective study of fruit and vegetable intake and the risk of type 2 diabetes in women. Diabetes Care 2004;27(12):2993-6. PubMed
  12. Gaudet MM, Britton JA, Kabat GC, et al. Fruits, vegetables, and micronutrients in relation to breast cancer modified by menopause and hormone receptor status. Cancer Epidemiol Biomarkers Prev 2004;13(9):1485-94. DOI
  13. Smith-Warner SA, Spiegelman D, Yaun SS, et al. Intake of fruits and vegetables and risk of breast cancer: a pooled analysis of cohort studies. JAMA 2001;285(6):769-76.
  14. Rohrmann S, Giovannucci E, Willett WC, Platz EA. Fruit and vegetable consumption, intake of micronutrients, and benign prostatic hyperplasia in US men. Am J Clin Nutr 2007;85(2):523-9. PubMed
  15. Brennan P, Hsu CC, Moullan N, et al. Effect of cruciferous vegetables on lung cancer in patients stratified by genetic status: a mendelian randomisation approach. Lancet 2005;366(9496):1558-60. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Brussels Sprout and Goserelin Together: Common Questions

Is it safe to take Brussels Sprout with Goserelin?
We do not list a known interaction between Brussels Sprout and Goserelin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Brussels Sprout and Goserelin used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Brussels Sprout in each. That is a conversation for your prescriber, especially if Goserelin is being adjusted to a target.
How was the Brussels Sprout and Goserelin combination checked?
Interactions in our licensed database are recorded against drug classes. Goserelin is filed under 1 classification, and Brussels Sprout has documented interactions with 5 drug classes — none of Goserelin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Brussels Sprout interact with any other medications?
Yes. Brussels Sprout has 241 documented drug interactions in our database — Goserelin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Goserelin interact with any supplements?
Yes. Goserelin has documented interactions with 17 supplements in our database — Brussels Sprout is not one of them. The Goserelin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Brussels Sprout monograph Uses, safety profile, and every drug interaction in one place Goserelin Implant drug information The full plain-English guide to this medication Goserelin supplement interactions Every supplement checked against Goserelin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 19 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.