Drug & supplement interaction

Cannabigerol (cbg) + Etoposide

Etoposide brand names: VePesid, VP16, Etopophos.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Cannabigerol (cbg) and Etoposide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Cannabigerol (cbg) and Etoposide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Etoposide and Cannabigerol (cbg) in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Cannabigerol (cbg) safety at a glance

Cannabigerol (cbg) overall Use caution Early reports suggest it is usually well tolerated, but high-quality human safety data are lacking.
Pregnancy Avoid Cannabis-derived products are not considered safe in pregnancy; avoid use.
Breastfeeding Avoid Cannabinoids can pass into breast milk, so avoid CBG while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Etoposide and Cannabigerol (cbg)? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Etoposide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Etoposide is filed under 7 classifications — including topoisomerase ii inhibitors, antineoplastics, organic anion-transporting polypeptide substrates (oatp). Cannabigerol (cbg) has documented interactions with 1 drug class — the most serious being antihypertensive drugs (moderate) — and none of Etoposide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Cannabigerol (cbg) Does Interact With Other Medications

Cannabigerol (cbg) has 172 moderate known drug interactions in our database — Etoposide isn’t one of them. If you take anything else, check it against the full list below.

Moderate 172 No known interaction 2,658 (incl. Etoposide)
Taking anything else?

Check Another of Your Medications Against Cannabigerol (cbg)

Covers the 2,830 medications we’ve checked against Cannabigerol (cbg). Pick one to open its full report.

What to actually watch for

What Etoposide’s Own FDA Label Lists

This is not an interaction — none of it involves Cannabigerol (cbg). These are the most notable effects listed in the ADVERSE REACTIONS section of Etoposide’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A low white blood cell count Worth acting on mentioned in 17.3% of FDA reports for Etoposide
  • Loss of vision Worth acting on
  • Trouble swallowing Worth acting on
  • A low platelet count Worth acting on mentioned in 5.6% of FDA reports for Etoposide
  • Fainting Worth acting on
  • Wheezing Worth acting on
  • A severe skin reaction Worth acting on
  • Anemia Worth acting on mentioned in 4.6% of FDA reports for Etoposide
  • Seizures Worth acting on
  • Raised blood pressure Worth acting on

Showing the 10 most notable of 36 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Etoposide. Read the label on DailyMed › Where a percentage is shown, it is the share of 74,570 voluntary FDA FAERS reports for Etoposide that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Cannabigerol (cbg)’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Cannabigerol (cbg) side to compare — that is a limit of the record, not a statement that Cannabigerol (cbg) has no side effects.

Everything else you take

See Every Supplement That Interacts With Etoposide

This page covers Cannabigerol (cbg) only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Etoposide page lists 152 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Apple (major), Grapefruit (major), St. John's Wort (major) and Sweet Orange (major).

By severity: 5 major · 107 moderate · 40 minor.

From our pharmacist’s overview on the Etoposide page

“Chemotherapy is unforgiving of level swings, and swings are exactly what most of this list can cause for etoposide (VePesid, Etopophos). Of the 152 supplements and herbs on file, 121 can change how your liver clears etoposide through the CYP3A4 enzyme, meaning too little drug and an undertreated cancer, or too much and harsher toxicity.”

Reviewed by 2 · Jul 18, 2026

Open the Etoposide interaction page

How much people look this up

Where Cannabigerol (cbg) and Etoposide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Cannabigerol (cbg)
Steady interest

#826 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Etoposide
Steady interest

#1,828 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cannabigerol (cbg) reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Cannabigerol (cbg) and Etoposide records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Cannabigerol (cbg)

What is Cannabigerol (cbg)?

  • Anxiety and stress
  • Pain and inflammation
  • Sleep support
  • Focus and mood
  • Digestive discomfort

Cannabigerol (CBG) is a minor cannabinoid from the cannabis (hemp) plant that is marketed for anxiety, pain, and inflammation, but human research is very limited and most claims rest on laboratory and animal studies. It appears to be generally well tolerated in early reports, but its long-term safety, quality, and dosing are not well established. Talk to your pharmacist or doctor before trying it, especially if you take other medicines or are pregnant or breastfeeding.

Cannabis sativa · Cannabaceae · Flowers and aerial parts (extracted cannabinoid) · Oils and tinctures, capsules, gummies, vapes, topicals

An interaction check asks whether these two react with each other — it does not ask whether Cannabigerol (cbg) is a good idea for someone in your situation. Here is what our Cannabigerol (cbg) record says about it on its own.

Cannabigerol (cbg): dosing

There is no established, standardized dose for CBG. Because human research is so limited, experts have not defined how much to take, how often, or for how long.If you and your healthcare provider decide to try it, follow the directions on the product label and consider starting with the lowest suggested amount. Do not assume that more is better.

From our Cannabigerol (cbg) monograph — the full record covers uses, side effects and every documented interaction.

Read the full Cannabigerol (cbg) monograph & all interactions
Medication

About Etoposide

What Is Etoposide Used For?

Brand names: VePesid, VP16, Etopophos

Etoposide injection (available as Avopef, Etopophos, Toposar, and Etoposide) is used to treat refractory testicular tumors — cancers that have already been treated with surgery, radiation, and other chemotherapy — always in combination with other cancer drugs. It is also used for small cell lung cancer (SCLC) as a first-line treatment, given together with other chemotherapy and, in the case of Avopef, with immunotherapy as well.

Etoposide capsules (VePesid and Etoposide capsules) are approved for small cell lung cancer as first-line treatment in combination with other chemotherapy agents. Capsule forms are not approved for testicular cancer, as the label notes that adequate data on their use in that setting are not available.

Most-Reported Side Effects for Etoposide

From FAERS, the FDA’s public side-effect reporting system (74,570 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Febrile neutropenia 7,773 reports
Neutropenia 5,108 reports
Disease progression 4,642 reports
Thrombocytopenia 4,169 reports
Fever 3,494 reports
See full Etoposide drug information
Keep checking

Other Drugs & Cannabigerol (cbg)

Browse every other medication we’ve checked against Cannabigerol (cbg) — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
172Moderate
0Minor
2,657No known interaction
172 Moderate 2,657 No interaction
Moderate

172 interactions

Showing 60 of 172 moderate interactions — see all 172 on the Cannabigerol (cbg) page.

No interaction 2,657 drugs checked — show the list

We also checked Cannabigerol (cbg) against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,657 medications checked with no known interaction — see the full Cannabigerol (cbg) list.

See the full Cannabigerol (cbg) interactions page
See every supplement checked against Etoposide, ranked by severity
Evidence & sources

Cannabigerol (cbg) References

The 1 references that drive our Cannabigerol (cbg) monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Vernail VL, Bingaman SS, Silberman Y, Raup-Konsavage WM, Vrana KE, Arnold AC. Acute cannabigerol administration lowers blood pressure in mice. Front Physiol 2022;13:871962. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Cannabigerol (cbg) and Etoposide Together: Common Questions

Is it safe to take Cannabigerol (cbg) with Etoposide?
We do not list a known interaction between Cannabigerol (cbg) and Etoposide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Cannabigerol (cbg) and Etoposide combination checked?
Interactions in our licensed database are recorded against drug classes. Etoposide is filed under 7 classifications, and Cannabigerol (cbg) has documented interactions with 1 drug class — none of Etoposide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Cannabigerol (cbg) interact with any other medications?
Yes. Cannabigerol (cbg) has 172 documented drug interactions in our database — Etoposide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Etoposide interact with any supplements?
Yes. Etoposide has documented interactions with 152 supplements in our database — Cannabigerol (cbg) is not one of them. The Etoposide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Cannabigerol (cbg) monograph Uses, safety profile, and every drug interaction in one place Etoposide drug information The full plain-English guide to this medication Etoposide supplement interactions Every supplement checked against Etoposide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Etoposide and Cannabigerol (cbg)?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.