Drug & supplement interaction

Damiana + Diethylpropion

Diethylpropion brand names: Radtue, Tenuate, Durad, Tenuate Dosepan.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Damiana and Diethylpropion in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Damiana and Diethylpropion

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Diethylpropion and Damiana in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Damiana safety at a glance

Damiana overall Use caution Likely fine in food/tea amounts for most adults, but human safety data are limited.

Pregnancy Avoid Not enough safety data; avoid during pregnancy.

Breastfeeding Avoid Not enough safety data; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Diethylpropion and Damiana? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Diethylpropion

Interactions in our licensed database are recorded against drug classes, not just single drug names. Diethylpropion is filed under 2 classifications — stimulant drugs, oral drugs. Damiana has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Diethylpropion’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Damiana Does Interact With Other Medications

Damiana has 86 moderate known drug interactions in our database — Diethylpropion isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Diethylpropion)

Taking anything else?

Check Another of Your Medications Against Damiana

Covers the 2,830 medications we’ve checked against Damiana. Pick one to open its full report.

What to actually watch for

What Damiana Itself Has Been Linked To

This is not an interaction — nothing below involves Diethylpropion. It is the side-effect record for Damiana on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Damiana, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

Seizures Worth acting on Additional detail
“Orally, 200 grams of damiana extract has caused tetanus-like convulsions and paroxysms resulting in symptoms similar to rabies or strychnine poisoning (4).”

Damiana · Natural Medicines adverse-effect record, reported in poisoning.
1 source cited

4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

Everything above comes from the Natural Medicines adverse-effect record for Damiana — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Diethylpropion’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Diethylpropion column appears here.

Overlapping uses

What Diethylpropion Is Prescribed For, and What Damiana Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Diethylpropion is a prescription medicine with approved uses on its FDA label. Damiana is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Diethylpropion is prescribed for: Diethylpropion is used to help manage exogenous obesity (excess body weight from outside factors like diet) in adults with a body mass index (BMI) of 30 or higher who haven't lost enough weight through diet and exercise alone. It is meant to be used for only a few weeks as part of a calorie-restricted diet plan. All available tablet products — both the immediate-release tablets and the extended-release tablets — are approved for this purpose. Each is approved for use as a single medication only; combining diethylpropion with any other weight-loss drug is not allowed.

Damiana has been studied for:

Obesity studied, not established Damiana has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

Damiana for obesity

Oral damiana has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Diethylpropion on your own; if you are taking Damiana for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Diethylpropion

This page covers Damiana only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Diethylpropion page lists 61 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Ephedra (major), Peyote (major), Rauvolfia Vomitoria (major) and Sida Cordifolia (major).

By severity: 5 major · 43 moderate · 13 minor.

From our pharmacist’s overview on the Diethylpropion page

“Diethylpropion (Tenuate) is an appetite suppressant that works by revving up the nervous system, and that mechanism is why its interaction list calls for real vigilance. Of the 61 supplements and herbs on file, 44 add their own stimulant push, raising the risk of high blood pressure, a pounding heart, and sleeplessness.”

Reviewed by 2 · Jul 18, 2026

Open the Diethylpropion interaction page

One more smart check

Taking Damiana as Part of a Dietary Supplement Product? Check It for Interactions

We hold 881 real supplement products containing Damiana, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Damiana. Even though Damiana itself has no known interaction with Diethylpropion, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Damiana and Diethylpropion Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Damiana

Top 25%

#205 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Diethylpropion

Steady interest

#2,488 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Damiana reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Damiana and Diethylpropion records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Damiana

What is Damiana?

Low libido / aphrodisiac
Anxiety and stress
Mood and mild low energy
Digestive upset
Headache and general tonic

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small amounts found in teas, but quality studies are lacking, so talk with your pharmacist or doctor before using it—especially if you are pregnant, breastfeeding, or have a health condition.

Turnera diffusa · Passifloraceae · Leaves (and sometimes stems) · Tea, capsules, tinctures, liquid extracts, dried leaf

An interaction check asks whether these two react with each other — it does not ask whether Damiana is a good idea for someone in your situation. Here is what our Damiana record says about it on its own.

Damiana: dosing

There is no well-established standard dose for damiana. The amount people use varies widely depending on the form—tea, capsule, or tincture.The safest approach is to follow the directions on the product label and not exceed the recommended amount. Because strength differs from product to product, a pharmacist can help you decide whether a particular product and dose make sense for you.If you try damiana, start low, watch how you feel, and stop if you notice side effects.

From our Damiana monograph — the full record covers uses, side effects and every documented interaction.

Read the full Damiana monograph & all interactions

Medication

About Diethylpropion

What Is Diethylpropion Used For?

Brand names: Radtue, Tenuate, Durad, Tenuate Dosepan

Diethylpropion is used to help manage exogenous obesity (excess body weight from outside factors like diet) in adults with a body mass index (BMI) of 30 or higher who haven't lost enough weight through diet and exercise alone. It is meant to be used for only a few weeks as part of a calorie-restricted diet plan.

All available tablet products — both the immediate-release tablets and the extended-release tablets — are approved for this purpose. Each is approved for use as a single medication only; combining diethylpropion with any other weight-loss drug is not allowed.

See full Diethylpropion drug information

Keep checking

Other Drugs & Damiana

Browse every other medication we’ve checked against Damiana — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

86Moderate

0Minor

2,743No known interaction

86 Moderate 2,743 No interaction

Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Damiana page.

No interaction 2,743 drugs checked — show the list

We also checked Damiana against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Damiana list.

See the full Damiana interactions page

See every supplement checked against Diethylpropion, ranked by severity

Evidence & sources

Damiana References

The 2 references that drive our Damiana monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Damiana and Diethylpropion Together: Common Questions

Is it safe to take Damiana with Diethylpropion?

We do not list a known interaction between Damiana and Diethylpropion. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Are Damiana and Diethylpropion used for the same thing?

They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Damiana in each. That is a conversation for your prescriber, especially if Diethylpropion is being adjusted to a target.

How was the Damiana and Diethylpropion combination checked?

Interactions in our licensed database are recorded against drug classes. Diethylpropion is filed under 2 classifications, and Damiana has documented interactions with 1 drug class — none of Diethylpropion's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Damiana interact with any other medications?

Yes. Damiana has 86 documented drug interactions in our database — Diethylpropion is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Diethylpropion interact with any supplements?

Yes. Diethylpropion has documented interactions with 61 supplements in our database — Damiana is not one of them. The Diethylpropion interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Damiana monograph Uses, safety profile, and every drug interaction in one place Diethylpropion drug information The full plain-English guide to this medication Diethylpropion supplement interactions Every supplement checked against Diethylpropion, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Diethylpropion and Damiana?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.