Drug & supplement interaction

Green Tea + Mitomycin

Mitomycin brand names: Mutamycin, Mitosol, Jelmyto.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Green Tea and Mitomycin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Green Tea and Mitomycin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mitomycin and Green Tea in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Green Tea safety at a glance

Green Tea overall Use caution Drinking green tea is generally safe, but concentrated extracts in high doses have been linked to rare liver injury.
Pregnancy Possibly Safe When used orally in moderate amounts. Due to the caffeine content of green tea, pregnant patients should closely monitor their intake to ensure moderate consump... Read the full pregnancy detail
Breastfeeding Possibly Safe When used orally in moderate amounts. Due to the caffeine content of green tea, nursing parents should closely monitor caffeine intake. Breast milk concentratio... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mitomycin and Green Tea? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Mitomycin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Mitomycin is filed under 3 classifications — antitumor antibiotics, topical drugs, oral drugs. Green Tea has documented interactions with 58 drug classes — the most serious being atorvastatin (lipitor) (major), ephedrine (major) and nadolol (corgard) (major) — and none of Mitomycin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Green Tea Does Interact With Other Medications

Green Tea has 13 major, 905 moderate, 375 minor known drug interactions in our database — Mitomycin isn’t one of them. If you take anything else, check it against the full list below.

Major 13 Moderate 905 Minor 375 No known interaction 1,537 (incl. Mitomycin)
Taking anything else?

Check Another of Your Medications Against Green Tea

Covers the 2,830 medications we’ve checked against Green Tea. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Green Tea and Mitomycin May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 4 of them are worth acting on rather than waiting out — marked below.

  • A stroke or mini-stroke Worth acting on Additional detail

    Green Tea

    “Acute or short-term oral administration of green tea may cause hypertension. The risk may be greater for green tea products containing more than 200 mg epigallocatechin gallate (EGCG). However, consumption of brewed green tea does not seem to increase blood pressure or pulse, even in mildly hypertensive patients.”

    Green Tea · Natural Medicines adverse-effect record, reported in arrhythmia.

    6 sources cited
    1. 53719. Laurie, S. A., Miller, V. A., Grant, S. C., Kris, M. G., and Ng, K. K. Phase I study of green tea extract in patients with advanced lung cancer. Cancer Chemother.Pharmacol. 2005;55(1):33-38. PubMed
    2. 54014. Miller, R. J., Jackson, K. G., Dadd, T., Mayes, A. E., Brown, A. L., and Minihane, A. M. The impact of the catechol-O-methyltransferase genotype on the acute responsiveness of vascular reactivity to a green tea extract. Br.J.Nutr. 2011;105(8):1138-1144.
    3. 54065. Miller, R. J., Jackson, K. G., Dadd, T., Mayes, A. E., Brown, A. L., Lovegrove, J. A., and Minihane, A. M. The impact of the catechol-O-methyltransferase genotype on vascular function and blood pressure after acute green tea ingestion. Mol.Nutr.Food Res.
    4. 54076. Jurgens, T. M., Whelan, A. M., Killian, L., Doucette, S., Kirk, S., and Foy, E. Green tea for weight loss and weight maintenance in overweight or obese adults. Cochrane.Database.Syst.Rev. 2012;12:CD008650. PubMed
    5. 102716. Filippini T, Malavolti M, Borrelli F, et al. Green tea (Camellia sinensis) for the prevention of cancer. Cochrane Database Syst Rev. 2020;3(3):CD005004. PubMed
    6. 90161. Onakpoya I, Spencer E, Heneghan C, Thompson M. The effect of green tea on blood pressure and lipid profile: a systematic review and meta-analysis of randomized clinical trials. Nutr Metab Cardiovasc Dis. 2014 Aug;24:823-36. PubMed

    Mitomycin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mitomycin. Read the label on DailyMed ›

  • Raised blood pressure Worth acting on Additional detail

    Green Tea

    “Orally, green tea can cause central nervous system stimulation and adverse effects such as headache, anxiety, dizziness, insomnia, fatigue, agitation, tremors, restlessness, and confusion. These effects are more common with higher doses of green tea or green tea extract, equivalent to 5-6 liters of tea per day.”

    Green Tea · Natural Medicines adverse-effect record, reported in anxiety.

    6 sources cited
    1. 8117. Pisters KM, Newman RA, Coldman B, et al. Phase I trial of oral green tea extract in adult patients with solid tumors. J Clin Oncol 2001;19:1830-8. PubMed
    2. 11366. Jatoi A, Ellison N, Burch PA, et al. A phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma. Cancer 2003;97:1442-6.. PubMed
    3. 53719. Laurie, S. A., Miller, V. A., Grant, S. C., Kris, M. G., and Ng, K. K. Phase I study of green tea extract in patients with advanced lung cancer. Cancer Chemother.Pharmacol. 2005;55(1):33-38. PubMed
    4. 90139. Crew KD, Brown P, Greenlee H, Bevers TB, Arun B, Hudis C, McArthur HL, Chang J, Rimawi M, Vornik L, Cornelison TL, Wang A, Hibshoosh H, Ahmed A, Terry MB, Santella RM, Lippman SM, Hershman DL. Phase IB randomized, double-blinded, placebo-controlled, dose
    5. 102716. Filippini T, Malavolti M, Borrelli F, et al. Green tea (Camellia sinensis) for the prevention of cancer. Cochrane Database Syst Rev. 2020;3(3):CD005004. PubMed
    6. 36398. Chow, H. H., Cai, Y., Hakim, I. A., Crowell, J. A., Shahi, F., Brooks, C. A., Dorr, R. T., Hara, Y., and Alberts, D. S. Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E i

    Mitomycin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mitomycin. Read the label on DailyMed ›

  • Bleeding or bruising Worth acting on Additional detail

    Green Tea

    “Orally, green tea is generally well tolerated when consumed as a beverage in moderate amounts. Green tea extract also seems to be well tolerated when used for up to 12 months.

    Most Common Adverse Effects:

    Orally: Bloating, constipation, diarrhea, dyspepsia, flatulence, and nausea.

    Serious Adverse Effects (Rare):

    Orally: Hepatotoxicity, hypokalemia, and thrombotic thrombocytopenic purpura have been reported rarely.”

    Green Tea · Natural Medicines adverse-effect record, reported in constipation.

    Mitomycin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mitomycin. Read the label on DailyMed ›

  • An allergic reaction Worth acting on Additional detail

    Green Tea

    “There is concern that some green tea products, especially green tea extracts, can cause hepatotoxicity in some patients. In 2017, the regulatory agency Health Canada re-issued a warning to consumers about this concern. The updated warning advises patients taking green tea extracts, especially those with liver disease, to watch for signs of liver toxicity.”

    Green Tea · Natural Medicines adverse-effect record, reported in cholestasis.

    6 sources cited
    1. 94897. Green Tea Extract-Containing Natural Health Products - Rare Risk of Serious Liver Injury. Recalls & alerts. November 15, 2017. http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2017/65100a-eng.php. Accessed November 10, 2017.
    2. 102722. Oketch-Rabah HA, Roe AL, Rider CV, et al. United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts. Toxicol Rep. 2020;7:386-402. PubMed
    3. 14136. Bonkovsky HL. Hepatotoxicity associated with supplements containing Chinese green tea (Camellia sinensis). Ann Intern Med 2006;144:68-71.
    4. 15026. Jimenez-Saenz M, Martinez-Sanchez, MDC. Acute hepatitis associated with the use of green tea infusions. J Hepatol 2006;44:616-9. PubMed
    5. 53740. Javaid, A. and Bonkovsky, H. L. Hepatotoxicity due to extracts of Chinese green tea (Camellia sinensis): a growing concern. J Hepatol 2006;45(2):334-335. PubMed
    6. 53746. Molinari, M., Watt, K. D., Kruszyna, T., Nelson, R., Walsh, M., Huang, W. Y., Nashan, B., and Peltekian, K. Acute liver failure induced by green tea extracts: case report and review of the literature. Liver Transpl. 2006;12(12):1892-1895. PubMed

    “A case of granulomatous alveolitis with lymph follicles has been reported for a 67-year-old female who used green tea infusions to wash her nasal cavities for 15 years. Her symptoms disappeared 2 months after stopping this practice and following an undetermined course of corticosteroids. In a case report, hypersensitivity pneumonitis was associated with inhalation of catechin-rich green tea extracts.”

    Green Tea · Natural Medicines adverse-effect record, reported in dental caries.

    3 sources cited
    1. 54088. Sakamoto, O., Saita, N., Yamasaki, H., Tamanoi, M., and Ando, M. Pulmonary granulomatosis caused by aspirated green tea. Chest 1994;106(1):308-309. PubMed
    2. 54025. Otera, H., Tada, K., Sakurai, T., Hashimoto, K., and Ikeda, A. Hypersensitivity pneumonitis associated with inhalation of catechin-rich green tea extracts. Respiration 2011;82(4):388-392. PubMed
    3. 11365. Shirai T, Hayakawa H, Akiyama J, et al. Food allergy to green tea. J Allergy Clin Immunol 2003;112:805-6. PubMed

    Mitomycin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mitomycin. Read the label on DailyMed ›

  • Reduced appetite Additional detail

    Green Tea

    “Orally, green tea beverage or supplements can cause nausea, vomiting, abdominal bloating and pain, constipation, dyspepsia, reflux, morning anorexia, increased thirst, flatulence, and diarrhea. These effects are more common with higher doses of green tea or green tea extract, equivalent to 5-6 liters of tea per day.”

    Green Tea · Natural Medicines adverse-effect record, reported in anorexia.

    6 sources cited
    1. 8117. Pisters KM, Newman RA, Coldman B, et al. Phase I trial of oral green tea extract in adult patients with solid tumors. J Clin Oncol 2001;19:1830-8. PubMed
    2. 11366. Jatoi A, Ellison N, Burch PA, et al. A phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma. Cancer 2003;97:1442-6.. PubMed
    3. 36398. Chow, H. H., Cai, Y., Hakim, I. A., Crowell, J. A., Shahi, F., Brooks, C. A., Dorr, R. T., Hara, Y., and Alberts, D. S. Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E i
    4. 53719. Laurie, S. A., Miller, V. A., Grant, S. C., Kris, M. G., and Ng, K. K. Phase I study of green tea extract in patients with advanced lung cancer. Cancer Chemother.Pharmacol. 2005;55(1):33-38. PubMed
    5. 53867. Kalus, U., Kiesewetter, H., and Radtke, H. Effect of CYSTUS052 and green tea on subjective symptoms in patients with infection of the upper respiratory tract. Phytother.Res. 2010;24(1):96-100.
    6. 53936. Tsao, A. S., Liu, D., Martin, J., Tang, X. M., Lee, J. J., El-Naggar, A. K., Wistuba, I., Culotta, K. S., Mao, L., Gillenwater, A., Sagesaka, Y. M., Hong, W. K., and Papadimitrakopoulou, V. Phase II randomized, placebo-controlled trial of green tea extra

    Mitomycin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mitomycin. Read the label on DailyMed ›

  • Itching / A skin rash Additional detail

    Green Tea

    “Orally, green tea may cause skin rashes or skin irritation. Topically, green tea may cause local skin reactions or skin irritation, erythema, burning, itching, edema, and erosion. A green tea extract ointment applied to the cervix can cause cervical and vaginal inflammation, vaginal irritation, and vulval burning.”

    Green Tea · Natural Medicines adverse-effect record, reported in erythema.

    6 sources cited
    1. 53731. Chiu, A. E., Chan, J. L., Kern, D. G., Kohler, S., Rehmus, W. E., and Kimball, A. B. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin. Dermatol Surg. 2005;31(7 Pt 2):855-860. PubMed
    2. 54038. Zheng XX, Xu YL, Li SH, et al. Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials. Am.J.Clin.Nutr. 2011;94:601-610. PubMed
    3. 90161. Onakpoya I, Spencer E, Heneghan C, Thompson M. The effect of green tea on blood pressure and lipid profile: a systematic review and meta-analysis of randomized clinical trials. Nutr Metab Cardiovasc Dis. 2014 Aug;24:823-36. PubMed
    4. 90187. Zheng XX, Xu YL, Li SH, Hui R, Wu YJ, Huang XH. Effects of green tea catechins with or without caffeine on glycemic control in adults: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2013 Apr;97(4):750-62. PubMed
    5. 102716. Filippini T, Malavolti M, Borrelli F, et al. Green tea (Camellia sinensis) for the prevention of cancer. Cochrane Database Syst Rev. 2020;3(3):CD005004. PubMed
    6. 54018. Tzellos, T. G., Sardeli, C., Lallas, A., Papazisis, G., Chourdakis, M., and Kouvelas, D. Efficacy, safety and tolerability of green tea catechins in the treatment of external anogenital warts: a systematic review and meta-analysis. J.Eur.Acad.Dermatol.Ve PubMed

    Mitomycin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mitomycin. Read the label on DailyMed ›

  • Stomach pain Additional detail

    Green Tea

    Recorded for Green Tea in the same Natural Medicines adverse-effect record shown under An allergic reaction above.

    Mitomycin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mitomycin. Read the label on DailyMed ›

  • Tiredness Additional detail

    Green Tea

    “Green tea contains a significant amount of caffeine. Chronic use, especially in large amounts, can produce tolerance, habituation, and psychological dependence. The existence or clinical importance of caffeine withdrawal is controversial. Some researchers think that if it exists, it appears to be of little clinical significance. Other researchers suggest symptoms such as headache; tiredness and fatigue;”

    Green Tea · Natural Medicines adverse-effect record, reported in anxiety.

    4 sources cited
    1. 11832. Institute of Medicine. Caffeine for the Sustainment of Mental Task Performance: Formulations for Military Operations. Washington, DC: National Academy Press, 2001. Available at: http://books.nap.edu/books/0309082587/html/index.html. DOI
    2. 11839. Dews PB, O'Brien CP, Bergman J. Caffeine: behavioral effects of withdrawal and related issues. Food Chem Toxicol 2002;40:1257-61. PubMed
    3. 13738. Juliano LM, Griffiths RR. A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features. Psychopharmacology (Berl) 2004;176:1-29. PubMed
    4. 2723. Dews PB, Curtis GL, Hanford KJ, O'Brien CP. The frequency of caffeine withdrawal in a population-based survey and in a controlled, blinded pilot experiment. J Clin Pharmacol 1999;39:1221-32. PubMed

    Mitomycin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mitomycin. Read the label on DailyMed ›

  • Vomiting Additional detail

    Green Tea

    Recorded for Green Tea in the same Natural Medicines adverse-effect record shown under Reduced appetite above.

    Mitomycin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mitomycin. Read the label on DailyMed ›

Showing the 10 most notable of 11 shared effects — ranked by how unusual each one is, not just whether both lists mention it.

Reported for Green Tea but not commonly for Mitomycin: yellowing of the skin or eyes, trouble concentrating, dependence or withdrawal symptoms and liver problems.

Effects for Mitomycin come from the ADVERSE REACTIONS section of its FDA label; effects for Green Tea come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Green Tea in Pregnancy & Breastfeeding

Pregnancy Possibly Safe

When used orally in moderate amounts. Due to the caffeine content of green tea, pregnant patients should closely monitor their intake to ensure moderate consumption. Fetal blood concentrations of caffeine approximate maternal concentrations. The use of caffeine during pregnancy is controversial; however, moderate consumption has not been associated with clinically important adverse fetal effects. In some studies consuming amounts over 200 mg daily is associated with a significantly increased risk of miscarriage. This increased risk may be most likely to occur in those with genotypes that confer a slow rate of caffeine metabolism. According to a review by Health Canada, and a subsequent large meta-analysis conducted in the US, most healthy pregnant patients can safely consume doses up to 300 mg daily without an increased risk of spontaneous abortion, stillbirth, preterm birth, fetal growth retardation, or congenital malformations. Advise keeping caffeine consumption below 300 mg daily. This is similar to the amount of caffeine in about 6 cups of green tea. Keep in mind that only the amount of ADDED caffeine must be stated on product labels. The amount of caffeine found in ingredients such as green tea, which naturally contains caffeine, does not need to be provided. This can make it difficult to determine the total amount of caffeine in a given product. Based on animal models, green tea extract catechins are also transferred to the fetus, but in amounts 50-100 times less than maternal concentrations. The potential impact of these catechins on the human fetus is not known, but animal models suggest that the catechins are not teratogenic.

Pregnancy Possibly Unsafe

When used orally in amounts providing more than 300 mg caffeine daily. Caffeine from green tea crosses the placenta, producing fetal blood concentrations similar to maternal levels. Consumption of caffeine in amounts over 300 mg daily is associated with a significantly increased risk of miscarriage in some studies. Advise keeping caffeine consumption from all sources below 300 mg daily. This is similar to the amount of caffeine in about 6 cups of green tea. High maternal doses of caffeine throughout pregnancy have also resulted in symptoms of caffeine withdrawal in newborn infants. High doses of caffeine have also been associated with spontaneous abortion, premature delivery, and low birth weight. However, some research has also found that intrauterine exposure to even modest amounts of caffeine, based on maternal blood levels during the first trimester, is associated with a shorter stature in children ages 4-8 years. Keep in mind that only the amount of ADDED caffeine must be stated on product labels. The amount of caffeine found in ingredients such as green tea, which naturally contains caffeine, does not need to be provided. This can make it difficult to determine the total amount of caffeine in a given product. There is also concern that consuming large amounts of green tea might have antifolate activity and potentially increase the risk of folic acid deficiency-related birth defects. Catechins in green tea inhibit the enzyme dihydrofolate reductase in vitro. This enzyme is responsible for converting folic acid to its active form. Preliminary evidence suggests that increasing maternal green tea consumption is associated with increased risk of spina bifida. Also, evidence from epidemiological research suggests that serum folate levels in pregnant patients with high green tea intake (57.3 mL per 1000 kcal) are decreased compared to participants who consume moderate or low amounts of green tea. More evidence is needed to determine the safety of using green tea during pregnancy. For now, advise pregnant patients to avoid consuming large quantities of green tea.

Lactation Possibly Safe

When used orally in moderate amounts. Due to the caffeine content of green tea, nursing parents should closely monitor caffeine intake. Breast milk concentrations of caffeine are thought to be approximately 50% of maternal serum concentrations.

Lactation Possibly Unsafe

When used orally in large amounts. Consumption of green tea might cause irritability and increased bowel activity in nursing infants. There is insufficient reliable information available about the safety of green tea extracts when applied topically during breast-feeding.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Green Tea or Mitomycin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Green Tea or Mitomycin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Mitomycin

This page covers Green Tea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mitomycin page lists 26 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Acerola (moderate), Alpha-lipoic Acid (moderate), Coffee Charcoal (moderate) and Dimethylsulfoxide (dmso) (moderate).

By severity: 1 major · 15 moderate · 10 minor.

From our pharmacist’s overview on the Mitomycin page

“Activated charcoal is the entry to know first with mitomycin (Mutamycin, Mitosol, Jelmyto), a chemotherapy drug, because charcoal binds medications and can cut the amount the body receives, and it carries this list's only major rating. A weakened dose of a cancer treatment is a real loss, so I would treat these 26 interactions with gen…”

Reviewed by 2 · Jul 18, 2026

Open the Mitomycin interaction page

One more smart check

Taking Green Tea as Part of a Dietary Supplement Product? Check It for Interactions

We hold 9,084 real supplement products containing Green Tea, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Green Tea. Even though Green Tea itself has no known interaction with Mitomycin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Green Tea and Mitomycin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Green Tea
Top 5%

#26 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mitomycin
Top half

#961 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Green Tea reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Green Tea and Mitomycin records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Green Tea

What is Green Tea?

Green Tea
  • Antioxidant support
  • Weight loss
  • Heart health
  • Mental alertness
  • Cancer risk reduction

Green tea is a popular beverage rich in antioxidants called catechins, and drinking it in normal amounts is considered safe for most people. Concentrated green tea extracts are a different story—they may help modestly with weight or heart health for some, but high doses have been linked to rare liver problems. Talk to your pharmacist or doctor before taking green tea supplements, especially if you have liver concerns or are pregnant.

Camellia sinensis · Theaceae · Leaves and leaf buds · Brewed tea, capsules, tablets, standardized extracts, powders (matcha), and topical ointments

An interaction check asks whether these two react with each other — it does not ask whether Green Tea is a good idea for someone in your situation. Here is what our Green Tea record says about it on its own.

Green Tea: dosing

There is no single official dose for green tea. As a beverage, many people drink a few cups per day without problems. For supplements, the right amount depends on the product and how concentrated it is.Because extracts vary widely in strength, it is best to follow the directions on the product label and not exceed the recommended dose. They can help you decide if it is appropriate and what amount is reasonable.

From our Green Tea monograph — the full record covers uses, side effects and every documented interaction.

Read the full Green Tea monograph & all interactions
Medication

About Mitomycin

What Is Mitomycin Used For?

Brand names: Mutamycin, Mitosol, Jelmyto

Mitomycin (and its brand Mutamycin) is used intravenously in combination with other chemotherapy drugs to treat disseminated adenocarcinoma (a type of cancer that has spread) of the stomach or pancreas, when other treatments have not worked. It is not intended to replace surgery or radiation therapy.

Mitomycin is also the active ingredient in other products for different uses: Jelmyto treats low-grade upper tract urothelial cancer (cancer of the upper urinary tract); Zusduri treats recurrent low-grade intermediate-risk non-muscle invasive bladder cancer; and Mitosol is used as a surgical aid during certain glaucoma eye surgery. These are separate products with distinct indications and are not interchangeable with the intravenous injection form.

See full Mitomycin drug information
Keep checking

Other Drugs & Green Tea

Browse every other medication we’ve checked against Green Tea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

13Major
905Moderate
375Minor
1,536No known interaction
13 Major 905 Moderate 375 Minor 1,536 No interaction
Major

13 interactions

Moderate

905 interactions

Showing 60 of 905 moderate interactions — see all 905 on the Green Tea page.

Minor

375 interactions

Showing 60 of 375 minor interactions — see all 375 on the Green Tea page.

No interaction 1,536 drugs checked — show the list

We also checked Green Tea against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 1,536 medications checked with no known interaction — see the full Green Tea list.

See the full Green Tea interactions page
See every supplement checked against Mitomycin, ranked by severity
Evidence & sources

Green Tea References

The 219 references that drive our Green Tea monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Harder S, Fuhr U, Staib AH, Wolff T. Ciprofloxacin-caffeine: a drug interaction established using in vivo and in vitro investigations. Am J Med 1989;87:89S-91S. PubMed
  3. Carbo M, Segura J, De la Torre R, et al. Effect of quinolones on caffeine disposition. Clin Pharmacol Ther 1989;45:234-40. PubMed
  4. Healy DP, Polk RE, Kanawati L, et al. Interaction between oral ciprofloxacin and caffeine in normal volunteers. Antimicrob Agents Chemother 1989;33:474-8. PubMed
  5. Mester R, Toren P, Mizrachi I, et al. Caffeine withdrawal increases lithium blood levels. Biol Psychiatry 1995;37:348-50. PubMed
  6. Jefferson JW. Lithium tremor and caffeine intake: two cases of drinking less and shaking more. J Clin Psychiatry 1988;49:72-3.
  7. Mitscher LA, Mitscher LA, Jung M, Shankel D, et al. Chemoprotection: a review of the potential therapeutic antioxidant properties of green tea (Camellia sinensis) and certain of its constituents. Med Res Rev 1997;17:327-65.
  8. Joeres R, Klinker H, Heusler H, et al. Influence of mexiletine on caffeine elimination. Pharmacol Ther 1987;33:163-9. PubMed
  9. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
  10. Wakabayashi K, Kono S, Shinchi K, et al. Habitual coffee consumption and blood pressure: A study of self-defense officials in Japan. Eur J Epidemiol 1998;14:669-73. PubMed
  11. Hodgson JM, Puddey IB, Burke V, et al. Effects on blood pressure of drinking green and black tea. J Hypertens 1999;17:457-63. PubMed
  12. Booth SL, Madabushi HT, Davidson KW, et al. Tea and coffee brews are not dietary sources of vitamin K-1 (phylloquinone). J Am Diet Assoc 1995;95:82-3. PubMed
  13. Lou FQ, Zhang MF, Zhang XG, et al. A study on tea-pigment in prevention of atherosclerosis. Chin Med J (Engl) 1989;102:579-83.
  14. Graham HN. Green tea composition, consumption, and polyphenol chemistry. Prev Med 1992;21:334-50. PubMed
  15. Rapuri PB, Gallagher JC, Kinyamu HK, Ryschon KL. Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes. Am J Clin Nutr 2001;74:694-700. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Green Tea and Mitomycin Together: Common Questions

Is it safe to take Green Tea with Mitomycin?
We do not list a known interaction between Green Tea and Mitomycin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Green Tea and Mitomycin have any of the same side effects?
Yes — our sources link each of them separately to 10 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Green Tea and Mitomycin combination checked?
Interactions in our licensed database are recorded against drug classes. Mitomycin is filed under 3 classifications, and Green Tea has documented interactions with 58 drug classes — none of Mitomycin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Green Tea interact with any other medications?
Yes. Green Tea has 1,293 documented drug interactions in our database — Mitomycin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Mitomycin interact with any supplements?
Yes. Mitomycin has documented interactions with 26 supplements in our database — Green Tea is not one of them. The Mitomycin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Green Tea monograph Uses, safety profile, and every drug interaction in one place Mitomycin drug information The full plain-English guide to this medication Mitomycin supplement interactions Every supplement checked against Mitomycin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 219 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.