Drug & supplement interaction

Pinellia Ternata + Tioconazole

Tioconazole brand name: Vagistat.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Pinellia Ternata and Tioconazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Pinellia Ternata and Tioconazole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tioconazole and Pinellia Ternata in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Pinellia Ternata safety at a glance

Pinellia Ternata overall Use caution Raw Pinellia is toxic and irritating; only properly processed material used under professional guidance should be considered.
Pregnancy Avoid Traditionally cautioned against and lacking safety data, so it should be avoided in pregnancy.
Breastfeeding Avoid There is not enough safety information, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tioconazole and Pinellia Ternata? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Tioconazole

Interactions in our licensed database are recorded against drug classes, not just single drug names. Tioconazole is filed under 2 classifications — antifungals, oral drugs. Pinellia Ternata has documented interactions with 3 drug classes — the most serious being barbiturates (moderate), benzodiazepines (moderate) and cns depressants (moderate) — and none of Tioconazole’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Pinellia Ternata Does Interact With Other Medications

Pinellia Ternata has 256 moderate known drug interactions in our database — Tioconazole isn’t one of them. If you take anything else, check it against the full list below.

Moderate 256 No known interaction 2,574 (incl. Tioconazole)
Taking anything else?

Check Another of Your Medications Against Pinellia Ternata

Covers the 2,830 medications we’ve checked against Pinellia Ternata. Pick one to open its full report.

What to actually watch for

What Pinellia Ternata Itself Has Been Linked To

This is not an interaction — nothing below involves Tioconazole. It is the side-effect record for Pinellia Ternata on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Pinellia Ternata, this list is the first place to look. 3 entries are worth acting on rather than waiting out — marked below.

  • A heart attack / Raised blood pressure Worth acting on Additional detail

    “Pinellia ternata contains ephedrine alkaloids, which may potentially cause hypertension, tachycardia, and heart attack when used orally.”

    Pinellia Ternata · Natural Medicines adverse-effect record, reported in cardiac arrest.

    1 source cited
    1. 12147. FDA, HHS. Final rule declaring dietary supplements containing ephedrine alkaloids adulterated because they present an unreasonable risk. Fed Regist 2004;69:6787-6854.
  • Wheezing Worth acting on Additional detail

    “If Pinellia ternata preparations are inhaled they can cause IgE-mediated occupational asthma.”

    Pinellia Ternata · Natural Medicines adverse-effect record, reported in asthma.

    1 source cited
    1. 12145. Kim SH, Jeong H, Kim YK, et al. IgE-mediated occupational asthma induced by herbal medicine, Bahna (Pinellia ternata). Clin Exp Allergy 2000;31:779-81.
  • Seizures Worth acting on Additional detail

    “Pinellia ternata contains ephedrine alkaloids, which may potentially cause stroke and seizures when used orally.”

    Pinellia Ternata · Natural Medicines adverse-effect record, reported in epilepsy.

    1 source cited
    1. 12147. FDA, HHS. Final rule declaring dietary supplements containing ephedrine alkaloids adulterated because they present an unreasonable risk. Fed Regist 2004;69:6787-6854.
  • A fast or pounding heartbeat Additional detail

    Recorded for Pinellia Ternata in the same Natural Medicines adverse-effect record shown under A heart attack / Raised blood pressure above.

Everything above comes from the Natural Medicines adverse-effect record for Pinellia Ternata — expand a row for the licensed statement it rests on. We haven’t matched Tioconazole to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Tioconazole.

Everything else you take

See Every Supplement That Interacts With Tioconazole

This page covers Pinellia Ternata only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tioconazole page lists 20 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 12 minor.

From our pharmacist’s overview on the Tioconazole page

“Activated charcoal carries the only major rating among the 20 supplements flagged for tioconazole (Vagistat), and it is the pairing to sort out first. Charcoal binds many medications, lowering the amount that reaches the body, and this can happen regardless of how a drug is given.”

Reviewed by 2 · Jul 18, 2026

Open the Tioconazole interaction page

One more smart check

Taking Pinellia Ternata as Part of a Dietary Supplement Product? Check It for Interactions

We hold 20 real supplement products containing Pinellia Ternata, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Pinellia Ternata. Even though Pinellia Ternata itself has no known interaction with Tioconazole, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Pinellia Ternata and Tioconazole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Pinellia Ternata
Top half

#702 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tioconazole
Steady interest

#2,454 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pinellia Ternata reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Pinellia Ternata and Tioconazole records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Pinellia Ternata

What is Pinellia Ternata?

  • Nausea and vomiting
  • Cough with phlegm
  • Morning sickness (traditional use)
  • Digestive upset and bloating
  • Throat discomfort

Pinellia ternata is a tuber used in traditional Chinese medicine, most often for nausea, vomiting, and phlegmy coughs, and almost always as part of multi-herb formulas. The raw plant is toxic and must be specially processed before use, so it should only be used under qualified guidance. Solid human evidence is limited, and it should be avoided in pregnancy and breastfeeding.

Pinellia ternata · Araceae · Dried tuber (rhizome), usually processed before use · Dried processed tuber, powder, granules, decoctions (teas), and part of multi-herb traditional formulas

An interaction check asks whether these two react with each other — it does not ask whether Pinellia Ternata is a good idea for someone in your situation. Here is what our Pinellia Ternata record says about it on its own.

Pinellia Ternata: dosing

There is no well-established standardized dose of Pinellia ternata for supplement users. In traditional Chinese medicine it is given as processed tuber within specific multi-herb formulas, with the amount and preparation chosen by a trained practitioner.Because the raw herb is toxic and product quality varies, you should not try to dose this herb on your own. If you use a product, follow the label exactly and ideally work with a qualified practitioner.

From our Pinellia Ternata monograph — the full record covers uses, side effects and every documented interaction.

Read the full Pinellia Ternata monograph & all interactions
Medication

About Tioconazole

Most-Reported Side Effects for Tioconazole

From FAERS, the FDA’s public side-effect reporting system (1,541 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Vulvovaginal burning sensation 526 reports
Vulvovaginal swelling 295 reports
Vulvovaginal pain 229 reports
Vulvovaginal pruritus 197 reports
Vulvovaginal discomfort 161 reports
Keep checking

Other Drugs & Pinellia Ternata

Browse every other medication we’ve checked against Pinellia Ternata — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
256Moderate
0Minor
2,573No known interaction
256 Moderate 2,573 No interaction
Moderate

256 interactions

Showing 60 of 256 moderate interactions — see all 256 on the Pinellia Ternata page.

No interaction 2,573 drugs checked — show the list

We also checked Pinellia Ternata against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,573 medications checked with no known interaction — see the full Pinellia Ternata list.

See the full Pinellia Ternata interactions page
See every supplement checked against Tioconazole, ranked by severity
Evidence & sources

Pinellia Ternata References

The 4 references that drive our Pinellia Ternata monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Kim SH, Jeong H, Kim YK, et al. IgE-mediated occupational asthma induced by herbal medicine, Bahna (Pinellia ternata). Clin Exp Allergy 2000;31:779-81.
  2. FDA, HHS. Final rule declaring dietary supplements containing ephedrine alkaloids adulterated because they present an unreasonable risk. Fed Regist 2004;69:6787-6854.
  3. Lin S, Nie B, Yao G, Yang H, Ye R, Yuan Z. Pinellia ternata (Thunb.) makino preparation promotes sleep by increasing REM sleep. Nat Prod Res. 2019;33(22):3326-3329. PubMed
  4. Lin YH, Chen C, Zhao X, et al. Efficacy and Safety of Banxia Formulae for Insomnia: A Systematic Review and Meta-Analysis of High-Quality Randomized Controlled Trials. Evid Based Complement Alternat Med 2021;2021:8833168. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Pinellia Ternata and Tioconazole Together: Common Questions

Is it safe to take Pinellia Ternata with Tioconazole?
We do not list a known interaction between Pinellia Ternata and Tioconazole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Pinellia Ternata and Tioconazole combination checked?
Interactions in our licensed database are recorded against drug classes. Tioconazole is filed under 2 classifications, and Pinellia Ternata has documented interactions with 3 drug classes — none of Tioconazole's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Pinellia Ternata interact with any other medications?
Yes. Pinellia Ternata has 256 documented drug interactions in our database — Tioconazole is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Tioconazole interact with any supplements?
Yes. Tioconazole has documented interactions with 20 supplements in our database — Pinellia Ternata is not one of them. The Tioconazole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Pinellia Ternata monograph Uses, safety profile, and every drug interaction in one place Tioconazole supplement interactions Every supplement checked against Tioconazole, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Tioconazole and Pinellia Ternata?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.