Adipotrol Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Adipotrol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Adipotrol is a dietary supplement by Blackfire Global with 3 active ingredients. Its ingredients are commonly taken for weight loss and appetite control, constipation, high cholesterol.Based on those ingredients, 2,129 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glucomannan, Super CitriMax(R). Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Adipotrol by Blackfire Global
Ask about any prescription or over-the-counter medication and we check it for interactions with Adipotrol by Blackfire Global — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Adipotrol by Blackfire Global
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 3 of its 3 active ingredients.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 2 of the 2 matched ingredients can interact with medications — Glucomannan, Garcinia.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
- For scale: 2,130 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 2 of 2.
- General safety write-ups exist for 2 of 2.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 10, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Adipotrol, straight from the product label.
| Brand | Blackfire Global |
|---|---|
| Barcode (UPC) | 705105297743 |
| Net contents | 120 Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Oct 10, 2014 |
| DSLD ID | 37638 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Adipotrol by Blackfire Global, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Glucomannan | 500 mg | -- |
| Chromax | 30 mcg | 25% |
| Super CitriMax(R) | 778 mg | -- |
Other ingredients: vegetarian Glycerine
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Recommended use: Take 2-4 capsules with minimum of 16 ounces of water 30 minutes before meals to maximize effectiveness.
General Statements
Satisfaction Guaranteed: Freshness and safety sealed.
Consult with your physician before taking any new dietary supplement.
Non Prescription
Safe and Strong Appetite Suppressant
Trick the Brain to think the Body is Full and Satisfied Consume Fewer Calories
Rev. 003
Precautions
Do not use if seals are broken or missing.
WARNING: Keep this out of children’s reach. In case of an accidental overdose, seek professional assistance or contact a poison control center immediately.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product does not cure or prevent any diseases.
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Chromax(R) chromium picolinate
SuperCitramax(R)
Blackfire GLOBAL
Brand IP Statement(s)
(C)2012 Blackre Global, LLC
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Adipotrol by Blackfire Global label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Adipotrol by Blackfire Global
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Glucomannan
Interacts with2,022 drugs
Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and mo...
Glucomannan monograph & interactionsChromax
Super CitriMax(R)
Interacts with704 drugs
Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific eviden...
Super CitriMax(R) monograph & interactionsOther (inactive) ingredients: Vegetarian Glycerine. These complete the product’s ingredient list but are not active constituents.
Adipotrol by Blackfire Global Drug Interactions
Adipotrol contains 3 ingredients, and 2 of them have known drug interactions. Altogether they interact with 2,129 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Adipotrol?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Adipotrol interact with 2,129 drugs. Click any drug to see the details.
2 of the 3 ingredients in Adipotrol interact with drugs. Each result below shows which ingredient is responsible. Glucomannan Super CitriMax(R)
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Adipotrol — through 1 ingredient. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + 6-mercaptopurine interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Adipotrol — through 1 ingredient. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Abacavir Sulfate, Dolutegravir, Lamivudine interactionSuper Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Abacavir, Lamivudine interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Abciximab interactionSuper Citrimax(r)Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Super Citrimax(r) + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Adipotrol — through 1 ingredient. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Abiraterone interactionSuper Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Abiraterone Acetate interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Super Citrimax(r) + Abrocitinib interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Adipotrol — through 1 ingredient. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Adipotrol — through 1 ingredient. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Antidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Read the full Super Citrimax(r) + Acarbose interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acebutolol interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Super Citrimax(r) + Acenocoumarol interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Adipotrol — through 1 ingredient. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen interactionSuper Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Aspirin interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Anticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Super Citrimax(r) + Acetaminophen, Aspirin, Caffeine interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Butalbital interactionSuper Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Butalbital, Caffeine interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Butalbital, Caffeine, Codeine interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Butalbital, Codeine interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Butalbital, Codeine Phosphate interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Caffeine, Codeine interactionSuper Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Caffeine, Codeine, Salicylamide interactionSuper Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
Super Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Caffeine, Dihydrocodeine interactionGlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Adipotrol — through 2 ingredients. Tap an ingredient for the detail:
GlucomannanOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Acetaminophen, Caffeine, Isometheptene interactionSuper Citrimax(r)Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Super Citrimax(r) + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Adipotrol with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Glucomannan
Oral Drugs
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Due to its viscosity and bulking effects, there is concern that glucomannan can decrease the absorption of oral drugs. A small clinical study in healthy volunteers shows that taking glyburide 2.5 mg plus glucomannan 3.9 grams with breakfast reduces plasma levels of glyburide when compared with breakfast and glyburide alone. In addition, animal research demonstrates this effect on amoxicillin, but shows increased absorption of metronidazole. This mouse model also demonstrates that metronidazole elimination is prolonged, but amoxicillin elimination is enhanced by 38%; glucomannan may also affect the distribution of some drugs. To avoid changes in absorption, take glucomannan 30-60 minutes after taking oral drugs.
Super CitriMax(R)
Anticoagulant/Antiplatelet Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
HCA inhibits platelet aggregation in vitro. The inhibitory effect seems to be greater in platelets extracted from diabetic subjects than non-diabetic subjects.
Antidiabetes Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
HCA reduces fasting and postprandial blood glucose levels in animal models, theoretically by delaying glucose absorption. This effect has not been reported in humans.
Hepatotoxic Drugs
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
There have been reports of acute hepatitis with elevated liver enzymes associated with garcinia, when taken alone or in combination with other ingredients. Case reports collected from the Drug Induced Liver Injury Network suggest this risk may be greater in people who carry the HLA B*35:01 allele.
Serotonergic Drugs
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
In one report, a patient experienced serotonin syndrome after taking garcinia extract (60% hydroxycitric acid) 1000 mg daily in combination with escitalopram 20 mg, which had been taken for a year. The patient was switched to sertraline 50 mg daily and again experienced serotonin syndrome.
Brand information
Manufacturer and brand details for Adipotrol, from the product label.
Blackfire Global
See all Blackfire Global products- Name
- Blackfire Global, LLC
- City
- Provo
- State
- UT
- ZipCode
- 84604
Adipotrol by Blackfire Global: Common Questions
Does Adipotrol by Blackfire Global interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Adipotrol is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Adipotrol’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Glucomannan
Interacts with 2,022 drugsGlucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and modestly lowering cholesterol. It is gener...
Read the full Glucomannan monograph → Herb & supplement monographGarcinia
Interacts with 704 drugsGarcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific evidence is weak and mixed, with most studies...
Read the full Garcinia monograph →Sources & How We Checked
Adipotrol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 59 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Glucomannan 15 references
- Henry DA, Mitchell AS, Aylward J, et al. Glucomannan and risk of oesophageal obstruction. Br Med J 1986;292:591-2. PubMed
- Shima K, Tanaka A, Ikegami H, et al. Effect of dietary fiber, glucomannan, on absorption of sulfonylurea in man. Horm Metab Res 1983;15:1-3. PubMed
- Villaverde, A. F., Benlloch, S., Berenguer, M., Miguel, Rayon J., Pina, R., and Berenguer, J. Acute hepatitis of cholestatic type possibly associated with the use of glucomannan (amorphophalus konjac). J Hepatol. 2004;41(6):1061-1062. PubMed
- Yoshida, M., Vanstone, C. A., Parsons, W. D., Zawistowski, J., and Jones, P. J. Effect of plant sterols and glucomannan on lipids in individuals with and without type II diabetes. Eur.J Clin Nutr. 2006;60(4):529-537. PubMed
- Wood, R. J., Fernandez, M. L., Sharman, M. J., Silvestre, R., Greene, C. M., Zern, T. L., Shrestha, S., Judelson, D. A., Gomez, A. L., Kraemer, W. J., and Volek, J. S. Effects of a carbohydrate-restricted diet with and without supplemental soluble fiber
- Vanderbeek, P. B., Fasano, C., O'Malley, G., and Hornstein, J. Esophageal obstruction from a hygroscopic pharmacobezoar containing glucomannan. Clin Toxicol.(Phila) 2007;45(1):80-82. PubMed
- Bernstein, J. A., Crandall, M. S., and Floyd, R. Respiratory sensitization of a food manufacturing worker to konjac glucomannan. J Asthma 2007;44(8):675-680. PubMed
- Shichijo, K., Kobayashi, Y., Fueki, R., Shimoyama, K., and Masaya, M. [2 cases of konjac bronchial asthma found outside the "konnyaku" producing district]. Arerugi 1969;18(2):97-100.
- Carabin IG, Lyon MR, Wood S, et al. Supplementation of the diet with the functional fiber PolyGlycoplex is well tolerated by healthy subjects in a clinical trial. Nutr J 2009;8:9. PubMed
- Lyon MR, Reichert RG. The effect of a novel viscous polysaccharide along with lifestyle changes on short-term weight loss and associated risk factors in overweight and obese adults: an observational retrospective clinical program analysis. Altern Med Rev
- Lyon M, Wood S, Pelletier X, et al. Effects of a 3-month supplementation with a novel soluble highly viscous polysaccharide on anthropometry and blood lipids in nondieting overweight or obese adults. J Hum Nutr Diet 2011;24(4):351-9. PubMed
- Han Y, Zhang L, Liu XQ, Zhao ZJ, Lv LX. Effect of glucomannan on functional constipation in children: a systematic review and meta-analysis of randomised controlled trials. Asia Pac J Clin Nutr 2017;26(3):471-7.
- Health Canada Safety Alert. Health Canada Advises Canadians that natural health products containing glucomannan may cause serious choking if used with insufficient fluid. January 29, 2010. Alert # RA-110003825. https://healthycanadians.gc.ca/recall-alert-
- Mortensen A, Aguilar F, Crebelli, et al. EFSA Panel on Food Additives and Nutrient Sources added to Food. Re-evaluation of konjac gum (E 425 i) and konjac glucomannan (E425 ii) as food additives. EFSA Journal 2017;15(6):4864.
- Zhang Y, Aldamarany WAS, Song G, et al. Influence of konjac glucomannan and its derivatives on the oral pharmacokinetics of antimicrobial agent in antibiotics cocktails: Keep vigilant on dietary fiber supplement. Int J Biol Macromol 2023;251:126306. PubMed
Garcinia 44 references
- Heymsfield SB, Allison DB, Vasselli JR, et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA 1998;280:1596-600. PubMed
- Soni MG, Burdock GA, Preuss HG, et al. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol 2004;42:1513-29. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Willis SL, Moawad FJ, Hartzell JD, et al. Hypertensive retinopathy associated with use of the ephedra-free weight-loss herbal supplement Hydroxycut. MedGenMed 2006;8:82.
- Preuss HG, Bagchi D, Bagchi M, et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab 2004;6:171-180.
- Mansi IA, Huang J. Rhabdomyolysis in response to weight-loss herbal medicine. Am J Med Sci 2004;327:356-357. PubMed
- Lopez AM, Kornegay J, Hendrickson RG. Serotonin Toxicity Associated with Garcinia cambogia Over-the-counter Supplement. J Med Toxicol. 2014 Apr 4. [Epub ahead of print]. PubMed
- Michno A, Skibowska A, Raszeja-Specht A, Cwikowska J, Szutowicz A. The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus. Metabolism 2004;53(1):66-72. PubMed
- Asghar M, Monjok E, Kouamou G, et al. Super CitriMax (HCA-SX) attenuates increases in oxidative stress, inflammation, insulin resistance, and body weight in developing obese Zucker rats. Mol Cell Biochem 2007;304(1-2):93-99. PubMed
- Wielinga PY, Wachters-Hagedoorn RE, Bouter B, et al. Hydroxycitric acid delays intestinal glucose absorption in rats. Am J Physiol Gastrointest Liver Physiol 2005;288(6):G1144-G1149. PubMed
- Leonhardt M, Balkan B, Langhans W. Effect of hydroxycitrate on respiratory quotient, energy expenditure, and glucose tolerance in male rats after a period of restrictive feeding. Nutrition 2004;20(10):911-915. PubMed
- Bunchorntavakul, C. and Reddy, K. R. Review article: herbal and dietary supplement hepatotoxicity. Aliment.Pharmacol.Ther 2013;37(1):3-17. PubMed
- Vasques CA, Schneider R, Klein-Júnior LC, et al. Hypolipemic effect of Garcinia Cambogia in obese women. Phytother Res 2014;28(6):887-91.
- Marquez F, Babio N, Bullo M, Salas-Salvado J. Evaluation of the safety and efficacy of hydroxycitric acid or Garcinia cambogia extracts in humans. Crit Rev Food Sci Nutr 2012;52:585-94.
- Allen SF, Godley RW, Evron JM, et al. Acute necrotizing eosinophilic myocarditis in a patient taking Garcinia cambogia extract successfully treated with high-dose corticosteroids. Can J Cardiol 2014;30(12):1732 e13-1732 e15. PubMed
- Dara L, Hewett J, Lim JK. Hydroxycut hepatotoxicity: a case series and review of liver toxicity from herbal weight loss supplements. World J Gastroenterol. 2008 Dec 7;14(45):6999-7004. PubMed
- Sharma T, Wong L, Tsai N, Wong RD. Hydroxycut(®) (herbal weight loss supplement) induced hepatotoxicity: a case report and review of literature. Hawaii Med J. 2010 Aug;69(8):188-90.
- Rashid NN, Grant J. Hydroxycut hepatotoxicity. Med J Aust. 2010 Feb 1;192(3):173-4. PubMed
- Actis GC, Bugianesi E, Ottobrelli A, Rizzetto M. Fatal liver failure following food supplements during chronic treatment with montelukast. Dig Liver Dis. 2007 Oct;39(10):953-5. PubMed
- Corey R, Werner KT, Singer A, Moss A, Smith M, Noelting J, Rakela J. Acute liver failure associated with Garcinia cambogia use. Ann Hepatol. 2016 Jan-Feb;15(1):123-6. PubMed
- Melendez-Rosado J, Snipelisky D, Matcha G, Stancampiano F. Acute hepatitis induced by pure Garcinia cambogia. J Clin Gastroenterol. 2015 May-Jun;49(5):449-50. PubMed
- García-Cortés M, Robles-Díaz M, Ortega-Alonso A, Medina-Caliz I, Andrade RJ. Hepatotoxicity by Dietary Supplements: A Tabular Listing and Clinical Characteristics. Int J Mol Sci. 2016 Apr 9;17(4):537. PubMed
- Dehoney S, Wellein M. Rhabdomyolysis associated with the nutritional supplement Hydroxycut. Am J Health Syst Pharm. 2009;66(2):142-8. PubMed
- Fong TL, Klontz KC, Canas-Coto A, et al. Hepatotoxicity due to hydroxycut: a case series. Am J Gastroenterol. 2010;105(7):1561-6. PubMed
- Hendrickson BP, Shaikh N, Occhiogrosso M, Penzner JB. Mania Induced by Garcinia cambogia: A Case Series. Prim Care Companion CNS Disord. 2016;18(2).
- Kaswala D, Shah S, Patel N, Raisoni S, Swaminathan S. Hydroxycut-induced Liver Toxicity. Ann Med Health Sci Res. 2014; 4(1):143-5. PubMed
- Lobb A. Hepatoxicity associated with weight-loss supplements: a case for better post-marketing surveillance. World J Gastroenterol. 2009;15(14):1786-7. PubMed
- Lunsford KE, Bodzin AS, Reino DC, Wang HL, Busuttil RW. Dangerous dietary supplements: Garcinia cambogia -associated hepatic failure requiring transplantation. World J Gastroenterol. 2016;22(45):10071-10076.
- Narasimha A, Shetty PH, Nanjundaswamy MH, Viswanath B, Bada Math S. Hydroxycut - Dietary supplements for weight loss: Can they induce mania? Aust N Z J Psychiatry. 2013;47(12):1205-6. PubMed
- Shim M, Saab S. Severe hepatotoxicity due to Hydroxycut: a case report. Dig Dis Sci. 2009;54(2):406-8. PubMed
- Stohs SJ, Preuss HG, Ohia SE, et al. No evidence demonstrating hepatotoxicity associated with hydroxycitric acid. World J Gastroenterol. 2009;15(32):4087-9. PubMed
- Gavril A, Ribnikar M, Smid L, Luzar B, Stabuc B. Fat burner-induced acute liver injury: case series of four patients. Nutrition. 2018;47:110-114. doi: 10.1016/j.nut.2017.10.002. PubMed
- Bystrak T, Cervera-Hernandez ME, Reddy N, King Z, Bratberg J. Garcinia cambogia, diabetic ketoacidosis, and pancreatitis. R I Med J (2013). 2017 Oct 2;100(10):48-50. NO DOI
- Smith RJ, Bertilone C, Robertson AG. Fulminant liver failure and transplantation after use of dietary supplements. Med J Aust. 2016;204(1):30-2. PubMed
- Nguyen DC, Timmer TK, Davison BC, McGrane IR. Possible Garcinia cambogia-induced mania with psychosis: a case report. J Pharm Pract 2019;32(1):99-102. doi: 10.1177/0897190017734728.
- Yousaf MN, Chaudhary FS, Hodanazari SM, Sittambalam CD. Hepatotoxicity associated with Garcinia cambogia: a case report. World J Hepatol 2019;11(11):735-42.
- Mas Ordeig A, Bordón García N. Hepatotoxicity caused by Garcinia cambogia. Gastroenterol Hepatol 2020;43(3):134-5. DOI
- Cho HK, Han YS, Park JM. Ocular complications of Garcinia cambogia extract diet pills: case report. Eur J Ophthalmol 2019:1120672119872364. PubMed
- Ferreira V, Mathieu A, Soucy G, Giard JM, Erard-Poinsot D. Acute severe liver injury related to long-term Garcinia cambogia intake. ACG Case Rep J. 2020;7(8):e00429. PubMed
- Iqbal U, Anwar H, Siddiqui HU, Mehmood A. Acute Pancreatitis Secondary to Use of Appetite Suppressant: Garcinia cambogia. Cureus. 2019;11(5):e4676. PubMed
- Grigos A, Benmoussa J, Sandhu J, Chaucer B, Clarke M, SH Patel. Acute pancreatitis secondary to Garcinia cambogia; the unknown cost of herbal supplements. JOP. J Pancreas (Online) 2016; 17(3):316-317.
- Sidhu RLS, Labana S, Khehra L. Garcinia cambogia: a link between the "miracle" weight loss pill and acute pancreatitis. Am J Gastroenterol. 2016. 111:S560-S561. DOI
- Vuppalanchi R, Bonkovsky HL, Ahmad J, et al. Garcinia cambogia, Either Alone or in Combination With Green Tea, Causes Moderate to Severe Liver Injury. Clin Gastroenterol Hepatol 2021. PubMed
- Calaquian LL, Yau I. Garcinia cambogia-A Supplement-Related Liver Injury. Cureus 2022;14(2):e22225. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC