Aloe Vera Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Aloe Vera against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Aloe Vera is a dietary supplement by Mason Natural with 1 active ingredient. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 461 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Aloe Vera Gel 200:1 extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Aloe Vera by Mason Natural
Ask about any prescription or over-the-counter medication and we check it for interactions with Aloe Vera by Mason Natural — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Aloe Vera by Mason Natural
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Aloe Vera Gel 200:1 extract, a concentrated form of the inner gel of the aloe plant. The remaining ingredients are inactive — soybean oil, gelatin, vegetable glycerin, cottonseed oil, white beeswax, and purified water — which make up the softgel capsule and help deliver the extract.
Does it work?
Moderate evidence
The data shows aloe gel is possibly effective for acne, obesity, diabetes, psoriasis, burns, and constipation. These are preliminary findings, so the evidence isn't conclusive yet, but there's reason to think it may help with these conditions.
Talk with your pharmacist about whether it fits your goals.
How safe is it?
Well-documented data
Oral aloe latex can cause serious side effects, especially at high doses or with long-term use. The most common ones are abdominal pain, cramps, and diarrhea.
In rare cases, long-term or excessive use can lead to low potassium (hypokalemia), muscle weakness, and irregular heartbeat. Do not take aloe by mouth during pregnancy — the latex may trigger contractions and act as a strong laxative.
Avoid it while breastfeeding as well; there isn't enough safety data and the laxative effects are a concern.
Meds to double-check
Major interaction found
Before taking this, double-check with your pharmacist if you're on digoxin or other heart medications, blood thinners or antiplatelet drugs, diabetes medications, diuretics, warfarin, stimulant laxatives, or drugs metabolized by your liver's CYP1A2 enzyme. The interactions range from Major to Minor severity.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Aloe gel is generally well tolerated for short-term use, but it's not a grab-and-go supplement if you take heart, blood-clotting, diabetes, or blood-pressure medications. If you're on any prescription drugs — especially digoxin, warfarin, or diuretics — check with your pharmacist first.
Pregnant or breastfeeding? Skip this one.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Aloe Vera, straight from the product label.
| Brand | Mason Natural |
|---|---|
| Barcode (UPC) | 311845121752 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Feb 26, 2020 |
| DSLD ID | 214587 |
| Product type | Botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Aloe Vera by Mason Natural, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Aloe Vera Gel 200:1 extract | 25 mg | -- |
Other ingredients: Soybean Oil, Gelatin, Vegetable Glycerin, Cottonseed Oil, White Beeswax, purified Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols
Mason Guarantee Laboratory Tested cGMP Certified Good Manufacturing Practice Certified
General Statements
Mason Natural Est. 1967
Formulation
May support digestion & regularity
Color variation is possible.
Guaranteed No Added: Artificial color, flavor or sweetener, preservatives, sugar, starch, milk, lactose, wheat, yeast, fish. Sodium free.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Adults - Take one softgel, one to three times daily, preferably with food, as a dietary supplement.
Formula
Contains naturally harvested herbal products.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Allergen Certification - This product contains soy.
Warning: If you are pregnant, nursing, taking any medications or planning any medical procedure, consult your physician before use.
Discontinue use and consult your physician if any adverse reactions occur.
Keep out of reach of children.
Tamper-evident seal: Do not use product if seal appears tampered.
Storage
Store in a dry place under controlled room temperature: 20 degrees - 25 degrees C (68 degrees - 77 degrees F).
Brand IP Statement(s)
Mason Natural is a registered trademark and does not refer to any product or ingredient claim.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Aloe Vera by Mason Natural label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Aloe Vera by Mason Natural
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Aloe Vera Gel 200:1 extract
Interacts with461 drugs
Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...
Aloe Vera Gel 200:1 extract monograph & interactionsOther (inactive) ingredients: Soybean Oil, Gelatin, Vegetable Glycerin, Cottonseed Oil, White Beeswax, Purified Water. These complete the product’s ingredient list but are not active constituents.
Aloe Vera by Mason Natural Drug Interactions
HelloPharmacist Interaction Report
Mason Natural's Aloe Vera Gel extract interacts with several medication types, with the most serious concern being digoxin (Lanoxin), a heart medication.
Overuse of aloe latex can deplete potassium, which compounds the risk of toxicity when you're taking digoxin. This is a Major severity interaction and worth a careful conversation with your pharmacist or doctor before starting.
Read the full breakdown — every affected drug type, severity by severity
Aloe also carries Moderate interactions with blood thinners (anticoagulants) and antiplatelet drugs — the gel can slow blood clotting in lab studies, raising bleeding risk. Similarly, warfarin (Coumadin) users should be cautious because aloe's laxative effect can trigger diarrhea, which boosts warfarin's potency and bleeding risk.
If you take diabetes medications, monitor your blood sugar closely; aloe may lower it further. Diuretics and aloe don't mix well either, as both can drop your potassium dangerously low.
Avoid combining aloe with other stimulant laxatives due to fluid and electrolyte loss.
Aloe may also decrease the effectiveness of certain drugs processed by your liver's CYP1A2 enzyme (a Minor interaction). Altogether, these interactions span 460 individual medications.
Check your exact medications with the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Aloe Vera?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Aloe Vera interact with 461 drugs. Click any drug to see the details.
1 of the 1 ingredient in Aloe Vera interact with drugs. Each result below shows which ingredient is responsible. Aloe Vera Gel 200:1 extract
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractDigoxin (lanoxin) Major
Interaction Summary
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Read the full Aloe Vera Gel 200:1 Extract + Digoxin interactionAbciximabReoPro
How Abciximab interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Extract + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Gel 200:1 Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Gel 200:1 Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Gel 200:1 Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel 200:1 Extract + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Extract + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel 200:1 Extract + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel 200:1 Extract + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Extract + Argatroban interactionArmodafinilNuvigil
How Armodafinil interacts with Aloe Vera — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 ExtractStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Aloe Vera Gel 200:1 Extract + Armodafinil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Aloe Vera with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Aloe Vera Gel 200:1 extract
Digoxin (Lanoxin)
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.
Anticoagulant/Antiplatelet Drugs
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.
Antidiabetes Drugs
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.
Diuretic Drugs
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.
Stimulant Laxatives
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Aloe Vera, from the product label.
Mason Natural
See all Mason Natural products- Name
- Mason Vitamins, Inc.
- City
- Miami Lakes
- State
- FL
- ZipCode
- 33014
- Phone Number
- 1-888-860-5376
- Web Address
- www.MasonVitamins.com
Aloe Vera by Mason Natural: Common Questions
Does Aloe Vera by Mason Natural interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is the 200:1 extract mean on the label?
Can I use this long-term?
Will this help my diabetes?
What are the side effects I should watch for?
Is this safe during pregnancy?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Aloe Vera is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Aloe Vera’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Aloe Vera's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Aloe 41 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
- Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
- Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
- Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
- Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
- Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
- Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
- Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
- Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
- Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
- Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
- Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
- Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6
- Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279.
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