Major interaction on record — check this product against your medications before combining. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Collagen Creamer Original Ingredients & Drug Interactions

by Orgain

Collagen Creamer Original label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Collagen Creamer Original against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Collagen Creamer Original is a dietary supplement by Orgain with 6 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis prevention, dietary calcium deficiency, heartburn relief (calcium carbonate antacids).Based on those ingredients, 352 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Caprylic Acid, Calcium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Collagen Creamer Original by Orgain

Ask about any prescription or over-the-counter medication and we check it for interactions with Collagen Creamer Original by Orgain — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Collagen Creamer Original by Orgain

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “Medium Chain Triglyceride Oil” is listed as a grouped ingredient — the label gives one combined amount (1.50 Gram(s)) without saying how much of each component you get.

Orgain Collagen Creamer Original contains 5 active ingredients. Calcium is included for bone and mineral support.

Caprylic acid, capric acid, and lauric acid are medium-chain fatty acids derived from coconut oil. Collagen peptides are hydrolyzed collagen — broken-down collagen protein — intended to support skin and connective tissue.

The product also contains several inactive ingredients (fillers and binders) including oat powder, coconut oil, acacia gum, calcium carbonate, sunflower lecithin, guar gum, xanthan gum, avocado oil, cocoa butter, and vitamin E acetate.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Support hair, skin, nails and joints.
  • We looked for evidence on: Aging skin, Androgenic alopecia, Brittle nails, Cellulite, Dermatoporosis, Dry skin — and 4 related terms.
  • The strongest evidence on file: Collagen Peptides is rated "Possibly Effective" for Aging skin (Natural Medicines).
  • Also on file: Collagen Peptides is rated "Possibly Effective" for Dry skin.
  • Also on file: Calcium is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.

Calcium in this product is backed by solid evidence for several uses. It's effective for preventing and treating low blood calcium (hypocalcemia), supporting bone health in osteoporosis, managing high potassium levels (hyperkalemia), and treating indigestion (dyspepsia).

For the fatty acids — caprylic acid, capric acid, and lauric acid — the evidence we hold is insufficient to establish whether they work for epilepsy, essential tremor, bronchitis, vaginal yeast infections, colds, or genital herpes. Collagen peptides show possibly effective evidence for aging skin and dry skin, but the data suggests they are possibly ineffective for muscle strength.

Evidence for collagen peptides in acne and athletic performance is insufficient.

The evidence, ingredient by ingredient Calcium Collagen Peptides Caprylic Acid Lauric Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Calcium is generally well tolerated at recommended doses, though high doses can cause problems. The most common side effects are belching, constipation, diarrhea, flatulence, and stomach upset.

Rarely, case reports have raised concerns about calciphylaxis and kidney stones. Some epidemiological evidence suggests that consuming over 2000 mg per day of dietary calcium might increase the risk of prostate cancer; additional research suggests doses over 1500 mg daily might increase the risk of advanced prostate cancer and prostate cancer mortality.

There has also been concern about very high calcium intake and increased risk of heart disease, though research on this is mixed and criticized. Caprylic acid is generally recognized as safe in food amounts, but supplement doses lack strong safety data.

It may cause mild abdominal discomfort, taste changes, and rarely dizziness, headache, or fatigue. Lauric acid at high doses may increase total cholesterol and LDL cholesterol, though it also increases HDL cholesterol.

Nausea can occur when lauric acid is consumed in certain amounts. Collagen peptides are generally well tolerated; rare side effects include nausea, indigestion, diarrhea, and gas.

Side effects, ingredient by ingredient Calcium Collagen Peptides Caprylic Acid Lauric Acid

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 4 matched ingredients can interact with medications — Calcium, Caprylic Acid.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications; lithium.
  • For scale: 352 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this product if you use dolutegravir (Tivicay), elvitegravir (Vitekta), or intravenous ceftriaxone (Rocephin) — calcium poses Major-severity risks with these. Also double-check if you take raltegravir (Isentress), levothyroxine (Synthroid), sotalol (Betapace), diltiazem (Cardizem), calcipotriene (Dovonex), blood pressure medications, NSAIDs, or warfarin (Coumadin) — these carry Moderate-severity theoretical interactions.

No interactions are documented in our data for capric acid.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Calcium in this creamer makes it useful if you need bone support or treat low blood calcium, but it's a major concern if you take HIV integrase inhibitors, ceftriaxone, or levothyroxine. Check your medications with the tool on this page before starting.

Pregnant women should stay within recommended calcium amounts. Overall, the product is generally well tolerated, but talk with your pharmacist about whether it's right for your specific health situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Collagen Creamer Original, straight from the product label.

Brand Orgain
Barcode (UPC) 851770008235
Net contents 10 Ounce(s); 283.5 Gram(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 314868
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Collagen Creamer Original by Orgain, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Gram(s)
Maximum serving Sizes:
20 Gram(s)
Servings per container
14
UPC/BARCODE
851770008235
IngredientAmount% DV
Calories80 Calorie(s)--
Total Carbohydrates6 Gram(s)2%
Calcium230 mg20%
Caprylic Acid0.9 Gram(s)--
Capric Acid0.6 Gram(s)--
Lauric Acid0.02 Gram(s)--
Added Sugars0 Gram(s)--
Total Sugars1 Gram(s)--
Total Fat2 Gram(s)3%
Saturated Fat1.5 Gram(s)8%
Protein10 Gram(s)--
Collagen Peptides10 Gram(s)--
Medium Chain Triglyceride Oil1.5 Gram(s)--

Other ingredients: Oat, Hydrolyzed, Powder, Coconut Oil, Acacia Gum, Calcium Carbonate, Sunflower Lecithin, Guar Gum, Xanthan Gum, Avocado Oil, Cocoa Butter, Vitamin E Acetate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Non-dairy

Cleaner ingredients Higher standards

No dairy ingredients No soy ingredients Non-GMO tested Gluten free No artificial flavors or colors

Hair, skin, nail & joint support

Igen Non-GMO tested

Brand IP Statement(s)

Orgain Good, clean nutrition

Copyright 2022 Orgain, LLC

Formula

Powders made from Type I and III grass-fed and pasture-raised collagen peptides Oat powder Coconut oil Avocado oil 1g Sugar Per serving

Add this non-dairy, oatmilk creamer for a silky smooth cup that's powered with 10g of collagen to support hair, skin, nails and joints. It's a good, clean wake-up call that fills your cup with nutrition. The scoop: 10g grass-fed collagen, oatmilk, and MCTs.

Collagen Creamer with oatmilk powder Made with MCT OIL

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Get more glow from your cup of Joe. Give your coffee a clean start.

Typical Amino Acid Profile (average milligrams per serving naturally occurring) Alanine 780mg Arginine 670mg Aspartic Acid 510mg Glutamic Acid 900mg Glycine 2095mg Histidine 55mg Hydroxylysine 85mg Hydroxyproline 1025mg Isoleucine 130mg Leucine 255mg Lysine 335mg Methionine 65mg Phenylalanine 160mg Proline 1240mg Serine 305mg Threonine 170mg Tyrosine 40mg Valine 180mg Essential amino acids

Our Commitment to Clean Nutrition Orgain’s relentless pursuit of better nutrition that doesn’t compromise on taste is based on my belief that real foods can make a real difference. That passion fuels our mission to help people live vibrant lives through good, clean nutrition. In good health, Andrew Abraham, M.D. Founder, Cancer Survivor & Food Entrepreneur

Facebook Instagram Pinterest Orgain.com See website for product details. Questions about Orgain products? 888-881-GAIN (4246)

Suggested/Recommended/Usage/Directions

Suggested usage Combine one scoop with approximately 8-10oz coffee or tea. Stir well.

FDA Statement of Identity

Dietary Supplement

Precautions

Contains: Coconuts (tree nuts)

If you are pregnant, nursing or have a medical condition, consult your physician before use.

Storage

Storage Information: Store in a cool, dry place with lid tightly sealed. Avoid exposure to light, heat, and moisture.

Seals/Symbols

Igen Non-GMO tested

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Collagen Creamer Original by Orgain label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Collagen Creamer Original label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Collagen Creamer Original by Orgain

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size20 Gram(s) Dosage formPowder Servings per container14 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Calcium

Interacts with
168 drugs
230 mg per serving Form: Calcium Carbonate

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

Protein

10 Gram(s) per serving

Collagen Peptides

No known
interactions
10 Gram(s) per serving Form: Bovine

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is...

Collagen Peptides monograph & interactions

Medium Chain Triglyceride Oil

1.5 Gram(s) per serving Form: Coconut Oil

Other (inactive) ingredients: Oat, Hydrolyzed, Powder, Coconut Oil, Acacia Gum, Calcium Carbonate, Sunflower Lecithin, Guar Gum, Xanthan Gum, Avocado Oil, Cocoa Butter, Vitamin E Acetate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Collagen Creamer Original by Orgain Drug Interactions

Want to check YOUR meds against Collagen Creamer Original?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
352Drugs
7 Major 343 Moderate 2 Minor

Ingredients driving the most interactions

Caprylic Acid 262
Calcium 168

Individual Drug Interactions

The ingredients in Collagen Creamer Original interact with 352 drugs. Click any drug to see the details.

2 of the 6 ingredients in Collagen Creamer Original interact with drugs. Each result below shows which ingredient is responsible. Caprylic Acid Calcium

Each ingredient & the kinds of drugs it affects

For each ingredient in Collagen Creamer Original with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Caprylic Acid3 drug types · 262 drugs

Antihypertensive Drugs

Theoretically, caprylic acid might increase the risk of hypotension when used with antihypertensive drugs.
Animal research suggests that caprylic acid might have positive inotropic effects, resulting in reduced arterial pressure and vascular resistance and increased cardiac output.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

Theoretically, caprylic acid might increase plasma concentrations of NSAIDs.
In vitro research suggests that caprylic acid might displace NSAIDs from binding sites on albumin. This effect has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, caprylic acid might increase plasma concentrations of warfarin.
In vitro research suggests that high doses of caprylic acid might displace warfarin from albumin binding sites. This effect has not been reported in humans.

Likelihood Possible Evidence D
Caprylic Acid full monograph & interactions

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Calcium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Collagen Creamer Original, from the product label.

Orgain

See all Orgain products
Name
Orgain, LLC
Street Address
PO Box 4918
City
Irvine
State
CA
ZipCode
92616
Phone Number
888-881-4246
Web Address
orgain.com
Pharmacist Counseling Corner

Collagen Creamer Original by Orgain: Common Questions

Does Collagen Creamer Original by Orgain interact with any medications?
Yes. Based on its ingredients, Collagen Creamer Original has a known interaction with 352 medications, including 7 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Collagen Creamer Original contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy?
Calcium is likely safe in pregnancy when you stay within recommended amounts — adequate calcium is important for you and your baby. Lauric acid is also likely safe. However, caprylic acid and collagen peptides lack sufficient safety data in pregnancy, so talk with your doctor before using those. Check with your doctor or pharmacist about your individual situation.
Is this safe while breastfeeding?
Calcium at recommended amounts is fine during breastfeeding. Lauric acid occurs naturally in breast milk and is likely safe. Caprylic acid and collagen peptides have not been well studied during breastfeeding, so caution is advised — talk with your doctor or pharmacist before using them.
What side effects might I notice?
The most common side effects from calcium are belching, constipation, diarrhea, gas, and stomach upset. Caprylic acid may cause mild stomach discomfort and taste changes, rarely dizziness, headache, or fatigue. Collagen peptides rarely cause nausea, indigestion, diarrhea, or gas. Lauric acid at higher doses may increase nausea.
Does this actually work for skin and aging?
Collagen peptides have possibly effective evidence for aging skin and dry skin, so there's some research backing those uses. However, the data is limited. For other claimed uses of the fatty acids — like colds, bronchitis, or genital herpes — the evidence we hold is insufficient to say whether they work.
Will this interact with my blood pressure medication?
Caprylic acid in this product could theoretically increase the risk of low blood pressure if you're on blood pressure medication, though this hasn't been proven in humans. Calcium itself doesn't pose that risk. Use the medication checker on this page to look up your specific drug, or talk with your pharmacist.
Can I take this with my thyroid medication?
Calcium can interfere with how well levothyroxine (Synthroid) is absorbed, so if you take thyroid medication, separate it from this creamer by at least 4 hours — take your thyroid pill either before breakfast or well after a meal containing this product. Check with your pharmacist about your specific medication.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Collagen Creamer Original is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Collagen Creamer Original label
Go deeper

The Full Monographs Behind Collagen Creamer Original’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph → Herb & supplement monograph

Collagen Peptides

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is still developing and results vary. They...

Read the full Collagen Peptides monograph → Herb & supplement monograph

Caprylic Acid

Interacts with 262 drugs

Caprylic acid is a medium-chain fatty acid found in coconut oil and palm kernel oil that is popularly used for yeast overgrowth and gut health. While laboratory studies show it has antimicro...

Read the full Caprylic Acid monograph → Herb & supplement monograph

Lauric Acid

Lauric acid is a medium-to-long-chain saturated fatty acid found in coconut oil, palm kernel oil, and breast milk. It is studied for possible antimicrobial and skin benefits, but solid human...

Read the full Lauric Acid monograph →
Sources

Sources & How We Checked

Collagen Creamer Original's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 77 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Calcium 62 references
  1. Shils M, Olson A, Shike M. Modern Nutrition in Health and Disease. 8th ed. Philadelphia, PA: Lea and Febiger, 1994.
  2. Hernandez-Avila M, Gonzalez-Cossio T, Hernandez-Avila JE, et al. Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial. Epidemiology 2003;14:206-12.. PubMed
  3. Thys-Jacobs S, Ceccarelli S, Bierman A, et al. Calcium supplementation in premenstrual syndrome: a randomized crossover trial. J Gen Intern Med 1989;4:183-9. PubMed
  4. Maton PN, Burton ME. Antacids revisited: a review of their clinical pharmacology and recommended therapeutic use. Drugs 1999;57:855-70.
  5. Clemens JD, Feinstein AR. Calcium carbonate and constipation: a historical review of medical mythopoeia. Gastroenterology 1977;72:957-61. DOI
  6. Saunders D, Sillery J, Chapman R. Effect of calcium carbonate and aluminum hydroxide on human intestinal function. Dig Dis Sci 1988;33:409-13. PubMed
  7. Friedman PA, Bushinsky DA. Diuretic effects on calcium metabolism. Semin Nephrol 1999;19:551-6.
  8. Koo WK, Walters JC, Esterlitz J, et al. Maternal calcium supplementation and fetal bone mineralization. Obstet Gynecol 1999;94:577-82. DOI
  9. Raman L, Rajalakshmi K, Krishnamachari KAVR, et al. Effect of calcium supplementation to undernourished mothers during pregnancy on the bone density of the neonates. Am J Clin Nutr 1978; 31:466-9. DOI
  10. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  11. Chan JM, Giovannucci E, Andersson SO, et al. Dairy products, calcium, phosphorous, vitamin D, and risk of prostate cancer. Cancer Causes Control 1998;9:559-66.
  12. Butner LE, Fulco PP, Feldman G, et al. Calcium carbonate-induced hypothyroidism. Ann Intern Med 2000:132:595. PubMed
  13. Schneyer CR. Calcium carbonate and reduction of levothyroxine efficacy. JAMA 1998;279:750. PubMed
  14. Moser LR, Smythe MA, Tisdale JE. The use of calcium salts in the prevention and management of verapamil-induced hypotension. Ann Pharmacother 2000;34:622-9. PubMed
  15. Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA 2000;283:2822-5. PubMed
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Caprylic Acid 5 references
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Lauric Acid 8 references
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See these in context on the Lauric Acid monograph →

Collagen Peptides 2 references
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  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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