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Dietary supplement

Digesten-K Ingredients & Drug Interactions

by XtendLife

Digesten-K label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Digesten-K against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Digesten-K is a dietary supplement by XtendLife with 2 active ingredients. Its ingredients are commonly taken for constipation and digestive health, vitamin c and antioxidant support, sleep support.Based on those ingredients, 289 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Digesten-K. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Digesten-K by XtendLife

Ask about any prescription or over-the-counter medication and we check it for interactions with Digesten-K by XtendLife — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Digesten-K by XtendLife

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Digesten-K contains two active ingredients: Digesten-K and kiwifruit powder—both derived from kiwi. The product also includes vegetarian capsules, microcrystalline cellulose (a binder), and silicon dioxide (an anti-caking agent) as inactive ingredients.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Kiwi product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Kiwi's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“support healthy digestion”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence isn't established in our data for the claims associated with this product. For asthma, constipation, high blood pressure, and IBS, the ratings are insufficient reliable evidence to determine whether kiwi in this form actually works.

The evidence, ingredient by ingredient Kiwi

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Kiwi fruit eaten as food is generally well tolerated, but this is a concentrated supplement, which hasn't been well studied. Some people develop allergic reactions to kiwi—ranging from lip and mouth swelling, difficulty swallowing (dysphagia), hives, and rash to nausea, diarrhea, and vomiting that can happen right after eating or drinking it.

In rare cases, anaphylaxis and severe asthma flare-ups have been reported. Talk to your doctor before using this supplement, especially if you've had any reaction to kiwi fruit in the past.

For pregnancy and breastfeeding, the safety data rates kiwi as likely safe, but because this is a supplement-strength product rather than whole food, discuss it with your doctor or pharmacist before use during pregnancy or while nursing.

Side effects, ingredient by ingredient Kiwi

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Kiwi.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 289 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Digesten-K, check with your doctor or pharmacist if you take any blood thinners or antiplatelet drugs (aspirin, warfarin, clopidogrel, enoxaparin, heparin, or others) or blood pressure medications (captopril, enalapril, losartan, and similar ACE inhibitors or ARBs). Kiwi may increase bleeding risk and lower blood pressure further when combined with these drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Digesten-K is a kiwi-based supplement with no proven effectiveness for its claimed uses in our data. If you take blood pressure or blood-thinning medications, you'll need to clear this with your doctor or pharmacist first—the interactions are real and could affect how your drugs work.

If you have any history of kiwi allergy or fruit sensitivities, avoid it and talk it over with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digesten-K, straight from the product label.

Brand XtendLife
Net contents 60 Vegetarian Capsules
Market status On market
Date entered into DSLD Nov 25, 2011
DSLD ID 732
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digesten-K by XtendLife, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
IngredientAmount% DV
Digesten-K250 mg--
Kiwifruit powder250 mg--

Other ingredients: Vegetarian Capsules, Microcrystalline Cellulose, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

The above-mentioned bioactives in Digesten-K(R) have been shown to support healthy digestion.

The triple extracted Digesten-K(R) has been optimised to provide maximum enzyme, phenolic and soluble fibre content of kiwifruit flesh, skin, and seeds.

This 50/50 blend is comprised of a special triple extract of kiwifruit (known as Digesten-K(R)) and kiwifruit powder.

Formulation

Does not contain any other additives.

Storage

Store in a cool, dry, place.

General Statements

Best Quality Guarantee

Dietary Supplement Product of New Zealand

love life. live life.

Product of New Zealand

Pure New Zealand Kiwifruit Extract

XTEND-LIFE(TM) Digesten-K(R) is a 100% natural extract produced in New Zealand from pure green NZ grown kiwifruit.

General

L1246-1 110517

Suggested/Recommended/Usage/Directions

Directions For Use: Adults: 1 capsule after a meal, once or twice daily.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Digesten-K by XtendLife label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Digesten-K label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Digesten-K by XtendLife

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Digesten-K

Interacts with
289 drugs
250 mg per serving

Kiwi is a nutritious fruit that is rich in vitamin C, fiber, and antioxidants, and it is generally safe to eat as a food. The strongest evidence is fo...

Digesten-K monograph & interactions

Kiwifruit powder

Interacts with
289 drugs
250 mg per serving

Kiwi is a nutritious fruit that is rich in vitamin C, fiber, and antioxidants, and it is generally safe to eat as a food. The strongest evidence is fo...

Kiwifruit powder monograph & interactions

Other (inactive) ingredients: Vegetarian Capsules, Microcrystalline Cellulose, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digesten-K by XtendLife Drug Interactions

Want to check YOUR meds against Digesten-K?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
289Drugs
289 Moderate

Ingredients driving the most interactions

Digesten-K 289

Individual Drug Interactions

The ingredients in Digesten-K interact with 289 drugs. Click any drug to see the details.

1 of the 2 ingredients in Digesten-K interact with drugs. Each result below shows which ingredient is responsible. Digesten-K

Each ingredient & the kinds of drugs it affects

For each ingredient in Digesten-K with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Digesten-K2 drug types · 289 drugs

Anticoagulant/Antiplatelet Drugs

Clinical research suggests that kiwi inhibits platelet aggregation. Theoretically, kiwi might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Antihypertensive Drugs

Clinical research suggests that consuming kiwi reduces systolic and diastolic blood pressure in hypertensive individuals. Theoretically, concomitant use of kiwi and antihypertensive drugs may increase the risk of hypotension when used in combination with drugs that lower blood pressure. These include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.

Likelihood Possible Evidence D
Digesten-K full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Digesten-K, from the product label.

XtendLife

Web Address
www.xtend-life.com
Pharmacist Counseling Corner

Digesten-K by XtendLife: Common Questions

Does Digesten-K by XtendLife interact with any medications?
Yes. Based on its ingredients, Digesten-K has a known interaction with 289 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Digesten-K contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product actually work for constipation, asthma, or IBS?
We don't have enough reliable evidence to say whether kiwi in supplement form works for any of those uses. The ratings across asthma, constipation, high blood pressure, and IBS are all insufficient evidence.
Can I take this if I'm allergic to kiwi fruit?
No. Kiwi allergies can cause serious reactions—swelling of the lips, mouth, and throat; difficulty swallowing; hives; nausea; vomiting; and in rare cases, anaphylaxis or asthma flare-ups. If you've ever reacted to kiwi, don't use this product.
Is it safe to take while pregnant or breastfeeding?
The safety data rates kiwi as likely safe during pregnancy and lactation, but because this is a concentrated supplement rather than whole fruit, talk with your doctor or pharmacist before using it during pregnancy or while nursing.
What are the side effects I might notice?
Kiwi is generally well tolerated, but some people experience allergic reactions of the lips, mouth, and throat (including swelling, rash, and difficulty swallowing), along with nausea, diarrhea, or vomiting right after taking it. Rare but serious reactions include anaphylaxis and asthma exacerbation.
Why does the label say this is for digestion if the evidence doesn't support it?
That's a fair question—the evidence we have doesn't establish that kiwi works for constipation, IBS, or other digestion issues. The product name and claims aren't backed by reliable clinical data in our records.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digesten-K is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digesten-K label
Go deeper

The Full Monographs Behind Digesten-K’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Kiwi

Interacts with 289 drugs

Kiwi is a nutritious fruit that is rich in vitamin C, fiber, and antioxidants, and it is generally safe to eat as a food. The strongest evidence is for helping with constipation and overall...

Read the full Kiwi monograph →
Sources

Sources & How We Checked

Digesten-K's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 32 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Kiwi 32 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Diez-Gomez ML, Quirce S, Aragoneses E, Cuevas M. Asthma caused by Ficus benjamina latex: evidence of cross-reactivity with fig fruit and papain. Ann Allergy Asthma Immunol 1998;80:24-30.
  3. Forastiere F, Pistelli R, Sestini P, et al. Consumption of fresh fruit rich in vitamin C and wheezing symptoms in children. Thorax 2000;55:283-8. DOI
  4. Carey IM, Strachan DP, Cook DG. Effects of changes in fresh fruit consumption on ventilatory function in healthy British adults. Am J Respir Crit Care Med 1998;158:728-33. PubMed
  5. Schwartz J, Weiss ST. Relationship between dietary vitamin C intake and pulmonary function in the First National Health and Nutrition Examination Survey (NHANES I). Am J Clin Nutr 1994;59:110-4. PubMed
  6. Butland BK, Fehily AM, Elwood PC. Diet, lung function, and lung function decline in a cohort of 2512 middle aged men. Thorax 2000;55:102-8. PubMed
  7. Troisi RJ, Willett WC, Weiss ST, et al. A prospective study of diet and adult-onset asthma. Am J Respir Crit Care Med 1995;151:1401-8. PubMed
  8. Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103(3 Pt 1):507-13. PubMed
  9. Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7. PubMed
  10. Rance, F. and Dutau, G. Labial food challenge in children with food allergy. Pediatr Allergy Immunol. 1997;8(1):41-44. PubMed
  11. Kim, K. T. and Hussain, H. Prevalence of food allergy in 137 latex-allergic patients. Allergy Asthma Proc 1999;20(2):95-97. PubMed
  12. Ishida, T., Murai, K., Yasuda, T., Satou, T., Sejima, T., and Kitamura, K. [Oral allergy syndrome in patients with Japanese cedar pollinosis]. Nippon Jibiinkoka Gakkai Kaiho 2000;103(3):199-205. PubMed
  13. Lucas, J. S., Lewis, S. A., and Hourihane, J. O. Kiwi fruit allergy: a review. Pediatr.Allergy Immunol. 2003;14(6):420-428. PubMed
  14. Eriksson, N. E., Moller, C., Werner, S., Magnusson, J., Bengtsson, U., and Zolubas, M. Self-reported food hypersensitivity in Sweden, Denmark, Estonia, Lithuania, and Russia. J Investig.Allergol.Clin Immunol. 2004;14(1):70-79.
  15. Lucas, J. S., Grimshaw, K. E., Collins, K., Warner, J. O., and Hourihane, J. O. Kiwi fruit is a significant allergen and is associated with differing patterns of reactivity in children and adults. Clin.Exp.Allergy 2004;34(7):1115-1121. PubMed
  16. Hemmer, W., Focke, M., Gotz, M., and Jarisch, R. Sensitization to Ficus benjamina: relationship to natural rubber latex allergy and identification of foods implicated in the Ficus-fruit syndrome. Clin.Exp.Allergy 2004;34(8):1251-1258.
  17. Duttaroy, A. K. and Jorgensen, A. Effects of kiwi fruit consumption on platelet aggregation and plasma lipids in healthy human volunteers. Platelets. 2004;15(5):287-292. PubMed
  18. Chan, A. O., Leung, G., Tong, T., and Wong, N. Y. Increasing dietary fiber intake in terms of kiwifruit improves constipation in Chinese patients. World J Gastroenterol. 9-21-2007;13(35):4771-4775. PubMed
  19. Chang, C. C., Lin, Y. T., Lu, Y. T., Liu, Y. S., and Liu, J. F. Kiwifruit improves bowel function in patients with irritable bowel syndrome with constipation. Asia Pac.J Clin.Nutr. 2010;19(4):451-457.
  20. Brevik, A., Gaivao, I., Medin, T., Jorgenesen, A., Piasek, A., Elilasson, J., Karlsen, A., Blomhoff, R., Veggan, T., Duttaroy, A. K., and Collins, A. R. Supplementation of a western diet with golden kiwifruits (Actinidia chinensis var.'Hort 16A':) effect
  21. Veraldi, S. and Schianchi-Veraldi, R. Contact urticaria from kiwi fruit. Contact Dermatitis 1990;22(4):244. PubMed
  22. Garcia, B. E., de la Cuesta, C. G., Santos, F., Feliu, X., and Cordoba, H. A rare case of food allergy: monosensitivity to kiwi (Actinidia chinensis). Allergol.Immunopathol.(Madr.) 1989;17(4):217-218.
  23. Falliers, C. J. Anaphylaxis to Kiwi fruit and related "exoti"" items. J.Asthma 1983;20(3):193-196.
  24. Shimizu, T. and Morikawa, A. Anaphylaxis to kiwi fruit in a 12-year-old boy. J.Asthma 1995;32(2):159-160. PubMed
  25. Novembre, E., Bernardini, R., Bertini, G., Massai, G., and Vierucci, A. Skin-prick-test-induced anaphylaxis. Allergy 1995;50(6):511-513. PubMed
  26. Castillo, R., Delgado, J., Quiralte, J., Blanco, C., and Carrillo, T. Food hypersensitivity among adult patients: epidemiological and clinical aspects. Allergol.Immunopathol.(Madr.) 1996;24(3):93-97.
  27. Rademaker, M. Allergic contact dermatitis from kiwi fruit vine (actinidia chinensis). Contact Dermatitis 1996;34(3):221-222. PubMed
  28. Gastaminza, G., Bernaola, G., and Camino, M. E. Acute pancreatitis caused by allergy to kiwi fruit. Allergy 1998;53(11):1104-1105. PubMed
  29. Svendsen, M., Klemsdal, T. O., Heggen, E., Holme, I., Pedersen, T. R., Seljeflot, I., Blomhoff, R., and Tonstad, S. Effect of Dietary Intake of Kiwi Fruit on 24-Hour Ambulatory Blood Pressure (Abstract 16175). Circulation 2011;
  30. Eady SL, Wallace AJ, Hedderley DI, Bentley-Hewitt KL, Butts CA. The effects on immune function and digestive health of consuming the skin and flesh of Zespri SunGold Kiwifruit (Actinidia Chinensis var. Chinensis 'Zesy002') in healthy and IBS-constipated i
  31. Gabrielli S, Clarke AE, Morris J, et al. Fruit-induced anaphylaxis: clinical presentation and management. J Allergy Clin Immunol Pract 2021;9(7):2825-30. PubMed
  32. Ukleja-Sokolowska N, Zacniewski R, Lis K, Zbikowska-Gotz M, Kuzminski A, Bartuzi Z. Exercise induced anaphylaxis in kiwi allergic patient: case report. Allergy Asthma Clin Immunol 2021;17(1):91. PubMed

See these in context on the Kiwi monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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