Garcinia Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Garcinia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Garcinia is a dietary supplement by Premium Certified with 2 active ingredients. Its ingredients are commonly taken for weight loss, appetite suppression, curbing sugar and carb cravings.Based on those ingredients, 760 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Garcinia cambogia fruit rind extract, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Garcinia by Premium Certified
Ask about any prescription or over-the-counter medication and we check it for interactions with Garcinia by Premium Certified — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Garcinia by Premium Certified
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Premium Certified Garcinia contains 2 active ingredients: garcinia cambogia fruit rind extract and potassium. Garcinia extract is derived from the rind of the garcinia fruit and contains hydroxycitric acid (HCA), the compound believed to be responsible for its effects on appetite and metabolism.
Potassium is an electrolyte that plays a role in heart rhythm, muscle function, and blood pressure regulation. The capsule itself is made from vegetarian cellulose.
Does it work?
Couldn't assess
The evidence for garcinia's effectiveness is limited. Our data shows insufficient reliable evidence to rate it for athletic performance, fatty liver disease, high cholesterol, or weight management — meaning the studies we have access to don't yet support a clear conclusion about whether it works for these purposes.
No effectiveness ratings are available for potassium supplementation in this product's context, though potassium is an essential nutrient your body needs for proper heart and muscle function.
How safe is it?
Well-documented data
Garcinia is generally well tolerated in the short term, though rare reports of liver injury warrant caution. The most common side effects are diarrhea, stomach discomfort, headache, and nausea.
Rarely, garcinia has been linked to serious liver damage, mania, and in one case, severe heart muscle inflammation. Potassium from food is safe, but supplements can raise blood levels dangerously — especially in people with kidney disease — and may cause abdominal pain, nausea, diarrhea, or in rare cases, abnormal heartbeat or low blood pressure.
Do not use garcinia during pregnancy or while breastfeeding; there isn't enough safety data. For potassium specifically during pregnancy or breastfeeding, talk with your doctor or pharmacist before taking supplements.
Meds to double-check
Moderate interaction found
Before taking Premium Certified Garcinia, double-check with your doctor or pharmacist if you take any serotonergic drugs (antidepressants like escitalopram, sertraline, or others), potassium-sparing diuretics, ACE inhibitors, ARBs, anticoagulants or antiplatelet drugs, antidiabetes medications, or any drug that could stress your liver. High blood potassium is a serious risk with this product.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product combines garcinia, an ingredient with limited effectiveness evidence, and potassium, which carries real risks when mixed with certain medications or taken by people with kidney problems. If you take any blood pressure, heart, blood thinner, diabetes, or diuretic medication — or if you have kidney disease — check with your doctor or pharmacist before starting.
Even if you don't take medications, a conversation with your healthcare provider about whether you need potassium supplementation and whether garcinia is right for your goals is a good idea.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Garcinia, straight from the product label.
| Brand | Premium Certified |
|---|---|
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 27, 2021 |
| DSLD ID | 248609 |
| Product type | Botanical With Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Garcinia by Premium Certified, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Garcinia cambogia fruit rind extract | 1600 mg | -- |
| Potassium | 100 mg | -- |
Other ingredients: vegetarian Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take two capsules a day. For best results, take one in the morning and one in the afternoon.
Precautions
Warning: Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement.
Warning: Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement.
Keep out of the reach of children.
Do not use this product if outer seal around cap is missing or broken.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Storage
Store at room temperature.
General Statements
All Premium Certified products come with a 100% premium guarantee when purchased directly from Premium Certified. If you are not completely satisfied with your purchase, return the unused portion within 90 days for a full refund.
Seals/Symbols
Made In USA Not Tested On Animals
Formulation
Non GMO
Natural weight loss support Premium grade Highest standards
No GMOs No hormones No soy No preservatives No gluten No coloring
Vegan Friendly
Formula
Premium quality garcinia cambogia
With 95% HCA & potassium
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Garcinia by Premium Certified label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Garcinia by Premium Certified
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Garcinia cambogia fruit rind extract
Interacts with704 drugs
Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific eviden...
Garcinia cambogia fruit rind extract monograph & interactionsPotassium
Interacts with62 drugs
Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...
Potassium monograph & interactionsOther (inactive) ingredients: Vegetarian Cellulose. These complete the product’s ingredient list but are not active constituents.
Garcinia by Premium Certified Drug Interactions
HelloPharmacist Interaction Report
Premium Certified Garcinia combines garcinia cambogia fruit rind extract and potassium, and together they interact with a significant number of medications.
The most serious documented interaction involves garcinia and serotonergic drugs (antidepressants and similar medications) — a patient taking escitalopram experienced serotonin syndrome after adding garcinia. Both ingredients also raise concerns with blood pressure and heart medications: potassium can dangerously raise blood potassium levels when combined with ACE inhibitors, ARBs, or potassium-sparing diuretics, while garcinia may thin the blood when taken with anticoagulants or antiplatelet drugs.
Read the full breakdown — every affected drug type, severity by severity
Garcinia poses moderate-severity risks with blood sugar medications (theoretically increasing low blood sugar risk) and drugs that stress the liver. Potassium's main concern centers on kidney function and electrolyte balance — high blood potassium (hyperkalemia) can cause irregular heartbeat, low blood pressure, or heart block, especially in people with kidney disease or those already taking blood pressure medications that preserve potassium.
Altogether, these interactions span 761 individual medications.
Before you start this product, run your exact medications — especially any antidepressant, heart medication, blood thinner, blood pressure drug, diabetes medication, or diuretic — through the interaction checker on this page. If you have kidney disease or take any of those drug classes, talk with your doctor or pharmacist first.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Garcinia?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Garcinia interact with 760 drugs. Click any drug to see the details.
2 of the 2 ingredients in Garcinia interact with drugs. Each result below shows which ingredient is responsible. Garcinia cambogia fruit rind extract Potassium
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Fruit Rind Extract + Abciximab interactionAbiraterone
How Abiraterone interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Fruit Rind Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Read the full Garcinia Cambogia Fruit Rind Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Fruit Rind Extract + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Garcinia — through 1 ingredient. Tap an ingredient for the detail:
Garcinia Cambogia Fruit Rind ExtractSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia Fruit Rind Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Garcinia with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Garcinia cambogia fruit rind extract
Anticoagulant/Antiplatelet Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
HCA inhibits platelet aggregation in vitro. The inhibitory effect seems to be greater in platelets extracted from diabetic subjects than non-diabetic subjects.
Antidiabetes Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
HCA reduces fasting and postprandial blood glucose levels in animal models, theoretically by delaying glucose absorption. This effect has not been reported in humans.
Hepatotoxic Drugs
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
There have been reports of acute hepatitis with elevated liver enzymes associated with garcinia, when taken alone or in combination with other ingredients. Case reports collected from the Drug Induced Liver Injury Network suggest this risk may be greater in people who carry the HLA B*35:01 allele.
Serotonergic Drugs
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
In one report, a patient experienced serotonin syndrome after taking garcinia extract (60% hydroxycitric acid) 1000 mg daily in combination with escitalopram 20 mg, which had been taken for a year. The patient was switched to sertraline 50 mg daily and again experienced serotonin syndrome.
Potassium
Ace Inhibitors (Aceis)
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Angiotensin Receptor Blockers (Arbs)
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Potassium-Sparing Diuretics
Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.
Brand information
Manufacturer and brand details for Garcinia, from the product label.
Premium Certified
See all Premium Certified products- Name
- Premium Certified
- City
- Northbrook
- State
- IL
- ZipCode
- 60062
- Phone Number
- 888-893-1413
- Web Address
- www.premiumcertified.com
Garcinia by Premium Certified: Common Questions
Does Garcinia by Premium Certified interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is the garcinia extract in this supposed to do?
Why is there potassium in a garcinia weight-loss product?
What are the side effects I might feel?
Can I take this if I have kidney problems?
Is it safe to take this with my blood pressure medication?
Can I take this while pregnant or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Garcinia is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Garcinia’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Garcinia
Interacts with 704 drugsGarcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific evidence is weak and mixed, with most studies...
Read the full Garcinia monograph → Herb & supplement monographPotassium
Interacts with 62 drugsPotassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...
Read the full Potassium monograph →Sources & How We Checked
Garcinia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 56 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Garcinia 44 references
- Heymsfield SB, Allison DB, Vasselli JR, et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA 1998;280:1596-600. PubMed
- Soni MG, Burdock GA, Preuss HG, et al. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol 2004;42:1513-29. PubMed
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