Interactions on record — worth a quick check against your medications. Based on 6 of 7 ingredients. Check your meds →
Dietary supplement

KidneyAid Ingredients & Drug Interactions

by RidgeCrest Herbals

KidneyAid label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking KidneyAid against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

KidneyAid is a dietary supplement by RidgeCrest Herbals with 7 active ingredients. Its ingredients are commonly taken for kidney and bladder stones, urinary tract complaints, enlarged prostate symptoms.Based on those ingredients, 2,077 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Plantain, Fenugreek, Horsetail Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against KidneyAid by RidgeCrest Herbals

Ask about any prescription or over-the-counter medication and we check it for interactions with KidneyAid by RidgeCrest Herbals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of KidneyAid by RidgeCrest Herbals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 7 active ingredients.
  • “KidneyAid Herbal Blend” is a proprietary blend — the label gives one combined amount (1,200 mg) without saying how much of each component you get.

KidneyAid contains 7 active ingredients: hydrangea, horsetail extract, plantain, fenugreek, juniper, European goldenrod, and a KidneyAid herbal blend. The product also includes a trace mineral blend that we could not evaluate.

The remaining contents are vegetable capsule, microcrystalline cellulose, and silica — these are inactive ingredients used to form and fill the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support kidney function and promote urine flow.
  • We looked for evidence on: Kidney stones (nephrolithiasis), Urinary tract infections (UTIs), Benign prostatic hyperplasia (BPH), Urinary retention, Renal function, Electrolyte balance.
  • The closest evidence on file: Fenugreek is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Goldenrod is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH), Kidney stones (nephrolithiasis), Urinary tract infections (UTIs).
  • Also on file: Juniper is rated "Insufficient Reliable Evidence To Rate" for Kidney stones (nephrolithiasis), Urinary tract infections (UTIs).

The evidence for most of these ingredients is limited. Plantain, which is a type of psyllium, is effective for constipation and likely effective for heart health (coronary heart disease).

Fenugreek shows possibly effective evidence for sexual dysfunction, sexual arousal, period pain (dysmenorrhea), and diabetes. The others — hydrangea, horsetail, juniper, and goldenrod — do not have enough reliable evidence in our data to establish whether they work for their intended uses.

The evidence, ingredient by ingredient Hydrangea Horsetail Black Psyllium Fenugreek Juniper Goldenrod

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hydrangea and horsetail should be used cautiously and only short-term; human safety data are limited, and large or prolonged doses may cause unwanted effects. Hydrangea may cause stomach upset (gastroenteritis), dizziness, and chest tightness.

Horsetail may cause bloating, increased bowel movements, and nausea, and crude horsetail contains a compound called thiaminase that can deplete thiamine (vitamin B1) with prolonged use. Plantain is generally well tolerated with adequate fluids but can rarely cause bowel or esophageal blockage if taken with too little water.

Fenugreek is generally well tolerated but may cause abdominal pain, bloating, diarrhea, indigestion, gas, low blood sugar, and nausea; allergic reactions including severe ones (bronchospasm, throat swelling, shock) are rare. Juniper is generally tolerated short-term in low doses but may irritate the kidneys and should not be used long-term.

Goldenrod is often well tolerated short-term, but allergic skin reactions are possible. During pregnancy, avoid hydrangea, horsetail, juniper, and goldenrod — there is not enough safety data.

Fenugreek is likely unsafe in supplement amounts during pregnancy. Plantain is likely safe in pregnancy.

For breastfeeding, avoid hydrangea, horsetail, juniper, and goldenrod. Fenugreek is possibly safe while breastfeeding and is sometimes used to boost milk supply, though evidence is limited — discuss this with your provider.

There is no data on file for plantain during lactation.

Side effects, ingredient by ingredient Hydrangea Horsetail Black Psyllium Fenugreek Juniper Goldenrod

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Goldenrod, Black Psyllium, Hydrangea, Juniper, Fenugreek, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,078 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking KidneyAid, check with your doctor or pharmacist if you take HIV medications (antiretroviral drugs, especially efavirenz), blood sugar medications, blood thinners or antiplatelet drugs (warfarin, clopidogrel, aspirin), diuretics (water pills), lithium, heart medications (digoxin, metoprolol), seizure medications (phenytoin, carbamazepine), antipsychotics (olanzapine), asthma medication (theophylline), birth control pills, or erectile dysfunction drugs (sildenafil). These interactions range from Moderate to Minor severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

KidneyAid is a 7-ingredient herbal product with limited evidence of effectiveness for its intended uses and several important medication interactions — especially with blood sugar drugs, blood thinners, diuretics, lithium, and HIV medications. If you take any prescription medications, run them through the medication checker on this page before starting.

Anyone taking lithium, blood thinners, diabetes drugs, heart medications, or HIV medications should talk with their doctor or pharmacist before using this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about KidneyAid, straight from the product label.

Brand RidgeCrest Herbals
Barcode (UPC) 355724001681
Net contents 60 Vegan Capsule(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 302169
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for KidneyAid by RidgeCrest Herbals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
355724001681
IngredientAmount% DV
Hydrangea0 NP--
Horsetail Extract0 NP--
Plantain0 NP--
Fenugreek0 NP--
Juniper0 NP--
European Goldenrod0 NP--
KidneyAid Herbal Blend1200 mg--
Trace Mineral Blend150 mg--

Other ingredients: Vegetable capsule, Microcrystalline Cellulose, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Natural cleanse & support Support kidney function Maintain balanced electrolytes Promote urine flow

Eclectic Innovative Effective

Contains no animal products, nuts, corn, dairy, gluten, GMO, soy, wheat, or yeast.

Contains no animal products, nuts, corn, dairy, gluten, GMO, soy, wheat, or yeast.

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warnings: Do not use if safety seal around cap is broken or missing.

If pregnant or nursing, see a doctor before use.

Keep out of reach of children.

Guarantee valid through authorized resellers only.

Warning only required for sales in CA. For more info visit rcherbals.com/prop65. Warning: Consuming this product can expose you to chemicals including lead, which is known to the State of California to cause cancer and birth defects or reproductive harm. For more information go to www.p65warnings.ca.gov.

Suggested/Recommended/Usage/Directions

Directions: Adults and children age 12+, take 2 capsules daily between meals.

General Statements

Other information: Capsule size "00".

Please Recycle

Brand IP Statement(s)

"Guaranteed Results, Naturally!"

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

KidneyAid by RidgeCrest Herbals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

KidneyAid label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in KidneyAid by RidgeCrest Herbals

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

KidneyAid Herbal Blend

1200 mg per serving

Trace Mineral Blend

150 mg per serving

Other (inactive) ingredients: Vegetable capsule, Microcrystalline Cellulose, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

KidneyAid by RidgeCrest Herbals Drug Interactions

Want to check YOUR meds against KidneyAid?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,077Drugs
327 Moderate 1,750 Minor

Ingredients driving the most interactions

Plantain 2,025
Fenugreek 389
Horsetail Extract 188
Juniper 162
European Goldenrod 75

Individual Drug Interactions

The ingredients in KidneyAid interact with 2,077 drugs. Click any drug to see the details.

6 of the 7 ingredients in KidneyAid interact with drugs. Each result below shows which ingredient is responsible. Plantain Fenugreek Horsetail Extract Juniper European Goldenrod Hydrangea

Each ingredient & the kinds of drugs it affects

For each ingredient in KidneyAid with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Plantain7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Plantain full monograph & interactions

Fenugreek9 drug types · 389 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .

Likelihood Unlikely Evidence B
Antidiabetes Drugs

Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.

Likelihood Probable Evidence B
Clopidogrel (Plavix)

Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.

Likelihood Possible Evidence D
Metoprolol (Toprol)

Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Theophylline

Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.

Likelihood Possible Evidence D
Antihypertensive Drugs

Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.

Likelihood Possible Evidence C
Fenugreek full monograph & interactions

Horsetail Extract5 drug types · 188 drugs

Antidiabetes Drugs

Theoretically, taking horsetail with antidiabetes drugs might increase the risk of hypoglycemia.
Equisetum myriochaetum has demonstrated hypoglycemic activity in clinical research. In an animal diabetic model, Equisetum giganteum had hypoglycemic effects. It is unclear whether other horsetail species have hypoglycemic effects.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, taking horsetail with diuretic drugs might increase potassium loss and the risk of hypokalemia.
Laboratory research shows that various species of horsetail have diuretic properties. Due to its diuretic effects, there has been concern that taking horsetail along with potassium-depleting diuretics might increase the risk for hypokalemia. However, pharmacokinetic research in humans shows that taking horsetail 900 mg daily for 4 days does not affect urinary excretion of electrolytes, including potassium and sodium, despite having a diuretic effect similar to taking hydrochlorothiazide 25 mg daily. It is unclear if taking horsetail for a longer duration would affect electrolyte levels. Until more is known, use with caution.

Likelihood Possible Evidence D
Efavirenz (Sustiva)

Theoretically, horsetail might decrease the levels and clinical effects of efavirenz.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral regimen that included efavirenz. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing horsetail, the viral loads became undetectable in both cases. The exact mechanism of this interaction is unknown. It is also unclear if this interaction is specific to efavirenz or if it is related to various components of antiretroviral therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, horsetail might increase the levels and adverse effects of lithium.
Animal research suggests that horsetail has diuretic properties. Theoretically, due to these potential diuretic effects, horsetail might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Nucleoside Reverse Transcriptase Inhibitors (Nrtis)

Theoretically, horsetail might decrease the levels and clinical effects of NRTIs.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral therapy. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing the supplement, the viral loads became undetectable in both cases. The exact mechanism of these interactions is unknown. It is also unclear if these interactions are specific to NRTIs or if they are related to various components of antiretroviral therapy.

Likelihood Possible Evidence D
Horsetail Extract full monograph & interactions

Juniper3 drug types · 162 drugs

Antidiabetes Drugs

Theoretically, taking juniper berry with antidiabetes medications might cause additive hypoglycemia.
Animal research shows that juniper berry can lower blood glucose.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, juniper berry might increase the risk of adverse effects from diuretic drugs.
Juniper berry is thought to have mild diuretic effects.

Likelihood Possible Evidence D
Lithium

Theoretically, juniper berry might reduce lithium excretion and increase serum levels of lithium.
Juniper berry is thought to have mild diuretic effects.

Likelihood Possible Evidence D
Juniper full monograph & interactions

European Goldenrod1 drug type · 75 drugs

Diuretic Drugs

Theoretically, goldenrod might increase the effects and adverse effects of diuretic drugs.
In vitro and animal research suggests that goldenrod has diuretic effects.

Likelihood Possible Evidence D
European Goldenrod full monograph & interactions

Hydrangea1 drug type · 1 drug

Lithium

Hydrangea is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, hydrangea might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Hydrangea full monograph & interactions
The maker

Brand information

Manufacturer and brand details for KidneyAid, from the product label.

RidgeCrest Herbals

See all RidgeCrest Herbals products
Name
RidgeCrest Herbals
City
Salt Lake City
State
UT
ZipCode
84120
Phone Number
1-800-242-4649
Web Address
RCHerbals.com
Pharmacist Counseling Corner

KidneyAid by RidgeCrest Herbals: Common Questions

Does KidneyAid by RidgeCrest Herbals interact with any medications?
Yes. Based on its ingredients, KidneyAid has a known interaction with 2,077 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
KidneyAid contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take KidneyAid if I'm pregnant or breastfeeding?
Not all ingredients are safe in pregnancy or breastfeeding. Hydrangea, horsetail, juniper, and goldenrod should be avoided during pregnancy due to limited safety data. Fenugreek is likely unsafe in supplement amounts during pregnancy. Plantain is likely safe in pregnancy. For breastfeeding, there is not enough data for hydrangea, horsetail, juniper, and goldenrod, so they should be avoided. Fenugreek is possibly safe while breastfeeding. Talk with your doctor or pharmacist about your individual situation.
Can KidneyAid cause side effects?
Yes. Hydrangea may cause stomach upset, dizziness, and chest tightness. Horsetail may cause bloating, gas, and nausea. Plantain can cause bloating and gas. Fenugreek may cause abdominal pain, bloating, diarrhea, indigestion, gas, and nausea. Juniper and goldenrod are generally well tolerated but can cause allergic skin reactions in some people. Serious allergic reactions (throat swelling, trouble breathing, shock) are rare with fenugreek.
Does KidneyAid actually work?
Evidence is limited for most ingredients. Plantain (psyllium) is effective for constipation and likely effective for heart health. Fenugreek shows possibly effective evidence for sexual dysfunction, arousal, period pain, and diabetes. Hydrangea, horsetail, juniper, and goldenrod do not have enough reliable evidence in our data to establish whether they work for their intended uses.
What does horsetail do in this product?
Horsetail is traditionally used for kidney and urinary tract support, though we don't have reliable evidence it works. It's a diuretic (increases urine output). The concern is that it may interfere with blood sugar and blood thinner medications, and with lithium.
Why can't I take KidneyAid with diuretic pills?
Several ingredients in KidneyAid — hydrangea, horsetail, plantain, juniper, and goldenrod — all have diuretic effects. Taking them together with water pills may increase potassium loss and raise the risk of dangerously low potassium levels (hypokalemia).
What's the trace mineral blend, and why can't you check it?
The product contains a proprietary trace mineral blend, but we don't hold any interaction data for it, so we're unable to evaluate whether it interacts with medications. Ask the manufacturer or your pharmacist if you need specifics on what minerals it contains and in what amounts.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

KidneyAid label
Go deeper

The Full Monographs Behind KidneyAid’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hydrangea

Interacts with 1 drug

Hydrangea root has a long history in folk medicine, mainly for urinary and kidney stone complaints, but there is very little modern human research to confirm it works for any condition. Beca...

Read the full Hydrangea monograph → Herb & supplement monograph

Horsetail

Interacts with 188 drugs

Horsetail is a traditional herb most often used as a mild diuretic and for hair, nail, and bone support, but high-quality human evidence is limited. It can cause thiamine (vitamin B1) loss w...

Read the full Horsetail monograph → Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Fenugreek

Interacts with 389 drugs

Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. Some early research is encouraging for blo...

Read the full Fenugreek monograph → Herb & supplement monograph

Juniper

Interacts with 162 drugs

Juniper berry is a traditional herb best known for flavoring gin and for its folk use as a diuretic and digestive aid. Solid human evidence for its health benefits is limited, and it can irr...

Read the full Juniper monograph → Herb & supplement monograph

Goldenrod

Interacts with 75 drugs

Goldenrod is a flowering plant traditionally used as an herbal diuretic and for urinary tract health. Human evidence is limited, and while it is generally well tolerated, people with certain...

Read the full Goldenrod monograph →
Sources

Sources & How We Checked

KidneyAid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 76 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hydrangea 1 reference
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

See these in context on the Hydrangea monograph →

Horsetail 14 references
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See these in context on the Horsetail monograph →

Black Psyllium 18 references
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See these in context on the Black Psyllium monograph →

Fenugreek 30 references
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  14. Abdel-Barry, J. A., Abdel-Hassan, I. A., Jawad, A. M., and al Hakiem, M. H. Hypoglycaemic effect of aqueous extract of the leaves of Trigonella foenum-graecum in healthy volunteers. East Mediterr.Health J 2000;6(1):83-88. DOI
  15. Parvizpur, A., Ahmadiani, A., and Kamalinejad, M. Probable role of spinal purinoceptors in the analgesic effect of Trigonella foenum (TFG) leaves extract. J Ethnopharmacol 3-8-2006;104(1-2):108-112. PubMed
  16. Mora, A., Herrrera, A., Lopez, C., Dahbi, G., Mamani, R., Pita, J. M., Alonso, M. P., Llovo, J., Bernardez, M. I., Blanco, J. E., Blanco, M., and Blanco, J. Characteristics of the Shiga-toxin-producing enteroaggregative Escherichia coli O104:H4 German ou
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  20. Reeder C, Legrand A, O'Connor-Von SK. The Effect of Fenugreek on Milk Production and Prolactin Levels in Mothers of Preterm Infants. Clinical Lactation 2013;4(4):159-165. DOI
  21. Al-Jenoobi FI, Ahad A, Mahrous GM, Al-Mohizea AM, AlKharfy KM, Al-Suwayeh SA. Effects of fenugreek, garden cress, and black seed on theophylline pharmacokinetics in beagle dogs. Pharm Biol 2015;53(2):296-300. PubMed
  22. Rao A, Steels E, Inder WJ, Abraham S, Vitetta L. Testofen, a specialised Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males in a doubl
  23. Steels E, Rao A, Vitetta L. Physiological aspects of male libido enhanced by standardized Trigonella foenum-graecum extract and mineral formulation. Phytother Res. 2011 Sep;25(9):1294-300.
  24. Gong J, Fang K, Dong H, Wang D, Hu M, Lu F. Effect of fenugreek on hyperglycaemia and hyperlipidemia in diabetes and prediabetes: A meta-analysis. J Ethnopharmacol. 2016 Dec 24;194:260-268. PubMed
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See these in context on the Fenugreek monograph →

Juniper 7 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
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  4. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
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  7. Tammaro A, Adebanjo GAR, Chello C, et al. Bullous dermatitis caused by common juniper. Contact Dermatitis. 2020. PubMed

See these in context on the Juniper monograph →

Goldenrod 6 references
  1. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  2. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
  3. Chodera, A., Dabrowska, K., Sloderbach, A., Skrzypczak, L., and Budzianowski, J. [Effect of flavonoid fractions of Solidago virgaurea L on diuresis and levels of electrolytes]. Acta Pol.Pharm 1991;48(5-6):35-37.
  4. Chodera, A., Dabrowska, K., Bobkiewicz-Kozlowska, T., Tkaczyk, J., Skrzypczak, L., and Budzianowski, J. [Effect of leiocarposide on experimental urinary calculi in rats]. Acta Pol.Pharm 1988;45(2):181-186.
  5. Chodera, A., Dabrowska, K., Skrzypczak, L., and Budzianowski, J. [Further studies on the diuretic effect of leiocarposide]. Acta Pol.Pharm 1986;43(5):499-503.
  6. Chodera, A., Dabrowska, K., Senczuk, M., Wasik-Olejnik, A., Skrzypczak, L., Budzianowski, J., and Ellnain-Wojtaszek, M. [Diuretic effect of the glycoside from a plant of the Solidago L. genus]. Acta Pol.Pharm 1985;42(2):199-204.

See these in context on the Goldenrod monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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