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Dietary supplement

Saccharomyces 10B Ingredients & Drug Interactions

by Pure TheraPro Rx

Saccharomyces 10B label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Saccharomyces 10B against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Saccharomyces 10B is a dietary supplement by Pure TheraPro Rx with 1 active ingredient. Its ingredients are commonly taken for acute diarrhea, antibiotic-associated diarrhea, traveler's diarrhea.Based on those ingredients, 40 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Saccharomyces boulardii CNCM I-3799. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Saccharomyces 10B by Pure TheraPro Rx

Ask about any prescription or over-the-counter medication and we check it for interactions with Saccharomyces 10B by Pure TheraPro Rx — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Saccharomyces 10B by Pure TheraPro Rx

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

Saccharomyces 10B contains one active ingredient: Saccharomyces boulardii CNCM I-3799, a beneficial yeast strain used to support digestive health. The capsule also contains hypromellose, an inactive ingredient that helps deliver the probiotic.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: promote optimal gastrointestinal health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Travelers' diarrhea, Clostridioides difficile infection, Rotaviral diarrhea, HIV/AIDS-related diarrhea, Irritable bowel syndrome (IBS) — and 4 related terms.
  • The strongest evidence on file: Saccharomyces Boulardii is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Saccharomyces Boulardii is rated "Possibly Effective" for Rotaviral diarrhea, Travelers' diarrhea, Clostridioides difficile infection.
  • Also on file: Saccharomyces Boulardii is rated "Insufficient Reliable Evidence To Rate" for HIV/AIDS-related diarrhea, Crohn disease, Ulcerative colitis.

The evidence for Saccharomyces boulardii shows it is possibly effective for several types of diarrhea: rotaviral diarrhea, travelers' diarrhea, and antibiotic-associated diarrhea. It is also possibly effective for preventing necrotizing enterocolitis (a serious intestinal condition in premature infants), reducing Clostridioides difficile infection (a severe gut infection), and supporting treatment of Helicobacter pylori (a stomach bacteria).

Because the evidence is 'possibly effective' rather than proven, results can vary from person to person.

The evidence, ingredient by ingredient Saccharomyces Boulardii

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Saccharomyces boulardii is generally well tolerated in healthy adults, but safety data is limited and it should not be used by people who are critically ill or immunocompromised — talk with your doctor before taking it in those situations. Rarely, oral use has caused fungemia (a yeast infection in the bloodstream), particularly in critically ill patients in the ICU, those with central lines, or those on broad-spectrum antibiotics.

Gastrointestinal side effects are uncommon but can include abdominal cramps, gas, nausea, vomiting, or decreased appetite. There is not enough data on use during pregnancy or breastfeeding — discuss it with your doctor or pharmacist first.

Side effects, ingredient by ingredient Saccharomyces Boulardii

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Saccharomyces Boulardii.
  • The most serious interaction on file is rated Minor.
  • For scale: 40 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Saccharomyces 10B, double-check any antifungal medications you're on — including prescription and over-the-counter antifungals for yeast, fungal, or mold infections. Antifungals may reduce how well this probiotic works by killing the live yeast it contains.

Your doctor or pharmacist can advise on spacing or adjusting your routine.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Saccharomyces boulardii may help with several types of diarrhea if the evidence applies to your situation. It's generally well tolerated by healthy adults, but people who are critically ill, immunocompromised, or on central lines should avoid it and discuss with their doctor first.

If you take any antifungal medication, check with your pharmacist about timing before you start this probiotic.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Saccharomyces 10B, straight from the product label.

Brand Pure TheraPro Rx
Barcode (UPC) X001S7BZ6N
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 305965
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Saccharomyces 10B by Pure TheraPro Rx, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
X001S7BZ6N
IngredientAmount% DV
Saccharomyces boulardii CNCM I-37990 NP--

Other ingredients: Hypromellose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: take one (1) to two (2) capsules per day, or as directed by a healthcare practitioner.

Please note: for those unable to swallow capsules, open capsule and release the contents into water, juice or blend in apple sauce. Consume immediately after mixing. Do not heat.

Precautions

Warning: individuals taking medication, children and pregnant or lactating women should consult their healthcare practitioner prior to use. If taking anti-fungal(s), consume at least 2 hours prior or after.

Warning: individuals taking medication, children and pregnant or lactating women should consult their healthcare practitioner prior to use.

Do not use if you have severe immune suppression condition. Do not use if tamper seal is damaged.

Safe for children and pets. Storage: keep tightly closed in a cool, dry place out of reach of children.

Formula

Saccharomyces 10B delivers a minimum 10 billion CFUs (colony forming units) of Saccharomyces boulardii per daily serving to promote optimal gastrointestinal health. CNCM I-3799, our unique strain, survives stomach acid to protect the beneficial organisms of the intestine. Additionally, it supports the microflora, thereby promoting healthy immunity, digestion & gut health.

Formulation

Strain-verified through genetic typing to ensure maximum efficacy.

Formulated to exclude: fillers, gluten, wheat, soy, corn, animal or dairy products, shellfish, fish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMO's), artificial preservatives, sweeteners or colors.

Patented strain for optimal digestion & gut health

Formulated, tested & packaged in the USA

Vegan

Storage

Room temperature stable; no refrigeration necessary. Storage: keep tightly closed in a cool, dry place out of reach of children. Does not require refrigeration. Full potency guaranteed until expiration date when stored under proper storage conditions.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Good Manufacturing Practice GMP Certified

FDA Statement of Identity

Professional Dietary Supplement

Brand IP Statement(s)

Lynside Lynside is a trademark of Lesaffre et Compagnie, S.A. Copyright 2022 Pure TheraPro RX

Pure TheraPro RX Purity is priority

General Statements

Please recycle

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Saccharomyces 10B by Pure TheraPro Rx label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Saccharomyces 10B label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Saccharomyces 10B by Pure TheraPro Rx

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Saccharomyces boulardii CNCM I-3799

Interacts with
40 drugs
0 NP per serving Form: probiotic Yeast

Saccharomyces boulardii is a beneficial yeast used as a probiotic, with the strongest evidence for preventing and treating certain types of diarrhea,...

Saccharomyces boulardii CNCM I-3799 monograph & interactions

Other (inactive) ingredients: Hypromellose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Saccharomyces 10B by Pure TheraPro Rx Drug Interactions

Want to check YOUR meds against Saccharomyces 10B?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
40Drugs
40 Minor

Ingredients driving the most interactions

Saccharomyces boulardii CNCM I-3799 40

Individual Drug Interactions

The ingredients in Saccharomyces 10B interact with 40 drugs. Click any drug to see the details.

1 of the 1 ingredient in Saccharomyces 10B interact with drugs. Each result below shows which ingredient is responsible. Saccharomyces boulardii CNCM I-3799

Each ingredient & the kinds of drugs it affects

For each ingredient in Saccharomyces 10B with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Saccharomyces boulardii CNCM I-37991 drug type · 40 drugs

Antifungals

Theoretically, taking antifungals with Saccharomyces boulardii might decrease the effectiveness of Saccharomyces boulardii.
S. boulardii is a live yeast. Therefore, simultaneously taking antifungals might kill a significant number of the organisms.

Likelihood Possible Evidence D
Saccharomyces boulardii CNCM I-3799 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Saccharomyces 10B, from the product label.

Pure TheraPro Rx

See all Pure TheraPro Rx products
Name
Pure TheraPro Rx
Street Address
8781 Sheridan Blvd #6080
City
Westminster
State
CO
ZipCode
80003
Phone Number
888-655-4648
Web Address
Purethera.com
Pharmacist Counseling Corner

Saccharomyces 10B by Pure TheraPro Rx: Common Questions

Does Saccharomyces 10B by Pure TheraPro Rx interact with any medications?
Yes. Based on its ingredients, Saccharomyces 10B has a known interaction with 40 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Saccharomyces 10B contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Saccharomyces boulardii and how does it work?
Saccharomyces boulardii is a beneficial yeast strain that supports digestive health. It's been studied for its role in managing various types of diarrhea and certain gut infections.
Can I take this if I'm on antibiotics?
Saccharomyces boulardii is often used alongside antibiotics to help prevent antibiotic-associated diarrhea. However, if you're critically ill or on broad-spectrum antibiotics in an ICU setting, talk with your doctor first — there's a rare risk of fungemia in those situations.
What are the side effects?
Most people tolerate it well. Rarely, it can cause gas, abdominal cramps, nausea, vomiting, or decreased appetite. In very rare cases, particularly in critically ill patients, it can cause a bloodstream yeast infection — which is why it's not recommended for immunocompromised or critically ill people.
Is it safe during pregnancy or breastfeeding?
There isn't enough data to know whether Saccharomyces boulardii is safe in pregnancy or while breastfeeding. Talk with your doctor or pharmacist before taking it if you're pregnant or nursing.
Does it work for traveler's diarrhea?
Evidence suggests Saccharomyces boulardii is possibly effective for traveler's diarrhea, but results vary from person to person. It's not a guaranteed cure — think of it as one tool among others.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Saccharomyces 10B is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Saccharomyces 10B label
Go deeper

The Full Monographs Behind Saccharomyces 10B’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Saccharomyces Boulardii

Interacts with 40 drugs

Saccharomyces boulardii is a beneficial yeast used as a probiotic, with the strongest evidence for preventing and treating certain types of diarrhea, including antibiotic-associated diarrhea...

Read the full Saccharomyces Boulardii monograph →
Sources

Sources & How We Checked

Saccharomyces 10B's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Saccharomyces Boulardii 26 references
  1. Niault M, Thomas F, Prost J, et al. Fungemia due to Saccharomyces species in a patient treated with enteral Saccharomyces boulardii. Clin Infect Dis 1999;28:930.
  2. Pletinex M, Legein J, Vandenplas Y. Fungemia with Saccharomyces boulardii in a 1-year-old girl with protracted diarrhea. J Pediatr Gastroenterol Nutr 1995;21:113-5. DOI
  3. Fredenucci I, Chomarat M, Boucaud C, et al. Saccharomyces boulardii fungemia in a patient receiving ultra-levure therapy. Clin Infect Dis 1998;27:222-3.
  4. Elmer GW, McFarland LV, Surawicz CM, et al. Behaviour of Saccharomyces boulardii in recurrent Clostridium difficile disease patients. Aliment Pharmacol Ther 1999;13:1663-8.
  5. Lewis SJ, Freedman AR. Review article: the use of biotherapeutic agents in the prevention and treatment of gastrointestinal disease. Aliment Pharmacol Ther 1998;12:807-22. PubMed
  6. Cesaro S, Chinello P, Rossi L, Zanesco L. Saccharomyces cerevisiae fungemia in a neutropenic patient treated with Saccharomyces boulardii. Support Care Cancer 2000;8:504-5. PubMed
  7. Hennequin C, Thierry A, Richard GF, et al. Microsatellite typing as a new tool for identification of Saccharomyces cerevisiae strains. J Clin Microbiol 2001;39:551-9.
  8. Plein K, Hotz J. Therapeutic effects of Saccharomyces boulardii on mild residual symptoms in a stable phase of Crohn's disease with special respect to chronic diarrhea - a pilot study. Z Gastroenterol 1993;31:129-34.
  9. Borriello SP, Hammes WP, Holzapfel W, et al. Safety of probiotics that contain lactobacilli or bifidobacteria. Clin Infect Dis 2003;36:775-80. PubMed
  10. Marteau P, Seksik P. Tolerance of probiotics and prebiotics. J Clin Gastroenterol 2004;38:S67-9. PubMed
  11. Munoz P, Bouza E, Cuenca-Estrella M, et al. Saccharomyces cerevisiae fungemia: an emerging infectious disease. Clin Infect Dis 2005;40:1625-34. PubMed
  12. Lherm, T., Monet, C., Nougiere, B., Soulier, M., Larbi, D., Le Gall, C., Caen, D., and Malbrunot, C. Seven cases of fungemia with Saccharomyces boulardii in critically ill patients. Intensive Care Med 2002;28(6):797-801. PubMed
  13. Riquelme, A. J., Calvo, M. A., Guzman, A. M., Depix, M. S., Garcia, P., Perez, C., Arrese, M., and Labarca, J. A. Saccharomyces cerevisiae fungemia after Saccharomyces boulardii treatment in immunocompromised patients. J Clin.Gastroenterol. 2003;36(1):41- PubMed
  14. Cherifi, S., Robberecht, J., and Miendje, Y. Saccharomyces cerevisiae fungemia in an elderly patient with Clostridium difficile colitis. Acta Clin Belg. 2004;59(4):223-224. PubMed
  15. Ellouze O, Berthoud V, Mervant M, Parthiot JP, Girard C. Septic shock due to Sacccaromyces boulardii. Med Mal Infect. 2016;46(2):104-105.
  16. Appel-da-Silva MC, Narvaez GA, Perez LRR, Drehmer L, Lewgoy J. Saccharomyces cerevisiae var. boulardii fungemia following probiotic treatment. Med Mycol Case Rep. 2017;18:15-7. PubMed
  17. Atici S, Soysal A, Karadeniz Cerit K, et al. Catheter-related Saccharomyces cerevisiae Fungemia Following Saccharomyces boulardii Probiotic Treatment: In a child in intensive care unit and review of the literature. Med Mycol Case Rep. 2017;15:33-35. PubMed
  18. Martin IW, Tonner R, Trivedi J, et al. Saccharomyces boulardii probiotic-associated fungemia: questioning the safety of this preventive probiotic's use. Diagn Microbiol Infect Dis. 2017;87(3):286-8. PubMed
  19. Romanio MR, Coraine LA, Maielo VP, Abramczyc ML, Souza RL, Oliveira NF. Saccharomyces cerevisiae fungemia in a pediatric patient after treatment with probiotics. Rev Paul Pediatr 2017;35(3):361-4.
  20. Roy U, Jessani LG, Rudramurthy SM, et al. Seven cases of Saccharomyces fungaemia related to use of probiotics. Mycoses 2017;60(6):375-380.
  21. Romanio MR, Coraine LA, Maielo VP, Abramczyc ML, Souza RL, Oliveira NF. Saccharomyces cerevisiae fungemia in a pediatric patient after treatment with probiotics. Rev Paul Pediatr. 2017 Jul-Sep;35(3):361-364. doi: 10.1590/1984-0462/;2017;35;3;00014.
  22. Flatley EA, Wilde AM, Nailor MD. Saccharomyces boulardii for the prevention of hospital onset Clostridium difficile infection. J Gastrointestin Liver Dis. 2015;24(1):21-4. PubMed
  23. Ventoulis I, Sarmourli T, Amoiridou P, et al. Bloodstream infection by Saccharomyces cerevisiae in two COVID-19 patients after receiving supplementation of Saccharomyces in the ICU. J Fungi (Basel). 2020;6(3):98. PubMed
  24. Wombwell E, Bransteitter B, Gillen LR. Incidence of Saccharomyces cerevisiae fungemia in hospitalised patients administered Saccharomyces boulardii probiotic. Mycoses 2021;64(12):1521-1526.
  25. Rannikko J, Holmberg V, Karppelin M, et al. Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements. Emerg Infect Dis 2021;27(8):2090-6.
  26. Awoyemi A, Mayerhofer C, Felix AS, et al. Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial. EBioMedicine 2021;70:103511. PubMed

See these in context on the Saccharomyces Boulardii monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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