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Dietary supplement

Sheep Sorrel Ingredients & Drug Interactions

by Hawaii Pharm

Sheep Sorrel label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sheep Sorrel against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Sheep Sorrel is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for sinus and respiratory congestion, digestive upset, fever.Based on those ingredients, 169 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Sheep Sorrel extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Sheep Sorrel by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Sheep Sorrel by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Sheep Sorrel by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: certified organic sorrel extract. Sorrel is a plant used in traditional herbal medicine, and this liquid form also includes vegetable palm glycerin and pharmaceutical-grade alcohol as inactive ingredients to deliver and preserve the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Sorrel product and its label doesn't state a use — see Sorrel's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence supporting sorrel for bronchitis, breast cancer, and rhinosinusitis (sinus inflammation) is insufficient to rate it as effective. We don't hold enough reliable research data to say whether it works for these conditions or not.

The evidence, ingredient by ingredient Sorrel

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sorrel is generally well tolerated when used in the amounts you'd eat as a food. The main safety concern is its high oxalate content — in large or concentrated medicinal doses, oxalates can accumulate in your system and potentially damage your kidneys.

A case of kidney inflammation was reported in a child who consumed wild sorrel, though recovery happened after supportive care. Some people allergic to weed pollen may also react to sorrel pollen.

When sorrel has been combined with other herbs in studies, gastrointestinal side effects like nausea and an unpleasant aftertaste have been reported. Safety data for medicinal use is limited, so concentrated supplements are best avoided while breastfeeding.

Side effects, ingredient by ingredient Sorrel

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sorrel.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 169 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you take blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel), allergy medications like fexofenadine, or any drug transported by OATP carriers. The sorrel extract may reduce how well these work or increase bleeding risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're on blood thinners or take allergy medications like fexofenadine, talk with your pharmacist before starting this product — the interactions are documented but uncommon in real life. Also be aware that large doses could stress your kidneys due to oxalate buildup.

This is a liquid extract, not a food amount, so safety in medicinal doses is less certain than eating sorrel as a leafy green.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sheep Sorrel, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 650905467905
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Nov 21, 2020
DSLD ID 237622
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sheep Sorrel by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
650905467905
IngredientAmount% DV
certified organic Sheep Sorrel extract970 mg--

Other ingredients: Vegetable Palm Glycerin, pharmaceutical grade Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no GMO, gluten, artificial colors, heavy metals, preservatives, pesticides, fertilizers.

Super concentrated liquid herbal extract. Dry herb/menstruum ratio: 1:3.

Manufactured in an FDA registered facility.

Non GMO Gluten free

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops (0.7-1 ml, one full squeeze of the dropper bulb) to 2-4 oz of juice or water up to 4 times per day.

Precautions

Warning: Keep out of the reach of children.

May have contraindications. We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing or taking any medications.

Do not use if seal is broken or missing.

Storage

Store in a cool dry place.

Formula

(Rumex acetosella)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sheep Sorrel by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sheep Sorrel label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sheep Sorrel by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Certified organic Sheep Sorrel extract

Interacts with
169 drugs
970 mg per serving

Sorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation. Solid human evidence for an...

Certified organic Sheep Sorrel extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Pharmaceutical grade Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sheep Sorrel by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Sheep Sorrel?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
169Drugs
169 Moderate

Ingredients driving the most interactions

certified organic Sheep Sorrel extract 169

Individual Drug Interactions

The ingredients in Sheep Sorrel interact with 169 drugs. Click any drug to see the details.

1 of the 1 ingredient in Sheep Sorrel interact with drugs. Each result below shows which ingredient is responsible. certified organic Sheep Sorrel extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Sheep Sorrel with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Sheep Sorrel extract3 drug types · 169 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
In vitro, sorrel has been shown to inhibit platelet aggregation. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Fexofenadine (Allegra)

Sorrel might reduce the effectiveness of fexofenadine by reducing its absorption from the gut.
In vitro research shows that an ethanol extract of sorrel inhibits organic anion-transporting polypeptide 1A2 (OATP1A2), which transports fexofenadine from the intestine into cells. In rats, concomitant administration of sorrel extract with fexofenadine reduces oral absorption of fexofenadine and the area under the plasma concentration-time curve (AUC).

Likelihood Likely Evidence D
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Sorrel might reduce the effectiveness of OATP substrates by reducing their absorption from the gut.
In vitro research shows that sorrel inhibits OATP1A2. Theoretically it may inhibit other OATPs. The OATPs are expressed in the small intestine and liver and transport drugs into cells. Inhibition of OATP may reduce the bioavailability of oral drugs that are substrates of OATP.

Likelihood Possible Evidence D
certified organic Sheep Sorrel extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sheep Sorrel, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Sheep Sorrel by Hawaii Pharm: Common Questions

Does Sheep Sorrel by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Sheep Sorrel has a known interaction with 169 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sheep Sorrel contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does sorrel cause kidney problems?
Sorrel is high in oxalates, which can accumulate when you take large or concentrated doses. While food amounts are fine, medicinal extracts like this one might raise your risk of kidney issues in sensitive people or with long-term use. One case of kidney inflammation was reported in a child; they recovered after treatment. If you have kidney disease or a history of kidney stones, talk to your pharmacist first.
Will this help my bronchitis?
We don't have enough reliable research to say whether sorrel works for bronchitis. The evidence is insufficient to rate it as effective.
Can I take this while breastfeeding?
There isn't enough safety data for medicinal amounts of sorrel while breastfeeding. Because this is a concentrated extract — not food — it's best to avoid it and talk with your doctor or pharmacist for personalized advice.
Is sorrel safe during pregnancy?
The available data rates sorrel as possibly safe during pregnancy, but the evidence is limited. For a medicinal extract like this, it's smart to discuss it with your doctor or pharmacist first to make sure it's right for your situation.
What are the side effects?
Most people tolerate sorrel food amounts well. With medicinal use, some people have reported nausea and an unpleasant aftertaste when sorrel was combined with other herbs. If you're allergic to weed pollen, you might react to sorrel pollen as well.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sheep Sorrel is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sheep Sorrel label
Go deeper

The Full Monographs Behind Sheep Sorrel’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sorrel

Interacts with 169 drugs

Sorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation. Solid human evidence for any health benefit is limited, and its hig...

Read the full Sorrel monograph →
Sources

Sources & How We Checked

Sheep Sorrel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sorrel 8 references
  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Zick, S. M., Sen, A., Feng, Y., Green, J., Olatunde, S., and Boon, H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med 2006;12(10):971-980. PubMed
  4. Sanz, P. and Reig, R. Clinical and pathological findings in fatal plant oxalosis. A review. Am J Forensic Med Pathol. 1992;13(4):342-345. PubMed
  5. Gniazdowska, B., Doroszewska, G., and Doroszewski, W. [Hypersensitivity to weed pollen allergens in the region of Bygdoszcz]. Pneumonol.Alergol.Pol. 1993;61(7-8):367-372.
  6. Selçuk SN, Gülhan B, Düzova A, Teksam Ö. Acute tubulointerstitial nephritis due to large amount of sorrel (Rumex acetosa) intake. Clin Toxicol (Phila) 2015;53(5):497. PubMed
  7. Ahn JH, Kim J, Rehman NU, Kim HJ, Ahn MJ, Chung HJ. Effect of Rumex Acetosa Extract, a Herbal Drug, on the Absorption of Fexofenadine. Pharmaceutics. 2020;12(6):E547. PubMed
  8. Jeong D, Irfan M, Lee DH, Hong SB, Oh JW, Rhee MH. Rumex acetosa modulates platelet function and inhibits thrombus formation in rats. BMC Complement Med Ther. 2020;20(1):98. PubMed

See these in context on the Sorrel monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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