Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Solid 550 mg Ingredients & Drug Interactions

by BPI Sports

Solid 550 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Solid 550 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Solid 550 mg is a dietary supplement by BPI Sports with 4 active ingredients. Its ingredients are commonly taken for cold sores and herpes lesions (topical), sore throat and mouth sores, wound and skin healing.Based on those ingredients, 1,127 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Propolis, Andrographis paniculata extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Solid 550 mg by BPI Sports

Ask about any prescription or over-the-counter medication and we check it for interactions with Solid 550 mg by BPI Sports — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Solid 550 mg by BPI Sports

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 4 active ingredients. Propolis is a bee-derived resin used traditionally for immune and oral health support.

Andrographis paniculata extract comes from an herb also called the "king of bitters," traditionally used for inflammatory conditions. Palmyra palm extract and Paris polyphylla extract round out the formula, though we hold limited data on the latter two.

The capsule itself is made from gelatin and filled with inactive ingredients including microcrystalline cellulose, dicalcium phosphate, magnesium stearate, silica, and several FD&C colorants.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: anabolic and androgenic support for lean muscle.
  • We looked for evidence on: Athletic performance, Muscle fatigue, muscle strength, muscle definition, muscle growth.
  • The closest evidence on file: Propolis is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Propolis is rated "Insufficient Reliable Evidence To Rate" for Muscle fatigue.

Propolis is possibly effective for oral mucositis (mouth inflammation from cancer treatment) and cold sores (herpes labialis). It may also help with blood sugar control in diabetes, though the evidence is limited.

For dengue fever, the evidence is insufficient to rate it. Andrographis paniculata extract is possibly effective for ulcerative colitis, sore throat (tonsillopharyngitis), and osteoarthritis.

Like propolis, it's not rated for familial Mediterranean fever due to insufficient evidence. The evidence for both ingredients on their respective uses is "possibly effective" — meaning there's some supporting data, but it's not definitive.

The evidence, ingredient by ingredient Propolis Andrographis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Propolis is generally well tolerated when taken short-term, though allergic reactions are possible—especially if you're sensitive to bee products. The most common side effect is mild headache; in one trial, about 7% of people taking 250 mg twice daily for 4 months reported it.

Topically, it can cause contact dermatitis or allergic reactions on the skin. Andrographis is also generally well tolerated short-term but can cause headache, fatigue, diarrhea, nausea, rash, or dizziness—particularly at higher doses or beyond 14 days of use.

Serious allergic reactions, including anaphylaxis, are rare but possible with either ingredient. Propolis should be avoided during pregnancy and breastfeeding due to insufficient safety data.

Andrographis is possibly unsafe in pregnancy (avoid it) and should be avoided while breastfeeding. We hold no pregnancy or breastfeeding safety data for Palmyra palm or Paris polyphylla extract.

Side effects, ingredient by ingredient Propolis Andrographis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Propolis, Andrographis.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 1,128 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking BPI Sports Solid 550 mg, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (including aspirin and warfarin)—propolis and andrographis may increase bleeding risk or reduce warfarin's effect. Also confirm use if you're on blood pressure medications (andrographis may lower it further), immunosuppressants (andrographis may interfere), or any drug metabolized by your liver's CYP enzymes (propolis may raise its levels).

Pain relievers and diabetes medications should also be reviewed.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is a four-ingredient immune and inflammation supplement that may help with mouth sores, sore throat, or arthritis symptoms—though the evidence is moderate. If you take any blood thinners, blood pressure medications, immunosuppressants, or drugs metabolized by your liver, you need to clear this with your doctor or pharmacist before starting.

People allergic to bee products should avoid it. Talk with your healthcare provider about whether this fits your personal health situation before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Solid 550 mg, straight from the product label.

Brand BPI Sports
Barcode (UPC) 811213022525
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Nov 20, 2017
DSLD ID 80117
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Solid 550 mg by BPI Sports, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
811213022525
IngredientAmount% DV
Propolis50 mg--
Andrographis paniculata extract400 mg--
Palmyra palm (Borassus aethiopum) extract50 mg--
Paris polyphylla extract50 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Dicalcium Phosphate, Magnesium Stearate, Silica, Titanium Dioxide, FD&C Blue No. 1, FD&C Red No. 40, FD&C Yellow No. 6, FD&C Green No. 3, FD&C Red No. 3

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

May Experience: Lean muscle definition Increased strength Increased performance

Stronger formula

Cutting & hardening agent

May Experience: Anabolic & androgenic support Lean muscle definition Muscle fullness

Maximum potency

Anabolic and Androgenic refer to male hormones responsible for lean muscle growth, increased strength, performance and body composition.

To report an adverse event or for more information call: 954.926.0900 (tel)

Facebook www.facebook.com/BPIonline

References select isolated constituent parts, as it relates to analytical characterization of the same.

When combined with a proper exercise and nutrition regimen. Statements based on early-stage independent 3rd party in vivo and/or in vitro model scientific research data findings for individual ingredients.

Seals/Symbols

Independent Laboratory Certified Third-Party

Brand IP Statement(s)

Be Better. Be Stronger. BPI.

Solid is an advanced anabolic and androgenic support agent. This powerful formula may help you experience increased definition, and muscle fullness.

Suggested/Recommended/Usage/Directions

4 week cycle

Stacking protocol Solid x1 in the morning (same time each day) 4 week cycle

Please read entire label before use.

Suggested Use: Take one (1) capsule daily, (in the morning) at the same time each day, or as directed by a qualified healthcare practitioner. Must be taken on a full stomach. For best results, take four to eight (4-8) consecutive weeks (1-2 Cycles). A four (4) week break between cycles is recommended.

FDA Statement of Identity

Dietary Supplement

Precautions

Warnings: Not intended for use by persons under age 18.

Do not exceed recommended dose. Do not take for more than eight (8) consecutive weeks.

Get the consent of a licensed physician before using this product, especially if you are taking medication or have a medical condition.

This product should not be taken by women.

Do not take if you are pregnant, lactating or trying to become pregnant.

Keep this product and all supplements out of the reach of children.

General

Rev. 01-005-AES001 01/17

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Solid 550 mg by BPI Sports label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Solid 550 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Solid 550 mg by BPI Sports

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Propolis

Interacts with
921 drugs
50 mg per serving

Propolis is a natural, resin-like substance made by bees that has antimicrobial and anti-inflammatory properties in lab studies. Early research sugges...

Propolis monograph & interactions

Andrographis paniculata extract

Interacts with
413 drugs
400 mg per serving Form: Andrographolide

Andrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms and shorten...

Andrographis paniculata extract monograph & interactions

Palmyra palm (Borassus aethiopum) extract

50 mg per serving

Paris polyphylla extract

50 mg per serving

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Dicalcium Phosphate, Magnesium Stearate, Silica, Titanium Dioxide, FD&C Blue No. 1, FD&C Red No. 40, FD&C Yellow No. 6, FD&C Green No. 3, FD&C Red No. 3. These complete the product’s ingredient list but are not active constituents.

Interaction report

Solid 550 mg by BPI Sports Drug Interactions

Want to check YOUR meds against Solid 550 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,127Drugs
1,127 Moderate

Ingredients driving the most interactions

Propolis 921
Andrographis paniculata extract 413

Individual Drug Interactions

The ingredients in Solid 550 mg interact with 1,127 drugs. Click any drug to see the details.

2 of the 4 ingredients in Solid 550 mg interact with drugs. Each result below shows which ingredient is responsible. Propolis Andrographis paniculata extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Solid 550 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Propolis8 drug types · 921 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, propolis might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.
In vitro research shows that propolis water extract and the propolis constituent, caffeic acid phenethyl ester, can inhibit platelet aggregation. Additionally, evidence from an animal model shows that taking propolis in addition to warfarin decreases INR, suggesting that propolis can decrease the effectiveness of warfarin.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP1A2.
In vitro research shows that propolis extract can inhibit CYP1A2. However, animal research shows that propolis extract does not significantly affect CYP1A2 activity when administered to rats at doses up to 250 mg/kg. It is postulated that the constituents of propolis that inhibit CYP1A2 in vitro do not have significant effects in vivo due to low bioavailability and hepatic first-pass effect. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP2C19.
In vitro research shows that propolis extract can inhibit CYP2C19. However, animal research shows that propolis extract does not significantly affect CYP2C19 activity when administered to rats at doses up to 250 mg/kg. It is postulated that the constituents of propolis that inhibit CYP2C19 in vitro do not have significant effects in vivo due to low bioavailability and hepatic first-pass effect. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP2C9.
In vitro research shows that propolis extract can inhibit CYP2C9. However, animal research shows that propolis extract does not significantly affect CYP2C9 activity when administered to rats at doses up to 250 mg/kg. It is postulated that the constituents of propolis that inhibit CYP2C9 in vitro do not have significant effects in vivo due to low bioavailability and hepatic first-pass effect. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP2D6.
In vitro research shows that propolis extract can inhibit CYP2D6. However, animal research shows that propolis extract does not significantly affect CYP2D6 activity when administered to rats at doses up to 250 mg/kg. It is postulated that the constituents of propolis that inhibit CYP2D6 in vitro do not have significant effects in vivo due to low bioavailability and hepatic first-pass effect. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, propolis might increase levels of drugs metabolized by CYP2E1.
In vitro research shows that propolis can inhibit CYP2E1. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, high doses of propolis might increase blood levels of drugs metabolized by CYP3A4.
Some in vitro research shows that propolis extract can inhibit CYP3A4; however, other in vitro research shows that propolis has no effect on CYP3A4 activity. Furthermore, animal research shows that propolis extract does not significantly affect CYP3A4 activity when administered to rats at doses up to 250 mg/kg. It is postulated that the constituents of propolis that might in inhibit CYP3A4 in vitro do not have significant effects in vivo due to low bioavailability and hepatic first-pass effect. This effect has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, propolis might decrease the effectiveness of warfarin.
Animal research shows that taking propolis in addition to warfarin decreases the international normalized ratio (INR). This effect has not been reported in humans.

Likelihood Possible Evidence D
Propolis full monograph & interactions

Andrographis paniculata extract6 drug types · 413 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal and laboratory studies suggest that andrographis has antiplatelet effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Animal research suggests that andrographis has hypotensive effects.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Laboratory research suggests that andrographolide has immunostimulant activity.

Likelihood Possible Evidence D
Celecoxib (Celebrex)

Theoretically, andrographis extract might increase the maximum concentration and time to peak concentration of celecoxib. The clinical significance of these changes is unclear.
Animal research suggests that andrographis extract taken orally increases the maximum concentration and time to peak concentration of celecoxib but does not appear to impact the area under the curve.

Likelihood Possible Evidence D
Etoricoxib (Arcoxia)

Theoretically, andrographis might decrease the absorption of etoricoxib, although the clinical significance is unclear.
Animal research shows that andrographis extract, or the constituent andrographolide, taken orally with etoricoxib decreases the bioavailability of etoricoxib. However, this reduced bioavailability is not correlated with a reduction in the anti-inflammatory effects of etoricoxib in arthritic mice models. The clinical significance of this interaction is unclear.

Likelihood Possible Evidence D
Glipizide (Glucotrol)

Theoretically, andrographis extract might increase the maximum concentration and area under the curve of glipizide; however, opposite effects are seen with the constituent, andrographolide. The clinical significance of this interaction is unclear.
Animal research suggests that andrographis extract taken orally with glipizide in diabetes-induced rats increases the maximum concentration and area under the curve of glipizide. However, the opposite effect is seen with the constituent, andrographolide, in which the maximum concentration and area under the curve are decreased when taken with glipizide.

Likelihood Possible Evidence D
Andrographis paniculata extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Solid 550 mg, from the product label.

BPI Sports

See all BPI Sports products
Name
BPI Sports
Street Address
3149 SW 42nd St. Suite 200
City
Hollywood
State
FL
ZipCode
33312
Phone Number
954.926.0900
Web Address
www.bpisports.com
Pharmacist Counseling Corner

Solid 550 mg by BPI Sports: Common Questions

Does Solid 550 mg by BPI Sports interact with any medications?
Yes. Based on its ingredients, Solid 550 mg has a known interaction with 1,127 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Solid 550 mg contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe if I'm allergic to bees?
No—propolis is a bee-derived product, and allergic reactions are possible, especially if you're sensitive to bee products. If you have a bee allergy, avoid this supplement or talk with your doctor first.
Can I take this while pregnant or breastfeeding?
Not recommended. Propolis should be avoided during both pregnancy and breastfeeding due to insufficient safety data. Andrographis is possibly unsafe in pregnancy and should also be avoided while breastfeeding. Talk with your doctor or pharmacist about whether this is right for you if you're pregnant or nursing.
What's the most common side effect?
Headache is the most commonly reported side effect with propolis—about 7% of people in one trial experienced mild headache when taking 250 mg twice daily. Andrographis can also cause headache, along with fatigue, diarrhea, nausea, or rash, especially at higher doses or longer use.
Does this actually work for cold sores and mouth sores?
Propolis is possibly effective for cold sores and oral mucositis (mouth inflammation), meaning there's some supporting evidence but it's not conclusive. Andrographis is possibly effective for sore throat. The evidence for both is moderate, so results can vary.
How long can I safely take this?
Both propolis and andrographis are generally well tolerated short-term. Andrographis side effects are more likely when doses are high or use exceeds 14 days. We don't hold firm long-term safety data for either ingredient, so talk with your pharmacist or doctor about how long to use it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Solid 550 mg label
Go deeper

The Full Monographs Behind Solid 550 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Propolis

Interacts with 921 drugs

Propolis is a natural, resin-like substance made by bees that has antimicrobial and anti-inflammatory properties in lab studies. Early research suggests it may help with cold sores, mouth so...

Read the full Propolis monograph → Herb & supplement monograph

Andrographis

Interacts with 413 drugs

Andrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms and shorten how long they last. The evidence is limi...

Read the full Andrographis monograph →
Sources

Sources & How We Checked

Solid 550 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 47 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Propolis 21 references
  1. Hay KD, Greig DE. Propolis allergy: a cause of oral mucositis with ulceration. Oral Surg Oral Med Oral Pathol 1990;70:584-6. PubMed
  2. Li YJ, Lin JL, Yang CW, Yu CC. Acute renal failure induced by a Brazilian variety of propolis. Am J Kidney Dis 2005;46:e125-9. PubMed
  3. Jensen CD, Andersen KE. Allergic contact dermatitis from cera alba (purified propolis) in a lip balm and candy. Contact Dermatitis 2006;55:312-3. PubMed
  4. Chen, T. G., Lee, J. J., Lin, K. H., Shen, C. H., Chou, D. S., and Sheu, J. R. Antiplatelet activity of caffeic acid phenethyl ester is mediated through a cyclic GMP-dependent pathway in human platelets. Chin J Physiol 6-30-2007;50(3):121-126.
  5. Hsu, C. Y., Chiang, W. C., Weng, T. I., Chen, W. J., and Yuan, A. Laryngeal edema and anaphalactic shock after topical propolis use for acute pharyngitis. Am J Emerg.Med 2004;22(5):432-433. PubMed
  6. Black, R. J. Vulval eczema associated with propolis sensitization from topical therapies treated successfully with pimecrolimus cream. Clin Exp.Dermatol. 2005;30(1):91-92. PubMed
  7. Matos D, Serrano P, Brandao FM. A case of allergic contact dermatitis caused by propolis-enriched honey. Contact Dermatitis 2015;72(1):59-60. PubMed
  8. Naramoto K, Kato M, Ichihara K. Effects of an ethanol extract of Brazilian green propolis on human cytochrome P450 enzyme activities in vitro. J Agric Food Chem 2014;62(46):11296-302. PubMed
  9. Nyman G, Hagvall L. A case of allergic contact cheilitis caused by propolis and honey. Contact Dermatitis 2016;74(3):186-7. PubMed
  10. Ryu CS, Oh SJ, Oh JM, et al. Inhibition of cytochrome P450 by propolis in human liver microsomes. Toxicol Res 2016;32(3):207-13. PubMed
  11. Akbay E, Özenirler Ç, Çelemli ÖG, Durukan AB, Onur MA, Sorkun K. Effects of propolis on warfarin efficacy. Kardiochir Torakochirurgia Pol. 2017;14(1):43-46. PubMed
  12. Lamoureux A, Meharon M, Durand AL, Darrigade AS, Doutre MS, Milpied B. A first case of erythema multiforme-like contact dermatitis caused by propolis. Contact Dermatitis. 2017;77(4):263-264. PubMed
  13. Piredda M, Facchinetti G, Biagioli V, et al. Propolis in the prevention of oral mucositis in breast cancer patients receiving adjuvant chemotherapy: A pilot randomised controlled trial. Eur J Cancer Care (Engl). 2017;26(6). PubMed
  14. Zhang YX, Yang TT, Xia L, Zhang WF, Wang JF, Wu YP. Inhibitory Effect of Propolis on Platelet Aggregation In Vitro. J Healthc Eng. 2017;2017:3050895. PubMed
  15. Nyman GSA, Tang M, Inerot A, Osmancevic A, Malmberg P, Hagvall L. Contact allergy to beeswax and propolis among patients with cheilitis or facial dermatitis. Contact Dermatitis 2019;81(2):110-6. PubMed
  16. Igarashi G, Segawa T, Akiyama N, et al. Efficacy of Brazilian propolis supplementation for japanese lactating women for atopic sensitization and nonspecific symptoms in their offspring: a randomized, double-blind, placebo-controlled trial. Evid Based Comp PubMed
  17. Soleimani D, Rezaie M, Rajabzadeh F, et al. Protective effects of propolis on hepatic steatosis and fibrosis among patients with nonalcoholic fatty liver disease (NAFLD) evaluated by real-time two-dimensional shear wave elastography: a randomized clinical
  18. D'Ercole MC. Prolonged use of propolis can increase liver enzymes. J Gastrointestin Liver Dis 2020;29(3):468-9. PubMed
  19. Cho E, Lee JD, Cho SH. Systemic contact dermatitis from propolis ingestion. Ann Dermatol. 2011;23(1):85-88. PubMed
  20. Hallajzadeh J, Milajerdi A, Amirani E, Attari VE, Maghsoudi H, Mirhashemi SM. Effects of propolis supplementation on glycemic status, lipid profiles, inflammation and oxidative stress, liver enzymes, and body weight: a systematic review and meta-analysis
  21. Gheflati A, Dehnavi Z, Ghannadzadeh Yazdi A, Khorasanchi Z, Raeisi-Dehkordi H, Ranjbar G. The effects of propolis supplementation on metabolic parameters: a systematic review and meta-analysis of randomized controlled clinical trials. Avicenna J Phytomed

See these in context on the Propolis monograph →

Andrographis 26 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Thamlikitkul V, Dechatiwongse T, Theerapong S, et al. Efficacy of Andrographis paniculata, Nees for pharyngotonsillitis in adults. J Med Assoc Thai 1991;74:437-42.
  3. Zhang CY, Tan BK. Mechanisms of cardiovascular activity of Andrographis paniculata in the anaesthetized rat. J Ethnopharmacol 1997;56:97-101. PubMed
  4. Zhao HY, Fang WY. Antithrombotic effects of Andrographis paniculata nees in preventing myocardial infarction. Chin Med J (Engl) 1991;104:770-5.
  5. Amroyan E, Gabrielian E, Panossian A, et al. Inhibitory effect of andrographolide from Andrographis paniculata on PAF-induced platelet aggregation. Phytomedicine 1999;6:27-31. PubMed
  6. Zhang C, Kuroyangi M, Tan BK. Cardiovascular activity of 14-deoxy-11,12-didehydroandrographolide in the anaesthetised rat and isolated right atria. Pharmacol Res 1998;38:413-7. PubMed
  7. Puri A, Saxena R, Saxena RP, et al. Immunostimulant agents from Andrographis paniculata. J Nat Prod 1993;56:995-9. PubMed
  8. Melchoir J, Spasov AA, Ostrovskij OV, et al. Double-blind, placebo-controlled pilot and phase III study of activity of standardized Andrographis paniculata Herba Nees extract fixed combination (Kan Jang) in the treatment of uncomplicated upper-respirator
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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