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Dietary supplement

Vegan Borage Oil Ingredients & Drug Interactions

by DEVA

Vegan Borage Oil label
See full label image
Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vegan Borage Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Vegan Borage Oil is a dietary supplement by DEVA with 1 active ingredient. Its ingredients are commonly taken for eczema and dry skin, rheumatoid arthritis, inflammation.Based on those ingredients, 226 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Borage Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vegan Borage Oil by DEVA

Ask about any prescription or over-the-counter medication and we check it for interactions with Vegan Borage Oil by DEVA — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vegan Borage Oil by DEVA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

DEVA Vegan Borage Oil contains one active ingredient: borage oil derived from the borage plant seed. Borage oil is a source of gamma-linolenic acid (GLA), an omega-6 fatty acid.

The inactive ingredients are a vegan capsule, organic orange oil, and silica.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Borage product and its label doesn't state a use — see Borage's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for borage oil is mixed and often sparse. It appears to be possibly ineffective for atopic dermatitis (eczema).

For attention deficit-hyperactivity disorder (ADHD), acute respiratory distress syndrome (ARDS), and alcoholism, there isn't enough reliable evidence in our data to rate whether it works.

The evidence, ingredient by ingredient Borage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, borage seed oil that's certified free of pyrrolizidine alkaloids (PA) is generally well tolerated. The most common side effects are mild digestive — belching, bloating, diarrhea, and soft stools.

However, borage plant parts like the leaf and flower can contain liver-toxic compounds (pyrrolizidine alkaloids), and chronic exposure can damage the liver and blood vessels. Because of this risk and concerns about PA contamination, borage oil should be avoided during pregnancy and breastfeeding.

Choose a product certified PA-free, and if you have liver disease or take medications that affect liver function, talk with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Borage

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Borage.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 227 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin, apixaban, or aspirin) — borage oil may increase bleeding risk. Also confirm if you take antipsychotics like chlorpromazine, or medications that induce CYP3A4 liver enzyme activity, as these carry documented interaction concerns.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

DEVA Vegan Borage Oil may be considered by people looking for a source of gamma-linolenic acid, though evidence for specific health claims is limited. Anyone taking blood thinners, antipsychotics, or medications that affect liver enzyme activity should check with their doctor or pharmacist first — interactions are documented.

Pregnant or nursing individuals should avoid it. Stick with a PA-certified product and discuss it with your own healthcare provider before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vegan Borage Oil, straight from the product label.

Brand DEVA
Barcode (UPC) 895634000256
Net contents 90 Vegan Cap(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 248199
Product type Fat/fatty Acid
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vegan Borage Oil by DEVA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
895634000256
IngredientAmount% DV
Calories10 Calorie(s)--
Calories from Fat10 Calorie(s)--
Total Fat1 Gram(s)2%
Borage Oil1000 mg--

Other ingredients: Vegan Capsule, organic Orange Oil, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

The Borage Oil used in this product is organic cold-pressed

This product does not contain animal products, derivatives or byproducts. 100% vegetarian, vegan. This product is registered with the vegan society.

Premium

Food sensitivity: Free of yeast, wheat, gluten, starch, soy, sugar, salt, hexane, dairy, egg, fish, artificial color.

Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) capsules daily with a meal or as directed by your health care provider.

Precautions

Warning: Always consult your doctor before taking dietary supplements.

Tamper evident: Do not use if imprinted seal under cap is broken.

Keep out of reach of children.

Seals/Symbols

The Vegan Society

Storage

Store in a cool, dry place.

Formula

GLA

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vegan Borage Oil by DEVA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vegan Borage Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vegan Borage Oil by DEVA

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Borage Oil

Interacts with
226 drugs
1000 mg per serving Form: Gamma Linolenic Acid

Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arth...

Borage Oil monograph & interactions

Other (inactive) ingredients: Vegan Capsule, Organic Orange Oil, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vegan Borage Oil by DEVA Drug Interactions

Want to check YOUR meds against Vegan Borage Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
226Drugs
226 Moderate

Ingredients driving the most interactions

Borage Oil 226

Individual Drug Interactions

The ingredients in Vegan Borage Oil interact with 226 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vegan Borage Oil interact with drugs. Each result below shows which ingredient is responsible. Borage Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Vegan Borage Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Borage Oil3 drug types · 226 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In healthy individuals, borage seed oil supplementation does not seem to affect platelet aggregation. However, gamma-linolenic acid, a constituent of borage seed oil, seems to decrease platelet aggregation by 45% and increase the risk of bleeding by 40% in animal and clinical research.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Inducers

Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Although borage seed oil contains little to no PAs, some borage plant parts, such as the leaf, flower, and seed, can contain hepatotoxic PAs. Hepatotoxic PAs are substrates of CYP3A4, which converts these chemicals into toxic metabolites. Tell patients to avoid borage preparations that are not certified and labeled as hepatotoxic PA-free.

Likelihood Possible Evidence D
Phenothiazines

Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Borage seed oil contains gamma-linolenic acid (GLA). There is concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines. This is based on limited data from two reports published in the 1980s. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with evening primrose, another source of GLA. However, none experienced an actual seizure. In the other report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily was added. One of these patients had a prior history of seizures. It is unclear whether evening primrose had any additive epileptogenic effects with the phenothiazines, but there is no evidence that taking GLA-containing supplements alone can cause seizures.

Likelihood Possible Evidence D
Borage Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vegan Borage Oil, from the product label.

DEVA

See all DEVA products
Name
DEVA Nutrition LLC
Phone Number
(888)988-3382
Web Address
www.devanutrition.com
Pharmacist Counseling Corner

Vegan Borage Oil by DEVA: Common Questions

Does Vegan Borage Oil by DEVA interact with any medications?
Yes. Based on its ingredients, Vegan Borage Oil has a known interaction with 226 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vegan Borage Oil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this borage oil upset my stomach?
Mild digestive upset is common and usually harmless. You might notice belching, bloating, diarrhea, or soft stools. These are the most frequent side effects when borage seed oil is taken by mouth.
Is this product safe during pregnancy or breastfeeding?
No — the safety data advises against it during both pregnancy and breastfeeding. The concern is possible liver-toxic alkaloids and theoretical harm to the uterus. If you're pregnant or nursing, talk with your doctor or pharmacist about whether this product is right for you.
What does gamma-linolenic acid (GLA) do?
GLA is an omega-6 fatty acid found in borage oil. It's the active component that research has studied for various health conditions, though evidence of benefit for most uses is still limited or mixed.
Does this product really work for eczema or ADHD?
For eczema, borage oil appears to be possibly ineffective based on available evidence. For ADHD, there isn't enough reliable evidence to say whether it works or not. Talk with your doctor or pharmacist about whether it might help in your case.
What's the difference between this product and borage supplements that aren't seed oil?
This product is borage seed oil, which contains very little to none of the liver-toxic compounds (pyrrolizidine alkaloids) found in other parts of the borage plant like the leaf and flower. That's why seed oil that's certified free of these alkaloids is generally better tolerated.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vegan Borage Oil is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vegan Borage Oil label
Go deeper

The Full Monographs Behind Vegan Borage Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Borage

Interacts with 226 drugs

Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arthritis with mixed results. The plant's le...

Read the full Borage monograph →
Sources

Sources & How We Checked

Vegan Borage Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Borage 11 references
  1. Guivernau M, Meza N, Barja P, Roman O. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. Prostaglandins Leukot Essent Fatty A PubMed
  2. WHO working group. Pyrrolizidine alkaloids. Environmental Health Criteria, 80. WHO: Geneva, 1988.
  3. Fan YY, Chapkin RS. Importance of dietary gamma-linolenic acid in human health and nutrition. J Nutr 1998;128:1411-4.
  4. Takwale A, Tan E, Agarwal S, et al. Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. BMJ 2003;327:1385. PubMed
  5. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. J Hepatol 2003;39:437-46. PubMed
  6. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Pharmazie 1995;50:83-98.
  7. Wang YP, Yan J, Fu PP, Chou MW. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Toxicol Lett 2005;155:411-20. PubMed
  8. Holman CP and Bell AF. A trial of evening primrose oil in the treatment of chronic schizophrenia. J Orhtomolecular Psych 1983;12:302-304.
  9. Vaddadi KS. The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. Prostaglandins Med 1981;6(4):375-379. PubMed
  10. Bard, J. M., Luc, G., Jude, B., Bordet, J. C., Lacroix, B., Bonte, J. P., Parra, H. J., and Duriez, P. A therapeutic dosage (3 g/day) of borage oil supplementation has no effect on platelet aggregation in healthy volunteers. Fundam.Clin.Pharmacol. 1997;1
  11. Puri BK. The safety of evening primrose oil in epilepsy. Prostaglandins Leukotrienes Essential Fatty Acids 2007;77:101-3. PubMed

See these in context on the Borage monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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