Everolimus
Generic name: Pronounced as (e'' ver oh' li mus)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 06/15/2018
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Other names
- Drug interactions
IMPORTANT WARNING
Taking everolimus may decrease your ability to fight infection from bacteria, viruses, and fungi and increase the risk that you will get a serious or life-threatening infection. If you have had hepatitis B (a type of liver disease) in the past, your infection may become active and you may develop symptoms during your treatment with everolimus. Tell your doctor if you have or have ever had hepatitis B or if you have or think you may have any type of infection now. Tell your doctor and pharmacist if you are taking other medications that suppress the immune system such as azathioprine (Imuran), cyclosporine (Gengraf, Neoral, Sandimmune), dexamethasone (Decadron, Dexpak), methotrexate (Rheumatrex, Trexall), prednisolone (Orapred, Pediapred, Prelone), prednisone (Sterapred), sirolimus (Rapamune), and tacrolimus (Prograf). If you experience any of the following symptoms, call your doctor immediately: excessive tiredness; yellowing of the skin or eyes; loss of appetite; nausea; joint pain; dark urine; pale stools; pain in the upper right part of the stomach; rash; difficult, painful, or frequent urination; ear pain or drainage; sinus pain and pressure; or sore throat, cough, fever, chills, feeling unwell or other signs of infection.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to everolimus.
Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide [Zortress] or patient information leaflet [Afinitor, Afinitor Disperz]) when you begin treatment with everolimus and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.
Talk to your doctor about the risks of taking everolimus.
For patients who are taking everolimus to prevent transplant rejection:
You must take everolimus under the supervision of a doctor who is experienced in taking care of transplant patients and giving medications that suppress the immune system.
The risk that you will develop cancer, especially lymphoma (cancer of a part of the immune system) or skin cancer is increased during your treatment with everolimus. Tell your doctor if you or anyone in your family has or has ever had skin cancer or if you have fair skin. To reduce your risk of skin cancer, plan to avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen during your treatment. If you experience any of the following symptoms, call your doctor immediately: a red, raised, or waxy area on the skin; new sores, bumps, or discoloration on the skin; sores that do not heal; lumps or masses anywhere in your body; skin changes; night sweats; swollen glands in the neck, armpits, or groin; trouble breathing; chest pain; or weakness or tiredness that does not go away.
Taking everolimus may increase the risk that you will develop certain very rare and serious infections, including infection with the BK virus, a serious virus that may damage the kidneys and cause a transplanted kidney to fail), and progressive multifocal leukoencephalopathy (PML; a rare infection of the brain that cannot be treated, prevented, or cured and that usually causes death or severe disability). Call your doctor immediately if you experience any of the following symptoms of PML: weakness on one side of the body that worsens over time; clumsiness of the arms or legs; changes in your thinking, walking, balance, speech, eyesight, or strength that last several days; headaches; seizures; confusion; or personality changes.
Everolimus may cause a blood clot in the blood vessels of your transplanted kidney. This is most likely to happen within the first 30 days after your kidney transplant and may cause the transplant to be unsuccessful. If you experience any of the following symptoms, call your doctor immediately: pain in your groin, lower back, side, or stomach; decreased urination or no urination; blood in your urine; dark-colored urine; fever; nausea; or vomiting.
Taking everolimus in combination with cyclosporine could cause damage to your kidneys. In order to reduce this risk, your doctor will adjust the dose of cyclosporine and monitor the levels of the medications and how your kidneys are working. If you experience either of the following symptoms, call your doctor immediately: decreased urination or swelling of the arms, hands, feet, ankles, or lower legs.
In clinical studies, more people who took everolimus died during the first few months after receiving a heart transplant than people who did not take everolimus. If you have received a heart transplant, talk to your doctor about the risks of taking everolimus.
Why is this medication prescribed?
Everolimus (Afinitor) is used to treat advanced renal cell carcinoma (RCC; cancer that begins in the kidneys) that has already been treated unsuccessfully with other medications. Everolimus (Afinitor) is also used to treat a certain type of advanced breast cancer that has already been treated with at least one other medication. Everolimus (Afinitor) is also used to treat a certain type of cancer of the pancreas, stomach, intestines, or lungs that has spread or progressed and that cannot be treated with surgery. Everolimus (Afinitor) is also used to treat kidney tumors in people with tuberous sclerosis complex (TSC; a genetic condition that causes tumors to grow in many organs). Everolimus (Afinitor and Afinitor Disperz) is also used to treat subependymal giant cell astrocytoma (SEGA; a type of brain tumor) in adults and children 1 year of age and older who have TSC. Everolimus (Afinitor Disperz) is also used along with other medications to treat certain types of seizures in adults and children 2 years of age and older who have TSC. Everolimus (Zortress) is used with other medications to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in certain adults who have received kidney transplants. Everolimus is in a class of medications called kinase inhibitors. Everolimus treats cancer by stopping cancer cells from reproducing and by decreasing blood supply to the cancer cells. Everolimus prevents transplant rejection by decreasing the activity of the immune system.
How should this medicine be used?
Everolimus comes as a tablet to take by mouth and as a tablet to suspend in water and take by mouth. When everolimus is taken to treat kidney tumors, SEGA, or seizures in people who have TSC; RCC; or breast, pancreatic, stomach, intestine, or lung cancer, it is usually taken once a day. When everolimus is taken to prevent transplant rejection, it is usually taken twice a day (every 12 hours) at the same time as cyclosporine. Everolimus should either always be taken with food or always without food. Take everolimus at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take everolimus exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Everolimus tablets come in individual blister packs that can be opened with scissors. Do not open a blister pack until you are ready to swallow the tablet it contains.
You should take either everolimus tablets or everolimus tablets for oral suspension. Do not take a combination of both of these products.
Swallow the tablets whole with a full glass of water; do not split, chew, or crush them. Do not take tablets that have been crushed or broken. Tell your doctor or pharmacist if you are not able to swallow the tablets whole.
If you are taking the tablets for oral suspension (Afinitor Disperz), you must mix them with water before use. Do not swallow these tablets whole, and do not mix them with juice or any liquid other than water. Do not prepare the mixture more than 60 minutes before you plan to use it, and dispose of the mixture if it is not used after 60 minutes. Do not prepare the medication on a surface that you use to prepare or eat food. If you will be preparing the medication for someone else, you should wear gloves to prevent contact with the medication. If you are pregnant or plan to become pregnant, you should avoid preparing the medication for someone else, because contact with everolimus may harm your unborn baby.
You can mix the tablets for oral suspension in an oral syringe or in a small glass. To prepare the mixture in an oral syringe, remove the plunger from a 10-mL oral syringe and place the prescribed number of tablets in the barrel of the syringe without breaking or crushing the tablets. You can prepare up to 10 mg of everolimus in a syringe at one time, so if your dose is greater than 10 mg, you will need to prepare it in a second syringe. Replace the plunger in the syringe and draw about 5 mL of water and 4 mL of air into the syringe and place the syringe into a container with the tip pointing up. Wait 3 minutes to allow the tablets to go into suspension. then pick up the syringe and gently turn it up and down it five times. Place the syringe into the patient's mouth and push the plunger to administer the medication. After the patient has swallowed the medication, refill the same syringe with 5 mL of water and 4 mL of air and swirl the syringe to rinse out any particles that are still in the syringe. Give this mixture to the patient to be sure that he or she receives all of the medication.
To prepare the mixture in a glass, place the prescribed number of tablets into a small drinking glass that holds no more than 100 mL (about 3 ounces) without crushing or breaking the tablets. You can prepare up to 10 mg of everolimus in a glass at one time, so if your dose is greater than 10 mg, you will need to prepare it in a second glass. Add 25 mL (about 1 ounce) of water to the glass. Wait 3 minutes and then gently stir the mixture with a spoon. Have the patient drink the entire mixture immediately. Add another 25 mL of water to the glass and stir with the same spoon to rinse out any particles that are still in the glass. Have the patient drink this mixture to be sure that he or she receives all of the medication.
Your doctor may adjust your dose of everolimus during your treatment depending on the results of your blood tests, your response to the medication, side effects you experience, and changes in other medications that you take with everolimus. If you are taking everolimus to treat SEGA or seizures, your doctor will adjust your dose not more often than once every 1 to 2 weeks, and if you are taking everolimus to prevent transplant rejection, your doctor will adjust your dose not more often than once every 4 to 5 days. Your doctor may stop your treatment for a time if you experience severe side effects. Talk to your doctor about how you are feeling during your treatment with everolimus.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking everolimus,
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tell your doctor and pharmacist if you are allergic to everolimus, sirolimus (Rapamune), temsirolimus (Torisel), any other medications, or any of the ingredients in everolimus tablets. Ask your pharmacist for a list of the ingredients.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc) perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik); amprenavir (Agenerase), atazanavir (Reyataz),aprepitant (Emend), carbamazepine (Carbatrol, Epitol, Tegretol),clarithromycin (Biaxin, in Prevpac), digoxin (Digitek, Lanoxicaps, Lanoxin), diltiazem (Cardizem, Dilacor, Tiazac), efavirenz (in Atripla, Sustiva), erythromycin (E.E.S., E-Mycin, Erythrocin), fluconazole (Diflucan), fosamprenavir (Lexiva), indinavir (Crixivan), itraconazole (Sporanox), ketoconazole (Nizoral), nelfinavir (Viracept), nefazodone, nevirapine (Viramune), nicardipine (Cardene), phenobarbital (Luminal), phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), rifampin (Rifadin, in Rifamate, in Rifater), rifapentine (Priftin), ritonavir (Norvir, in Kaletra), saquinavir (Invirase),telithromycin (Ketek), verapamil (Calan, Covera, Isoptin, Verelan).and voriconazole (Vfend). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with everolimus, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
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tell your doctor what herbal products you are taking, especially St. John's wort.
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tell your doctor if you have or have ever had diabetes or high blood sugar; high levels of cholesterol or triglycerides in your blood; kidney or liver disease; or any condition that prevents you from digesting foods containing sugar, starch, or dairy products normally.
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tell your doctor if you are pregnant or plan to become pregnant If you are a woman who is able to become pregnant, you must use effective birth control during your treatment and for 8 weeks after your final dose. If you are male with a female partner who could become pregnant, you must use effective birth control during your treatment and for 4 weeks after your final dose. Talk to your doctor about methods of birth control that will work for you. If you or your partner become pregnant while taking everolimus, call your doctor. Everolimus may harm the fetus.
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tell your doctor if you are breastfeeding. Do not breastfeed during your treatment and for 2 weeks after your final dose.
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if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking everolimus.
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do not have any vaccinations without talking to your doctor. During your treatment with everolimus, you should avoid close contact with other people who have recently been vaccinated.
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talk to your child's doctor about vaccinations that your child may need to receive before beginning his or her treatment with everolimus.
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you should know that you may develop sores or swelling in your mouth during your treatment with everolimus, especially during the first 8 weeks of treatment. When you start treatment with everolimus, your doctor may prescribe a certain mouthwash to reduce the chance that you will get mouth ulcers or sores and to reduce their severity. Follow your doctor's instructions on how to use this mouthwash. Tell your doctor if you develop sores or feel pain in your mouth. You should not use any mouthwash without talking to your doctor or pharmacist because certain types of mouthwash that contain alcohol, peroxide, iodine, or thyme can worsen the sores and swelling.
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you should know that wounds or cuts, including the cut in the skin made during a kidney transplant may heal more slowly than normal or may not heal properly during your treatment with everolimus. Call your doctor right away if the cut in the skin from your kidney transplant or any other wound becomes warm, red, painful, or swollen; fills with blood, fluid, or pus; or begins to open.
What special dietary instructions should I follow?
Do not eat grapefruit or drink grapefruit juice while taking this medication.
What should I do if I forget a dose?
If you remember the missed dose within 6 hours of the time you were scheduled to take it, take the missed dose right away. However, if more than 6 hours have passed since the scheduled time, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Everolimus may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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diarrhea
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constipation
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change in ability to taste food
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weight loss
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dry mouth
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weakness
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headache
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difficulty falling asleep or staying asleep
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nosebleed
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dry skin
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acne
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problems with nails
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hair loss
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pain in the arms, legs, back or joints
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muscle cramps
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missed or irregular menstrual periods
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heavy menstrual bleeding
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difficulty getting or keeping an erection
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anxiety
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aggression or other changes in behavior
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Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
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hives
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itching
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swelling of the hands, feet, arms, legs, eyes, face, mouth, lips, tongue, or throat
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hoarseness
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difficulty breathing or swallowing
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wheezing
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flushing
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chest pain
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extreme thirst or hunger
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unusual bleeding or bruising
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pale skin
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fast or irregular heartbeat
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dizziness
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seizures
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Everolimus may decrease fertility in men and women. Talk to your doctor about the risks of taking everolimus.
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Everolimus may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the blister pack it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light and excess heat and moisture (not in the bathroom). Keep the blister packs and tablets dry.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
What OTHER INFORMATION should I know?
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Repaglinide | Repaglinide The serum concentration of Repaglinide can be increased when it is combined with Everolimus. |
Insulin Glargine (rDNA origin) Injection | Insulin Glargine (rDNA origin) Injection The therapeutic efficacy of Insulin glargine can be decreased when used in combination with Everolimus. |
Leflunomide | Leflunomide The risk or severity of adverse effects can be increased when Everolimus is combined with Leflunomide. |
Delavirdine | Delavirdine The metabolism of Delavirdine can be decreased when combined with Everolimus. |
Nevirapine | Nevirapine The metabolism of Nevirapine can be decreased when combined with Everolimus. |
Atorvastatin | Atorvastatin The risk or severity of adverse effects can be increased when Everolimus is combined with Atorvastatin. |
Dolasetron | Dolasetron The metabolism of Dolasetron can be decreased when combined with Everolimus. |
Aminophylline | Aminophylline The metabolism of Aminophylline can be decreased when combined with Everolimus. |
Anagrelide | Anagrelide The risk or severity of bleeding can be increased when Anagrelide is combined with Everolimus. |
Cilostazol | Cilostazol The metabolism of Everolimus can be decreased when combined with Cilostazol. |
Clopidogrel | Clopidogrel The risk or severity of bleeding can be increased when Clopidogrel is combined with Everolimus. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The metabolism of Everolimus can be decreased when combined with Erythromycin. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) The excretion of Conjugated estrogens can be decreased when combined with Everolimus. |
Fenofibrate | Fenofibrate The metabolism of Everolimus can be decreased when combined with Fenofibrate. |
Methylergonovine | Methylergonovine The metabolism of Everolimus can be decreased when combined with Methylergometrine. |
Miglitol | Miglitol The therapeutic efficacy of Miglitol can be decreased when used in combination with Everolimus. |
Mycophenolate | Mycophenolate The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Everolimus. |
Paregoric | Paregoric The serum concentration of Everolimus can be increased when it is combined with Morphine. |
Penbutolol | Penbutolol The metabolism of Acebutolol can be decreased when combined with Everolimus. |
Prednisone | Prednisone The serum concentration of Everolimus can be increased when it is combined with Prednisone. |
Reserpine | Reserpine The serum concentration of Everolimus can be increased when it is combined with Reserpine. |
Sumatriptan | Sumatriptan The excretion of Sumatriptan can be decreased when combined with Everolimus. |
Tacrolimus | Tacrolimus Tacrolimus may increase the immunosuppressive activities of Everolimus. |
Triamcinolone | Triamcinolone Triamcinolone may decrease the excretion rate of Everolimus which could result in a higher serum level. |
Doxycycline Injection | Doxycycline Injection The metabolism of Everolimus can be decreased when combined with Doxycycline. |
Fluconazole Injection | Fluconazole Injection The metabolism of Everolimus can be decreased when combined with Fluconazole. |
Interferon Beta-1b Injection | Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Everolimus. |
Interferon Gamma-1b Injection | Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Everolimus. |
Meperidine Injection | Meperidine Injection The metabolism of Everolimus can be increased when combined with Meperidine. |
Methylprednisolone Injection | Methylprednisolone Injection The serum concentration of Everolimus can be increased when it is combined with Methylprednisolone. |
Metoclopramide Injection | Metoclopramide Injection The metabolism of Metoclopramide can be decreased when combined with Everolimus. |
Metronidazole Injection | Metronidazole Injection The metabolism of Everolimus can be decreased when combined with Metronidazole. |
Morphine Injection | Morphine Injection The serum concentration of Everolimus can be increased when it is combined with Morphine. |
Zidovudine Injection | Zidovudine Injection The risk or severity of adverse effects can be increased when Zidovudine is combined with Everolimus. |
Altretamine | Altretamine The metabolism of Amphetamine can be decreased when combined with Everolimus. |
Cyclosporine | Cyclosporine The serum concentration of Everolimus can be increased when it is combined with Cyclosporine. |
Ondansetron | Ondansetron The metabolism of Everolimus can be decreased when combined with Ondansetron. |
Enoxaparin Injection | Enoxaparin Injection The risk or severity of bleeding can be increased when Enoxaparin is combined with Everolimus. |
Torsemide | Torsemide The excretion of Torasemide can be decreased when combined with Everolimus. |
Olanzapine | Olanzapine The metabolism of Olanzapine can be decreased when combined with Everolimus. |
Hydroxychloroquine | Hydroxychloroquine The risk or severity of adverse effects can be increased when Everolimus is combined with Hydroxychloroquine. |
Orlistat | Orlistat The metabolism of Everolimus can be increased when combined with Orlistat. |
Oxcarbazepine | Oxcarbazepine The metabolism of Oxcarbazepine can be increased when combined with Everolimus. |
Temozolomide | Temozolomide The risk or severity of adverse effects can be increased when Temozolomide is combined with Everolimus. |
Anakinra | Anakinra The metabolism of Everolimus can be increased when combined with Anakinra. |
Linezolid | Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Everolimus. |
Pentosan Polysulfate | Pentosan Polysulfate The risk or severity of bleeding can be increased when Pentosan polysulfate is combined with Everolimus. |
Trimipramine | Trimipramine The metabolism of Trimipramine can be decreased when combined with Everolimus. |
Etanercept Injection | Etanercept Injection The metabolism of Everolimus can be increased when combined with Etanercept. |
Modafinil | Modafinil The metabolism of Everolimus can be increased when combined with Modafinil. |
Perindopril | Perindopril The risk or severity of adverse effects can be increased when Everolimus is combined with Perindopril. |
Tenofovir | Tenofovir The metabolism of Everolimus can be decreased when combined with Tenofovir. |
Sirolimus | Sirolimus The metabolism of Sirolimus can be decreased when combined with Everolimus. |
Epinephrine Injection | Epinephrine Injection The metabolism of Everolimus can be decreased when combined with Epinephrine. |
Epirubicin | Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Everolimus. |
Escitalopram | Escitalopram The metabolism of Escitalopram can be decreased when combined with Everolimus. |
Zonisamide | Zonisamide The serum concentration of Everolimus can be increased when it is combined with Zonisamide. |
Adalimumab Injection | Adalimumab Injection The metabolism of Everolimus can be increased when combined with Adalimumab. |
Aripiprazole | Aripiprazole The metabolism of Everolimus can be decreased when combined with Aripiprazole. |
Atomoxetine | Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Everolimus. |
Ezetimibe | Ezetimibe The excretion of Ezetimibe can be decreased when combined with Everolimus. |
Glatiramer Injection | Glatiramer Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Glatiramer. |
Atazanavir | Atazanavir The metabolism of Everolimus can be decreased when combined with Atazanavir. |
Almotriptan | Almotriptan The metabolism of Almotriptan can be decreased when combined with Everolimus. |
Eletriptan | Eletriptan The metabolism of Everolimus can be decreased when combined with Eletriptan. |
Mefloquine | Mefloquine The metabolism of Everolimus can be decreased when combined with Mefloquine. |
Rosuvastatin | Rosuvastatin The metabolism of Everolimus can be decreased when combined with Rosuvastatin. |
Vardenafil | Vardenafil The metabolism of Everolimus can be decreased when combined with Vardenafil. |
Alfuzosin | Alfuzosin The metabolism of Everolimus can be decreased when combined with Alfuzosin. |
Aprepitant | Aprepitant The metabolism of Everolimus can be decreased when combined with Aprepitant. |
Tegaserod | Tegaserod The serum concentration of Everolimus can be increased when it is combined with Tegaserod. |
Progesterone | Progesterone The metabolism of Everolimus can be increased when combined with Progesterone. |
Darbepoetin Alfa Injection | Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Everolimus. |
Infliximab Injection | Infliximab Injection The metabolism of Everolimus can be increased when combined with Infliximab. |
Protriptyline | Protriptyline The metabolism of Protriptyline can be decreased when combined with Everolimus. |
Rifaximin | Rifaximin The metabolism of Everolimus can be increased when combined with Rifaximin. |
Duloxetine | Duloxetine The metabolism of Everolimus can be decreased when combined with Duloxetine. |
Norethindrone | Norethindrone The metabolism of Everolimus can be decreased when combined with Norethisterone. |
Bosentan | Bosentan The metabolism of Everolimus can be increased when combined with Bosentan. |
Natalizumab Injection | Natalizumab Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Natalizumab. |
Erlotinib | Erlotinib The metabolism of Everolimus can be decreased when combined with Erlotinib. |
Eszopiclone | Eszopiclone The metabolism of Everolimus can be decreased when combined with Eszopiclone. |
Insulin Aspart (rDNA Origin) Injection | Insulin Aspart (rDNA Origin) Injection The therapeutic efficacy of Insulin aspart can be decreased when used in combination with Everolimus. |
Palifermin | Palifermin The therapeutic efficacy of Palifermin can be decreased when used in combination with Everolimus. |
Solifenacin | Solifenacin The metabolism of Solifenacin can be decreased when combined with Everolimus. |
Voriconazole | Voriconazole The metabolism of Everolimus can be decreased when combined with Voriconazole. |
Dextroamphetamine | Dextroamphetamine The metabolism of Amphetamine can be decreased when combined with Everolimus. |
Peginterferon Alfa-2a Injection | Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Everolimus. |
Peginterferon Alfa-2b (PEG-Intron) | Peginterferon Alfa-2b (PEG-Intron) The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Everolimus. |
Pramlintide Injection | Pramlintide Injection The therapeutic efficacy of Pramlintide can be decreased when used in combination with Everolimus. |
Exenatide Injection | Exenatide Injection The therapeutic efficacy of Exenatide can be decreased when used in combination with Everolimus. |
Darifenacin | Darifenacin The metabolism of Darifenacin can be decreased when combined with Everolimus. |
Fentanyl | Fentanyl The metabolism of Everolimus can be decreased when combined with Fentanyl. |
Deferasirox | Deferasirox The metabolism of Everolimus can be increased when combined with Deferasirox. |
Tipranavir | Tipranavir The serum concentration of Everolimus can be increased when it is combined with Tipranavir. |
Felbamate | Felbamate The metabolism of Everolimus can be increased when combined with Felbamate. |
Insulin Detemir (rDNA Origin) Injection | Insulin Detemir (rDNA Origin) Injection The therapeutic efficacy of Insulin detemir can be decreased when used in combination with Everolimus. |
Ranolazine | Ranolazine The serum concentration of Everolimus can be increased when it is combined with Ranolazine. |
Abatacept Injection | Abatacept Injection The metabolism of Everolimus can be increased when combined with Abatacept. |
Imatinib | Imatinib The metabolism of Everolimus can be decreased when combined with Imatinib. |
Sitagliptin | Sitagliptin The serum concentration of Everolimus can be increased when it is combined with Sitagliptin. |
Bevacizumab Injection | Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Everolimus. |
Gefitinib | Gefitinib The metabolism of Everolimus can be decreased when combined with Gefitinib. |
Paliperidone | Paliperidone The serum concentration of Everolimus can be increased when it is combined with Paliperidone. |
Bortezomib | Bortezomib The risk or severity of adverse effects can be increased when Everolimus is combined with Bortezomib. |
Clofarabine Injection | Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Everolimus. |
Hepatitis B Vaccine | Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Everolimus. |
Influenza Vaccine, Inactivated or Recombinant | Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Everolimus. |
Influenza Vaccine, Live Intranasal | Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Everolimus. |
Live Shingles (Zoster) Vaccine (ZVL) | Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Everolimus. |
Insulin Glulisine (rDNA origin) Injection | Insulin Glulisine (rDNA origin) Injection The therapeutic efficacy of Insulin glulisine can be decreased when used in combination with Everolimus. |
Oxaliplatin Injection | Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Everolimus. |
Posaconazole | Posaconazole The metabolism of Posaconazole can be decreased when combined with Everolimus. |
Primaquine | Primaquine The metabolism of Everolimus can be decreased when combined with Primaquine. |
Rituximab Injection | Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Everolimus. |
Darunavir | Darunavir The serum concentration of Everolimus can be increased when it is combined with Darunavir. |
Pemetrexed Injection | Pemetrexed Injection The risk or severity of adverse effects can be increased when Pemetrexed is combined with Everolimus. |
Lisdexamfetamine | Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Everolimus. |
Retapamulin | Retapamulin The metabolism of Retapamulin can be decreased when combined with Everolimus. |
Vorinostat | Vorinostat The risk or severity of adverse effects can be increased when Everolimus is combined with Vorinostat. |
Sorafenib | Sorafenib The serum concentration of Everolimus can be increased when it is combined with Sorafenib. |
Sunitinib | Sunitinib The metabolism of Everolimus can be decreased when combined with Sunitinib. |
Lapatinib | Lapatinib The serum concentration of Everolimus can be increased when it is combined with Lapatinib. |
Dasatinib | Dasatinib The metabolism of Dasatinib can be decreased when combined with Everolimus. |
Mexiletine | Mexiletine The metabolism of Mexiletine can be decreased when combined with Everolimus. |
Armodafinil | Armodafinil The metabolism of Everolimus can be increased when combined with Armodafinil. |
Azacitidine Injection | Azacitidine Injection The risk or severity of adverse effects can be increased when Azacitidine is combined with Everolimus. |
Ivermectin | Ivermectin The metabolism of Everolimus can be increased when combined with Ivermectin. |
Temsirolimus | Temsirolimus The serum concentration of Temsirolimus can be increased when it is combined with Everolimus. |
Nelarabine Injection | Nelarabine Injection The risk or severity of adverse effects can be increased when Nelarabine is combined with Everolimus. |
Lenalidomide | Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Everolimus. |
Nilotinib | Nilotinib The serum concentration of Everolimus can be increased when it is combined with Nilotinib. |
Toremifene | Toremifene The serum concentration of Everolimus can be increased when it is combined with Toremifene. |
Bexarotene | Bexarotene The metabolism of Everolimus can be increased when combined with Bexarotene. |
Budesonide | Budesonide The serum concentration of Everolimus can be increased when it is combined with Budesonide. |
Chloramphenicol Injection | Chloramphenicol Injection The metabolism of Everolimus can be decreased when combined with Chloramphenicol. |
Decitabine Injection | Decitabine Injection The risk or severity of adverse effects can be increased when Decitabine is combined with Everolimus. |
Etravirine | Etravirine The metabolism of Everolimus can be increased when combined with Etravirine. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Arsenic trioxide. |
Mitoxantrone Injection | Mitoxantrone Injection The metabolism of Everolimus can be decreased when combined with Mitoxantrone. |
Desvenlafaxine | Desvenlafaxine The metabolism of Everolimus can be decreased when combined with Desvenlafaxine. |
Cevimeline | Cevimeline The metabolism of Cevimeline can be decreased when combined with Everolimus. |
Nebivolol | Nebivolol The metabolism of Nebivolol can be decreased when combined with Everolimus. |
Tretinoin | Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Everolimus. |
Bendamustine Injection | Bendamustine Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Bendamustine. |
Pilocarpine | Pilocarpine The metabolism of Everolimus can be decreased when combined with Pilocarpine. |
Flecainide | Flecainide The metabolism of Flecainide can be decreased when combined with Everolimus. |
Certolizumab Injection | Certolizumab Injection The metabolism of Everolimus can be increased when combined with Certolizumab pegol. |
Ixabepilone Injection | Ixabepilone Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Ixabepilone. |
Irinotecan Injection | Irinotecan Injection The risk or severity of adverse effects can be increased when Irinotecan is combined with Everolimus. |
Estramustine | Estramustine The risk or severity of adverse effects can be increased when Estramustine is combined with Everolimus. |
Mitotane | Mitotane The metabolism of Everolimus can be increased when combined with Mitotane. |
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) | Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Everolimus. |
Rufinamide | Rufinamide The metabolism of Everolimus can be increased when combined with Rufinamide. |
Silodosin | Silodosin The serum concentration of Silodosin can be increased when it is combined with Everolimus. |
Midazolam | Midazolam The serum concentration of Midazolam can be increased when it is combined with Everolimus. |
Dexrazoxane Injection | Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Everolimus. |
Ibritumomab Injection | Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Everolimus. |
Milnacipran | Milnacipran The metabolism of Everolimus can be decreased when combined with Milnacipran. |
Fesoterodine | Fesoterodine The metabolism of Everolimus can be decreased when combined with Fesoterodine. |
Betaxolol | Betaxolol The metabolism of Betaxolol can be decreased when combined with Everolimus. |
Iloperidone | Iloperidone The metabolism of Everolimus can be decreased when combined with Iloperidone. |
Prasugrel | Prasugrel The risk or severity of bleeding can be increased when Prasugrel is combined with Everolimus. |
Lacosamide | Lacosamide The metabolism of Everolimus can be decreased when combined with Lacosamide. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The serum concentration of Tolvaptan can be increased when it is combined with Everolimus. |
Dronedarone | Dronedarone The metabolism of Dronedarone can be decreased when combined with Everolimus. |
Pralatrexate Injection | Pralatrexate Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Pralatrexate. |
Palonosetron Injection | Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Everolimus. |
Saxagliptin | Saxagliptin The therapeutic efficacy of Saxagliptin can be decreased when used in combination with Everolimus. |
Romidepsin Injection | Romidepsin Injection The serum concentration of Romidepsin can be increased when it is combined with Everolimus. |
Tapentadol | Tapentadol The metabolism of Tapentadol can be decreased when combined with Everolimus. |
Topotecan | Topotecan The metabolism of Everolimus can be decreased when combined with Topotecan. |
Golimumab Injection | Golimumab Injection The metabolism of Everolimus can be increased when combined with Golimumab. |
Pazopanib | Pazopanib The metabolism of Everolimus can be decreased when combined with Pazopanib. |
Pitavastatin | Pitavastatin The excretion of Pitavastatin can be decreased when combined with Everolimus. |
Albendazole | Albendazole The metabolism of Everolimus can be decreased when combined with Albendazole. |
Oxymorphone | Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Everolimus. |
Denosumab Injection | Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Everolimus. |
Dabigatran | Dabigatran The risk or severity of bleeding can be increased when Dabigatran is combined with Everolimus. |
Liraglutide Injection | Liraglutide Injection The therapeutic efficacy of Liraglutide can be decreased when used in combination with Everolimus. |
Tocilizumab Injection | Tocilizumab Injection The metabolism of Everolimus can be increased when combined with Tocilizumab. |
Fingolimod | Fingolimod Everolimus may increase the immunosuppressive activities of Fingolimod. |
Eribulin Injection | Eribulin Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Eribulin. |
Cabazitaxel Injection | Cabazitaxel Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Cabazitaxel. |
Acetaminophen Injection | Acetaminophen Injection The metabolism of Everolimus can be increased when combined with Acetaminophen. |
Vilazodone | Vilazodone The metabolism of Vilazodone can be decreased when combined with Everolimus. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection The metabolism of Everolimus can be decreased when combined with Aldesleukin. |
Sipuleucel-T Injection | Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Everolimus. |
Belimumab Injection | Belimumab Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Belimumab. |
Busulfan Injection | Busulfan Injection The risk or severity of adverse effects can be increased when Busulfan is combined with Everolimus. |
Roflumilast | Roflumilast Roflumilast may increase the immunosuppressive activities of Everolimus. |
Linagliptin | Linagliptin The metabolism of Everolimus can be decreased when combined with Linagliptin. |
Rilpivirine | Rilpivirine The metabolism of Everolimus can be decreased when combined with Rilpivirine. |
Telaprevir | Telaprevir The serum concentration of Everolimus can be increased when it is combined with Glecaprevir. |
Cyclophosphamide Injection | Cyclophosphamide Injection The metabolism of Everolimus can be increased when combined with Cyclophosphamide. |
Rivaroxaban | Rivaroxaban The serum concentration of Rivaroxaban can be increased when it is combined with Everolimus. |
Ticagrelor | Ticagrelor The serum concentration of Everolimus can be increased when it is combined with Ticagrelor. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The metabolism of Everolimus can be decreased when combined with Brentuximab vedotin. |
Ruxolitinib | Ruxolitinib The risk or severity of adverse effects can be increased when Everolimus is combined with Ruxolitinib. |
Vandetanib | Vandetanib The serum concentration of Everolimus can be increased when it is combined with Vandetanib. |
Clobazam | Clobazam The metabolism of Clobazam can be increased when combined with Everolimus. |
Vemurafenib | Vemurafenib The serum concentration of Everolimus can be increased when it is combined with Vemurafenib. |
Belatacept Injection | Belatacept Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Belatacept. |
Ivacaftor | Ivacaftor The serum concentration of Everolimus can be increased when it is combined with Ivacaftor. |
Basiliximab Injection | Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Everolimus. |
Axitinib | Axitinib The serum concentration of Axitinib can be increased when it is combined with Everolimus. |
Crizotinib | Crizotinib The metabolism of Everolimus can be decreased when combined with Crizotinib. |
Melphalan Injection | Melphalan Injection The risk or severity of adverse effects can be increased when Melphalan is combined with Everolimus. |
Cabergoline | Cabergoline The metabolism of Everolimus can be decreased when combined with Cabergoline. |
Naloxone Injection | Naloxone Injection The metabolism of Everolimus can be decreased when combined with Naloxone. |
Ambrisentan | Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Everolimus. |
Eculizumab Injection | Eculizumab Injection The risk or severity of adverse effects can be increased when Eculizumab is combined with Everolimus. |
Fondaparinux Injection | Fondaparinux Injection The risk or severity of bleeding can be increased when Fondaparinux is combined with Everolimus. |
Carfilzomib Injection | Carfilzomib Injection The serum concentration of Carfilzomib can be increased when it is combined with Everolimus. |
Iloprost | Iloprost The risk or severity of bleeding can be increased when Iloprost is combined with Everolimus. |
Enzalutamide | Enzalutamide The metabolism of Everolimus can be increased when combined with Enzalutamide. |
Mirabegron | Mirabegron The serum concentration of Everolimus can be increased when it is combined with Mirabegron. |
Regorafenib | Regorafenib The serum concentration of Everolimus can be increased when it is combined with Regorafenib. |
Bosutinib | Bosutinib The metabolism of Everolimus can be decreased when combined with Bosutinib. |
Corticotropin, Repository Injection | Corticotropin, Repository Injection The serum concentration of Everolimus can be increased when it is combined with Corticotropin. |
Teriflunomide | Teriflunomide The risk or severity of adverse effects can be increased when Everolimus is combined with Teriflunomide. |
Lorcaserin | Lorcaserin The therapeutic efficacy of Mecasermin can be decreased when used in combination with Everolimus. |
Icosapent Ethyl | Icosapent Ethyl The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Everolimus. |
Tofacitinib | Tofacitinib Everolimus may increase the immunosuppressive activities of Tofacitinib. |
Alogliptin | Alogliptin The metabolism of Alogliptin can be decreased when combined with Everolimus. |
Dimethyl Fumarate | Dimethyl Fumarate The risk or severity of adverse effects can be increased when Everolimus is combined with Dimethyl fumarate. |
Ponatinib | Ponatinib The serum concentration of Everolimus can be increased when it is combined with Ponatinib. |
Pomalidomide | Pomalidomide The risk or severity of adverse effects can be increased when Pomalidomide is combined with Everolimus. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The metabolism of Everolimus can be decreased when combined with Trastuzumab emtansine. |
Apixaban | Apixaban The serum concentration of Apixaban can be increased when it is combined with Everolimus. |
Canagliflozin | Canagliflozin The serum concentration of Everolimus can be increased when it is combined with Canagliflozin. |
Dabrafenib | Dabrafenib The metabolism of Everolimus can be increased when combined with Dabrafenib. |
Trametinib | Trametinib The metabolism of Everolimus can be increased when combined with Trametinib. |
Dolutegravir | Dolutegravir The serum concentration of Dolutegravir can be increased when it is combined with Everolimus. |
Afatinib | Afatinib The serum concentration of Everolimus can be increased when it is combined with Afatinib. |
Levomilnacipran | Levomilnacipran The metabolism of Everolimus can be decreased when combined with Levomilnacipran. |
Vortioxetine | Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Everolimus. |
Perampanel | Perampanel The metabolism of Everolimus can be increased when combined with Perampanel. |
Ibrutinib | Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Everolimus. |
Lomitapide | Lomitapide The serum concentration of Everolimus can be increased when it is combined with Lomitapide. |
Obinutuzumab Injection | Obinutuzumab Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Obinutuzumab. |
Simeprevir | Simeprevir The metabolism of Everolimus can be decreased when combined with Simeprevir. |
Sofosbuvir | Sofosbuvir The serum concentration of Sofosbuvir can be increased when it is combined with Everolimus. |
Dapagliflozin | Dapagliflozin The metabolism of Everolimus can be decreased when combined with Dapagliflozin. |
Apremilast | Apremilast The metabolism of Everolimus can be increased when combined with Apremilast. |
Ceritinib | Ceritinib The metabolism of Everolimus can be decreased when combined with Ceritinib. |
Siltuximab Injection | Siltuximab Injection The metabolism of Everolimus can be increased when combined with Siltuximab. |
Albiglutide Injection | Albiglutide Injection The therapeutic efficacy of Albiglutide can be decreased when used in combination with Everolimus. |
Eslicarbazepine | Eslicarbazepine The metabolism of Everolimus can be increased when combined with Eslicarbazepine. |
Vedolizumab Injection | Vedolizumab Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Vedolizumab. |
Belinostat Injection | Belinostat Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Belinostat. |
Idelalisib | Idelalisib The risk or severity of adverse effects can be increased when Idelalisib is combined with Everolimus. |
Testosterone Injection | Testosterone Injection The metabolism of Everolimus can be increased when combined with Testosterone. |
Oritavancin Injection | Oritavancin Injection The metabolism of Everolimus can be increased when combined with Oritavancin. |
Empagliflozin | Empagliflozin The therapeutic efficacy of Empagliflozin can be decreased when used in combination with Everolimus. |
Vorapaxar | Vorapaxar The serum concentration of Everolimus can be increased when it is combined with Vorapaxar. |
Hydrocodone | Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Everolimus. |
Suvorexant | Suvorexant The serum concentration of Everolimus can be increased when it is combined with Suvorexant. |
Dulaglutide Injection | Dulaglutide Injection The therapeutic efficacy of Dulaglutide can be decreased when used in combination with Everolimus. |
Edoxaban | Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Everolimus. |
Peginterferon Beta-1a Injection | Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Peginterferon beta-1a. |
Olaparib | Olaparib The metabolism of Everolimus can be decreased when combined with Olaparib. |
Blinatumomab Injection | Blinatumomab Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Blinatumomab. |
Caspofungin Injection | Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Everolimus. |
Methamphetamine | Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Everolimus. |
Tasimelteon | Tasimelteon The metabolism of Everolimus can be decreased when combined with Tasimelteon. |
Lanreotide Injection | Lanreotide Injection The metabolism of Everolimus can be decreased when combined with Lanreotide. |
Pirfenidone | Pirfenidone The risk or severity of adverse effects can be increased when Everolimus is combined with Pirfenidone. |
Nintedanib | Nintedanib The metabolism of Everolimus can be decreased when combined with Nintedanib. |
Secukinumab Injection | Secukinumab Injection The metabolism of Everolimus can be increased when combined with Secukinumab. |
Risperidone Injection | Risperidone Injection The metabolism of Risperidone can be decreased when combined with Everolimus. |
Palbociclib | Palbociclib The serum concentration of Everolimus can be increased when it is combined with Palbociclib. |
Insulin Human Inhalation | Insulin Human Inhalation The therapeutic efficacy of Insulin human can be decreased when used in combination with Everolimus. |
Lenvatinib | Lenvatinib The metabolism of Everolimus can be increased when combined with Lenvatinib. |
Panobinostat | Panobinostat The risk or severity of adverse effects can be increased when Panobinostat is combined with Everolimus. |
Dinutuximab Injection | Dinutuximab Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Dinutuximab. |
Haloperidol Injection | Haloperidol Injection The metabolism of Everolimus can be decreased when combined with Haloperidol. |
Isavuconazonium Injection | Isavuconazonium Injection The metabolism of Everolimus can be decreased when combined with Isavuconazonium. |
Flibanserin | Flibanserin The serum concentration of Everolimus can be increased when it is combined with Flibanserin. |
Rolapitant | Rolapitant The serum concentration of Everolimus can be increased when it is combined with Rolapitant. |
Prednisolone | Prednisolone The serum concentration of Everolimus can be increased when it is combined with Prednisolone. |
Daclatasvir | Daclatasvir The serum concentration of Everolimus can be increased when it is combined with Daclatasvir. |
Brexpiprazole | Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Everolimus. |
Ziprasidone Injection | Ziprasidone Injection The metabolism of Everolimus can be decreased when combined with Ziprasidone. |
Cariprazine | Cariprazine The metabolism of Cariprazine can be decreased when combined with Everolimus. |
Eluxadoline | Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Everolimus. |
Insulin Degludec (rDNA Origin) Injection | Insulin Degludec (rDNA Origin) Injection The therapeutic efficacy of Insulin degludec can be decreased when used in combination with Everolimus. |
Cobimetinib | Cobimetinib The metabolism of Everolimus can be decreased when combined with Cobimetinib. |
Mepolizumab Injection | Mepolizumab Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Mepolizumab. |
Trabectedin Injection | Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Everolimus. |
Osimertinib | Osimertinib The metabolism of Everolimus can be increased when combined with Osimertinib. |
Rifapentine | Rifapentine The metabolism of Everolimus can be increased when combined with Rifapentine. |
Lesinurad | Lesinurad The metabolism of Everolimus can be increased when combined with Lesinurad. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection The metabolism of Everolimus can be decreased when combined with Amphotericin B. |
Dexamethasone Injection | Dexamethasone Injection The metabolism of Everolimus can be increased when combined with Dexamethasone. |
Defibrotide Injection | Defibrotide Injection The risk or severity of bleeding can be increased when Defibrotide is combined with Everolimus. |
Ixekizumab Injection | Ixekizumab Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Ixekizumab. |
Venetoclax | Venetoclax The metabolism of Everolimus can be decreased when combined with Venetoclax. |
Cobicistat | Cobicistat The serum concentration of Everolimus can be increased when it is combined with Cobicistat. |
Selexipag | Selexipag The serum concentration of Selexipag can be increased when it is combined with Everolimus. |
Diphenhydramine Injection | Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Everolimus. |
Rucaparib | Rucaparib The serum concentration of Everolimus can be increased when it is combined with Rucaparib. |
Lixisenatide Injection | Lixisenatide Injection The therapeutic efficacy of Lixisenatide can be decreased when used in combination with Everolimus. |
Ribociclib | Ribociclib The metabolism of Everolimus can be decreased when combined with Ribociclib. |
Brodalumab Injection | Brodalumab Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Brodalumab. |
Brigatinib | Brigatinib The metabolism of Everolimus can be increased when combined with Brigatinib. |
Doxepin (Insomnia) | Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Everolimus. |
Deutetrabenazine | Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Everolimus. |
Valbenazine | Valbenazine The metabolism of Valbenazine can be decreased when combined with Everolimus. |
Deflazacort | Deflazacort The serum concentration of Everolimus can be increased when it is combined with Deflazacort. |
Ocrelizumab Injection | Ocrelizumab Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Ocrelizumab. |
Sarilumab Injection | Sarilumab Injection The metabolism of Everolimus can be increased when combined with Sarilumab. |
Midostaurin | Midostaurin The metabolism of Everolimus can be increased when combined with Midostaurin. |
Neratinib | Neratinib The serum concentration of Everolimus can be increased when it is combined with Neratinib. |
Guselkumab Injection | Guselkumab Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Guselkumab. |
Enasidenib | Enasidenib The serum concentration of Everolimus can be increased when it is combined with Enasidenib. |
Inotuzumab Ozogamicin Injection | Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Everolimus. |
Aprepitant/Fosaprepitant Injection | Aprepitant/Fosaprepitant Injection The metabolism of Everolimus can be increased when combined with Fosaprepitant. |
Copanlisib Injection | Copanlisib Injection The serum concentration of Copanlisib can be increased when it is combined with Everolimus. |
Abemaciclib | Abemaciclib The serum concentration of Abemaciclib can be increased when it is combined with Everolimus. |
Betrixaban | Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Everolimus. |
Acalabrutinib | Acalabrutinib The metabolism of Everolimus can be decreased when combined with Acalabrutinib. |
Gemtuzumab Ozogamicin Injection | Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Everolimus. |
Letermovir | Letermovir The metabolism of Letermovir can be decreased when combined with Everolimus. |
Semaglutide Injection | Semaglutide Injection The therapeutic efficacy of Semaglutide can be decreased when used in combination with Everolimus. |
Tetrabenazine | Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Everolimus. |
Ertugliflozin | Ertugliflozin The serum concentration of Ertugliflozin can be increased when it is combined with Everolimus. |
Buprenorphine Injection | Buprenorphine Injection The metabolism of Everolimus can be decreased when combined with Buprenorphine. |
Apalutamide | Apalutamide The metabolism of Everolimus can be increased when combined with Apalutamide. |
Penicillamine | Penicillamine The risk or severity of adverse effects can be increased when Penicillamine is combined with Everolimus. |
Fostamatinib | Fostamatinib The metabolism of Everolimus can be decreased when combined with Fostamatinib. |
Avatrombopag | Avatrombopag The serum concentration of Avatrombopag can be increased when it is combined with Everolimus. |
Baricitinib | Baricitinib The risk or severity of adverse effects can be increased when Baricitinib is combined with Everolimus. |
Lofexidine | Lofexidine The metabolism of Lofexidine can be decreased when combined with Everolimus. |
Eliglustat | Eliglustat The metabolism of Everolimus can be decreased when combined with Eliglustat. |
Encorafenib | Encorafenib The metabolism of Encorafenib can be decreased when combined with Everolimus. |
Binimetinib | Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Everolimus. |
Ivosidenib | Ivosidenib The serum concentration of Everolimus can be increased when it is combined with Ivosidenib. |
Lusutrombopag | Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Everolimus. |
Elagolix | Elagolix The serum concentration of Elagolix can be increased when it is combined with Everolimus. |
Tafenoquine | Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Everolimus. |
Dacomitinib | Dacomitinib The serum concentration of Everolimus can be increased when it is combined with Dacomitinib. |
Duvelisib | Duvelisib The metabolism of Everolimus can be decreased when combined with Duvelisib. |
Omadacycline | Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Everolimus. |
Sarecycline | Sarecycline The serum concentration of Everolimus can be increased when it is combined with Sarecycline. |
Stiripentol | Stiripentol The metabolism of Everolimus can be decreased when combined with Stiripentol. |
Talazoparib | Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Everolimus. |
Gilteritinib | Gilteritinib The metabolism of Everolimus can be decreased when combined with Gilteritinib. |
Glasdegib | Glasdegib The serum concentration of Everolimus can be increased when it is combined with Glasdegib. |
Larotrectinib | Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Everolimus. |
Methoxy Polyethylene Glycol-Epoetin Beta Injection | Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Everolimus. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The metabolism of Everolimus can be increased when combined with Paclitaxel. |
Rifamycin | Rifamycin The metabolism of Everolimus can be increased when combined with Rifamycin. |
Prucalopride | Prucalopride The metabolism of Prucalopride can be decreased when combined with Everolimus. |
Ravulizumab-cwvz Injection | Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Ravulizumab. |
Emapalumab-lzsg Injection | Emapalumab-lzsg Injection The metabolism of Everolimus can be increased when combined with Emapalumab. |
Siponimod | Siponimod The risk or severity of adverse effects can be increased when Everolimus is combined with Siponimod. |
Caplacizumab-yhdp Injection | Caplacizumab-yhdp Injection The risk or severity of bleeding can be increased when Caplacizumab is combined with Everolimus. |
Erdafitinib | Erdafitinib The serum concentration of Everolimus can be increased when it is combined with Erdafitinib. |
Risankizumab-rzaa Injection | Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Risankizumab. |
Alpelisib | Alpelisib The metabolism of Everolimus can be increased when combined with Alpelisib. |
Cladribine | Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Everolimus. |
Darolutamide | Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Everolimus. |
Triclabendazole | Triclabendazole The metabolism of Everolimus can be decreased when combined with Triclabendazole. |
Entrectinib | Entrectinib The serum concentration of Everolimus can be increased when it is combined with Entrectinib. |
Istradefylline | Istradefylline The serum concentration of Everolimus can be increased when it is combined with Istradefylline. |
Pitolisant | Pitolisant The serum concentration of Everolimus can be decreased when it is combined with Pitolisant. |
Fedratinib | Fedratinib The serum concentration of Everolimus can be increased when it is combined with Fedratinib. |
Lefamulin | Lefamulin The serum concentration of Lefamulin can be increased when it is combined with Everolimus. |
Phenytoin Injection | Phenytoin Injection The metabolism of Everolimus can be increased when combined with Phenytoin. |
Fosphenytoin Injection | Fosphenytoin Injection The metabolism of Everolimus can be increased when combined with Fosphenytoin. |
Enfortumab vedotin-ejfv Injection | Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Everolimus. |
Voxelotor | Voxelotor The serum concentration of Everolimus can be increased when it is combined with Voxelotor. |
Lasmiditan | Lasmiditan The serum concentration of Everolimus can be increased when it is combined with Lasmiditan. |
Ubrogepant | Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Everolimus. |
Tazemetostat | Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Everolimus. |
Bempedoic Acid | Bempedoic Acid The excretion of Bempedoic acid can be decreased when combined with Everolimus. |
Cenobamate | Cenobamate The serum concentration of Everolimus can be decreased when it is combined with Cenobamate. |
Ozanimod | Ozanimod The risk or severity of adverse effects can be increased when Everolimus is combined with Ozanimod. |
Selumetinib | Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Everolimus. |
Rimegepant | Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Everolimus. |
Tucatinib | Tucatinib Everolimus may decrease the excretion rate of Tucatinib which could result in a higher serum level. |
Remdesivir Injection | Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Everolimus. |
Ripretinib | Ripretinib The serum concentration of Everolimus can be increased when it is combined with Ripretinib. |
Capmatinib | Capmatinib The serum concentration of Everolimus can be increased when it is combined with Capmatinib. |
Lemborexant | Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Everolimus. |
Fostemsavir | Fostemsavir The serum concentration of Fostemsavir can be increased when it is combined with Everolimus. |
Octreotide | Octreotide The serum concentration of Everolimus can be increased when it is combined with Octreotide. |
Belantamab Mafodotin-blmf Injection | Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Everolimus. |
Pralsetinib | Pralsetinib The serum concentration of Everolimus can be increased when it is combined with Pralsetinib. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Everolimus can be decreased when it is combined with Satralizumab. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Everolimus can be decreased when combined with Drospirenone. |
Vitamin E (Alpha-Tocopherol) | Vitamin E (Alpha-Tocopherol) The metabolism of Everolimus can be increased when combined with Vitamin E. |
Theophylline | Theophylline The metabolism of Theophylline can be decreased when combined with Everolimus. |
Indomethacin | Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Everolimus. |
Trazodone | Trazodone The serum concentration of Trazodone can be decreased when it is combined with Everolimus. |
Hydroxyurea | Hydroxyurea The risk or severity of adverse effects can be increased when Hydroxyurea is combined with Everolimus. |
Floxuridine | Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Everolimus. |
Phenobarbital | Phenobarbital The metabolism of Everolimus can be increased when combined with Phenobarbital. |
Methotrexate Injection | Methotrexate Injection The risk or severity of adverse effects can be increased when Methotrexate is combined with Everolimus. |
Primidone | Primidone The metabolism of Everolimus can be increased when combined with Primidone. |
Chlorpromazine | Chlorpromazine The metabolism of Everolimus can be increased when combined with Chlorpromazine. |
Diazepam | Diazepam The metabolism of Everolimus can be decreased when combined with Diazepam. |
Lorazepam | Lorazepam The metabolism of Everolimus can be decreased when combined with Lorazepam. |
Carmustine | Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with Everolimus. |
Codeine | Codeine The metabolism of Codeine can be decreased when combined with Everolimus. |
Bromocriptine | Bromocriptine The metabolism of Everolimus can be decreased when combined with Bromocriptine. |
Tranylcypromine | Tranylcypromine The metabolism of Everolimus can be decreased when combined with Tranylcypromine. |
Phenelzine | Phenelzine The metabolism of Everolimus can be decreased when combined with Phenelzine. |
Procarbazine | Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Everolimus. |
Ergoloid Mesylates | Ergoloid Mesylates The serum concentration of Ergoloid mesylate can be increased when it is combined with Everolimus. |
Tetracycline | Tetracycline The metabolism of Everolimus can be decreased when combined with Tetracycline. |
Thioguanine | Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Everolimus. |
Prochlorperazine | Prochlorperazine The metabolism of Everolimus can be decreased when combined with Prochlorperazine. |
Thioridazine | Thioridazine The metabolism of Thioridazine can be decreased when combined with Everolimus. |
Bleomycin | Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Everolimus. |
Sulfadiazine | Sulfadiazine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Everolimus. |
Oxycodone | Oxycodone The metabolism of Oxycodone can be decreased when combined with Everolimus. |
Methadone | Methadone The metabolism of Everolimus can be increased when combined with Methadone. |
Oxybutynin | Oxybutynin The metabolism of Everolimus can be decreased when combined with Oxybutynin. |
Benztropine | Benztropine The metabolism of Benzatropine can be decreased when combined with Everolimus. |
Maprotiline | Maprotiline The metabolism of Maprotiline can be decreased when combined with Everolimus. |
Orphenadrine | Orphenadrine The metabolism of Everolimus can be decreased when combined with Orphenadrine. |
Perphenazine | Perphenazine The metabolism of Perphenazine can be decreased when combined with Everolimus. |
Azathioprine | Azathioprine The risk or severity of adverse effects can be increased when Azathioprine is combined with Everolimus. |
Phentermine | Phentermine The metabolism of Everolimus can be decreased when combined with Phentermine. |
Amoxapine | Amoxapine The metabolism of Amoxapine can be decreased when combined with Everolimus. |
Sulfasalazine | Sulfasalazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Everolimus. |
Hydrocortisone | Hydrocortisone The serum concentration of Everolimus can be increased when it is combined with Hydrocortisone. |
Lomustine | Lomustine The risk or severity of adverse effects can be increased when Lomustine is combined with Everolimus. |
Doxorubicin | Doxorubicin The metabolism of Everolimus can be decreased when combined with Doxorubicin. |
Cytarabine | Cytarabine The risk or severity of adverse effects can be increased when Cytarabine is combined with Everolimus. |
Mechlorethamine | Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Everolimus. |
Dactinomycin | Dactinomycin The risk or severity of adverse effects can be increased when Dactinomycin is combined with Everolimus. |
Carbamazepine | Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Everolimus. |
Clonidine | Clonidine The metabolism of Clonidine can be decreased when combined with Everolimus. |
Hydralazine | Hydralazine The metabolism of Everolimus can be decreased when combined with Hydralazine. |
Cimetidine | Cimetidine The metabolism of Cimetidine can be decreased when combined with Everolimus. |
Warfarin | Warfarin The serum concentration of Everolimus can be increased when it is combined with Warfarin. |
Loperamide | Loperamide The metabolism of Loperamide can be decreased when combined with Everolimus. |
Promethazine | Promethazine The metabolism of Promethazine can be decreased when combined with Everolimus. |
Daunorubicin | Daunorubicin The metabolism of Everolimus can be decreased when combined with Daunorubicin. |
Griseofulvin | Griseofulvin The metabolism of Everolimus can be increased when combined with Griseofulvin. |
Digoxin | Digoxin The serum concentration of Digoxin can be increased when it is combined with Everolimus. |
Loxapine | Loxapine The serum concentration of Everolimus can be increased when it is combined with Loxapine. |
Chloroquine | Chloroquine The metabolism of Chloroquine can be decreased when combined with Everolimus. |
Quinine | Quinine The serum concentration of Quinine can be increased when it is combined with Everolimus. |
Calcitriol | Calcitriol The metabolism of Everolimus can be increased when combined with Calcitriol. |
Lactulose | Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Everolimus. |
Sulfinpyrazone | Sulfinpyrazone The metabolism of Everolimus can be increased when combined with Sulfinpyrazone. |
Chlorothiazide | Chlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Chlorothiazide is combined with Everolimus. |
Secobarbital | Secobarbital The metabolism of Everolimus can be increased when combined with Secobarbital. |
Desipramine | Desipramine The metabolism of Everolimus can be decreased when combined with Desipramine. |
Amitriptyline | Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Everolimus. |
Imipramine | Imipramine The metabolism of Imipramine can be decreased when combined with Everolimus. |
Probenecid | Probenecid The metabolism of Everolimus can be increased when combined with Probenecid. |
Quinidine | Quinidine The serum concentration of Quinidine can be increased when it is combined with Everolimus. |
Procainamide | Procainamide The metabolism of Procainamide can be decreased when combined with Everolimus. |
Isoniazid | Isoniazid The metabolism of Everolimus can be decreased when combined with Isoniazid. |
Rifampin | Rifampin The metabolism of Everolimus can be increased when combined with Rifampicin. |
Disopyramide | Disopyramide Everolimus may increase the QTc-prolonging activities of Disopyramide. |
Valproic Acid | Valproic Acid The metabolism of Everolimus can be decreased when combined with Valproic acid. |
Tamoxifen | Tamoxifen The serum concentration of Everolimus can be increased when it is combined with Tamoxifen. |
Mitomycin | Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Everolimus. |
Levothyroxine | Levothyroxine The serum concentration of Everolimus can be decreased when it is combined with Levothyroxine. |
Liothyronine | Liothyronine The excretion of Liothyronine can be decreased when combined with Everolimus. |
Methimazole | Methimazole The metabolism of Everolimus can be decreased when combined with Methimazole. |
Propylthiouracil | Propylthiouracil The risk or severity of adverse effects can be increased when Propylthiouracil is combined with Everolimus. |
Chlorpropamide | Chlorpropamide The therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Everolimus. |
Tolbutamide | Tolbutamide The therapeutic efficacy of Tolbutamide can be decreased when used in combination with Everolimus. |
Tolazamide | Tolazamide The therapeutic efficacy of Tolazamide can be decreased when used in combination with Everolimus. |
Dextromethorphan | Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Everolimus. |
Dinoprostone | Dinoprostone The excretion of Dinoprostone can be decreased when combined with Everolimus. |
Niacin | Niacin The metabolism of Everolimus can be decreased when combined with Niacin. |
Chlorpheniramine | Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Everolimus. |
Meclizine | Meclizine The metabolism of Meclizine can be decreased when combined with Everolimus. |
Methyclothiazide | Methyclothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Everolimus. |
Hydrochlorothiazide | Hydrochlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Hydrochlorothiazide is combined with Everolimus. |
Chlorzoxazone | Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Everolimus. |
Danazol | Danazol The metabolism of Everolimus can be decreased when combined with Danazol. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Everolimus. |
Nortriptyline | Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Everolimus. |
Amphotericin B Injection | Amphotericin B Injection The metabolism of Everolimus can be decreased when combined with Amphotericin B. |
Mercaptopurine | Mercaptopurine The risk or severity of adverse effects can be increased when Mercaptopurine is combined with Everolimus. |
Nadolol | Nadolol The metabolism of Nadolol can be decreased when combined with Everolimus. |
Allopurinol | Allopurinol The risk or severity of adverse effects can be increased when Allopurinol is combined with Everolimus. |
Clomiphene | Clomiphene The serum concentration of Everolimus can be increased when it is combined with Clomifene. |
Fluorouracil Injection | Fluorouracil Injection The risk or severity of adverse effects can be increased when Fluorouracil is combined with Everolimus. |
Colchicine | Colchicine The metabolism of Colchicine can be decreased when combined with Everolimus. |
Cephalexin | Cephalexin The metabolism of Everolimus can be decreased when combined with Cephalexin. |
Dacarbazine | Dacarbazine The risk or severity of adverse effects can be increased when Dacarbazine is combined with Everolimus. |
Acetazolamide | Acetazolamide The metabolism of Everolimus can be decreased when combined with Acetazolamide. |
Bacillus Calmette-Guerin (BCG) Vaccine | Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Everolimus. |
Ketoconazole | Ketoconazole The serum concentration of Everolimus can be increased when it is combined with Ketoconazole. |
Thiotepa Injection | Thiotepa Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Thiotepa. |
Vincristine Injection | Vincristine Injection The risk or severity of adverse effects can be increased when Everolimus is combined with Vincristine. |
Captopril | Captopril The risk or severity of adverse effects can be increased when Everolimus is combined with Captopril. |
Dipyridamole | Dipyridamole The risk or severity of bleeding can be increased when Dipyridamole is combined with Everolimus. |
Vinblastine | Vinblastine The metabolism of Vinblastine can be increased when combined with Everolimus. |
Metoprolol | Metoprolol The metabolism of Everolimus can be decreased when combined with Metoprolol. |
Aspirin | Aspirin The risk or severity of bleeding can be increased when Acetylsalicylic acid is combined with Everolimus. |
Chlorambucil | Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Everolimus. |
Alprazolam | Alprazolam The metabolism of Alprazolam can be decreased when combined with Everolimus. |
Triazolam | Triazolam The serum concentration of Triazolam can be increased when it is combined with Everolimus. |
Diltiazem | Diltiazem The metabolism of Everolimus can be decreased when combined with Diltiazem. |
Nifedipine | Nifedipine The metabolism of Everolimus can be increased when combined with Nifedipine. |
Timolol | Timolol The metabolism of Timolol can be decreased when combined with Everolimus. |
Verapamil | Verapamil The serum concentration of Everolimus can be increased when it is combined with Verapamil. |
Atenolol | Atenolol The metabolism of Atenolol can be decreased when combined with Everolimus. |
Pindolol | Pindolol The metabolism of Pindolol can be decreased when combined with Everolimus. |
Cisplatin Injection | Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Everolimus. |
Streptozocin | Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Everolimus. |
Etoposide | Etoposide The metabolism of Etoposide can be increased when combined with Everolimus. |
Glyburide | Glyburide The metabolism of Everolimus can be decreased when combined with Glyburide. |
Glipizide | Glipizide The therapeutic efficacy of Glipizide can be decreased when used in combination with Everolimus. |
Dicloxacillin | Dicloxacillin The metabolism of Everolimus can be increased when combined with Dicloxacillin. |
Nafcillin Injection | Nafcillin Injection The metabolism of Everolimus can be increased when combined with Nafcillin. |
Pentoxifylline | Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Everolimus. |
Pentamidine Injection | Pentamidine Injection The therapeutic efficacy of Pentamidine can be decreased when used in combination with Everolimus. |
Labetalol | Labetalol The metabolism of Labetalol can be decreased when combined with Everolimus. |
Pimozide | Pimozide The metabolism of Everolimus can be decreased when combined with Pimozide. |
Enalapril | Enalapril The risk or severity of adverse effects can be increased when Everolimus is combined with Enalapril. |
Amiodarone | Amiodarone The serum concentration of Everolimus can be increased when it is combined with Amiodarone. |
Buspirone | Buspirone The metabolism of Buspirone can be decreased when combined with Everolimus. |
Lovastatin | Lovastatin The metabolism of Everolimus can be decreased when combined with Lovastatin. |
Ciprofloxacin | Ciprofloxacin The metabolism of Ciprofloxacin can be decreased when combined with Everolimus. |
Fluoxetine | Fluoxetine The metabolism of Fluoxetine can be decreased when combined with Everolimus. |
Interferon Alfa-2b Injection | Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Everolimus. |
Clozapine | Clozapine The metabolism of Clozapine can be decreased when combined with Everolimus. |
Estazolam | Estazolam The serum concentration of Estazolam can be increased when it is combined with Everolimus. |
Idarubicin | Idarubicin The risk or severity of adverse effects can be increased when Idarubicin is combined with Everolimus. |
Fludarabine Injection | Fludarabine Injection The risk or severity of adverse effects can be increased when Fludarabine is combined with Everolimus. |
Pentostatin Injection | Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Everolimus. |
Clarithromycin | Clarithromycin The serum concentration of Everolimus can be increased when it is combined with Clarithromycin. |
Benazepril | Benazepril The risk or severity of adverse effects can be increased when Everolimus is combined with Benazepril. |
Felodipine | Felodipine The metabolism of Everolimus can be decreased when combined with Felodipine. |
Fosinopril | Fosinopril The risk or severity of adverse effects can be increased when Everolimus is combined with Fosinopril. |
Pravastatin | Pravastatin The serum concentration of Pravastatin can be increased when it is combined with Everolimus. |
Quinapril | Quinapril The risk or severity of adverse effects can be increased when Everolimus is combined with Quinapril. |
Ramipril | Ramipril The risk or severity of adverse effects can be increased when Everolimus is combined with Ramipril. |
Simvastatin | Simvastatin The serum concentration of Everolimus can be increased when it is combined with Simvastatin. |
Epoetin Alfa, Injection | Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Everolimus. |
Teniposide Injection | Teniposide Injection The metabolism of Everolimus can be decreased when combined with Teniposide. |
Itraconazole | Itraconazole The serum concentration of Everolimus can be increased when it is combined with Itraconazole. |
Lisinopril | Lisinopril The risk or severity of adverse effects can be increased when Everolimus is combined with Lisinopril. |
Rifabutin | Rifabutin The metabolism of Everolimus can be increased when combined with Rifabutin. |
Sotalol | Sotalol The metabolism of Sotalol can be decreased when combined with Everolimus. |
Bisoprolol | Bisoprolol The serum concentration of Everolimus can be increased when it is combined with Bisoprolol. |
Zolpidem | Zolpidem The metabolism of Zolpidem can be decreased when combined with Everolimus. |
Doxazosin | Doxazosin The metabolism of Everolimus can be decreased when combined with Doxazosin. |
Isradipine | Isradipine The metabolism of Everolimus can be decreased when combined with Isradipine. |
Omeprazole | Omeprazole The metabolism of Everolimus can be increased when combined with Omeprazole. |
Cisapride | Cisapride The serum concentration of Cisapride can be increased when it is combined with Everolimus. |
Fluvastatin | Fluvastatin The metabolism of Everolimus can be decreased when combined with Fluvastatin. |
Venlafaxine | Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Everolimus. |
Famciclovir | Famciclovir The metabolism of Everolimus can be decreased when combined with Famciclovir. |
Fluvoxamine | Fluvoxamine The metabolism of Everolimus can be decreased when combined with Fluvoxamine. |
Nefazodone | Nefazodone The metabolism of Everolimus can be decreased when combined with Nefazodone. |
Losartan | Losartan The metabolism of Everolimus can be decreased when combined with Losartan. |
Tramadol | Tramadol The metabolism of Everolimus can be decreased when combined with Tramadol. |
Vinorelbine Injection | Vinorelbine Injection The risk or severity of adverse effects can be increased when Vinorelbine is combined with Everolimus. |
Carboplatin Injection | Carboplatin Injection The risk or severity of adverse effects can be increased when Carboplatin is combined with Everolimus. |
Moexipril | Moexipril The risk or severity of adverse effects can be increased when Everolimus is combined with Moexipril. |
Lansoprazole | Lansoprazole The metabolism of Everolimus can be increased when combined with Lansoprazole. |
Ifosfamide Injection | Ifosfamide Injection The metabolism of Everolimus can be increased when combined with Ifosfamide. |
Pegaspargase Injection | Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Everolimus. |
Nicardipine | Nicardipine The metabolism of Everolimus can be decreased when combined with Nicardipine. |
Ticlopidine | Ticlopidine The metabolism of Everolimus can be decreased when combined with Ticlopidine. |
Saquinavir | Saquinavir The serum concentration of Everolimus can be increased when it is combined with Saquinavir. |
Metformin | Metformin The therapeutic efficacy of Metformin can be decreased when used in combination with Everolimus. |
Dalteparin Injection | Dalteparin Injection The risk or severity of bleeding can be increased when Dalteparin is combined with Everolimus. |
Acarbose | Acarbose The therapeutic efficacy of Acarbose can be decreased when used in combination with Everolimus. |
Glimepiride | Glimepiride The therapeutic efficacy of Glimepiride can be decreased when used in combination with Everolimus. |
Gemcitabine Injection | Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Everolimus. |
Ritonavir | Ritonavir The serum concentration of Everolimus can be increased when it is combined with Ritonavir. |
Docetaxel Injection | Docetaxel Injection The metabolism of Everolimus can be decreased when combined with Docetaxel. |
Clomipramine | Clomipramine The metabolism of Clomipramine can be decreased when combined with Everolimus. |
Zafirlukast | Zafirlukast The metabolism of Everolimus can be decreased when combined with Zafirlukast. |
Mirtazapine | Mirtazapine The metabolism of Mirtazapine can be decreased when combined with Everolimus. |
Trandolapril | Trandolapril The risk or severity of adverse effects can be increased when Everolimus is combined with Trandolapril. |
Topiramate | Topiramate The metabolism of Everolimus can be increased when combined with Topiramate. |
Valsartan | Valsartan The excretion of Valsartan can be decreased when combined with Everolimus. |
Insulin Lispro Injection | Insulin Lispro Injection The therapeutic efficacy of Insulin lispro can be decreased when used in combination with Everolimus. |
Donepezil | Donepezil The metabolism of Everolimus can be decreased when combined with Donepezil. |
Fexofenadine | Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Everolimus. |
Azithromycin | Azithromycin The metabolism of Everolimus can be decreased when combined with Azithromycin. |
Carvedilol | Carvedilol The serum concentration of Everolimus can be increased when it is combined with Carvedilol. |
Selegiline | Selegiline The metabolism of Selegiline can be decreased when combined with Everolimus. |
Bicalutamide | Bicalutamide The metabolism of Everolimus can be decreased when combined with Bicalutamide. |
Sertraline | Sertraline The metabolism of Sertraline can be decreased when combined with Everolimus. |
Propafenone | Propafenone The serum concentration of Everolimus can be increased when it is combined with Propafenone. |
Raloxifene | Raloxifene The metabolism of Raloxifene can be decreased when combined with Everolimus. |
Irbesartan | Irbesartan The metabolism of Everolimus can be decreased when combined with Irbesartan. |
Tamsulosin | Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Everolimus. |
Quetiapine | Quetiapine The metabolism of Everolimus can be decreased when combined with Quetiapine. |
Paroxetine | Paroxetine The metabolism of Everolimus can be decreased when combined with Paroxetine. |
Citalopram | Citalopram The metabolism of Everolimus can be decreased when combined with Citalopram. |
Capecitabine | Capecitabine The risk or severity of adverse effects can be increased when Capecitabine is combined with Everolimus. |
Efavirenz | Efavirenz The serum concentration of Everolimus can be decreased when it is combined with Efavirenz. |
Sildenafil | Sildenafil The serum concentration of Everolimus can be increased when it is combined with Sildenafil. |
Pioglitazone | Pioglitazone The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Everolimus. |
Trastuzumab Injection | Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Everolimus. |
Celecoxib | Celecoxib The metabolism of Everolimus can be decreased when combined with Celecoxib. |
Rosiglitazone | Rosiglitazone The therapeutic efficacy of Rosiglitazone can be decreased when used in combination with Everolimus. |
Tolterodine | Tolterodine The metabolism of Tolterodine can be decreased when combined with Everolimus. |
Thalidomide | Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Everolimus. |
Nateglinide | Nateglinide The metabolism of Nateglinide can be decreased when combined with Everolimus. |
Galantamine | Galantamine The metabolism of Galantamine can be decreased when combined with Everolimus. |
Rabeprazole | Rabeprazole The metabolism of Everolimus can be decreased when combined with Rabeprazole. |
Terbinafine | Terbinafine The metabolism of Everolimus can be increased when combined with Terbinafine. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists